-
1
-
-
36849084023
-
Recommendations of the French Society for Rheumatology regarding TNFalpha antagonist therapy in patients with rheumatoid arthritis
-
Fautrel B., Pham T., Mouterde G., et al. Recommendations of the French Society for Rheumatology regarding TNFalpha antagonist therapy in patients with rheumatoid arthritis. Joint Bone Spine 2007, 74:627-637.
-
(2007)
Joint Bone Spine
, vol.74
, pp. 627-637
-
-
Fautrel, B.1
Pham, T.2
Mouterde, G.3
-
2
-
-
70350531479
-
Prospective new biological therapies for rheumatoid arthritis
-
Senolt L., Vencovský J., Pavelka K., et al. Prospective new biological therapies for rheumatoid arthritis. Autoimmun Rev 2009, 9:102-107.
-
(2009)
Autoimmun Rev
, vol.9
, pp. 102-107
-
-
Senolt, L.1
Vencovský, J.2
Pavelka, K.3
-
3
-
-
77957883620
-
Cytokines et voies de signalisation cellulaire au cours de la polyarthrite rhumatoïde
-
Lioté F. Cytokines et voies de signalisation cellulaire au cours de la polyarthrite rhumatoïde. Rev Rhum 2002, 69(Suppl. 5):206-212.
-
(2002)
Rev Rhum
, vol.69
, Issue.SUPPL. 5
, pp. 206-212
-
-
Lioté, F.1
-
4
-
-
10344255627
-
Signal transduction pathways: new targets for treating rheumatoid arthritis
-
Morel J., Berenbaum F. Signal transduction pathways: new targets for treating rheumatoid arthritis. Joint Bone Spine 2004, 71:503-510.
-
(2004)
Joint Bone Spine
, vol.71
, pp. 503-510
-
-
Morel, J.1
Berenbaum, F.2
-
5
-
-
1642555570
-
Histone deacetylase inhibitors in clinical development
-
Rosato R.R., Grant S. Histone deacetylase inhibitors in clinical development. Expert Opin Invest Drugs 2004, 13:21-38.
-
(2004)
Expert Opin Invest Drugs
, vol.13
, pp. 21-38
-
-
Rosato, R.R.1
Grant, S.2
-
6
-
-
13544265432
-
Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?
-
Blanchard F., Chipoy C. Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?. Drug Discov Today 2005, 10:197-204.
-
(2005)
Drug Discov Today
, vol.10
, pp. 197-204
-
-
Blanchard, F.1
Chipoy, C.2
-
7
-
-
34547122494
-
HDAC inhibitors: clinical update and mechanism based potential
-
Glaser K.B. HDAC inhibitors: clinical update and mechanism based potential. Bioch Pharmacol 2007, 74:659-671.
-
(2007)
Bioch Pharmacol
, vol.74
, pp. 659-671
-
-
Glaser, K.B.1
-
9
-
-
60549085246
-
Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HAT on?
-
[Epub 2008 Oct 17]
-
Grabiec A.M., Tak P.P., Reedquist K.A. Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HAT on?. Arthritis Res Ther 2008, 10:226. [Epub 2008 Oct 17].
-
(2008)
Arthritis Res Ther
, vol.10
, pp. 226
-
-
Grabiec, A.M.1
Tak, P.P.2
Reedquist, K.A.3
-
10
-
-
70349464819
-
P21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1
-
Cherrier T., Suzanne S., Redel L., et al. p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1. Oncogene 2009, 28:3380-3389.
-
(2009)
Oncogene
, vol.28
, pp. 3380-3389
-
-
Cherrier, T.1
Suzanne, S.2
Redel, L.3
-
11
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydoxyamic acid SAHA) for refractory cutaneous T cell lymphoma
-
Duvic M., Talpur R., Ni X., et al. Phase 2 trial of oral vorinostat (suberoylanilide hydoxyamic acid SAHA) for refractory cutaneous T cell lymphoma. Blood 2007, 109:31-39.
-
(2007)
Blood
, vol.109
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
-
12
-
-
0035977063
-
Butyrate suppression of colonocyte NFκB activation and cellular proteasome activity
-
Yin L., Laevsky G., Giardina C. Butyrate suppression of colonocyte NFκB activation and cellular proteasome activity. J Biol Chem 2001, 276:44641-44646.
-
(2001)
J Biol Chem
, vol.276
, pp. 44641-44646
-
-
Yin, L.1
Laevsky, G.2
Giardina, C.3
-
13
-
-
0033863238
-
Butyrate inhibits inflammatory response through NFκB inhibition: implications for Crohn's disease
-
Segain J.P., Raingeard de la Blétière D., Bourreille A., et al. Butyrate inhibits inflammatory response through NFκB inhibition: implications for Crohn's disease. Gut 2000, 47:397-403.
-
(2000)
Gut
, vol.47
, pp. 397-403
-
-
Segain, J.P.1
Raingeard de la Blétière, D.2
Bourreille, A.3
-
14
-
-
0034802887
-
The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
-
Ashburner B.P., Westerheide S.D., Bladwin A.S. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 2001, 21:7065-7077.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7065-7077
-
-
Ashburner, B.P.1
Westerheide, S.D.2
Bladwin, A.S.3
-
15
-
-
33744938927
-
Histone deacetylase inhibitors suppress the inducibility of nuclear factor κB by tumor necrosis factor α receptor 1 down regulation
-
Imre G., Gekeler V., Leja A., et al. Histone deacetylase inhibitors suppress the inducibility of nuclear factor κB by tumor necrosis factor α receptor 1 down regulation. Cancer Res 2006, 66:5409-5418.
-
(2006)
Cancer Res
, vol.66
, pp. 5409-5418
-
-
Imre, G.1
Gekeler, V.2
Leja, A.3
-
16
-
-
0344012547
-
Cytoplasmic IkappaBalpha increases NF-kappa B-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3
-
Viatour P., Legrand-Poels S., Van Lint C., et al. Cytoplasmic IkappaBalpha increases NF-kappa B-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3. J Biol Chem 2003, 278:46541-46548.
-
(2003)
J Biol Chem
, vol.278
, pp. 46541-46548
-
-
Viatour, P.1
Legrand-Poels, S.2
Van Lint, C.3
-
17
-
-
4644296075
-
Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression
-
Mahlknecht U., Will J., Hoelzer D., et al. Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression. J Immunol 2004, 173:3979-3990.
-
(2004)
J Immunol
, vol.173
, pp. 3979-3990
-
-
Mahlknecht, U.1
Will, J.2
Hoelzer, D.3
-
18
-
-
0037022598
-
The anti tumor histone deacetylase inhibitor suberoylanilide hydroxyamic acid exhibits anti-inflammatory properties via suppression of cytokines
-
Leoni F., Zaliani A., Bertolini G., et al. The anti tumor histone deacetylase inhibitor suberoylanilide hydroxyamic acid exhibits anti-inflammatory properties via suppression of cytokines. Proc Natl Acad Sci U S A 2002, 99:2995-3000.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2995-3000
-
-
Leoni, F.1
Zaliani, A.2
Bertolini, G.3
-
19
-
-
62849120700
-
Using histone deacetylase inhibitors to enhance Foxp3+ regulatory T cell function and induce allograft tolerance
-
Wang L., Tao R., Hancock W.W. Using histone deacetylase inhibitors to enhance Foxp3+ regulatory T cell function and induce allograft tolerance. Immunol Cell Biol 2009, 87:195-202.
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 195-202
-
-
Wang, L.1
Tao, R.2
Hancock, W.W.3
-
20
-
-
38149020508
-
Epigenetic regulation of established human type 1 versus type 2 cytokine responses
-
Su R.C., Becker A.B., Kozyrskyj A.L., et al. Epigenetic regulation of established human type 1 versus type 2 cytokine responses. J Allergy Clin Immunol 2008, 121:57-63.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 57-63
-
-
Su, R.C.1
Becker, A.B.2
Kozyrskyj, A.L.3
-
21
-
-
33846876336
-
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function
-
Brogdon J.L., Xu Y., Szabo S.J., et al. Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function. Blood 2007, 109:1123-1130.
-
(2007)
Blood
, vol.109
, pp. 1123-1130
-
-
Brogdon, J.L.1
Xu, Y.2
Szabo, S.J.3
-
22
-
-
0037137896
-
Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis
-
Kwon H.Y., Kim M.S., Nakajima H., et al. Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis. Int J Cancer 2002, 97:290-296.
-
(2002)
Int J Cancer
, vol.97
, pp. 290-296
-
-
Kwon, H.Y.1
Kim, M.S.2
Nakajima, H.3
-
23
-
-
31344446119
-
Histone deacetylase 2- mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
-
Ito K., Yamamura S., Essilfie-Quaye S., et al. Histone deacetylase 2- mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression. J Exp Med 2006, 203:7-13.
-
(2006)
J Exp Med
, vol.203
, pp. 7-13
-
-
Ito, K.1
Yamamura, S.2
Essilfie-Quaye, S.3
-
24
-
-
0346873023
-
A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis
-
Chung Y.L., Lee M.Y., Wang A.J., et al. A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis. Mol Ther 2003, 8:707-717.
-
(2003)
Mol Ther
, vol.8
, pp. 707-717
-
-
Chung, Y.L.1
Lee, M.Y.2
Wang, A.J.3
-
25
-
-
27144487343
-
Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-β production
-
Nakamura T., Kukita T., Shobuike T., et al. Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-β production. J Immunol 2005, 175:5809-5816.
-
(2005)
J Immunol
, vol.175
, pp. 5809-5816
-
-
Nakamura, T.1
Kukita, T.2
Shobuike, T.3
-
27
-
-
34047210698
-
Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen induced arthritis in rodents
-
Lin H.S., Hu C.Y., Chan H.Y., et al. Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen induced arthritis in rodents. Br J Pharmacol 2007, 150:862-872.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 862-872
-
-
Lin, H.S.1
Hu, C.Y.2
Chan, H.Y.3
-
28
-
-
44549083450
-
Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody induced arthritis mouse model
-
Nasu Y., Nishida K., Miyazawa S., et al. Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody induced arthritis mouse model. Osteoarthritis Cart 2008, 16:723-732.
-
(2008)
Osteoarthritis Cart
, vol.16
, pp. 723-732
-
-
Nasu, Y.1
Nishida, K.2
Miyazawa, S.3
-
29
-
-
70349385423
-
Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen induced arthritis
-
Saouaf S.J., Li B., Zhang G., et al. Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen induced arthritis. Exp Mol Pathol 2009, 87:99-104.
-
(2009)
Exp Mol Pathol
, vol.87
, pp. 99-104
-
-
Saouaf, S.J.1
Li, B.2
Zhang, G.3
-
30
-
-
34247227700
-
Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid and osteoarthritis patients
-
Huber L., Brock M., Hemmatazad H., et al. Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid and osteoarthritis patients. Arthritis Rheum 2007, 56:1087-1093.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1087-1093
-
-
Huber, L.1
Brock, M.2
Hemmatazad, H.3
-
31
-
-
68849105560
-
Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts
-
Horiuchi M., Morinobu A., Chin T., et al. Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts. J Rheumatol 2009, 36:1580-1589.
-
(2009)
J Rheumatol
, vol.36
, pp. 1580-1589
-
-
Horiuchi, M.1
Morinobu, A.2
Chin, T.3
-
32
-
-
21644471962
-
Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption
-
Young D.A., Lakey R.L., Pennington C.J., et al. Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption. Arthritis Res Ther 2005, 7:R503-R512.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Young, D.A.1
Lakey, R.L.2
Pennington, C.J.3
-
33
-
-
51149086596
-
Histone deacetylase inhibitors suppress interleukin 1β induced nitric oxide and prostaglandin E2 production in human chondrocytes
-
Chabane N., Zayed N., Afif H., et al. Histone deacetylase inhibitors suppress interleukin 1β induced nitric oxide and prostaglandin E2 production in human chondrocytes. Osteoarthritis Cartilage 2008, 16:1267-1274.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 1267-1274
-
-
Chabane, N.1
Zayed, N.2
Afif, H.3
-
34
-
-
34247554311
-
Trichostatin A mediated upregulation of p21(WAF1) contributes to osteoclast apoptosis
-
Yi T., Baek J.H., Kim H.J., et al. Trichostatin A mediated upregulation of p21(WAF1) contributes to osteoclast apoptosis. Exp Mol Med 2007, 39:213-221.
-
(2007)
Exp Mol Med
, vol.39
, pp. 213-221
-
-
Yi, T.1
Baek, J.H.2
Kim, H.J.3
-
35
-
-
3142676314
-
Histone acetylase and deacetylase activity in alveolar macrophages and blood monocytes in asthma
-
Cosio B.G., Mann B., Ito K., et al. Histone acetylase and deacetylase activity in alveolar macrophages and blood monocytes in asthma. Am J Respir Crit Care Med 2004, 170:141-147.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 141-147
-
-
Cosio, B.G.1
Mann, B.2
Ito, K.3
-
36
-
-
33748450692
-
Cigarette smoke-induced Egr-1 upregulates proinflammatory cytokines in pulmonary epithelial cells
-
Reynolds P.R., Cosio M.G., Hoidal J.R. Cigarette smoke-induced Egr-1 upregulates proinflammatory cytokines in pulmonary epithelial cells. Am J Respir Cell Mol Biol 2006, 35:314-319.
-
(2006)
Am J Respir Cell Mol Biol
, vol.35
, pp. 314-319
-
-
Reynolds, P.R.1
Cosio, M.G.2
Hoidal, J.R.3
-
37
-
-
44449126637
-
Histone deacetylase inhibitors: new hope for rheumatoid arthritis?
-
Choo Q.Y., Ho P.C., Lin H.S. Histone deacetylase inhibitors: new hope for rheumatoid arthritis?. Curr Pharm Des 2008, 14:803-820.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 803-820
-
-
Choo, Q.Y.1
Ho, P.C.2
Lin, H.S.3
|