Solid-vapor interactions: Influence of environmental conditions on the dehydration of carbamazepine dihydrate

AAPS PharmSciTech

Volumn 4, Issue 4, 2003, Pages

  Surana, Rahul ^a,b   Pyne, Abira ^a,c   Suryanarayanan, Raj ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b 3M COMPANY   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Carbamazepine; Dehydration; Ethanol vapor; Water vapor

Indexed keywords

ALCOHOL; CARBAMAZEPINE; WATER;

APPARATUS; ARTICLE; CONTROLLED STUDY; DESICCATION; ENVIRONMENTAL FACTOR; HUMIDITY; PHENOMENOLOGY; SOLID; STOICHIOMETRY; VAPOR; WATER LOSS; WATER VAPOR; WEIGHT;

EID: 23144456870     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt040468     Document Type: Article

References (21)

1. Office of the Federal Register. Q6A-Specifications. Test procedures and acceptance criteria for new drugs substances and drug products: Chemical substances. Federal Register. Vol. 62. Washington, DC: Office of the Federal Register; 1997:62889-62910.
2. Han J, Suryanaryanan R. Influence of environmental conditions on the kinetics and mechanisms of dehydration of carbamazepine dihydrate. Pharm Dev Technol. 1998;3(4):587-596.
3. Edwards AD, Shekunov BY, Forbes RT, Grossman JG, York P. Time-resolved x-ray scattering using synchrotron radiation applied to the study of a polymorphic transition in carbamazepine. J Pharm Sci. 2001;90(8):1106-1114.
4. Li Y, Han J, Zhang GGZ, Grant DJW, Suryanarayanan R. In situ dehydration of carbamazepine dehydrate: a novel technique to prepare amorphous anhydrous carbamazepine. Pharm Dev Technol. 2000;5(2):257-266.
5. McMahon LE, Timmins P, Williams AC, York P. Characterization of dihydrates prepared from carbamazepine polymorphs. J Pharm Sci. 1996;85(10)1064-1069.
6. Lang M, Kampf JW, Matzger AJ. For IV of carbamazepine. J Pharm Sci. 2002;91(4)1186-1190.
7. Otsuka M, Hasegawa H, Matsuda Y. Effect of polymorphic transformation during the extrusion-granulation process on the pharmaceutical properties of carbamazepine granules. Chem Pharm Bull. 1997;45(5):894-898.
8. 2O. Cryst Res. Technol.. 1986;21(11):1463-1468.
9. Nyvlt J. On the kinetics of solid-liquid-solid phase tranformation. Cryst Rest Technol. 1997;32(5)695-699.
10. Nordhoff S, Ulrich J. Dehydration of organic and inorganic hydrates by exchange of solvent. Acta Polytechnica Scandinavica, Chemical Technology Series. 1997;244:61-63.
11. Nordhoff S, Ulrich J. Solvent-induced phase transformations of hydrates. J Therm Anal Calorim. 1999;57(1):181-192.
12. Cardew PT, Davey RJ. The kinetics of solvent-mediated phase transformations. P Roy Soc Lond A Mat. 1985;398(1815):415-428.
13. Pikal MJ, Lang JE, Shah S. Desolvation kinetics of cefamandole sodium methanolate: Effect of water vapor. Int J Pharm. 1983;17(2-3):237-262.
14. Han J, Suryanarayanan R. A method of rapid evaluation of the physical stability of pharmaceutical hydrates. Thermochim Acta. 1999;329(2):163-170.
15. Pattern numbers 43-1990 (carbamazepine dihydrate), 43-1998 (anhydrous α-carbamazepine), 33-1565 (anhydrous β-carbamazepine), and 43-1988 (anhydrous γ-carbamazepine). In: PDF-2. Newton Square, PA: International Centre for Diffraction Data; 1998.
16. 2O) in a mixture by powder x-ray diffractometry. Pharm Res. 1989; 6(12):1017-1024.
17. Zografi G. States of water associated with solids. Drug Dev Ind Pharm 1988;14(14):1905-1926.
18. Suryanarayanan R, Mitchell AG. Evaluation of two concepts of crystallinity using calcium gluceptate as a model compound. Ind J Pharm. 1985;24(1):1-17.
19. Saleki-Gerhardt A, Ahlneck C, Zografi G. Assessment of disorder in crystalline solids. Int J Pharm. 1994;10(3)237-247.
20. Surana R, Pyne A, Suryanarayanan R. The influence of water sorption on thermal history of amorphous trehalose. AAPS PharmSci. 2002;4(4). Abstract T2318. Available at: http://www.appspharmsci.org/.
21. Weast RC (Ed.). CRC Handbook of Chemistry and Physics. 50th ed. Cleveland, OH: The Chemical Rubber Co; 1969-1970.