Significantly higher percentage of circulating CD27high plasma cells in systemic lupus erythematosus patients with infection than with disease Flare-Up

Yonsei Medical Journal

Volumn 51, Issue 6, 2010, Pages 924-931

  Yang, Deng Ho ^a,b   Chang, Deh Ming ^b   Lai, Jenn Haung ^b   Lin, Fu Huang ^c   Chen, Chen Hung ^b  

^a TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

CD27; Infection; Systemic lupus erythematosus

Indexed keywords

ACICLOVIR; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER; CD27 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; DOUBLE STRANDED DNA ANTIBODY; GANCICLOVIR; TUBERCULOSTATIC AGENT;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIFFERENTIAL DIAGNOSIS; DISEASE ACTIVITY; DISEASE EXACERBATION; FEMALE; FLOW CYTOMETRY; HUMAN; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIOSIS; PLASMA CELL; SYSTEMIC LUPUS ERYTHEMATOSUS; VIRUS INFECTION;

ADULT; ANTIGENS, CD27; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; FEMALE; FLOW CYTOMETRY; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; PLASMA CELLS; VIRUS DISEASES;

EID: 77957964771     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2010.51.6.924     Document Type: Article

References (28)

1. Chan OT, Madaio MP, Shlomchik MJ. The central and multiple roles of B cells in lupus pathogenesis. Immunol Rev 1999;169:107- 21.
2. Lipsky PE. Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity. Nat Immunol 2001;2:764-6.
3. Odendahl M, Jacobi A, Hansen A, Feist E, Hiepe F, Burmester G R, et al. Disturbed peripheral B lymphocyte homeostasis in systemic lupus erythematosus. J Immunol 2000;165:5970-9.
4. Wei C, Anolik J, Cappione A, Zheng B, Pugh-Bernard A, Brooks J, et al. A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. J Immunol 2007;178:6624-33.
5. Jacobi AM, Reiter K, Mackay M, Aranow C, Hiepe F, Radbruch A, et al. Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: delineation by expression of CD27, IgD, and CD95. Arthritis Rheum 2008;58:1762-73.
6. Han BK, White AM, Dao KH, Karp DR, Wakeland EK, Davis LS. Increased prevalence of activated CD70+ CD4+ T cells in the periphery of patients with systemic lupus erythematosus. Lupus 2005;14:598-606.
7. Dolff S, Wilde B, Patschan S, Dürig J, Specker C, Philipp T, et al. Peripheral circulating activated b-cell populations are associated with nephritis and disease activity in patients with systemic lupus erythematosus. Scand J Immunol 2007;66:584-90.
8. Liu CC, Ahearn JM. The search for lupus biomarkers. Best Pract Res Clin Rheumatol 2009;23:507-23.
9. Yang DH, Chang DM, Lai JH, Lin FH, Chen CH. Usefulness of erythrocyte-bound C4d as a biomarker to predict disease activity in patients with systemic lupus erythematosus. Rheumatology (Oxford) 2009;48:1083-7.
10. Jacobi AM, Odendahl M, Reiter K, Bruns A, Burmester GR, Radbruch A, et al. Correlation between circulating CD27 high plasma cells and disease activity in patients with systemic lupus erythematosus. Arthritis Rheum 2003;48:1332-42.
11. Dörner T, Lipsky PE. Correlation of circulating CD27 high plasma cells and disease activity in systemic lupus erythematosus. Lupus 2004;13:283-9.
12. Ten Boekel E, Siegert CE, Vrielink GJ, Van Dam VC, Ceelen A, De Kieviet W. Analyses of CD27++ plasma cells in peripheral blood from patients with bacterial infections and patients with serum antinuclear antibodies. J Clin Immunol 2007;27:467-76.
13. Suh CH, Jeong YS, Park HC, Lee CH, Lee J, Song CH, et al. Risk factors for infection and role of C-reactive protein in Korean patients with systemic lupus erythematosus. Clin Exp Rheumatol 2001;19:191-4.
14. ter Borg EJ, Horst G, Limburg PC, van Rijswijk MH, Kallenberg CG. C-reactive protein levels during disease exacerbations and infections in systemic lupus erythematosus: a prospective longitudinal study. J Rheumatol 1990;17:1642-8.
15. Fritsch RD, Shen X, Illei GG, Yarboro CH, Prussin C, Hathcock KS, et al. Abnormal differentiation of memory T cells in systemic lupus erythematosus. Arthritis Rheum 2006;54:2184-97.
16. Swaak AJ, Hintzen RQ, Huysen V, van den Brink HG, Smeenk JT. Serum levels of soluble forms of T cell activation antigens CD27 and CD25 in systemic lupus erythematosus in relation with lymphocytes count and disease course. Clin Rheumatol 1995;14: 293-300.
17. Font J, Pallares L, Martorell J, Martinez E, Gaya A, Vives J, et al. Elevated soluble CD27 levels in serum of patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1996;81:239- 43.
18. Carter RH. B cells in health and disease. Mayo Clin Proc 2006; 81:377-84.
19. Agematsu K, Hokibara S, Nagumo H, Komiyama A. CD27: a memory B-cell marker. Immunol Today 2000;21:204-6.
20. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients. Medicine (Baltimore) 2003; 82:299-308.
21. Roy S, Tan KT. Pyrexia and normal C-reactive protein (CRP) in patients with systemic lupus erythematosus: always consider the possibility of infection in febrile patients with systemic lupus erythematosus regardless of CRP levels. Rheumatology (Oxford) 2001;40:349-50.
22. Williams RC Jr, Harmon ME, Burlingame R, Du Clos TW. Studies of serum C-reactive protein in systemic lupus erythematosus. J Rheumatol 2005;32:454-61.
23. Hellmich B, Csernok E, de Haas M, von dem Borne AE, Schatz H, Gross WL, et al. Low Fcgamma receptor III and high granulocyte colony-stimulating factor serum levels correlate with the risk of infection in neutropenia due to Felty's syndrome or systemic lupus erythematosus. Am J Med 2002;113:134-9.
24. Egerer K, Feist E, Rohr U, Pruss A, Burmester GR, Dörner T. Increased serum soluble CD14, ICAM-1 and E-selectin correlate with disease activity and prognosis in systemic lupus erythematosus. Lupus 2000;9:614-21.
25. Zandman-Goddard G, Shoenfeld Y. Infections and SLE. Autoimmunity 2005;38:473-85.
26. Bosch X, Guilabert A, Pallarés L, Cerveral R, Ramos-Casals M, Bové A, et al. Infections in systemic lupus erythematosus: a prospective and controlled study of 110 patients. Lupus 2006;15:584-9.
27. Zandman-Goddard G, Shoenfeld Y. SLE and infections. Clin Rev Allergy Immunol 2003;25:29-40.
28. Gladman DD, Hussain F, Ibañez D, Urowitz MB. The nature and outcome of infection in systemic lupus erythematosus. Lupus 2002;11:234-9.