In vitro evaluation of novel sustained release microspheres of glipizide prepared by the emulsion solvent diffusion-evaporation method

Journal of Young Pharmacists

Volumn 2, Issue 1, 2010, Pages 35-41

  Phutane, P ^a   Shidhaye, S ^b   Lotlikar, V ^a   Ghule, A ^a   Sutar, S ^a   Kadam, V ^a  

^a BHARATI VIDYAPEETH S COLLEGE OF PHARMACY   (India)

^b Vivekanand Education Society's College of Pharmacy   (India)

Author keywords

emulsion solvent diffusion evaporation technique; ethyl cellulose; Eudragit S100; Glipizide; Microspheres; sustained release

Indexed keywords

ETHYL CELLULOSE; EUDRAGIT; GLIPIZIDE; MICROSPHERE;

ARTICLE; BIOCOMPATIBILITY; BULK DENSITY; DENSITY; DIFFUSION; DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STRUCTURE; EMULSION; ENCAPSULATION; EVAPORATION; FLOW RATE; IN VITRO STUDY; MORPHOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; SUSTAINED RELEASE FORMULATION;

EID: 77957969934     PISSN: 09751483     EISSN: 09751505     Source Type: Journal    
DOI: 10.4103/0975-1483.62210     Document Type: Article

References (19)

1. Baumgartner S, Kristl J, Vrecer F, Vodopivec P, Zorko B. Optimisation of foating matrix tablets and evaluation of their gastric residence time. Int J Pharm 2000;195:125-35.
2. Khan GM. Controlled release oral dosage forms: Some recent advances in matrix type drug delivery systems. Science 2001;1:350-4.
3. Soppimath KS, Kulkarni AR, Aminabhavi TM. Development of hollow microspheres as foating controlled-release systems for cardiovascular drugs: Preparation and release characteristics. Drug Dev Ind Pharm 2001;27:507-15.
4. Davis SS, Hardy JG, Taylor MJ, Whalley DR, Wilson CG. A comparative study of the gastrointestinal transit of a pellet and tablet formulation. Int J Pharm 1984;21:167-77.
5. nd ed. Vol 1; 1999: G56-9.
6. Verma RK, Garg S. Development and evaluation of osmotically controlled oral drug delivery system of glipizide. Eur J Pharm Biopharm 2004;57:513-25.
7. Chowdary KP, Rao YS. Design and in vitro and in vivo evaluation of mucoadhesive microcapsules of glipizide for oral controlled release: A technical note. AAPS PharmSciTech 2003;4:E39.
8. rd ed. Series-Drugs and Pharmaceutical Sciences. Vol.72. p. 227.
9. rd ed. Indian edition. Mumbai: Varghese Publishing house; 1991. p. 492-521.
10. Jain SK, Awasthi AM, Jain NK, Agrawal GP. Calcium silicate based microspheres of repaglinide for gastroretentive foating drug delivery: Preparation and in vitro characterization. J Control Release 2005;107:300-9.
11. Gidwani SK, Singnurkar P, Tewari PK. Sustained release pharmaceutical composition containing Glipizide and method for producing same. US Patent:62707972001.
12. Kawashima Y, Iwamoto T, Niwa T, Takeuchi H, Hino T Role of the solvent-diffusion-rate modifer in a new emulsion solvent diffusion method for preparation of ketoprofen microspheres. J Microencapsul 1993;10:329-40.
13. Kawashima Y, Niwa T, Takeuchi H, Hino T, Itoh Y Hollow microspheres for use as a foating controlled drug delivery system in the stomach. J Pharm Sci 1992;81:135-40.
14. Lee JH, Park TG, Choi HK. Development of oral drug delivery system using foating microspheres. J Microencapsul 1999;16:715-29.
15. Kawashima Y, Niwa T, Takeuchi H, Hino T, Ito Y Preparation of multiple unit hollow microspheres (microballoons) with acrylic resin containing tranilast and their drug release characteristics (in vitro) and foating behavior (in vivo). J Control Release 1991;16:279-90.
16. rd ed. Vol. 5. New York: Informa healthcare publication; 2006: p.3275-96.
17. Youan BB, Jackson TL, Dickens L, Hernandez C, Owusu-Ababio G. Protein release profles and morphology of biodegradable microcapsules containing an oily core. J Control Release 2001;76:313-26.
18. British Pharmacopoeia. British Pharmacopoeia Commission, London; 2003. Vol. 1.p. 874-5.
19. th ed. Pharmaceutical press; 2009.