Cadmium regulates copper homoeostasis by inhibiting the activity of Mac1, a transcriptional activator of the copper regulon, in Saccharomyces cerevisiae

Biochemical Journal

Volumn 431, Issue 2, 2010, Pages 257-265

  Heo, Dong Hyuk ^a   Baek, In Joon ^a   Kang, Hyun Jun ^a   Kim, Ji Hyun ^a   Chang, Miwha ^a   Jeong, Mi Young ^a   Kim, Tae Hyoung ^b   Choi, Il Dong ^a   Yun, Cheol Won ^a  

^a Korea University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

Cadmium; Copper; Ctr1; Iron; Mac1; Saccharomyces cerevisiae

Indexed keywords

CADMIUM SALTS; CADMIUM TOXICITY; CDNA MICROARRAYS; CHROMATIN IMMUNOPRECIPITATION; CTR1; HOMOEOSTASIS; IRON UPTAKE; MAC1; MODEL SYSTEM; MOLECULAR LEVELS; MOLECULAR MECHANISM; NORTHERN BLOT ANALYSIS; NORTHERN BLOTTING; SACCHAROMYCES CEREVISIAE; TOXIC METALS; TRANSCRIPTIONAL ACTIVATORS; TRANSCRIPTIONAL LEVELS; WESTERN BLOTTING;

BODY FLUIDS; CADMIUM; COPPER; MAMMALS; PHYSIOLOGY; TOXICITY; TRANSCRIPTION;

YEAST;

CADMIUM; CARRIER PROTEIN; COPPER; COPPER TRANSPORT PROTEIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAC1; UNCLASSIFIED DRUG; IRON; MAC1 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSACTIVATOR PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; COPPER METABOLISM; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; NORTHERN BLOTTING; PRIORITY JOURNAL; REGULON; SACCHAROMYCES CEREVISIAE; UPREGULATION; WESTERN BLOTTING; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FUNGAL GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HOMEOSTASIS; METABOLISM; PROMOTER REGION; PROTEIN BINDING; PROTEIN TRANSPORT;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

CADMIUM; COPPER; DOWN-REGULATION; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; HOMEOSTASIS; IRON; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN TRANSPORT; REGULON; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 77957904667     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100638     Document Type: Article

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