Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells

Cancer Letters

Volumn 298, Issue 2, 2010, Pages 238-249

  Lee, Joo Hyoung ^a,d   Moore, Lakisha D ^b   Kumar, Sanjay ^b   Pritchard, David G ^c   Ponnazhagan, Selvarangan ^b   Deivanayagam, Champion ^d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Breast carcinoma; BTH; Hyaluronan; Hyaluronidase; HylP

Indexed keywords

HYALURONIC ACID; HYALURONIDASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIOPHAGE; BREAST CARCINOMA; CANCER CELL; CELL FUNCTION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; GENE DISRUPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION;

ANIMALS; BACTERIOPHAGES; BREAST NEOPLASMS; CATTLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; HYALURONIC ACID; HYALURONOGLUCOSAMINIDASE; IMMUNOBLOTTING; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUTATION; NEOPLASM INVASIVENESS; OLIGOSACCHARIDES; RHOA GTP-BINDING PROTEIN;

MAMMALIA;

EID: 77957961414     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.07.011     Document Type: Article

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