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Volumn 5, Issue 8, 2010, Pages

EMMPRIN promotes melanoma cells malignant properties through a HIF-2alpha mediated up-regulation of VEGF-receptor-2

Author keywords

[No Author keywords available]

Indexed keywords

CD147 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 2ALPHA; VASCULOTROPIN RECEPTOR 2; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN CONTAINING PROTEIN 1; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; VASCULOTROPIN A;

EID: 77957938278     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012265     Document Type: Article
Times cited : (35)

References (33)
  • 1
    • 67649909568 scopus 로고    scopus 로고
    • Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
    • Hauschild A, Agarwala SS, Trefzer U, Hogg D, Robert C, et al. (2009) Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with carboplatin and paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma. J Clin Oncol 27: 2823-2830.
    • (2009) J Clin Oncol , vol.27 , pp. 2823-2830
    • Hauschild, A.1    Agarwala, S.S.2    Trefzer, U.3    Hogg, D.4    Robert, C.5
  • 2
    • 0030778366 scopus 로고    scopus 로고
    • Transition of horizontal to vertical growth phase melanoma is accompanied by induction of vascular endothelial growth factor expression and angiogenesis
    • Erhard H, Rietveld FJ, van Altena MC, Brocker EB, Ruiter DJ, et al. (1997) Transition of horizontal to vertical growth phase melanoma is accompanied by induction of vascular endothelial growth factor expression and angiogenesis. Melanoma Res 7 Suppl 2: S19-26.
    • (1997) Melanoma Res 7 Suppl , vol.2
    • Erhard, H.1    Rietveld, F.J.2    van Altena, M.C.3    Brocker, E.B.4    Ruiter, D.J.5
  • 3
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • Ferrara N, Gerber HP, LeCouter J (2003) The biology of VEGF and its receptors. Nat Med 9: 669-676.
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 4
    • 61549103137 scopus 로고    scopus 로고
    • Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib
    • Jilaveanu L, Zito C, Lee SJ, Nathanson KL, Camp RL, et al. (2009) Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib. Clin Cancer Res 15: 1076-1085.
    • (2009) Clin Cancer Res , vol.15 , pp. 1076-1085
    • Jilaveanu, L.1    Zito, C.2    Lee, S.J.3    Nathanson, K.L.4    Camp, R.L.5
  • 5
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, Zhang Y, DeCastro R, Guo H, Nakamura T, et al. (1995) The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 55: 434-439.
    • (1995) Cancer Res , vol.55 , pp. 434-439
    • Biswas, C.1    Zhang, Y.2    Decastro, R.3    Guo, H.4    Nakamura, T.5
  • 7
    • 0038127026 scopus 로고    scopus 로고
    • Basigin (CD147): A multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion
    • Muramatsu T, Miyauchi T (2003) Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion. Histol Histopathol 18: 981-987.
    • (2003) Histol Histopathol , vol.18 , pp. 981-987
    • Muramatsu, T.1    Miyauchi, T.2
  • 8
    • 33745075529 scopus 로고    scopus 로고
    • Emmprin (basigin/CD147): Matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression
    • Nabeshima K, Iwasaki H, Koga K, Hojo H, Suzumiya J, et al. (2006) Emmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression. Pathol Int 56: 359-367.
    • (2006) Pathol Int , vol.56 , pp. 359-367
    • Nabeshima, K.1    Iwasaki, H.2    Koga, K.3    Hojo, H.4    Suzumiya, J.5
  • 9
    • 13844296556 scopus 로고    scopus 로고
    • Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression
    • Yan L, Zucker S, Toole BP (2005) Roles of the multifunctional glycoprotein, emmprin (basigin; CD147), in tumour progression. Thromb Haemost 93: 199-204.
    • (2005) Thromb Haemost , vol.93 , pp. 199-204
    • Yan, L.1    Zucker, S.2    Toole, B.P.3
  • 10
    • 33846420208 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion
    • Quemener C, Gabison EE, Naimi B, Lescaille G, Bougatef F, et al. (2007) Extracellular matrix metalloproteinase inducer up-regulates the urokinase-type plasminogen activator system promoting tumor cell invasion. Cancer Res 67: 9-15.
    • (2007) Cancer Res , vol.67 , pp. 9-15
    • Quemener, C.1    Gabison, E.E.2    Naimi, B.3    Lescaille, G.4    Bougatef, F.5
  • 11
    • 34249293335 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
    • Gallagher SM, Castorino JJ, Wang D, Philp NJ (2007) Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. Cancer Res 67: 4182-4189.
    • (2007) Cancer Res , vol.67 , pp. 4182-4189
    • Gallagher, S.M.1    Castorino, J.J.2    Wang, D.3    Philp, N.J.4
  • 12
    • 33845799113 scopus 로고    scopus 로고
    • A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma
    • Chen X, Lin J, Kanekura T, Su J, Lin W, et al. (2006) A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res 66: 11323-11330.
    • (2006) Cancer Res , vol.66 , pp. 11323-11330
    • Chen, X.1    Lin, J.2    Kanekura, T.3    Su, J.4    Lin, W.5
  • 13
    • 0036605095 scopus 로고    scopus 로고
    • Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts
    • Kanekura T, Chen X, Kanzaki T (2002) Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts. Int J Cancer 99: 520-528.
    • (2002) Int J Cancer , vol.99 , pp. 520-528
    • Kanekura, T.1    Chen, X.2    Kanzaki, T.3
  • 14
    • 0030884405 scopus 로고    scopus 로고
    • Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin
    • van den Oord JJ, Paemen L, Opdenakker G, de Wolf-Peeters C (1997) Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin. Am J Pathol 151: 665-670.
    • (1997) Am J Pathol , vol.151 , pp. 665-670
    • van den Oord, J.J.1    Paemen, L.2    Opdenakker, G.3    de Wolf-Peeters, C.4
  • 15
    • 17144422889 scopus 로고    scopus 로고
    • Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases
    • Tang Y, Nakada MT, Kesavan P, McCabe F, Millar H, et al. (2005) Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases. Cancer Res 65: 3193-3199.
    • (2005) Cancer Res , vol.65 , pp. 3193-3199
    • Tang, Y.1    Nakada, M.T.2    Kesavan, P.3    McCabe, F.4    Millar, H.5
  • 16
    • 0642277903 scopus 로고    scopus 로고
    • Emmprin (CD147), a cell surface regulator of matrix metalloproteinase production and function
    • Toole BP (2003) Emmprin (CD147), a cell surface regulator of matrix metalloproteinase production and function. Curr Top Dev Biol 54: 371-389.
    • (2003) Curr Top Dev Biol , vol.54 , pp. 371-389
    • Toole, B.P.1
  • 17
    • 56349095802 scopus 로고    scopus 로고
    • A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis
    • Su J, Chen X, Kanekura T (2009) A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis. Cancer Lett 273: 140-147.
    • (2009) Cancer Lett , vol.273 , pp. 140-147
    • Su, J.1    Chen, X.2    Kanekura, T.3
  • 19
    • 34347205690 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
    • Lee TH, Seng S, Sekine M, Hinton C, Fu Y, et al. (2007) Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med 4: e186.
    • (2007) PLoS Med , vol.4
    • Lee, T.H.1    Seng, S.2    Sekine, M.3    Hinton, C.4    Fu, Y.5
  • 20
    • 0035404270 scopus 로고    scopus 로고
    • Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas
    • Straume O, Akslen LA (2001) Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas. Am J Pathol 159: 223-235.
    • (2001) Am J Pathol , vol.159 , pp. 223-235
    • Straume, O.1    Akslen, L.A.2
  • 21
    • 33644829930 scopus 로고    scopus 로고
    • An autocrine loop directed by the vascular endothelial growth factor promotes invasiveness of human melanoma cells
    • Lacal PM, Ruffini F, Pagani E, D'Atri S (2005) An autocrine loop directed by the vascular endothelial growth factor promotes invasiveness of human melanoma cells. Int J Oncol 27: 1625-1632.
    • (2005) Int J Oncol , vol.27 , pp. 1625-1632
    • Lacal, P.M.1    Ruffini, F.2    Pagani, E.3    D'atri, S.4
  • 22
    • 14844358974 scopus 로고    scopus 로고
    • VEGF and VEGFR-2 immunohistochemistry in human melanocytic naevi and cutaneous melanomas
    • Pisacane AM, Risio M (2005) VEGF and VEGFR-2 immunohistochemistry in human melanocytic naevi and cutaneous melanomas. Melanoma Res 15: 39-43.
    • (2005) Melanoma Res , vol.15 , pp. 39-43
    • Pisacane, A.M.1    Risio, M.2
  • 23
    • 9744253054 scopus 로고    scopus 로고
    • Overproduction of VEGF concomitantly expressed with its receptors promotes growth and survival of melanoma cells through MAPK and PI3K signaling
    • Graells J, Vinyals A, Figueras A, Llorens A, Moreno A, et al. (2004) Overproduction of VEGF concomitantly expressed with its receptors promotes growth and survival of melanoma cells through MAPK and PI3K signaling. J Invest Dermatol 123: 1151-1161.
    • (2004) J Invest Dermatol , vol.123 , pp. 1151-1161
    • Graells, J.1    Vinyals, A.2    Figueras, A.3    Llorens, A.4    Moreno, A.5
  • 24
    • 0029560298 scopus 로고
    • Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF
    • Liu B, Earl HM, Baban D, Shoaibi M, Fabra A, et al. (1995) Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF. Biochem Biophys Res Commun 217: 721-727.
    • (1995) Biochem Biophys Res Commun , vol.217 , pp. 721-727
    • Liu, B.1    Earl, H.M.2    Baban, D.3    Shoaibi, M.4    Fabra, A.5
  • 25
    • 0037470245 scopus 로고    scopus 로고
    • Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1)
    • Elvert G, Kappel A, Heidenreich R, Englmeier U, Lanz S, et al. (2003) Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). J Biol Chem 278: 7520-7530.
    • (2003) J Biol Chem , vol.278 , pp. 7520-7530
    • Elvert, G.1    Kappel, A.2    Heidenreich, R.3    Englmeier, U.4    Lanz, S.5
  • 26
    • 0038788826 scopus 로고    scopus 로고
    • Hypoxiainduced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): Role of cytoplasmic trapping of HIF-2alpha
    • Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, et al. (2003) Hypoxiainduced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha. Mol Cell Biol 23: 4959-4971.
    • (2003) Mol Cell Biol , vol.23 , pp. 4959-4971
    • Park, S.K.1    Dadak, A.M.2    Haase, V.H.3    Fontana, L.4    Giaccia, A.J.5
  • 28
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • Gatenby RA, Gillies RJ (2004) Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899.
    • (2004) Nat Rev Cancer , vol.4 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 29
    • 47749114537 scopus 로고    scopus 로고
    • Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism
    • Baba M, Inoue M, Itoh K, Nishizawa Y (2008) Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism. Biochem Biophys Res Commun 374: 111-116.
    • (2008) Biochem Biophys Res Commun , vol.374 , pp. 111-116
    • Baba, M.1    Inoue, M.2    Itoh, K.3    Nishizawa, Y.4
  • 30
    • 40449105586 scopus 로고    scopus 로고
    • Inhibition of multiple vascular endothelial growth factor receptors (VEGFR) blocks lymph node metastases but inhibition of VEGFR-2 is sufficient to sensitize tumor cells to platinum-based chemotherapeutics
    • Sini P, Samarzija I, Baffert F, Littlewood-Evans A, Schnell C, et al. (2008) Inhibition of multiple vascular endothelial growth factor receptors (VEGFR) blocks lymph node metastases but inhibition of VEGFR-2 is sufficient to sensitize tumor cells to platinum-based chemotherapeutics. Cancer Res 68: 1581-1592.
    • (2008) Cancer Res , vol.68 , pp. 1581-1592
    • Sini, P.1    Samarzija, I.2    Baffert, F.3    Littlewood-Evans, A.4    Schnell, C.5
  • 31
    • 3042551544 scopus 로고    scopus 로고
    • Reproduction of Langerin/CD207 traffic and Birbeck granule formation in a human cell line model
    • McDermott R, Bausinger H, Fricker D, Spehner D, Proamer F, et al. (2004) Reproduction of Langerin/CD207 traffic and Birbeck granule formation in a human cell line model. J Invest Dermatol 123: 72-77.
    • (2004) J Invest Dermatol , vol.123 , pp. 72-77
    • McDermott, R.1    Bausinger, H.2    Fricker, D.3    Spehner, D.4    Proamer, F.5
  • 32
    • 19944414923 scopus 로고    scopus 로고
    • Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: Role in epithelio-stromal interactions and matrix metalloproteinase induction
    • Gabison EE, Mourah S, Steinfels E, Yan L, Hoang-Xuan T, et al. (2005) Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction. Am J Pathol 166: 209-219.
    • (2005) Am J Pathol , vol.166 , pp. 209-219
    • Gabison, E.E.1    Mourah, S.2    Steinfels, E.3    Yan, L.4    Hoang-Xuan, T.5
  • 33
    • 34248389665 scopus 로고    scopus 로고
    • Chemokine-mediated migration of melanoma cells towards lymphatics-a mechanism contributing to metastasis
    • Shields JD, Emmett MS, Dunn DB, Joory KD, Sage LM, et al. (2007) Chemokine-mediated migration of melanoma cells towards lymphatics-a mechanism contributing to metastasis. Oncogene 26: 2997-3005.
    • (2007) Oncogene , vol.26 , pp. 2997-3005
    • Shields, J.D.1    Emmett, M.S.2    Dunn, D.B.3    Joory, K.D.4    Sage, L.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.