메뉴 건너뛰기




Volumn 84, Issue 21, 2010, Pages 11563-11568

The carboxy-terminal segment of the human cytomegalovirus DNA polymerase accessory subunit UL44 is crucial for viral replication

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; VIRUS DNA; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; ICP36 PROTEIN, CYTOMEGALOVIRUS; NUCLEAR LOCALIZATION SIGNAL; VIRUS PROTEIN;

EID: 77957959659     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01033-10     Document Type: Article
Times cited : (15)

References (41)
  • 1
    • 0030912888 scopus 로고    scopus 로고
    • The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells
    • Ahn, J. H., and G. S. Hayward. 1997. The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells. J. Virol. 71:4599-4613.
    • (1997) J. Virol. , vol.71 , pp. 4599-4613
    • Ahn, J.H.1    Hayward, G.S.2
  • 2
    • 0032728379 scopus 로고    scopus 로고
    • The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)
    • Ahn, J. H., W. J. Jang, and G. S. Hayward. 1999. The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10). J. Virol. 73:10458-10471.
    • (1999) J. Virol. , vol.73 , pp. 10458-10471
    • Ahn, J.H.1    Jang, W.J.2    Hayward, G.S.3
  • 3
    • 26944433406 scopus 로고    scopus 로고
    • A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus ppUL44
    • DOI 10.1111/j.1600-0854.2005.00331.x
    • Alvisi, G., D. A. Jans, J. Guo, L. A. Pinna, and A. Ripalti. 2005. A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus ppUL44. Traffic 6:1002-1013. (Pubitemid 41472459)
    • (2005) Traffic , vol.6 , Issue.11 , pp. 1002-1013
    • Alvisi, G.1    Jans, D.A.2    Guo, J.3    Pinna, L.A.4    Ripalti, A.5
  • 4
    • 69449102907 scopus 로고    scopus 로고
    • The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells
    • Alvisi, G., D. M. Roth, D. Camozzi, G. S. Pari, A. Loregian, A. Ripalti, and D. A. Jans. 2009. The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells. J. Virol. 83:9567-9576.
    • (2009) J. Virol. , vol.83 , pp. 9567-9576
    • Alvisi, G.1    Roth, D.M.2    Camozzi, D.3    Pari, G.S.4    Loregian, A.5    Ripalti, A.6    Jans, D.A.7
  • 5
    • 33646167477 scopus 로고    scopus 로고
    • Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44
    • Appleton, B. A., J. Brooks, A. Loregian, D. J. Filman, D. M. Coen, and J. M. Hogle. 2006. Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44. J. Biol. Chem. 281:5224-5232.
    • (2006) J. Biol. Chem. , vol.281 , pp. 5224-5232
    • Appleton, B.A.1    Brooks, J.2    Loregian, A.3    Filman, D.J.4    Coen, D.M.5    Hogle, J.M.6
  • 6
    • 3242688965 scopus 로고    scopus 로고
    • The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer
    • Appleton, B. A., A. Loregian, D. J. Filman, D. M. Coen, and J. M. Hogle. 2004. The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer. Mol. Cell 15:233-244.
    • (2004) Mol. Cell , vol.15 , pp. 233-244
    • Appleton, B.A.1    Loregian, A.2    Filman, D.J.3    Coen, D.M.4    Hogle, J.M.5
  • 7
  • 8
    • 0026636556 scopus 로고
    • Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells
    • Ertl, P. F., and K. L. Powell. 1992. Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells. J. Virol. 66:4126-4133.
    • (1992) J. Virol. , vol.66 , pp. 4126-4133
    • Ertl, P.F.1    Powell, K.L.2
  • 9
    • 0027243861 scopus 로고
    • The C-terminal third of UL42, a HSV-1 DNA replication protein, is dispensable for viral growth
    • Gao, M., S. F. DiTusa, and M. G. Cordingley. 1993. The C-terminal third of UL42, a HSV-1 DNA replication protein, is dispensable for viral growth. Virology 194:647-653.
    • (1993) Virology , vol.194 , pp. 647-653
    • Gao, M.1    DiTusa, S.F.2    Cordingley, M.G.3
  • 10
    • 37349058912 scopus 로고    scopus 로고
    • Identification of human cytomegalovirus UL84 virus- And cell-encoded binding partners by using proteomics analysis
    • Gao, Y., K. Colletti, and G. S. Pari. 2008. Identification of human cytomegalovirus UL84 virus- and cell-encoded binding partners by using proteomics analysis. J. Virol. 82:96-104.
    • (2008) J. Virol. , vol.82 , pp. 96-104
    • Gao, Y.1    Colletti, K.2    Pari, G.S.3
  • 11
    • 0021115773 scopus 로고
    • Protein counterparts of human and simian cytomegaloviruses
    • Gibson, W. 1983. Protein counterparts of human and simian cytomegaloviruses. Virology 128:391-406.
    • (1983) Virology , vol.128 , pp. 391-406
    • Gibson, W.1
  • 12
    • 0023239770 scopus 로고
    • Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene
    • Heilbronn, R., G. Jahn, A. Burkle, U. K. Freese, B. Fleckenstein, and H. zur Hausen. 1987. Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene. J. Virol. 61:119-124.
    • (1987) J. Virol. , vol.61 , pp. 119-124
    • Heilbronn, R.1    Jahn, G.2    Burkle, A.3    Freese, U.K.4    Fleckenstein, B.5    Zur Hausen, H.6
  • 13
    • 38849116422 scopus 로고    scopus 로고
    • Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts
    • DOI 10.1128/JVI.01917-07
    • Isomura, H., M. F. Stinski, A. Kudoh, T. Murata, S. Nakayama, Y. Sato, S. Iwahori, and T. Tsurumi. 2008. Noncanonical TATA sequence in the UL44 late promoter of human cytomegalovirus is required for the accumulation of late viral transcripts. J. Virol. 82:1638-1646. (Pubitemid 351206915)
    • (2008) Journal of Virology , vol.82 , Issue.4 , pp. 1638-1646
    • Isomura, H.1    Stinski, M.F.2    Kudoh, A.3    Murata, T.4    Nakayama, S.5    Sato, Y.6    Iwahori, S.7    Tsurumi, T.8
  • 14
    • 34249946519 scopus 로고    scopus 로고
    • The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis
    • Isomura, H., M. F. Stinski, A. Kudoh, S. Nakayama, S. Iwahori, Y. Sato, and T. Tsurumi. 2007. The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis. J. Virol. 81:6197-6206.
    • (2007) J. Virol. , vol.81 , pp. 6197-6206
    • Isomura, H.1    Stinski, M.F.2    Kudoh, A.3    Nakayama, S.4    Iwahori, S.5    Sato, Y.6    Tsurumi, T.7
  • 15
    • 0021269089 scopus 로고
    • Sequence requirements for nuclear location of simian virus 40 large-T antigen
    • Kalderon, D., W. D. Richardson, A. F. Markham, and A. E. Smith. 1984. Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature 311:33-38.
    • (1984) Nature , vol.311 , pp. 33-38
    • Kalderon, D.1    Richardson, W.D.2    Markham, A.F.3    Smith, A.E.4
  • 16
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • Kalderon, D., B. L. Roberts, W. D. Richardson, and A. E. Smith. 1984. A short amino acid sequence able to specify nuclear location. Cell 39:499-509.
    • (1984) Cell , vol.39 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3    Smith, A.E.4
  • 17
    • 0021716296 scopus 로고
    • In vitro mutagenesis of a putative DNA binding domain of SV40 large-T
    • Kalderon, D., and A. E. Smith. 1984. In vitro mutagenesis of a putative DNA binding domain of SV40 large-T. Virology 139:109-137.
    • (1984) Virology , vol.139 , pp. 109-137
    • Kalderon, D.1    Smith, A.E.2
  • 18
    • 0023260898 scopus 로고
    • A cytomegalovirus protein with properties of herpes simplex virus ICP8: Partial purification of the polypeptide and map position of the gene
    • Kemble, G. W., A. L. McCormick, L. Pereira, and E. S. Mocarski. 1987. A cytomegalovirus protein with properties of herpes simplex virus ICP8: partial purification of the polypeptide and map position of the gene. J. Virol. 61:3143-3151.
    • (1987) J. Virol. , vol.61 , pp. 3143-3151
    • Kemble, G.W.1    McCormick, A.L.2    Pereira, L.3    Mocarski, E.S.4
  • 19
    • 77956640441 scopus 로고    scopus 로고
    • Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus
    • Kim, Y.-E., and J.-H. Ahn. 2010. Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus. J. Virol. 84:8409-8421.
    • (2010) J. Virol. , vol.84 , pp. 8409-8421
    • Kim, Y.-E.1    Ahn, J.-H.2
  • 22
    • 0028618183 scopus 로고
    • Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
    • Krishna, T. S., X. P. Kong, S. Gary, P. M. Burgers, and J. Kuriyan. 1994. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA. Cell 79:1233-1243.
    • (1994) Cell , vol.79 , pp. 1233-1243
    • Krishna, T.S.1    Kong, X.P.2    Gary, S.3    Burgers, P.M.4    Kuriyan, J.5
  • 23
    • 0347626042 scopus 로고    scopus 로고
    • Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44
    • Loregian, A., B. A. Appleton, J. M. Hogle, and D. M. Coen. 2004. Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44. J. Virol. 78:158-167.
    • (2004) J. Virol. , vol.78 , pp. 158-167
    • Loregian, A.1    Appleton, B.A.2    Hogle, J.M.3    Coen, D.M.4
  • 24
    • 3242681272 scopus 로고    scopus 로고
    • Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit
    • Loregian, A., B. A. Appleton, J. M. Hogle, and D. M. Coen. 2004. Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein UL44 are crucial for interaction with the UL54 catalytic subunit. J. Virol. 78:9084-9092.
    • (2004) J. Virol. , vol.78 , pp. 9084-9092
    • Loregian, A.1    Appleton, B.A.2    Hogle, J.M.3    Coen, D.M.4
  • 25
    • 34547891497 scopus 로고    scopus 로고
    • Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: Implications for the processivity mechanism
    • Loregian, A., E. Sinigalia, B. Mercorelli, G. Palu, and D. M. Coen. 2007. Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism. Nucleic Acids Res. 35:4779-4791.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4779-4791
    • Loregian, A.1    Sinigalia, E.2    Mercorelli, B.3    Palu, G.4    Coen, D.M.5
  • 26
    • 0028047319 scopus 로고
    • Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemer
    • McVoy, M. A., and S. P. Adler. 1994. Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemer. J. Virol. 68:1040-1051.
    • (1994) J. Virol. , vol.68 , pp. 1040-1051
    • McVoy, M.A.1    Adler, S.P.2
  • 27
    • 0027448623 scopus 로고
    • Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus ori- Lyt-dependent DNA replication
    • Pari, G. S., and D. G. Anders. 1993. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus ori- Lyt-dependent DNA replication. J. Virol. 67:6979-6988.
    • (1993) J. Virol. , vol.67 , pp. 6979-6988
    • Pari, G.S.1    Anders, D.G.2
  • 28
    • 0027417232 scopus 로고
    • Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis
    • Pari, G. S., M. A. Kacica, and D. G. Anders. 1993. Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis. J. Virol. 67:2575-2582.
    • (1993) J. Virol. , vol.67 , pp. 2575-2582
    • Pari, G.S.1    Kacica, M.A.2    Anders, D.G.3
  • 29
    • 0031455909 scopus 로고    scopus 로고
    • Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis
    • Penfold, M. E., and E. S. Mocarski. 1997. Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis. Virology 239:46-61.
    • (1997) Virology , vol.239 , pp. 46-61
    • Penfold, M.E.1    Mocarski, E.S.2
  • 30
    • 23944485244 scopus 로고    scopus 로고
    • Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA
    • Prichard, M. N., H. Lawlor, G. M. Duke, C. Mo, Z. Wang, M. Dixon, G. Kemble, and E. R. Kern. 2005. Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA. Virol. J. 2:55.
    • (2005) Virol. J. , vol.2 , pp. 55
    • Prichard, M.N.1    Lawlor, H.2    Duke, G.M.3    Mo, C.4    Wang, Z.5    Dixon, M.6    Kemble, G.7    Kern, E.R.8
  • 31
    • 47049099550 scopus 로고    scopus 로고
    • Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44)
    • Ranneberg-Nilsen, T., H. A. Dale, L. Luna, R. Slettebakk, O. Sundheim, H. Rollag, and M. Bjoras. 2008. Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44). J. Mol. Biol. 381:276-288.
    • (2008) J. Mol. Biol. , vol.381 , pp. 276-288
    • Ranneberg-Nilsen, T.1    Dale, H.A.2    Luna, L.3    Slettebakk, R.4    Sundheim, O.5    Rollag, H.6    Bjoras, M.7
  • 32
    • 34548159689 scopus 로고    scopus 로고
    • Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro
    • Saffert, R. T., and R. F. Kalejta. 2007. Human cytomegalovirus gene expression is silenced by Daxx-mediated intrinsic immune defense in model latent infections established in vitro. J. Virol. 81:9109-9120.
    • (2007) J. Virol. , vol.81 , pp. 9109-9120
    • Saffert, R.T.1    Kalejta, R.F.2
  • 33
    • 0029817470 scopus 로고    scopus 로고
    • Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays
    • Sarisky, R. T., and G. S. Hayward. 1996. Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays. J. Virol. 70:7398-7413.
    • (1996) J. Virol. , vol.70 , pp. 7398-7413
    • Sarisky, R.T.1    Hayward, G.S.2
  • 34
    • 57349121130 scopus 로고    scopus 로고
    • Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells
    • Sinigalia, E., G. Alvisi, B. Mercorelli, D. M. Coen, G. S. Pari, D. A. Jans, A. Ripalti, G. Palu, and A. Loregian. 2008. Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. J. Virol. 82:12574-12579.
    • (2008) J. Virol. , vol.82 , pp. 12574-12579
    • Sinigalia, E.1    Alvisi, G.2    Mercorelli, B.3    Coen, D.M.4    Pari, G.S.5    Jans, D.A.6    Ripalti, A.7    Palu, G.8    Loregian, A.9
  • 35
    • 75449093392 scopus 로고    scopus 로고
    • Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication
    • Strang, B. L., S. Boulant, and D. M. Coen. 2010. Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication. J. Virol. 84:1771-1784.
    • (2010) J. Virol. , vol.84 , pp. 1771-1784
    • Strang, B.L.1    Boulant, S.2    Coen, D.M.3
  • 36
    • 77956273797 scopus 로고    scopus 로고
    • Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44
    • Strang, B. L., A. P. Geballe, and D. M. Coen. 2010. Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44. J. Gen. Virol. 91:2167-2175.
    • (2010) J. Gen. Virol. , vol.91 , pp. 2167-2175
    • Strang, B.L.1    Geballe, A.P.2    Coen, D.M.3
  • 37
    • 67650863481 scopus 로고    scopus 로고
    • Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84
    • Strang, B. L., E. Sinigalia, L. A. Silva, D. M. Coen, and A. Loregian. 2009. Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84. J. Virol. 83:7581-7589.
    • (2009) J. Virol. , vol.83 , pp. 7581-7589
    • Strang, B.L.1    Sinigalia, E.2    Silva, L.A.3    Coen, D.M.4    Loregian, A.5
  • 38
    • 33645053126 scopus 로고    scopus 로고
    • Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli
    • Tischer, B. K., J. von Einem, B. Kaufer, and N. Osterrieder. 2006. Two-step red-mediated recombination for versatile high-efficiency markerless DNA manipulation in Escherichia coli. Biotechniques 40:191-197.
    • (2006) Biotechniques , vol.40 , pp. 191-197
    • Tischer, B.K.1    Von Einem, J.2    Kaufer, B.3    Osterrieder, N.4
  • 39
    • 0028153248 scopus 로고
    • Functional analysis of human cytomegalovirus polymerase accessory protein
    • Weiland, K. L., N. L. Oien, F. Homa, and M. W. Wathen. 1994. Functional analysis of human cytomegalovirus polymerase accessory protein. Virus Res. 34:191-206.
    • (1994) Virus Res. , vol.34 , pp. 191-206
    • Weiland, K.L.1    Oien, N.L.2    Homa, F.3    Wathen, M.W.4
  • 40
    • 4544355283 scopus 로고    scopus 로고
    • Human cytomegalovirus UL84 insertion mutant defective for viral DNA synthesis and growth
    • Xu, Y., S. A. Cei, A. R. Huete, and G. S. Pari. 2004. Human cytomegalovirus UL84 insertion mutant defective for viral DNA synthesis and growth. J. Virol. 78:10360-10369.
    • (2004) J. Virol. , vol.78 , pp. 10360-10369
    • Xu, Y.1    Cei, S.A.2    Huete, A.R.3    Pari, G.S.4
  • 41
    • 0033867542 scopus 로고    scopus 로고
    • The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase
    • Zuccola, H. J., D. J. Filman, D. M. Coen, and J. M. Hogle. 2000. The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol. Cell 5:267-278.
    • (2000) Mol. Cell , vol.5 , pp. 267-278
    • Zuccola, H.J.1    Filman, D.J.2    Coen, D.M.3    Hogle, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.