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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6764-6772

3D-QSAR and docking studies on pyrazolo[4,3-h]qinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors

(5) Lan, Ping a Chen, Wan Na a Xiao, Gao Keng a Sun, Ping Hua a Chen, Wei Min a

a JINAN UNIVERSITY (China)

Author keywords

3D QSAR; CoMFA; CoMSIA; Cyclin dependent kinase; Docking

Indexed keywords

AMIDE; CYCLIN DEPENDENT KINASE 2 INHIBITOR; PYRAZOLO[4,3 H]QINAZOLIN 3 CARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; CORRELATION COEFFICIENT; ELECTRIC FIELD; ELECTRIC POTENTIAL; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DOCKING; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

AMIDES; CYCLIN-DEPENDENT KINASE 2; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PYRAZOLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINAZOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77958075936 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.08.131 Document Type: Article

Times cited : (38)

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