Reduced nitric oxide metabolites in CSF of patients with tetrahydrobiopterin deficiency

Journal of Neurochemistry

Volumn 80, Issue 2, 2002, Pages 362-364

  Zorzi, Giovanna ^a,b   Thöny, Beat ^a   Blau, Nenad ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

6 Pyruvoyl tetrahydropterin; Dihydropteridine; Neurotoxicity; Nitric oxide synthase; Peroxynitrite; Sepiapterin

Indexed keywords

5 HYDROXYTRYPTOPHAN; 6 PYRUVOYLTETRAHYDROPTERIN SYNTHASE; CARBIDOPA; DIHYDROPTERIDINE REDUCTASE; FOLINIC ACID; NITRATE; NITRIC OXIDE; NITRITE; SELEGILINE; SEPIAPTERIN REDUCTASE; TETRAHYDROBIOPTERIN;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; APOPTOSIS; ARTICLE; CELL DAMAGE; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID EXAMINATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; HUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY;

ADOLESCENT; ADULT; ALCOHOL OXIDOREDUCTASES; BIOPTERIN; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITES; PHENYLKETONURIAS; PHOSPHORUS-OXYGEN LYASES;

EID: 0036328426     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-3042.2001.00710.x     Document Type: Article

References (12)

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2. Disorders of tetrahydrobiopterin and related biogenic amines
3. Mutations in the sepiapterin reductase gene cause a novel tetrahydrobiopterin-dependent monoamine neurotransmitter deficiency without hyperphenylalaninemia
4. Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse
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6. Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats
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8. Cerebrospinal fluid nitrite plus nitrate correlates with tetrahydrobiopterin concentration
9. Tetrahydrobiopterin and quinonoid dihydrobiopterin concentrations in CSF from patients with dihydropteridine reductase deficiency
10. Tetrahydropterins but not dihydropterins attenuate the reduction of superoxide from eNOS. A novel role for tetrahydrobiopterin
11. Tetrahydrobiopterin biosynthesis, regeneration, and functions
12. Tetrahydrobiopterin: A critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?