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Volumn 45, Issue 8, 2010, Pages 713-721

Purified Canola Lutein Selectively Inhibits Specific Isoforms of Mammalian DNA Polymerases and Reduces Inflammatory Response

Author keywords

Anti inflammation; Canola rapeseed Industrial waste; Carotenoids; DNA polymerase (pol); Enzyme inhibitor; Lutein; Structure and bioactivity relationship

Indexed keywords

ASTAXANTHIN; BETA CAROTENE; BETA CRYPTOXANTHIN; CANTHAXANTHIN; CAPSANTHIN; CAROTENOID; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; DNA DIRECTED DNA POLYMERASE GAMMA; DNA DIRECTED DNA POLYMERASE LAMBDA; DNA POLYMERASE; FUCOXANTHIN; FUCOXANTHINOL; LYCOPENE; PHORBOL 13 ACETATE 12 MYRISTATE; RAPESEED OIL; UNCLASSIFIED DRUG; XANTHOPHYLL; ZEAXANTHIN;

EID: 77957887316     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-010-3449-5     Document Type: Article
Times cited : (13)

References (55)
  • 2
    • 0000368005 scopus 로고
    • Eukaryotic DNA polymerase
    • Freeman WD, New York
    • Kornberg K, Baker TA (1992) Eukaryotic DNA polymerase. In: DNA replication, 2nd edn. Freeman WD, New York, vol 6, pp 197-225
    • (1992) DNA Replication 2nd Edn. , vol.6 , pp. 197-225
    • Kornberg, K.1    Baker, T.A.2
  • 5
    • 10044241865 scopus 로고    scopus 로고
    • Dna repair and replication
    • In: Yang W (ed), Elsevier, San Diego
    • Bebenek K, Kunkel TA (2004) DNA repair and replication. In: Yang W (ed) Advances in protein chemistry. Elsevier, San Diego, vol 69, pp 137-165
    • (2004) Advances in Protein Chemistry , vol.69 , pp. 137-165
    • Bebenek, K.1    Kunkel, T.A.2
  • 6
    • 33747666822 scopus 로고    scopus 로고
    • Human dna polymerase n (poln) is a low fidelity enzyme capable of error-free bypass of 5s-thymine glycol
    • Takata K, Shimizu T, Iwai S, Wood RD (2006) Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J Biol Chem 281:23445-23455
    • (2006) J Biol Chem , vol.281 , pp. 23445-23455
    • Takata, K.1    Shimizu, T.2    Iwai, S.3    Wood, R.D.4
  • 7
    • 0036518628 scopus 로고    scopus 로고
    • Inhibitors of eukaryotic dna polymerases
    • Sakaguchi K, Sugawara F, Mizushina Y (2002) Inhibitors of eukaryotic DNA polymerases. Seikagaku 73:244-251
    • (2002) Seikagaku , vol.73 , pp. 244-251
    • Sakaguchi, K.1    Sugawara, F.2    Mizushina, Y.3
  • 8
    • 67949120329 scopus 로고    scopus 로고
    • Specific inhibitors of mammalian dna polymerase species
    • Mizushina Y (2009) Specific inhibitors of mammalian DNA polymerase species. Biosci Biotechnol Biochem 73:1239-1251
    • (2009) Biosci Biotechnol Biochem , vol.73 , pp. 1239-1251
    • Mizushina, Y.1
  • 9
    • 34447332251 scopus 로고    scopus 로고
    • Fucoxanthin and fucoxanthinol enhance the amount of docosahexaenoic acid in the liver of kkay obese/ diabetic mice
    • Tsukui T, Konno K, Hosokawa M, Maeda H, Sashima T, Miyashita K (2007) Fucoxanthin and fucoxanthinol enhance the amount of docosahexaenoic acid in the liver of KKAy obese/ diabetic mice. J Agric Food Chem 55:5025-5029
    • (2007) J Agric Food Chem , vol.55 , pp. 5025-5029
    • Tsukui, T.1    Konno, K.2    Hosokawa, M.3    Maeda, H.4    Sashima, T.5    Miyashita, K.6
  • 12
    • 0033970827 scopus 로고    scopus 로고
    • The d-loop structure of human mtdna is destabilized directly by 1-methyl-4-phenylpyridinium ion (mpp+), a parkin-sonism-causing toxin
    • Umeda S, Muta T, Ohsato T, Takamatsu C, Hamasaki N, Kang D (2000) The D-loop structure of human mtDNA is destabilized directly by 1-methyl-4- phenylpyridinium ion (MPP+), a parkin-sonism-causing toxin. Eur J Biochem 267:200-208
    • (2000) Eur J Biochem , vol.267 , pp. 200-208
    • Umeda, S.1    Muta, T.2    Ohsato, T.3    Takamatsu, C.4    Hamasaki, N.5    Kang, D.6
  • 13
    • 2642569447 scopus 로고    scopus 로고
    • Subunit protein-affinity isolation of drosophila dna polymerase catalytic subunit
    • Oshige M, Takeuchi R, Ruike R, Kuroda K, Sakaguchi K (2004) Subunit protein-affinity isolation of Drosophila DNA polymerase catalytic subunit. Protein Expr Purif 35:248-256
    • (2004) Protein Expr Purif , vol.35 , pp. 248-256
    • Oshige, M.1    Takeuchi, R.2    Ruike, R.3    Kuroda, K.4    Sakaguchi, K.5
  • 14
    • 0035985037 scopus 로고    scopus 로고
    • Over-expression of Human DNA Polymerase λ in E. Coli and Characterization of the Recombinant Enzyme
    • Shimazaki N, Yoshida K, Kobayashi T, Toji S, Tamai T, Koiwai O (2002) Over-expression of human DNA polymerase λ in E. coli and characterization of the recombinant enzyme. Genes Cells 7:639-651
    • (2002) Genes Cells , vol.7 , pp. 639-651
    • Shimazaki, N.1    Yoshida, K.2    Kobayashi, T.3    Toji, S.4    Tamai, T.5    Koiwai, O.6
  • 15
    • 33747623938 scopus 로고    scopus 로고
    • Synthetic nucleoside and nucleotides. 43. Inhibition of vertebrate telomerases by carbocyclic oxetanocin g (c.oxt-g) triphosphate analogues and influence of c.oxt-g treatment on telomere length in human hl60 cells
    • Yamaguchi T, Saneyoshi M, Takahashi H, Hirokawa S, Amano R, Liu X, Inomata M, Maruyama T (2006) Synthetic Nucleoside and Nucleotides. 43. Inhibition of vertebrate telomerases by carbocyclic oxetanocin G (C.OXT-G) triphosphate analogues and influence of C.OXT-G treatment on telomere length in human HL60 cells. Nucleosides Nucleotides Nucleic Acids 25:539-551
    • (2006) Nucleosides Nucleotides Nucleic Acids , vol.25 , pp. 539-551
    • Yamaguchi, T.1    Saneyoshi, M.2    Takahashi, H.3    Hirokawa, S.4    Amano, R.5    Liu, X.6    Inomata, M.7    Maruyama, T.8
  • 18
    • 0019255946 scopus 로고
    • Chromatin-associated dna polymerase activity in meiotic cells of lily and mouse
    • Sakaguchi K, Hotta Y, Stern H (1980) Chromatin-associated DNA polymerase activity in meiotic cells of lily and mouse. Cell Struct Funct 5:323-334
    • (1980) Cell Struct Funct , vol.5 , pp. 323-334
    • Sakaguchi, K.1    Hotta, Y.2    Stern, H.3
  • 21
    • 0032440708 scopus 로고    scopus 로고
    • Lithocholic acid, a putative tumor promoter, inhibits mammalian dna polymerase β
    • Ogawa A, Murate T, Suzuki M, Nimura Y, Yoshida S (1998) Lithocholic acid, a putative tumor promoter, inhibits mammalian DNA polymerase β. Jpn J Cancer Res 89:1154-1159
    • (1998) Jpn J Cancer Res , vol.89 , pp. 1154-1159
    • Ogawa, A.1    Murate, T.2    Suzuki, M.3    Nimura, Y.4    Yoshida, S.5
  • 23
    • 0021987123 scopus 로고
    • Inhibitory effects of 9-ß-d-xylofuranosyladenine 5'-triphosphate on dna-dependent rna polymerase i and ii from cherry salmon (oncorhynchus masou)
    • Nakayama C, Saneyoshi M (1985) Inhibitory effects of 9-ß-D- xylofuranosyladenine 5'-triphosphate on DNA-dependent RNA polymerase I and II from cherry salmon (Oncorhynchus masou). J Biochem (Tokyo) 97:1385-1389
    • (1985) J Biochem (Tokyo) , vol.97 , pp. 1385-1389
    • Nakayama, C.1    Saneyoshi, M.2
  • 24
    • 0020407164 scopus 로고
    • Isolation and characterization of two mutant forms of t4 polynucleotide kinase
    • Soltis DA, Uhlenbeck OC (1982) Isolation and characterization of two mutant forms of T4 polynucleotide kinase. J Biol Chem 257:11332-11339
    • (1982) J Biol Chem , vol.257 , pp. 11332-11339
    • Soltis, D.A.1    Uhlenbeck, O.C.2
  • 25
    • 0025747944 scopus 로고
    • An endo-exonuclease from meiotic tissues of the basidiomycete coprinus cinereus: Its purification and characterization
    • Lu BC, Sakaguchi K (1991) An endo-exonuclease from meiotic tissues of the basidiomycete Coprinus cinereus: its purification and characterization. J Biol Chem 266:21060-21066
    • (1991) J Biol Chem , vol.266 , pp. 21060-21066
    • Lu, B.C.1    Sakaguchi, K.2
  • 26
    • 0021680940 scopus 로고
    • The mouse ear edema: A quantitatively evaluable assay for tumor promoting compounds and for inhibitors of tumor promotion
    • Gschwendt M, Kittstein W, Furstenberger G, Marks F (1984) The mouse ear edema: a quantitatively evaluable assay for tumor promoting compounds and for inhibitors of tumor promotion. Cancer Lett 25:177-185
    • (1984) Cancer Lett , vol.25 , pp. 177-185
    • Gschwendt, M.1    Kittstein, W.2    Furstenberger, G.3    Marks, F.4
  • 27
    • 77957873763 scopus 로고
    • Beiträge zur chemie der pflanzlichen plastiden. 3. Mitteilung. Über das vorkommen von lutein-3-linolenat in gelben herbstblattern von acer platanoides (l.)
    • Eichenberger W, Grob EC (1963) Beiträge zur Chemie der pflanzlichen Plastiden. 3. Mitteilung. Über das Vorkommen von Lutein-3-linolenat in gelben Herbstblattern von Acer platanoides (L.). Helvetica Chimica Acta 46:2411-2417
    • (1963) Helvetica Chimica Acta , vol.46 , pp. 2411-2417
    • Eichenberger, W.1    Grob, E.C.2
  • 28
    • 4644309094 scopus 로고    scopus 로고
    • Confirmation of the absolute (3r,3's,6'r-configuration of (all-e)-3'-epilutein
    • Molnár P, Deli J, Ösz E, Zsila F, Simonyi M, Tóth G (2004) Confirmation of the absolute (3R,3'S,6'R-configuration of (all-E)-3'-epilutein. Helvetica Chim Acta 87:2159-2168
    • (2004) Helvetica Chim Acta , vol.87 , pp. 2159-2168
    • Molnár, P.1    Deli, J.2    Ösz, E.3    Zsila, F.4    Simonyi, M.5    Tóth, G.6
  • 29
    • 0034705095 scopus 로고    scopus 로고
    • The many faces of dna polymerases: Strategies for mutagenesis and for mutational avoidance
    • Friedberg EC, Feaver WJ, Gerlach VL (2000) The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance. Proc Natl Acad Sci USA 97:5681-5683
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5681-5683
    • Friedberg, E.C.1    Feaver, W.J.2    Gerlach, V.L.3
  • 34
    • 0002547221 scopus 로고
    • Raben Press, NY
    • Hecker E (1978) Carcinogenesis, vol 2. Raben Press, NY, pp 11-48
    • (1978) Carcinogenesis , vol.2 , pp. 11-48
    • Hecker, E.1
  • 36
    • 0032212488 scopus 로고    scopus 로고
    • Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1'-acetoxychavicol acetate
    • Nakamura Y, Murakami A, Ohto Y, Torikai K, Tanaka T, Ohigashi H (1998) Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1'-acetoxychavicol acetate. Cancer Res 58:4832-4839
    • (1998) Cancer Res , vol.58 , pp. 4832-4839
    • Nakamura, Y.1    Murakami, A.2    Ohto, Y.3    Torikai, K.4    Tanaka, T.5    Ohigashi, H.6
  • 38
    • 0027179827 scopus 로고
    • Short gap-filling synthesis by dna polymerase β is processive
    • Singhal RK, Wilson SH (1993) Short gap-filling synthesis by DNA polymerase β is processive. J Biol Chem 268:15906-15911
    • (1993) J Biol Chem , vol.268 , pp. 15906-15911
    • Singhal, R.K.1    Wilson, S.H.2
  • 39
    • 0029028964 scopus 로고
    • Excision of deoxyribose phosphate residues by dna polymerase β during dna repair
    • Matsumoto Y, Kim K (1995) Excision of deoxyribose phosphate residues by DNA polymerase β during DNA repair. Science 269:699-702
    • (1995) Science , vol.269 , pp. 699-702
    • Matsumoto, Y.1    Kim, K.2
  • 41
    • 0037166307 scopus 로고    scopus 로고
    • Dna polymerase From calf thymus preferentially replicates damaged dna
    • Ramadan K, Shevelev IV, Maga G, Hubscher U (2002) DNA polymerase from calf thymus preferentially replicates damaged DNA. J Biol Chem 277:18454-18458
    • (2002) J Biol Chem , vol.277 , pp. 18454-18458
    • Ramadan, K.1    Shevelev, I.V.2    Maga, G.3    Hubscher, U.4
  • 42
    • 0034654379 scopus 로고    scopus 로고
    • Neonatal lethality with abnormal neurogenesis in mice deficient in dna polymerase β
    • Sugo N, Aratani Y, Nagashima Y, Kubota Y, Koyama H (2000) Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase β. EMBO J 19:1397-1404
    • (2000) EMBO J , vol.19 , pp. 1397-1404
    • Sugo, N.1    Aratani, Y.2    Nagashima, Y.3    Kubota, Y.4    Koyama, H.5
  • 43
    • 0035860767 scopus 로고    scopus 로고
    • Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human dna polymerase λ: A possible role in base excision repair
    • Garcia-Diaz M, Bebenek K, Kunkel TA, Blanco L (2001) Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase λ: a possible role in base excision repair. J Biol Chem 276:34659-34663
    • (2001) J Biol Chem , vol.276 , pp. 34659-34663
    • Garcia-Diaz, M.1    Bebenek, K.2    Kunkel, T.A.3    Blanco, L.4
  • 44
    • 0024515691 scopus 로고
    • Difference in the expression level of dna polymerase β among mouse tissues: High expression in the pachytene spermatocyte
    • Hirose F, Hotta Y, Yamaguchi M, Matsukage A (1989) Difference in the expression level of DNA polymerase β among mouse tissues: high expression in the pachytene spermatocyte. Exp Cell Res 181:169-180
    • (1989) Exp Cell Res , vol.181 , pp. 169-180
    • Hirose, F.1    Hotta, Y.2    Yamaguchi, M.3    Matsukage, A.4
  • 47
    • 0032947352 scopus 로고    scopus 로고
    • Beta-carotene, carotenoids and the prevention of coronary heart disease
    • Kritchevsky SB (1999) Beta-carotene, carotenoids and the prevention of coronary heart disease. J Nutr 129:5-8
    • (1999) J Nutr , vol.129 , pp. 5-8
    • Kritchevsky, S.B.1
  • 48
    • 0034149813 scopus 로고    scopus 로고
    • Lutein improves visual function in some patients with retinal degeneration: A pilot study via the internet
    • Dagnelie G, Zorge IS, McDonald TM (2000) Lutein improves visual function in some patients with retinal degeneration: a pilot study via the Internet. Optometry 71:147-164
    • (2000) Optometry , vol.71 , pp. 147-164
    • Dagnelie, G.1    Zorge, I.S.2    McDonald TM3
  • 49
    • 0028021957 scopus 로고
    • Serum antioxidants and myocardial infarction. Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction?
    • Street DA, Comstock GW, Salkeld RM, Schüep W, Klag MJ (1994) Serum antioxidants and myocardial infarction. Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction? Circulation 90:1154-1161
    • (1994) Circulation , vol.90 , pp. 1154-1161
    • Street, D.A.1    Comstock, G.W.2    Salkeld, R.M.3    Schüep, W.4    Klag, M.J.5
  • 50
    • 9644270380 scopus 로고    scopus 로고
    • Diets lower in folic acid and carotenoids are associated with the coronary disease epidemic in central and eastern europe
    • Connor SL, Ojeda LS, Sexton G, Weidner G, Connor WE (2004) Diets lower in folic acid and carotenoids are associated with the coronary disease epidemic in Central and Eastern Europe. J Am Diet Assoc 104:1793-1799
    • (2004) J Am Diet Assoc , vol.104 , pp. 1793-1799
    • Connor, S.L.1    Ojeda, L.S.2    Sexton, G.3    Weidner, G.4    Connor, W.E.5
  • 51
    • 0033564157 scopus 로고    scopus 로고
    • Relation of consumption of vitamin e, vitamin c, and carotenoids to risk for stroke among men in the united states
    • Ascherio A, Rimm EB, Hernan MA, Giovannucci E, Kawachi I, Stampfer MJ, Willett WC (1999) Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States. Ann Int Med 130:963-970
    • (1999) Ann Int Med , vol.130 , pp. 963-970
    • Ascherio, A.1    Rimm, E.B.2    Hernan, M.A.3    Giovannucci, E.4    Kawachi, I.5    Stampfer, M.J.6    Willett, W.C.7
  • 52
    • 0033800904 scopus 로고    scopus 로고
    • Intake of flavonoids, carotenoids, vitamin c and e, and risk of stroke in male smokers
    • Hirvonen T, Virtamo I, Korhonen P, Albanes D, Pietinen P (2000) Intake of flavonoids, carotenoids, vitamin C and E, and risk of stroke in male smokers. Stroke 31:2301-2306
    • (2000) Stroke , vol.31 , pp. 2301-2306
    • Hirvonen, T.1    Virtamo, I.2    Korhonen, P.3    Albanes, D.4    Pietinen, P.5
  • 55
    • 0001651779 scopus 로고
    • Rice hull ash adsorbent performance under commercial soy oil bleaching conditions
    • Proctor A, Clark PK, Parker CA (1995) Rice hull ash adsorbent performance under commercial soy oil bleaching conditions. J Am Oil Chem Soc 72:459-462
    • (1995) J Am Oil Chem Soc , vol.72 , pp. 459-462
    • Proctor, A.1    Clark, P.K.2    Parker, C.A.3


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