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Volumn 298, Issue 2, 2010, Pages 195-203

Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma

Author keywords

Gemcitabine; MTOR; Non Hodgkin lymphoma; Paclitaxel; RAD001

Indexed keywords

BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; EVEROLIMUS; GEMCITABINE; MAMMALIAN TARGET OF RAPAMYCIN; NAVELBINE; PACLITAXEL; PROTEIN MCL 1;

EID: 77957938917     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.07.005     Document Type: Article
Times cited : (19)

References (32)
  • 1
  • 2
    • 1542618316 scopus 로고    scopus 로고
    • Improving second-line therapy in aggressive non-Hodgkin's lymphoma
    • Gisselbrecht C., Mounier N. Improving second-line therapy in aggressive non-Hodgkin's lymphoma. Semin. Oncol. 2004, 31:12-16.
    • (2004) Semin. Oncol. , vol.31 , pp. 12-16
    • Gisselbrecht, C.1    Mounier, N.2
  • 3
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin D.A., Sabatini D.M. Defining the role of mTOR in cancer. Cancer Cell 2007, 12:9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 5
    • 43049131769 scopus 로고    scopus 로고
    • Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations
    • LoPiccolo J., Blumenthal G.M., Bernstein W.B., Dennis P.A. Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations. Drug Resist. Updates 2008, 11:32-50.
    • (2008) Drug Resist. Updates , vol.11 , pp. 32-50
    • LoPiccolo, J.1    Blumenthal, G.M.2    Bernstein, W.B.3    Dennis, P.A.4
  • 8
    • 33746118057 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
    • Vega F., Medeiros L.J., Leventaki V., Atwell C., Cho-Vega J.H., Tian L., Claret F.-X., Rassidakis G.Z. Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res. 2006, 66:6589-6597.
    • (2006) Cancer Res. , vol.66 , pp. 6589-6597
    • Vega, F.1    Medeiros, L.J.2    Leventaki, V.3    Atwell, C.4    Cho-Vega, J.H.5    Tian, L.6    Claret, F.-X.7    Rassidakis, G.Z.8
  • 11
    • 51449096670 scopus 로고    scopus 로고
    • A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies
    • Rizzieri D.A., Feldman E., DiPersio J.F., Gabrail N., Stock W., Strair R., Rivera V.M., Albitar M., Bedrosian C.L., Giles F.J. A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies. Clin. Cancer Res. 2008, 14:2756-2762.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2756-2762
    • Rizzieri, D.A.1    Feldman, E.2    DiPersio, J.F.3    Gabrail, N.4    Stock, W.5    Strair, R.6    Rivera, V.M.7    Albitar, M.8    Bedrosian, C.L.9    Giles, F.J.10
  • 16
    • 33846516354 scopus 로고    scopus 로고
    • Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma
    • Haritunians T., Mori A., O'Kelly J., Luong Q.T., Giles F.J., Koeffler H.P. Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma. Leukemia 2006, 21:333-339.
    • (2006) Leukemia , vol.21 , pp. 333-339
    • Haritunians, T.1    Mori, A.2    O'Kelly, J.3    Luong, Q.T.4    Giles, F.J.5    Koeffler, H.P.6
  • 18
    • 0036928350 scopus 로고    scopus 로고
    • Rituximab-mediated sensitization of B-non-Hodgkin's lymphoma (NHL) to cytotoxicity induced by paclitaxel, gemcitabine, and vinorelbine
    • Emmanouilides C., Jazirehi A.R., Bonavida B. Rituximab-mediated sensitization of B-non-Hodgkin's lymphoma (NHL) to cytotoxicity induced by paclitaxel, gemcitabine, and vinorelbine. Cancer Biother. Radiopharm. 2002, 17:621-630.
    • (2002) Cancer Biother. Radiopharm. , vol.17 , pp. 621-630
    • Emmanouilides, C.1    Jazirehi, A.R.2    Bonavida, B.3
  • 21
    • 0344577907 scopus 로고    scopus 로고
    • Phase II study of paclitaxel in combination with mitoxantrone and ifosfamide/mesna for patients with relapsed or refractory non-Hodgkin's lymphoma after failure to cytarabine/cisplatin combination
    • Romaguera J.E., Rodriguez M.A., Hagemeister F.B., McLaughlin P., Rodriguez J., Preti A., Younes A., Sarris A.H., Cabanillas F. Phase II study of paclitaxel in combination with mitoxantrone and ifosfamide/mesna for patients with relapsed or refractory non-Hodgkin's lymphoma after failure to cytarabine/cisplatin combination. Invest. New Drugs 1999, 17:187-192.
    • (1999) Invest. New Drugs , vol.17 , pp. 187-192
    • Romaguera, J.E.1    Rodriguez, M.A.2    Hagemeister, F.B.3    McLaughlin, P.4    Rodriguez, J.5    Preti, A.6    Younes, A.7    Sarris, A.H.8    Cabanillas, F.9
  • 23
    • 0030468310 scopus 로고    scopus 로고
    • Activity of single agent vinorelbine in pretreated non-Hodgkin's lymphoma
    • Balzarotti M., Santoro A., Tondini C., Fornier M., Bonadonna G. Activity of single agent vinorelbine in pretreated non-Hodgkin's lymphoma. Ann. Oncol. 1996, 7:970-972.
    • (1996) Ann. Oncol. , vol.7 , pp. 970-972
    • Balzarotti, M.1    Santoro, A.2    Tondini, C.3    Fornier, M.4    Bonadonna, G.5
  • 24
    • 34447338028 scopus 로고    scopus 로고
    • Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21WAF1/CIP1 expression with rapamycin
    • Chiang C.-T., Way T.-D., Lin J.-K. Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21WAF1/CIP1 expression with rapamycin. Mol. Cancer Ther. 2007, 6:2127-2138.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 2127-2138
    • Chiang, C.-T.1    Way, T.-D.2    Lin, J.-K.3
  • 25
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou-Talalay method
    • Chou T.C. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010, 70:440-446.
    • (2010) Cancer Res. , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 26
    • 67649695550 scopus 로고    scopus 로고
    • Gemcitabine-based combination chemotherapy as salvage treatment for refractory or relapsing aggressive non-Hodgkin's lymphoma
    • Yang S.H., Lin Z.Z., Kuo S.H., Cheng A.L. Gemcitabine-based combination chemotherapy as salvage treatment for refractory or relapsing aggressive non-Hodgkin's lymphoma. Am. J. Hematol. 2009, 84:457-459.
    • (2009) Am. J. Hematol. , vol.84 , pp. 457-459
    • Yang, S.H.1    Lin, Z.Z.2    Kuo, S.H.3    Cheng, A.L.4
  • 27
    • 2442464889 scopus 로고    scopus 로고
    • Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks
    • Pommier Y., Sordet O., Antony S., Hayward R.L., Kohn K.W. Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks. Oncogene 2004, 23:2934-2949.
    • (2004) Oncogene , vol.23 , pp. 2934-2949
    • Pommier, Y.1    Sordet, O.2    Antony, S.3    Hayward, R.L.4    Kohn, K.W.5
  • 28
    • 34250330399 scopus 로고    scopus 로고
    • Rapid turnover of mcl-1 couples translation to cell survival and apoptosis
    • Adams K.W., Cooper G.M. Rapid turnover of mcl-1 couples translation to cell survival and apoptosis. J. Biol. Chem. 2007, 282:6192-6200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 6192-6200
    • Adams, K.W.1    Cooper, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.