The association of the Clock 3111 T/C SNP with lipids and lipoproteins including small dense low-density lipoprotein: Results from the Mima study

BMC Medical Genetics

Volumn 11, Issue 1, 2010, Pages

  Tsuzaki, Kokoro ^a   Kotani, Kazuhiko ^a   Sano, Yoshiko ^a   Fujiwara, Shinji ^b   Takahashi, Kaoru ^a   Sakane, Naoki ^a  

^a NATIONAL HOSPITAL ORGANIZATION KYOTO MEDICAL CENTER   (Japan)

^b Mima City National Health Insurance Koyadaira Clinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN; PRIMER DNA; TRANSCRIPTION FACTOR CLOCK; LIPOPROTEIN;

ADULT; ARTICLE; CONTROLLED STUDY; ELECTROPHORESIS; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; OBESITY; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; GENETICS; LIPID METABOLISM; METABOLISM; MIDDLE AGED; PROTEIN BINDING;

AGED; CLOCK PROTEINS; FEMALE; GENOTYPE; HUMANS; LIPID METABOLISM; LIPOPROTEINS; LIPOPROTEINS, LDL; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING;

EID: 77958057810     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-150     Document Type: Article

References (40)

1. Borbely AA. A two process model of sleep regulation. Hum Neurobiol 1982, 1:195-204.
2. Daan S, Beersma DG, Borbey AA. Timing of human sleep: recovery process gated by circadian pacemaker. Am J Physiol 1984, 246:R161-183.
3. Gachon F, Nagoshi E, Brown SA, Ripperger J. The mammalian circadian timing system: from gene expression to physiology. Chtomosoma 2004, 113:103-112.
4. King DP, Takahashi JS. Molecular genetics of circadian rhythms in mammals. Annu Rev Neurosci 2000, 23:713-742. 10.1146/annurev.neuro.23.1.713, 10845079.
5. Wager-Smith K, Kay SA. Circadian rhythm genetics: from files to mice to humans. Nat Genet 2000, 26:23-27. 10.1038/79134, 10973243.
6. Schibler U, Sassone-Corsi P. A web of circadian pacemakers. Cell 2002, 111:919-922. 10.1016/S0092-8674(02)01225-4, 12507418.
7. Lowrey PL, Takahashi JS. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genomics Hum Genet 2004, 5:407-441. 10.1146/annurev.genom.5.061903.175925, 15485355.
8. Balsalobre A. Clock genes in mammalian peripheral tissues. Cell Tissue Res 2002, 309:193-199. 10.1007/s00441-002-0585-0, 12111549.
9. Lamia KA, Storch KF, Weitz CJ. Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci 2008, 105:15172-15177. 10.1073/pnas.0806717105, 2532700, 18779586.
10. Yang X, Downes M, Yu RT, et al. Nuclear receptor expression links the circadian clock to metabolism. Cell 2006, 126:801-810. 10.1016/j.cell.2006.06.050, 16923398.
11. Turek FW, Joshu C, Kohsaka A, et al. Obesity and metabolic syndrome in circadian Clock mutan mice. Science 2005, 308:1043-1045. 10.1126/science.1108750, 15845877.
12. Viterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, AcDonald JD, Dove WF, Pinto LH, Turkey FW. Mutagenesis and mapping of a mouse gene, clock, essential for circadian behavior. Science 1994, 264:6386-6391.
13. Katzenberg D, Young T, Finn L, Lin L, King DP, Takahashi JS, Mignot E. A CLOCK polymorphism associated with human diurnal preference. Sleep 1998, 21:569-576.
14. Robilliard DL, Archer SN, Arendt J, Lockley SW, Hack LM, English J, Leger D, Smits MG, Williams A, Skene DJ, Von Schantz M. The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects. J Sleep Res 2002, 11:305-312. 10.1046/j.1365-2869.2002.00320.x, 12464098.
15. Iwase T, Kajimura N, Uchiyama M, Ebisawa T, Yoshimura K, Kamai Y, et al. Mutation screening of the human Clock gene in circadian rhythm sleep disorders. Psychiatry Res 2002, 15:121-128.
16. Griffin B, et al. Metabolism of VLDL and LDL subclasses. Curr Opin Lipidol 1994, 5:200-206. 10.1097/00041433-199405030-00007, 7952914.
17. Haffner SM, Mykkanen L, Stern MP, Paidi M, Howard BV. Greater effect of diabetes on LDL size in women than in men. Diabetes Care 1994, 10:1164-1171.
18. Singh AT, Rainwater DL, Haffner SM, VandeBerg JL, Shelledy WR, Moore PH, Dyer TD. Effect of diabetes on lipoprotein size. Arterioscler Thromb Vasc Biol 1995, 15:1805-1811.
19. Yoshino G, Hirano T, Kazumi T. Atherogenic lipoproteins and diabetes mellitus. J Diabetes Complications 2002, 16:29-34. 10.1016/S1056-8727(01)00199-4, 11872363.
20. Matsui J, Tamasawa N, Tanabe J, Kasai N, Murakami H, Yamato K, Guan J, Suda T. LDL particle size and lipid composition are risk factors for microalbuminuria in normotensive and normocholesterolemic patients with type 2 diabetes. Diabetes Res Clin Pract 2004, 66:229-236. 10.1016/j.diabres.2004.03.011, 15536019.
21. Jenkins AJ, Rowley KG, Lyons TJ, Best JD, Hill MA, Klein RL. Lipoproteins and diabetic microvascular complications. Curr Pharm Des 2004, 10:3395-418. Review, 10.2174/1381612043383188, 15544524.
22. Gentile M, Panico S, Jossa F, Mattiello A, Ubaldi S, Marotta G, Pauciullo P, Rubba P. Postprandial lipaemia, metabolic syndrome and LDL particle size in urbanized South African blacks with and without coronary artery disease. QJM 2008, 101:111-119. 10.1093/qjmed/hcm137, 18194974.
23. Crouse JR, Parks JS, Schey HM, Kahl FR. Studies of low density lipoprotein molecular weight in human beings with coronary artery disease. J Lipid Res 1985, 26:566-574.
24. Austin MA, Breslow JL, Hennekens CH, Buring JE, Willett WC, Krauss RM. Low-density lipoprotein subclass patterns and risk of myocardial infarction. JAMA 1988, 260:1917-1920. 10.1001/jama.260.13.1917, 3418853.
25. Griffin MD, Sanders TA, Davies IG, Morgan LM, Millward DJ, Lewis F, Slaughter S, Cooper JA, Miller GJ, Griffin BA. Effects of altering the ratio of dietary n-6 to n-3 fatty acids on insulin sensitivity, lipoprotein size, and postprandial lipemia in men and postmenopausal women aged 45-70 y: the OPTILIP Study. Am J Clin Nutr 2006, 84:1290-1298.
26. Kawano M, Shono N, Yoshimura T, Yamaguchi M, Hirano T, Hisatomi A. Improved cardio-respiratory fitness correlates with changes in the number and size of small dense LDL: randomized controlled trial with exercise training and dietary instruction. Intern Med 2009, 48:25-32. 10.2169/internalmedicine.48.1527, 19122353.
27. Tsuzaki K, Kotani K, Fujiwara S, Sano Y, Matsuoka Y, Domichi M, Hamada T, Shimatsu A, Sakane N. The Trp64Arg polymorphism of beta3-adrenergic receptor gene is associated with increased small dense low-density lipoprotein in a rural Japanese population: the Mima study. Metabolism 2007, 56:1689-1693. 10.1016/j.metabol.2007.07.012, 17998022.
28. Hamada T, Kotani K, Fujiwara S, Sano Y, Domichi M, Tsuzaki K, Sakane N. The common -55 C/T polymorphism in the promoter region of the uncoupling protein 3 gene reduces prevalence of obesity and elevates serum high-density lipoprotein cholesterol levels in the general Japanese population. Metabolism 2008, 57:410-415. 10.1016/j.metabol.2007.10.019, 18249216.
29. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419. 10.1007/BF00280883, 3899825.
30. Son JE, Lee W, Min WK, Chun S, Lee YW, Park H. Distribution of low-density lipoprotein particle size in healthy Korean adult males. Clin Chem Lab Med 2004, 42:235-237. 10.1515/CCLM.2004.042, 15061367.
31. Rubic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, Fitzgerald GA. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLos Biol 2004, 2:e377. 10.1371/journal.pbio.0020377, 524471, 15523558.
32. Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDrmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, Eckel RH, Takahashi JS, Bass J. Obesity and metabolic syndrome in circadian Clock mutant mice. Science 2005, 308:1043-1045. 10.1126/science.1108750, 15845877.
33. Benedetti F, Dallaspezia S, Fulgosi MC, Lorenzi C, Serretti A, Barbini B, Colombo C, Smeraldi E. Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression. Am J Med Genet B Neuropsychiatr Genet 2007, 144B:631-635. 10.1002/ajmg.b.30475, 17221848.
34. Benedetti F, Serretti A, Colombo C, Barbini B, Lorenzi C, Campori E, Smeraldi E. Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression. Am J Med Genet B Neuropsychiatr Genet 2003, 123B:23-26. 10.1002/ajmg.b.20038, 14582141.
35. Serretti A, Cusin C, Benedetti F, Mandelli L, Pirovano A, Zanardi R, Colombo C, Smeraldi E. Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism. Am J Med Genet B Neuropsychiatr Genet 2005, 137B:36-39. 10.1002/ajmg.b.30130, 15952199.
36. Serretti A, Benedetti F, Mandelli L, Lorenzi C, Pirovano A, Colombo C, Smeraldi E. Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. Am J Med Genet B Neuropsychiatr Genet 2003, 121B:35-38. 10.1002/ajmg.b.20053, 12898572.
37. Mishima K, Tozawa T, Satoh K, Saito H, Mishima Y. The 3111 T/C polymorphism of hClock is associated with evening preference and delayed sleep timing in a Japanese sample. Am J Med Genet B Neuropsychiatr Genet 2005, 133B:101-104. 10.1002/ajmg.b.30110, 15578592.
38. Pirovano A, Lorenzi C, Serretin A, Plodia C, Landoni S, Catalano M, Smeraldi E. Two new rare variants in the circadian "clock" gene may influence sleep pattern. Genet Med 2005, 7:455-457. 10.1097/01.GIM.0000170996.58079.6D, 16024980.
39. Pedrazzoli M, Louzada FM, Pereira DS, Benedito-Silva AA, Lopez AR, Martynhak BJ, Korczak AL, Koike Bdel V, Barbosa AA, D'Almeida V, Tufik S. Clock polymorphisms and circadian rhythms phenotypes in a sample of the Brazilian population. Chronobiol Int 2007, 24:1-8. 10.1080/07420520601139789, 17364575.
40. Sookoian S, Gemma C, Gianotti TF, Burgueño A, Castaño G, Pirola CJ. Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 2008, 87:1606-15.