A brain-specific decrease of the tyrosine hydroxylase protein in sepiapterin reductase-null mice-as a mouse model for Parkinson's disease

Biochemical and Biophysical Research Communications

Volumn 367, Issue 4, 2008, Pages 787-792

  Takazawa, Chisato ^a   Fujimoto, Kengo ^b   Homma, Daigo ^a   Sumi Ichinose, Chiho ^c   Nomura, Takahide ^c   Ichinose, Hiroshi ^a   Katoh, Setsuko ^b  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Knock out mouse; NO synthase; Phenylalanine hydroxylase; Sepiapterin reductase; Tetrahydrobiopterin; Tyrosine hydroxylase

Indexed keywords

BRAIN ENZYME; BRAIN PROTEIN; MONOAMINE; NITRIC OXIDE SYNTHASE; PARK3 PROTEIN; PHENYLALANINE 4 MONOOXYGENASE; SEPIAPTERIN REDUCTASE; TETRAHYDROBIOPTERIN; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; GENOTYPE; HETEROZYGOTE; HOMOZYGOSITY; MOUSE; MUTANT; NONHUMAN; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; SYNTHESIS; WEANING; WESTERN BLOTTING;

ALCOHOL OXIDOREDUCTASES; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARKINSON DISEASE; TISSUE DISTRIBUTION; TYROSINE 3-MONOOXYGENASE;

MUS;

EID: 38649121457     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.01.028     Document Type: Article

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