Tri- and tetrasubstituted imidazoles as p38α mitogen-activated protein kinase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 22, 2010, Pages 6671-6675

  Laufer, Stefan ^a   Hauser, Dominik ^a,b   Stegmiller, Thomas ^a   Bracht, Claudia ^a   Ruff, Kathrin ^a   Schattel, Verena ^a   Albrecht, Wolfgang ^b   Koch, Pierre ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b C a i r Biosciences GmbH   (Germany)

Author keywords

ATP competitive inhibitors; MAP kinase; p38; Pyridinylimidazoles

Indexed keywords

IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CHEMICAL INTERACTION; ENZYME ACTIVITY; MOLECULAR DOCKING; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

IMIDAZOLES; MODELS, MOLECULAR; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77958034430     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.012     Document Type: Article

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