Dehydration kinetics of pharmaceutical hydrate: Effects of environmental conditions and crystal forms

Drying Technology

Volumn 28, Issue 10, 2010, Pages 1164-1169

  Khoo, Ji Yi ^a   Williams, Daryl R ^a   Heng, Jerry Y Y ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Acetone; Diffusion; Pharmaceuticals; Sem; Vacuum

Indexed keywords

ACETONE MOLECULES; ACETONE VAPORS; CARBAMAZEPINE; CONTROLLING MECHANISM; CRYSTAL FORMS; DEHYDRATION KINETICS; DIHYDRATES; DRIVING FORCES; DRYING CONDITION; DRYING RATES; ENVIRONMENTAL CONDITIONS; HIGHER TEMPERATURES; LOW VACUUM; MOISTURE REMOVAL; PHARMACEUTICALS; SEM; SOLVENT VAPORS; VACUUM PRESSURE; VARYING TEMPERATURE;

ACETONE; AMIDES; ATMOSPHERIC PRESSURE; CRYSTALS; DEHYDRATION; DEWATERING; DRUG PRODUCTS; HYDRATES; SORPTION; VACUUM; VAPORS;

ATMOSPHERIC TEMPERATURE;

EID: 77957911958     PISSN: 07373937     EISSN: 15322300     Source Type: Journal    
DOI: 10.1080/07373937.2010.482720     Document Type: Article

References (24)

1. Sadikoglu, H.; Ozdemir, M.; Seker, M. Freeze-drying of pharmaceutical products: Research and development needs. Drying Technology 2006, 24 (7), 849-861.
2. Hottot, A.; Andrieu, J.; Vessot, S. Sublimation kinetics during freeze drying of pharmaceutical protein formulation. Drying Technology 2007, 25 (4-6), 753-758.
3. Barresi, A.; Ghio, S.; Fissore, D.; Pisano, R. Freeze drying of pharmaceutical excipients close to collapse temperature: Influence of the process conditions on process time and product quality. Drying Technology 2009, 27 (6), 805-816.
4. Zhang, W.F.; Chen, X.G.; Li, P.W.; Liu, C.S.; He, Q.Z. Preparation and characterization of carboxymethyl chitosan and beta-cyclodextrin microspheres by spray drying. Drying Technology 2008, 26 (1), 108-115.
5. Griesser, U.J. The Importance of Solvates, 1st Ed; Wiley-VCH Verlag GmbH & Co.: Weinheim, 2006; 211-230.
6. Morris, K.R.; Rodriguez-Hornedo, N. Hydrates. In Encyclopedia of Pharmaceutical Technology, 1st Ed; Swarbrick, J., Boylan, J.C., Eds.; Marcel Dekker: New York, 1993; 393-440.
7. Khoo, J.Y.; Heng, J.Y.Y.; Williams, D.R. Pharmaceutical channel hydrate: Elucidation of its thermodynamic stability and solid-state phase transformation to polymorphic anhydrates. AAPS Journal 2009, 11 (S2), 636.
8. Post, R.M.; Ketter, T.A.; Uhde, T.; Ballenger, J.C. Thirty years of clinical experience with carbamazepine in the treatment of bipolar illness-Principles and practice. CNS Drugs 2007, 21 (1), 47-71.
9. Rodriguez-Hornedo, N.; Murphy, D. Surfactant-facilitated crystallization of dihydrate carbamazepine during dissolution of anhydrous polymorph. Journal of Pharmaceutical Sciences 2004, 93 (2), 449-460.
10. Tayel, S.A.; Soliman, I.I.; Louis, D. Improvement of dissolution properties of carbamazepine through application of the liquisolid tablet technique. European Journal of Pharmaceutics and Biopharmaceutics 2008, 69 (1), 342-347.
11. Dugue, J.; Ceolin, R.; Rouland, J.C.; Lepage, F. Polymorphism of carbamazepine: Solid-state on carbamazepine dihydrate. Pharmaceutica Acta Helvetiae 1991, 66 (11), 307-310.
12. Meyer, M.C.; Straughn, A.B.; Jarvi, E.J.; Wood, G.C.; Pelsor, F.R.; Shah, V.P. The bioinequivalence of carbamazepine tablets with a history of clinical failures. Pharmaceutical Research 1992, 9 (12), 1612-1616.
13. Krahn, F.U.; Mielck, J.B. Relations between several polymorphic forms and the dihydrate of carbamazepine. Pharmaceutica Acta Helvetiae 1987, 62 (9), 247-254.
14. Surana, R.; Pyne, A.; Suryanarayanan, R. Solid-vapor interactions: Influence of environmental conditions on the dehydration of carbamazepine dihydrate. AAPS PharmSciTech 2003, 4 (4), 68.
15. Harris, R.K.; Ghi, P.Y.; Puschmann, H.; Apperley, D.C.; Griesser, U.J.; Hammond, R.B.; Ma, C.; Roberts, K.J.; Pearce, G.J.; Yates, J.R.; Pickard, C.J. Structural studies of the polymorphs of carbamazepine, its dihydrate, and two solvates. Organic Process Research and Development 2005, 9 (6), 902-910.
16. Reboul, J.P.; Cristau, B.; Soyfer, J.C. 5H-Dibenz[b,f]azepinecarboxamide-5 (carbamazepine). Acta Crystallographica 1981, B37, 1844-1848.
17. O'Hanlon, J.F. A User's Guide to Vacuum Technology, 2nd Ed; John Wiley & Sons: New York, 1989.
18. Behme, R.J.; Brooke, D. Heat of fusion measurement of a low melting polymorph of carbamazepine that undergoes multiple-phase changes during differential scanning calorimetry analysis. Journal of Pharmaceutical Sciences 1991, 80 (10), 986-990.
19. Li, Y.H.; Han, J.; Zhang, G.G.Z.; Grant, D.J.W.; Suryanarayanan, R. In situ dehydration of carbamazepine dihydrate: A novel technique to prepare amorphous anhydrous carbamazepine. Pharmaceutical Development and Technology 2000, 5 (2), 257-266.
20. Han, J.; Suryanarayanan, R. Influence of environmental conditions on the kinetics and mechanism of dehydration of carbamazepine dihydrate. Pharmaceutical Development and Technology 1998, 3 (4), 587-596.
21. Taylor, T.I.; Taylor, G.G. Vapour pressure and dehydration of unstable salt hydrates, sodium perborate. Industrial & Engineering Chemistry 1935, 27 (6), 672.
22. Terrence, C.F.; Sax, M.; Fromm, G.H.; Chang, B.S.; Yoo, C.S. Effect of baclofen enantiomorphs on the spinal trigeminal nucleus and steric similarities of carbamazepine. Pharmacology 1983, 27 (2), 85-94.
23. Garner, W.E.; Jennings, T.J.J. Nucleation phenomena arising during the dehydration of solid hydrates. Proceedings of the Royal Society of London. Series A, Mathematical and Physical Sciences 1954, 224 (1159), 460-471.
24. Khoo, J.Y.; Heng, J.Y.Y.; Williams, D.R. Agglomeration effects on the drying and dehydration stability of pharmaceutical acicular hydrate: Carbamazepine dihydrate. Industrial & Engineering Chemistry Research 2010, 49 (1), 422-427.