메뉴 건너뛰기




Volumn 114, Issue 1, 2010, Pages 17-24

Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Regulation of dopaminergic neural transmission by tyrosine hydroxylase protein at nerve terminals

Author keywords

Dopamine; Dystonia; Striatum; Tetrahydrobiopterin; Tyrosine hydroxylase

Indexed keywords

5 LEVO ERYTHRO 5,6,7,8 TETRAHYDROBIOPTERIN; 6 PYRUVOYLTETRAHYDROPTERIN SYNTHASE; COMPLEMENTARY DNA; DOPAMINE; DOPAMINE BETA MONOOXYGENASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; TETRAHYDROBIOPTERIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

EID: 77957953665     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.09R28FM     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 0034176921 scopus 로고    scopus 로고
    • Tetrahydrobiopterin biosynthesis, regeneration and functions
    • Thöny B, Auerbach G, Blau N. Tetrahydrobiopterin biosynthesis, regeneration and functions. Biochem J. 2000;347:1-16.
    • (2000) Biochem J. , vol.347 , pp. 1-16
    • Thöny, B.1    Auerbach, G.2    Blau, N.3
  • 2
    • 0024351625 scopus 로고
    • Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages
    • Kwon NS, Nathan CF, Stuehr DJ. Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. J Biol Chem. 1989;264:20496-20501.
    • (1989) J Biol Chem. , vol.264 , pp. 20496-20501
    • Kwon, N.S.1    Nathan, C.F.2    Stuehr, D.J.3
  • 3
    • 0024296032 scopus 로고
    • Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
    • Garthwaite J, Charles SL, Chess-Williams R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature. 1988;336:385-388.
    • (1988) Nature , vol.336 , pp. 385-388
    • Garthwaite, J.1    Charles, S.L.2    Chess-Williams, R.3
  • 4
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan C. Nitric oxide and the immune response. Nat Immunol. 2001;2:907-916.
    • (2001) Nat Immunol. , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 5
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • Förstermann U, Münzel T. Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation. 2006;113:1708-1714.
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Förstermann, U.1    Münzel, T.2
  • 7
    • 67349085037 scopus 로고    scopus 로고
    • Disorders of biopterin metabolism
    • Longo N. Disorders of biopterin metabolism. J Inherit Metab Dis. 2009;32:333-342.
    • (2009) J Inherit Metab Dis. , vol.32 , pp. 333-342
    • Longo, N.1
  • 8
    • 0016913614 scopus 로고
    • Hereditary progressive dystonia with marked diurnal fluctuation
    • In:, Eldridge R, Farn S, editors, New York: Raven Press
    • Segawa M, Hosaka A, Miyagawa F, Nomura Y, Imai H. Hereditary progressive dystonia with marked diurnal fluctuation. In: Advances in neurology. Eldridge R, Farn S, editors, Vol. 14, New York: Raven Press; 1976. p. 215-233.
    • (1976) Advances in neurology , vol.14 , pp. 215-233
    • Segawa, M.1    Hosaka, A.2    Miyagawa, F.3    Nomura, Y.4    Imai, H.5
  • 9
    • 0028151448 scopus 로고
    • Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene
    • Ichinose H, Ohye T, Takahashi E, Seki N, Hori T, Segawa M, et al. Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet. 1994;8:236-242.
    • (1994) Nat Genet. , vol.8 , pp. 236-242
    • Ichinose, H.1    Ohye, T.2    Takahashi, E.3    Seki, N.4    Hori, T.5    Segawa, M.6
  • 10
    • 0033595566 scopus 로고    scopus 로고
    • Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia
    • Furukawa Y, Nygaard TG, Gütlich M, Rajput AH, Pifl C, DiStefano L, et al. Striatal biopterin and tyrosine hydroxylase protein reduction in dopa-responsive dystonia. Neurology. 1999;53:1032-1041.
    • (1999) Neurology. , vol.53 , pp. 1032-1041
    • Furukawa, Y.1    Nygaard, T.G.2    Gütlich, M.3    Rajput, A.H.4    Pifl, C.5    di Stefano, L.6
  • 11
    • 0002756708 scopus 로고
    • Tetrahydrobiopterin deficiency: From phenotype to genotype
    • Blau N, Thöny B, Heizmann CW, Dhondt JL. Tetrahydrobiopterin deficiency: From phenotype to genotype. Pteridines. 1993;4:1-10.
    • (1993) Pteridines. , vol.4 , pp. 1-10
    • Blau, N.1    Thöny, B.2    Heizmann, C.W.3    Dhondt, J.L.4
  • 12
    • 0035798563 scopus 로고    scopus 로고
    • Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice
    • Sumi-Ichinose C, Urano F, Kuroda R, Ohye T, Kojima M, Tazawa M, et al. Catecholamines and serotonin are differently regulated by tetrahydrobiopterin. A study from 6-pyruvoyltetrahydropterin synthase knockout mice. J Biol Chem. 2001;276:41150-41160.
    • (2001) J Biol Chem. , vol.276 , pp. 41150-41160
    • Sumi-Ichinose, C.1    Urano, F.2    Kuroda, R.3    Ohye, T.4    Kojima, M.5    Tazawa, M.6
  • 13
    • 0041344529 scopus 로고    scopus 로고
    • Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin
    • Elzaouk L, Leimbacher W, Turri M, Ledermann B, Burki K, Blau N, et al. Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin. J Biol Chem. 2003;278:28303-28311.
    • (2003) J Biol Chem. , vol.278 , pp. 28303-28311
    • Elzaouk, L.1    Leimbacher, W.2    Turri, M.3    Ledermann, B.4    Burki, K.5    Blau, N.6
  • 14
    • 27644540631 scopus 로고    scopus 로고
    • Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and regionspecific monoaminergic abnormalities
    • Sumi-Ichinose C, Urano F, Shimomura A, Sato T, Ikemoto K, Shiraishi H, et al. Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and regionspecific monoaminergic abnormalities. J Neurochem. 2005;95:703-714.
    • (2005) J Neurochem , vol.95 , pp. 703-714
    • Sumi-Ichinose, C.1    Urano, F.2    Shimomura, A.3    Sato, T.4    Ikemoto, K.5    Shiraishi, H.6
  • 15
    • 0026041580 scopus 로고
    • The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice
    • Mercer EH, Hoyle GW, Kapur RP, Brinster RL, Palmiter RD. The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron. 1991;7:703-716.
    • (1991) Neuron , vol.7 , pp. 703-716
    • Mercer, E.H.1    Hoyle, G.W.2    Kapur, R.P.3    Brinster, R.L.4    Palmiter, R.D.5
  • 16
    • 0027996054 scopus 로고
    • Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice
    • Kobayashi K, Morita S, Mizuguchi T, Sawada H, Yamada K, Nagatsu I, et al. Functional and high level expression of human dopamine beta-hydroxylase in transgenic mice. J Biol Chem. 1994;269:29725-29731.
    • (1994) J Biol Chem. , vol.269 , pp. 29725-29731
    • Kobayashi, K.1    Morita, S.2    Mizuguchi, T.3    Sawada, H.4    Yamada, K.5    Nagatsu, I.6
  • 17
    • 50449101430 scopus 로고    scopus 로고
    • Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia
    • Sato K, Sumi-Ichinose C, Kaji R, Ikemoto K, Nomura T, Nagatsu I, et al. Differential involvement of striosome and matrix dopamine systems in a transgenic model of dopa-responsive dystonia. Proc Natl Acad Sci U S A. 2008;105:12551-12556.
    • (2008) Proc Natl Acad Sci U S A. , vol.105 , pp. 12551-12556
    • Sato, K.1    Sumi-Ichinose, C.2    Kaji, R.3    Ikemoto, K.4    Nomura, T.5    Nagatsu, I.6
  • 19
    • 0033724496 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesias and dopamine-dependent stereotypies: A new hypothesis
    • Graybiel AM, Canales JJ, Capper-Loup C. Levodopa-induced dyskinesias and dopamine-dependent stereotypies: a new hypothesis. Trends Neurosci. 2000;23:S71-S77.
    • (2000) Trends Neurosci , vol.23
    • Graybiel, A.M.1    Canales, J.J.2    Capper-Loup, C.3
  • 20
    • 0034069631 scopus 로고    scopus 로고
    • A measure of striatal function predicts motor stereotypy
    • Canales JJ, Graybiel AM. A measure of striatal function predicts motor stereotypy. Nat Neurosci. 2000;3:377-383.
    • (2000) Nat Neurosci. , vol.3 , pp. 377-383
    • Canales, J.J.1    Graybiel, A.M.2
  • 22
    • 0026052489 scopus 로고
    • Conversion of tyrosine hydroxylase to stable and inactive form by the end products
    • Okuno S, Fujisawa H. Conversion of tyrosine hydroxylase to stable and inactive form by the end products. J Neurochem. 1991;57:53-60.
    • (1991) J Neurochem , vol.57 , pp. 53-60
    • Okuno, S.1    Fujisawa, H.2
  • 23
    • 33745653140 scopus 로고    scopus 로고
    • Molecular mechanism for pterin-mediated inactivation of tyrosine hydroxylase: Formation of insoluble aggregates of tyrosine hydroxylase
    • Urano F, Hayashi N, Arisaka F, Kurita H, Murata S, Ichinose H. Molecular mechanism for pterin-mediated inactivation of tyrosine hydroxylase: formation of insoluble aggregates of tyrosine hydroxylase. J Biochem. 2006;139:625-635.
    • (2006) J Biochem. , vol.139 , pp. 625-635
    • Urano, F.1    Hayashi, N.2    Arisaka, F.3    Kurita, H.4    Murata, S.5    Ichinose, H.6
  • 24
    • 0025212130 scopus 로고
    • PH-dependent release of catechlamines from tyrosine hydroxylase and the effect of phosphorylation of Ser40
    • Haavik J, Mmartinez A, Flatmark T. pH-dependent release of catechlamines from tyrosine hydroxylase and the effect of phosphorylation of Ser40. FEBS Lett. 1990;262:363-365.
    • (1990) FEBS Lett. , vol.262 , pp. 363-365
    • Haavik, J.1    Mmartinez, A.2    Flatmark, T.3
  • 25
    • 0030056511 scopus 로고    scopus 로고
    • Teterahydrobiopterin and biogenic amine metabolism in the hph-1 mouse
    • Hyland K, Gunasekera RS, Engle T, Arnold LA. Teterahydrobiopterin and biogenic amine metabolism in the hph-1 mouse. J Neurochem. 1996;67:752-759.
    • (1996) J Neurochem , vol.67 , pp. 752-759
    • Hyland, K.1    Gunasekera, R.S.2    Engle, T.3    Arnold, L.A.4
  • 26
    • 0028897734 scopus 로고
    • Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse
    • Brand MP, Heales SJR, Land JM, Clark JB. Tetrahydrobiopterin deficiency and brain nitric oxide synthase in the hph1 mouse. J Inher Metab Dis. 1995;18:33-39.
    • (1995) J Inher Metab Dis. , vol.18 , pp. 33-39
    • Brand, M.P.1    Heales, S.J.R.2    Land, J.M.3    Clark, J.B.4
  • 28
    • 38649121457 scopus 로고    scopus 로고
    • A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice -as a mouse model for Parkinson's disease
    • Takazawa C, Fujimoto K, Homma D, Sumi-Ichinose C, Nomura T, Ichinose H,et al. A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice -as a mouse model for Parkinson's disease. Biochem Biophys Res Commun. 2008;367:787-792.
    • (2008) Biochem Biophys Res Commun. , vol.367 , pp. 787-792
    • Takazawa, C.1    Fujimoto, K.2    Homma, D.3    Sumi-Ichinose, C.4    Nomura, T.5    Ichinose, H.6
  • 29
    • 0029785475 scopus 로고    scopus 로고
    • Competition for tetrahydrobiopterin between phenylalanine hydroxylase and nitric oxide synthase in rat liver
    • Pastor CM, Williams D, Yoneyama T, Hatakeyama K, Singleton S, Naylor E, et al. Competition for tetrahydrobiopterin between phenylalanine hydroxylase and nitric oxide synthase in rat liver. J Biol Chem. 1996;271:24534-24538.
    • (1996) J Biol Chem. , vol.271 , pp. 24534-24538
    • Pastor, C.M.1    Williams, D.2    Yoneyama, T.3    Hatakeyama, K.4    Singleton, S.5    Naylor, E.6
  • 30
    • 0026448115 scopus 로고
    • "7-Tetrahydrobiopterin," a naturally occurring analogue of tetrahydrobiopterin, is a cofactor for and a potential inhibitor of the aromatic amino acid hydroxylases
    • Davis MD, Ribeiro P, Tipper J, Kaufman S. "7-Tetrahydrobiopterin," a naturally occurring analogue of tetrahydrobiopterin, is a cofactor for and a potential inhibitor of the aromatic amino acid hydroxylases. Proc Natl Acad Sci U S A. 1992;89:10109-10113.
    • (1992) Proc Natl Acad Sci U S A. , vol.89 , pp. 10109-10113
    • Davis, M.D.1    Ribeiro, P.2    Tipper, J.3    Kaufman, S.4
  • 31
    • 0036328426 scopus 로고    scopus 로고
    • Reduced nitric oxide metabolites in CSF of patients with tetrahydrobiopterin deficiency
    • Zorzi G, Thöny B, Blau N. Reduced nitric oxide metabolites in CSF of patients with tetrahydrobiopterin deficiency. J Neurochem. 2002;80:326-364.
    • (2002) J Neurochem , vol.80 , pp. 326-364
    • Zorzi, G.1    Thöny, B.2    Blau, N.3
  • 32
    • 31544481841 scopus 로고    scopus 로고
    • Structure of the blood-brain barrier and its role in the transport of amino acids
    • Hawkins RA, O'Kane RL, Simpson IA, Viña JR. Structure of the blood-brain barrier and its role in the transport of amino acids. J Nutr. 2006;136:218S-226S.
    • (2006) J Nutr. , vol.136
    • Hawkins, R.A.1    O'Kane, R.L.2    Simpson, I.A.3    Viña, J.R.4
  • 33
    • 33646565667 scopus 로고    scopus 로고
    • Effect of metals and phenylalanine on the activity of human tryptophan hydroxylase-2: Comparison with that on tyrosine hydroxylase activity
    • Ogawa S, Ichinose H. Effect of metals and phenylalanine on the activity of human tryptophan hydroxylase-2: Comparison with that on tyrosine hydroxylase activity. Neurosci Lett. 2005;401:261-265.
    • (2005) Neurosci Lett. , vol.401 , pp. 261-265
    • Ogawa, S.1    Ichinose, H.2
  • 34
    • 0025261771 scopus 로고
    • Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments
    • Graybiel AM, Ohta K, Roffler-Tarlov S. Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments. J Neurosci. 1990;10:720-733.
    • (1990) J Neurosci , vol.10 , pp. 720-733
    • Graybiel, A.M.1    Ohta, K.2    Roffler-Tarlov, S.3
  • 35
    • 0003070290 scopus 로고
    • Striatal dopamine in dopa-responsive dystonia: Comparison with idiopathic Parinson's disease and other dopamine- dependent disorders
    • In: Segawa M, Nomura Y, editors, Basel: Karger
    • Hornykiewicz O. Striatal dopamine in dopa-responsive dystonia: comparison with idiopathic Parinson's disease and other dopamine- dependent disorders. In: Segawa M, Nomura Y, editors. Monogr neural science. Basel: Karger; 1995. p. 101-108.
    • (1995) Monogr neural science , pp. 101-108
    • Hornykiewicz, O.1
  • 36
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications
    • Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N Engl J Med. 1988;318:876-880.
    • (1988) N Engl J Med. , vol.318 , pp. 876-880
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 37
    • 0037222117 scopus 로고    scopus 로고
    • Neuronal cell migration for the developmental formation of the mammalian striatum
    • Hamasaki T, Goto S, Nishikawa S, Ushio Y. Neuronal cell migration for the developmental formation of the mammalian striatum. Brain Res Brain Res Rev. 2003;41:1-12.
    • (2003) Brain Res Brain Res Rev. , vol.41 , pp. 1-12
    • Hamasaki, T.1    Goto, S.2    Nishikawa, S.3    Ushio, Y.4
  • 38
    • 0037112019 scopus 로고    scopus 로고
    • Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum
    • Kim DS, Froelick GJ, Palmiter RD. Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. J Neurosci. 2002;22:9841-9849.
    • (2002) J Neurosci , vol.22 , pp. 9841-9849
    • Kim, D.S.1    Froelick, G.J.2    Palmiter, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.