Independent metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae

Eukaryotic Cell

Volumn 4, Issue 11, 2005, Pages 1863-1871

  Keller, Greg ^a   Bird, Amanda ^a   Winge, Dennis R ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; CUP2 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; EPITOPE; HYBRID PROTEIN; MAC1 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CELL NUCLEUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; SACCHAROMYCES CEREVISIAE;

CELL NUCLEUS; COPPER; DNA-BINDING PROTEINS; EPITOPES; GENE EXPRESSION REGULATION, FUNGAL; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

SACCHAROMYCES CEREVISIAE;

EID: 27744494790     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.4.11.1863-1871.2005     Document Type: Article

References (43)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1997. Current Protocols in Molecular Biology, vol. 2. John Wiley & Sons, New York, N.Y.
2. Bloomfield, S. F., G. S. A. B. Stewart, C. E. R. Dodd, I. R. Booth, and E. G. M. Power. 1998. The viable but non-culturable phenomenon explained? Microbiology 144:1-3.
3. Brown, K. R., G. L. Keller, I. J. Pickering, H. H. Harris, G. N. George, and D. R. Winge. 2002. Structures of the cuprous-thiolate clusters of the Mac1 and Ace1 transcriptional activators. Biochemistry 41:6469-6476.
4. Buchman, C., P. Skroch, J. Welch, S. Fogel, and M. Karin. 1989. The CUP2 gene product, regulator of yeast metallothionein expression, is a copper-activated DNA-binding protein. Mol. Cell. Biol. 9:4091-4095.
5. Carroll, M. C., J. B. Girouard, J. L. Ulloa, J. R. Subramaniam, P. C. Wong, J. S. Valentine, and V. C. Culotta. 2004. Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone. Proc. Natl. Acad. Sci. USA 101:5964-5969.
6. Colwell, R. 2000. Viable but nonculturable bacteria: a survival strategy. J. Infect. Chemother. 6:121-125.
7. Cullin, C., and L. Minvielle-Sebastia. 1994. Multipurpose vectors designed for the fast generation of N- or C-terminal epitope-tagged proteins. Yeast 10:105-112.
8. Culotta, V. C., H. D. Joh, S. J. Lin, K. H. Slekar, and J. Strain. 1995. A physiological role for Saccharomyces cerevisiae copper/zinc superoxide dismutase in copper buffering. J. Biol. Chem. 270:29991-29997.
9. Dameron, C. T., D. R. Winge, G. N. George, M. Sansone, S. Hu, and D. Hamer. 1991. A copper-thiolate polynuclear cluster in the ACE1 transcription factor. Proc. Natl. Acad. Sci. USA 88:6127-6131.
10. Dancis, A., D. Haile, D. S. Yuan, and R. D. Klausner. 1994. The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake. J. Biol. Chem. 269:25660-25667.
11. Dancis, A., D. S. Yuan, D. Haile, C. Askwith, D. Eide, C. Moehle, J. Kaplan, and R. D. Klausner. 1994. Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76:393-402.
12. de Winde, J., J. M. Thevelein, and J. Winderickx. 1997. From feast to famine: adaptation to nutrient depletion in yeast, p. 7-52. In S. Hohmann and W. Mager (ed.), Yeast stress responses. Chapman and Hall, New York, N.Y.
13. Dohrmann, P. R., G. Butler, K. Tamai, S. Dorland, J. R. Greene, D. J. Thiele, and D. J. Stillman. 1992. Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev. 6:93-104.
14. Furst, P., and D. Hamer. 1989. Cooperative activation of a eukaryotic transcription factor: interaction between Cu(1) and yeast Ace1 protein. Proc. Natl. Acad. Sci. USA 86:5267-5271.
15. Furst, P., S. Hu, R. Hackett, and D. Hamer. 1988. Copper activates metallothionein gene transcription by altering the conformation of a specific DNA binding protein. Cell 55:705-717.
16. Graden, J. A., M. C. Posewitz, J. R. Simon, G. N. George, I. J. Pickering, and D. R. Winge. 1996. Presence of a copper(I)-thiolate regulatory domain in the copper-activated transcription factor Amt1. Biochemistry 35:14583-14589.
17. Graden, J. A., and D. R. Winge. 1997. Copper-mediated repression of the activation domain in the yeast Mac1p transcription factor. Proc. Natl. Acad. Sci. USA 94:5550-5555.
18. Hassett, R., and D. J. Kosman. 1995. Evidence for Cu(II) reduction as a component of copper uptake by Saccharomyces cerevisiae. J. Biol. Chem. 270:128-134.
19. Heredia, J., M. Crooks, and Z. Zhu. 2001. Phosphorylation and Cu+ coordination-dependent DNA binding of the transcription factor Mac1p in the regulation of copper transport. J. Biol. Chem. 276:8793-8797.
20. Hoa, S. N., H. D. Hunta, R. M. Hortonb, J. K. Pullena, and L. R. Peasea. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
21. Hu, S., P. Furst, and D. Hamer. 1990. The DNA and Cu binding functions of ACE1 are interdigitated within a single domain. New Biol. 2:544-555.
22. Huffman, D. L., and T. V. O'Halloran. 2001. Function, structure, and mechanism of intracellular copper trafficking proteins. Annu. Rev. Biochem. 70:677-701.
23. Jensen, L. T., W. R. Howard, J. J. Strain, D. R. Winge, and V. C. Culotta. 1996. Enhanced effectiveness of copper ion buffering by CUP1 metallothionein compared with CRS5 metallothionein in Saccharomyces cerevisiae. J. Biol. Chem. 271:18514-18519.
24. Jensen, L. T., M. C. Posewitz, C. Srinivasan, and D. R. Winge. 1998. Mapping of the DNA binding domain of the copper-responsive transcription factor Mac1 from Saccharomyces cerevisiae. J. Biol. Chem. 273:23805-23811
25. Jensen, L. T., and D. R. Winge. 1998. Identification of a copper-induced intramolecular interaction in the transcription factor Mac1 from Saccharomyces cerevisiae. EMBO J. 17:5400-5408.
26. Jungmann, J., H. A. Reins, J. Lee, A. Romeo, R. Hassett, D. Kosman, and S. Jentsch. 1993. MAC1, a nuclear regulatory protein related to Cu dependent transcription factors is involved in Cu/Fe utilization and stress resistance in yeast. EMBO J. 12:5051-5056.
27. Keller, G., C. Gross, M. Kelleher, and D. R. Winge. 2000. Functional independence of the two cysteine-rich activation domains in the yeast Mac1 transcription factor. J. Biol. Chem. 275:29193-29199.
28. Knight, S. A. B., S. Labbe, L. F. Kwon, D. J. Kosman, and D. J. Thiele. 1996. A widespread transposable element masks expression of a yeast copper transport gene. Genes Dev. 10:1917-1929.
29. Labbe, S., Z. Zhu, and D. J. Thiele. 1997. Copper-specific transcriptional repression of yeast genes encoding critical components in the copper transport pathway. J. Biol. Chem. 272:15951-15958.
30. Lesuisse, E., M. Casteras-Simon, and P. Labbe. 1996. Evidence for the Saccharomyces cerevisiae ferrireductase system being a multicomponent electron transfer chain. J. Biol. Chem. 271:13578-13583.
31. MacDiarmid, C. W., M. A. Milanick, and D. J. Eide. 2003. Induction of the ZRC1 metal tolerance gene in zinc-limited yeast confers resistance to zinc shock. J. Biol. Chem. 278:15065-15072.
32. Ooi, C. E., E. Rabinovich, A. Dancis, J. S. Bonifacino, and R. D. Klausner. 1996. Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis. EMBO J. 15:3515-3523.
33. Pena, M. M. O., K. Koch, and D. J. Thiele. 1998. Dynamic regulation of copper uptake and detoxification genes in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:2514-2523.
34. Puig, O., F. Caspary, G. Rigaut, B. Rutz, E. Bouveret, E. Bragado-Nilsson, M. Wilm, and B. Seraphin. 2001. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24:218-229.
35. Rees, E. M., J. Lee, and D. J. Thiele. 2004. Mobilization of intracellular copper stores by the Ctr2 vacuolar copper transporter. J. Biol. Chem. 279:54221-54229.
36. Salghetti, S. E., M. Muratani, H. Wijnen, B. Futcher, and W. P. Tansey. 2000. Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis. Proc. Natl. Acad. Sci. USA 97:3118-3123.
37. Serpe, M., A. Joshi, and D. J. Kosman. 1999. Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae. J. Biol. Chem. 274:29211-29219.
38. Szczypka, M., and D. J. Thiele. 1989. A cysteine-rich nuclear protein activates yeast metallothionein gene transcription. Mol. Cell. Biol. 9:421-429.
39. Tanaka, T., D. Knapp, and K. Nasmyth. 1997. Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs. Cell 90:649-660.
40. Thiele, D. J. 1988. ACE1 regulates expression of the Saccharomyces cerevisiae metallothionein gene. Mol. Cell. Biol. 8:2745-2752.
41. Yamaguchi Iwai, Y., M. Serpe, D. Haile, W. Yang, D. J. Kosman, R. D. Klausner, and A. Dancis. 1997. Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1. J. Biol. Chem. 272:17711-17718.
42. Yonkovich, J., R. McKenndry, X. Shi, and Z. Zhu. 2002. Copper ion-sensing transcription factor Mac1p posttranslationally controls the degradation of its target gene product Ctr1p. J. Biol. Chem. 277:23981-23984.
43. Zhu, Z., S. Labbe, M. M. O. Pena, and D. J. Thiele. 1998. Copper differentially regulates the activity and degradation of yeast Mac1 transcription factor. J. Biol. Chem. 273:1277-1280.