Conversion investigation for lovastatin and its derivatives by HPLC

Journal of Chromatographic Science

Volumn 48, Issue 8, 2010, Pages 631-636

  Huang, Zhibing ^a   Xu, Yang ^a   Li, Yanping ^a   Wang, Yanhua ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 77958003243     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/48.8.631     Document Type: Article

References (18)

1. A. Endo. Lovastatin, a new hypocholesterolemic agent produced by a Monascus spesies. J. Antibiot. 32:852-854 (1979).
2. A. Endo, K. Hasumi, A. Yamada, R. Shimoda, and H. Takeshima. The synthesis of ML-236B (compactin) and monacolin K in fungi. J. Antibiot. 39:1609-1610 (1986).
3. A. W. Alberts. Discovery biochemistry and biology of lovastatin. Am. J. Cardiol. 62:10-15 (1988).
4. R. L. Monaghan, A. W. Alberts, C. H. Hoffmann, and G. Albers-Schonberg. Hypocholesteremic fermentation products and process of preparation. U. S. A. Patent, 4231938 (1980).
5. P. M. Shen, M. S. Shiao, H. R. Dhung, H. R. Lee, Y. S. Chao, and V. M. Hunt. Liquid chromatographic determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. J. Chin. Chem. Soc. 43:451-457 (1996).
6. F. Jozica, Z. Mateja, B. Mojca, C. Aleksa, S. Ales, and R. Ivan. High-performance liquid chromatographic analysis of mevinolin as mevinolinic acid in fermentation broths. J. Chromatogr. A 704:363-367 (1995).
7. Y. G. Li, F. Zhang, Z. T. Wang, and Z. B. Hu. Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry. J Pharm. Biom. Anal. 35:1101-1112 (2004).
8. S. Erturk, A. Onal, and S. M. Cetin. Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples. J. Chromatogr. B 793:193-205 (2003).
9. H. Yang. Y. Feng, and Y. Luan. Determination of simvastatin in. human plasma by liquid chromatography-mass spectrometry. J. Chromatogr. B 785:369-375 (2003).
10. X. S. Miao and C. D. Metcalfe. Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr. A 998:131-141 (2003).
11. M. Jemal, Z. Ouyang, and M. L. Powell. Direct-injection LC-MS-MS method for high-throughput simultaneous quantitation of simvastatin and simvastatin acid in human plasma. J. Pharm. Biomed. Anal. 23:323-340 (2000).
12. J. Ma. Y. Li, Q. Ye, J. Li. Y. Hua, D. Ju, D. Zjang, R. Cooper, and M. Chang. Constituents of red yeast rice, a traditional Chinese food and medicine. J. Agric. Food Chem. 48:5220-5225 (2000).
13. S. J. Rajh, S. Kreft, B. Strukelj, and F. Vrecer. Comparison of CE and HPLC methods for determining lovastatin and its oxidation products after exposure to an oxidative atmosphere. Croatica Chem. Acta 76:263-268 (2003).
14. C. L. Lee, J. J. Wang, and T. M. Pan. Synchronous analysis method for detection of citrinin and the lactone and acid forms of lovastatin in red mold rice. J. AOAC Intern 89:669-677 (2006).
15. A. Alvarez-Lueje, A. Pastine, J. Squella, and L. J. Nunez-Vergara. Assessment of the hydrolytic degradation of lovastatin by HPLC. J. Chilean Chem. Soc. 50:639-646 (2005).
16. L. Y. Ye. P. S. Firby, and M. J. Moore. Determination of lovastatin in human plasma using reverse-phase high-performance liquid chromatography with UV detection. Ther. Drug Monit. 22:737-741 (2000).
17. D. J. Yang and L. S. Hwang. Study on the Conversion of Three Natural Statins from Lactone Forms to Their Corresponding Hydroxy Acid Forms and Their Determination in Pu-Erh Tea. J. Chromatogr. A 1119:277-284 (2006).
18. M. S. Brown, J. R. Faust, J. L. Glodstein, I. Kaneko, and A. Endo. Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. J. Bio. Chem. 253:1121-1128 (1978).