Structural relationship of sperm soluble hyaluronidase to the sperm membrane protein PH-201

Biology of Reproduction

Volumn 54, Issue 6, 1996, Pages 1343-1349

  Hunnicutt, Gary R ^a   Mahan, Kimberly ^a   Lathrop, William F ^a   Ramarao, Chodavarapu S ^a   Myles, Diana G ^a   Primakoff, Paul ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIDASE; MEMBRANE PROTEIN; SPERM PROTEIN PH 20; UNCLASSIFIED DRUG;

ACROSOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; ENZYME BINDING; GUINEA PIG; MALE; MEMBRANE STRUCTURE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SPERM;

ACROSOME; ANIMALS; ANTIBODIES, MONOCLONAL; CELL ADHESION MOLECULES; CELL MEMBRANE; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUINEA PIGS; HYALURONOGLUCOSAMINIDASE; HYDROGEN-ION CONCENTRATION; IMMUNOBLOTTING; MALE; SPERMATOZOA;

EID: 0029929848     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Suarez S, Katz D, Meizel S. Change in motility that accompany the acrosome reaction in hyperactivated hamster spermatozoa. Gamete Res 1984; 10:253-265.
2. Cummins JM, Yanagimachi R. Development of ability to penetrate the cumulus oophorus by hamster spermatozoa capacitated in vitro, in relation to the timing of the acrosome reaction. Gamete Res 1986; 15:187-212.
3. Talbot P. Sperm penetration through oocyte investments in mammals. Am J Anat 1985; 174:331-346.
4. Drobnis EZ, Katz DF. Videomicroscopy of mammalian fertilization. In: Wassarman PM (ed.), Elements of Mammalian Fertilization. Boca Raton, FL: CRC Press; 1991: 269-300.
5. Bleil JD. Sperm receptors of mammalian eggs. In: Wassarman PM (ed.), Elements of Mammalian Fertilization. Boca Raton, FL: CRC Press; 1991: 133-151
6. Cherr G, Lambert H, Meizel S, Katz D. In vitro studies of the gulden hamster sperm acrosome reaction: completion on the zona pellucida and induction by homologous soluble zonae pellucidae. Dev Biol 1986; 114:119-131.
7. Storey BY, Lee MA, Muller C, Ward CR, Wirtshafter DG. Binding of mouse spermatozoa to the zonae pellucidae of mouse eggs in cumulus: evidence that the acrosomes remain substantially intact. Biol Reprod 1984; 31:1119-1128.
8. Lin Y, Mahan K, Lathrop WF, Myles DG, Primakoff P. A hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg. J Cell Biol 1994; 125:1157-1163.
9. Zhu L, Hope TJ, Hall J, Davies A, Stern M, Muller-Eberhard U, Stern R, Parslow TG. Molecular cloning of a mammalian hyaluronidase reveals identity with hemopexin, a serum heme-binding protein. J Biol Chem 1994; 269:32092-32097.
10. Gmachl M, Kreil G. Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm. Proc Nail Acad Sci USA 1993; 90:3569-3573.
11. Lin Y, Kimmel LH, Myles DG, Primakoff P. Molecular cloning of the human and monkey sperm surface protein PH-20. Proc Nail Acad Sci USA 1993; 90:10071-10075.
12. Lathrop WF, Carmichael EP, Myles DG, Primakoff P. cDNA cloning reveals the molecular structure of a sperm surface protein, PH-20, involved in sperm-egg adhesion and the wide distribution of its gene among mammals. J Cell Biol 1990; 111:2939-2949.
13. Primakoff P, Lathrop W, Woolman L, Cowan A, Myles DG. Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20. Nature 1988; 335:543-546.
14. Primakoff P, Cowan A, Hyatt H, Tredick-Kline J, Myles DG. Purification of the guinea pig sperm PH-20 antigen and detection of a site-specific endoproteolytic activity in sperm preparations that cleaves PH-20 into two disulfide-linked fragments. Biol Reprod 1988; 38:921-934.
15. Primakoff P, Hyatt H, Tredick-Kline J. Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion. J Cell Biol 1987; 104:141-149.
16. Primakoff P, Hyatt H, Myles DG. A role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucida. J Cell Biol 1985; 101:2239-2244.
17. Hoffer AP, Greenberg J. The structure of the epididymis, efferent ductules and ductus deferens of the guinea pig: a light microscope study. Anat Rec 1978; 190:659-678.
18. Dorfman A. Mucopolysaccharidases. Methods Enzymol 1955; 1:166-173.
19. Maniatis T, Fritsch EF, Sambrook J. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory; 1982.
20. Gmachl M, Sagan S, Ketter S, Kreil G. The human sperm protein PH-20 has hyaluronidase activity. FEBS Lett 1993; 336:545-548.
21. Cowan AE, Primakoff P, Myles DG. Sperm exocytosis increases the amount of PH-20 antigen on the surface of guinea pig sperm. J Cell Biol 1986; 103:1289-1297.
22. Gacesa P, Civill ND, Harrison RAP. PH-20 and sperm hyaluronidase: a conceptual conundrum in mammalian fertilization. Biochem J 1994; 303:335-336.
23. Harrison RAP. Hyaluronidase in ram semen: quantitative determination, and isolation of multiple forms. Biochem J 1988; 252:865-874.
24. Myles DG, Hyalt H, Primakoff P. Binding of both acrosome-intact and acrosome-reacted guinea pig sperm to the zona pellucida during in vitro fertilization. Dev Biol 1987; 121:559-567.
25. Yudin AI, Cherr GN, Katz DF. Structure of the cumulus matrix and zona pellucida in the golden hamster: a new view of sperm interaction with oocyte-associated matrices. Cell Tissue Res 1988; 251:555-564.
26. Phelps BM, Myles DG. The guinea pig sperm plasma membrane protein, PH-20, reaches the surface via two transport pathways and becomes localized to a domain after an initial uniform distribution. Dev Biol 1987; 123:63-72.