-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, et al. (1994) Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
-
2
-
-
0842324779
-
Obesity wars: Molecular progress confronts an expanding epidemic
-
Flier JS (2004) Obesity wars: molecular progress confronts an expanding epidemic. Cell 116: 337-350.
-
(2004)
Cell
, vol.116
, pp. 337-350
-
-
Flier, J.S.1
-
4
-
-
64349105205
-
Identification and importance of brown adipose tissue in adult humans
-
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, et al. (2009) Identification and importance of brown adipose tissue in adult humans. N Engl J Med 360: 1509-1517.
-
(2009)
N Engl J Med
, vol.360
, pp. 1509-1517
-
-
Cypess, A.M.1
Lehman, S.2
Williams, G.3
Tal, I.4
Rodman, D.5
-
5
-
-
67650242165
-
High incidence of metabolically active brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
-
Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, et al. (2009) High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58: 1526-1531.
-
(2009)
Diabetes
, vol.58
, pp. 1526-1531
-
-
Saito, M.1
Okamatsu-Ogura, Y.2
Matsushita, M.3
Watanabe, K.4
Yoneshiro, T.5
-
6
-
-
0031765344
-
Innervation of mammalian white adipose tissue: Implications for the regulation of total body fat
-
Bartness TJ, Bamshad M (1998) Innervation of mammalian white adipose tissue: implications for the regulation of total body fat. Am J Physiol 275: R1399-1411.
-
(1998)
Am J Physiol
, vol.275
-
-
Bartness, T.J.1
Bamshad, M.2
-
7
-
-
0013983340
-
Application of steady state kinetics to the estimation of synthesis rate and turnover time of tissue catecholamines
-
Brodie BB, Costa E, Dlabac A, Neff NH, Smookler HH (1966) Application of steady state kinetics to the estimation of synthesis rate and turnover time of tissue catecholamines. J Pharmacol Exp Ther 154: 493-498.
-
(1966)
J Pharmacol Exp Ther
, vol.154
, pp. 493-498
-
-
Brodie, B.B.1
Costa, E.2
Dlabac, A.3
Neff, N.H.4
Smookler, H.H.5
-
8
-
-
0346034911
-
Sympathetic control of white adipose tissue in lean and obese humans
-
Dodt C, Lonnroth P, Wellhoner JP, Fehm HL, Elam M (2003) Sympathetic control of white adipose tissue in lean and obese humans. Acta Physiol Scand 177: 351-357.
-
(2003)
Acta Physiol Scand
, vol.177
, pp. 351-357
-
-
Dodt, C.1
Lonnroth, P.2
Wellhoner, J.P.3
Fehm, H.L.4
Elam, M.5
-
9
-
-
0028951399
-
Catecholaminergic innervation of white adipose tissue in Siberian hamsters
-
Youngstrom TG, Bartness TJ (1995) Catecholaminergic innervation of white adipose tissue in Siberian hamsters. Am J Physiol 268: R744-751.
-
(1995)
Am J Physiol
, vol.268
-
-
Youngstrom, T.G.1
Bartness, T.J.2
-
10
-
-
0030581526
-
Effect of acute cold exposure on norepinephrine turnover rates in rat white adipose tissue
-
Garofalo MA, Kettelhut IC, Roselino JE, Migliorini RH (1996) Effect of acute cold exposure on norepinephrine turnover rates in rat white adipose tissue. J Auton Nerv Syst 60: 206-208.
-
(1996)
J Auton Nerv Syst
, vol.60
, pp. 206-208
-
-
Garofalo, M.A.1
Kettelhut, I.C.2
Roselino, J.E.3
Migliorini, R.H.4
-
11
-
-
0030988937
-
Increased sympathetic activity in rat white adipose tissue during prolonged fasting
-
Migliorini RH, Garofalo MA, Kettelhut IC (1997) Increased sympathetic activity in rat white adipose tissue during prolonged fasting. Am J Physiol 272: R656-661.
-
(1997)
Am J Physiol
, vol.272
-
-
Migliorini, R.H.1
Garofalo, M.A.2
Kettelhut, I.C.3
-
12
-
-
0029102059
-
Modulation of obese gene expression in rat brown and white adipose tissues
-
Moinat M, Deng C, Muzzin P, Assimacopoulos-Jeannet F, Seydoux J, et al. (1995) Modulation of obese gene expression in rat brown and white adipose tissues. FEBS Lett 373: 131-134.
-
(1995)
FEBS Lett
, vol.373
, pp. 131-134
-
-
Moinat, M.1
Deng, C.2
Muzzin, P.3
Assimacopoulos-Jeannet, F.4
Seydoux, J.5
-
13
-
-
0030601101
-
Circulating leptin levels are modulated by fasting, cold exposure and insulin administration in lean but not Zucker (fa/fa) rats as measured by ELISA
-
Hardie LJ, Rayner DV, Holmes S, Trayhurn P (1996) Circulating leptin levels are modulated by fasting, cold exposure and insulin administration in lean but not Zucker (fa/fa) rats as measured by ELISA. Biochem Biophys Res Commun 223: 660-665.
-
(1996)
Biochem Biophys Res Commun
, vol.223
, pp. 660-665
-
-
Hardie, L.J.1
Rayner, D.V.2
Holmes, S.3
Trayhurn, P.4
-
14
-
-
0029166158
-
Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice
-
Trayhurn P, Thomas ME, Duncan JS, Rayner DV (1995) Effects of fasting and refeeding on ob gene expression in white adipose tissue of lean and obese (oblob) mice. FEBS Lett 368: 488-490.
-
(1995)
FEBS Lett
, vol.368
, pp. 488-490
-
-
Trayhurn, P.1
Thomas, M.E.2
Duncan, J.S.3
Rayner, D.V.4
-
15
-
-
77957885225
-
-
Bartness TJ, Hypothalamic Paraventricular Nucleus Lesion Involvement in the Sympathetic Control of Lipid Mobilization. Obesity (Silver Spring)
-
Foster MT, Song CK, Bartness TJ (2009) Hypothalamic Paraventricular Nucleus Lesion Involvement in the Sympathetic Control of Lipid Mobilization. Obesity (Silver Spring).
-
(2009)
Song CK
-
-
Foster, M.T.1
-
16
-
-
0014040579
-
Effects of denervation and fasting on white adipose tissue
-
Cantu RC, Goodman HM (1967) Effects of denervation and fasting on white adipose tissue. Am J Physiol 212: 207-212.
-
(1967)
Am J Physiol
, vol.212
, pp. 207-212
-
-
Cantu, R.C.1
Goodman, H.M.2
-
17
-
-
0018075920
-
Ventromedial hypothalamus modulates fat mobilisation during fasting
-
Bray GA, Nishizawa Y (1978) Ventromedial hypothalamus modulates fat mobilisation during fasting. Nature 274: 900-902.
-
(1978)
Nature
, vol.274
, pp. 900-902
-
-
Bray, G.A.1
Nishizawa, Y.2
-
18
-
-
51149096739
-
Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: Neuroanatomical and functional evidence
-
Song CK, Vaughan CH, Keen-Rhinehart E, Harris RB, Richard D, et al. (2008) Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence. Am J Physiol Regul Integr Comp Physiol 295: R417-428.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Song, C.K.1
Vaughan, C.H.2
Keen-Rhinehart, E.3
Harris, R.B.4
Richard, D.5
-
19
-
-
35548962415
-
Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation
-
Brito MN, Brito NA, Baro DJ, Song CK, Bartness TJ (2007) Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation. Endocrinology 148: 5339-5347.
-
(2007)
Endocrinology
, vol.148
, pp. 5339-5347
-
-
Brito, M.N.1
Brito, N.A.2
Baro, D.J.3
Song, C.K.4
Bartness, T.J.5
-
20
-
-
36048955043
-
The central melanocortin system directly controls peripheral lipid metabolism
-
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, et al. (2007) The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest 117: 3475-3488.
-
(2007)
J Clin Invest
, vol.117
, pp. 3475-3488
-
-
Nogueiras, R.1
Wiedmer, P.2
Perez-Tilve, D.3
Veyrat-Durebex, C.4
Keogh, J.M.5
-
21
-
-
34347345996
-
Brain-adipose tissue neural crosstalk
-
Bartness TJ, Song CK (2007) Brain-adipose tissue neural crosstalk. Physiol Behav 91: 343-351.
-
(2007)
Physiol Behav
, vol.91
, pp. 343-351
-
-
Bartness, T.J.1
Song, C.K.2
-
22
-
-
4544357340
-
Learning new tricks from old dogs: Betaadrenergic receptors teach new lessons on firing up adipose tissue metabolism
-
Collins S, Cao W, Robidoux J (2004) Learning new tricks from old dogs: betaadrenergic receptors teach new lessons on firing up adipose tissue metabolism. Mol Endocrinol 18: 2123-2131.
-
(2004)
Mol Endocrinol
, vol.18
, pp. 2123-2131
-
-
Collins, S.1
Cao, W.2
Robidoux, J.3
-
23
-
-
0029887455
-
Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic beta 3-adrenergic agonist
-
Nagase I, Yoshida T, Kumamoto K, Umekawa T, Sakane N, et al. (1996) Expression of uncoupling protein in skeletal muscle and white fat of obese mice treated with thermogenic beta 3-adrenergic agonist. J Clin Invest 97: 2898-2904.
-
(1996)
J Clin Invest
, vol.97
, pp. 2898-2904
-
-
Nagase, I.1
Yoshida, T.2
Kumamoto, K.3
Umekawa, T.4
Sakane, N.5
-
24
-
-
1642464993
-
Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity
-
Jing E, Nillni EA, Sanchez VC, Stuart RC, Good DJ (2004) Deletion of the Nhlh2 transcription factor decreases the levels of the anorexigenic peptides alpha melanocyte-stimulating hormone and thyrotropin-releasing hormone and implicates prohormone convertases I and II in obesity. Endocrinology 145: 1503-1513.
-
(2004)
Endocrinology
, vol.145
, pp. 1503-1513
-
-
Jing, E.1
Nillni, E.A.2
Sanchez, V.C.3
Stuart, R.C.4
Good, D.J.5
-
25
-
-
77957870580
-
-
(2010) pp. Allen Institute for Brain Science
-
(2010) pp. Allen Institute for Brain Science.
-
-
-
-
26
-
-
44649197895
-
Nescient helix-loop-helix 2 interacts with signal transducer and activator of transcription 3 to regulate transcription of prohormone convertase 1/3
-
Fox DL, Good DJ (2008) Nescient helix-loop-helix 2 interacts with signal transducer and activator of transcription 3 to regulate transcription of prohormone convertase 1/3. Mol Endocrinol 22: 1438-1448.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1438-1448
-
-
Fox, D.L.1
Good, D.J.2
-
27
-
-
0030960861
-
Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene
-
Good DJ, Porter FD, Mahon KA, Parlow AF, Westphal H, et al. (1997) Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet 15: 397-401.
-
(1997)
Nat Genet
, vol.15
, pp. 397-401
-
-
Good, D.J.1
Porter, F.D.2
Mahon, K.A.3
Parlow, A.F.4
Westphal, H.5
-
28
-
-
58149173432
-
Nhlh2: A basic helix-loop-helix transcription factor controlling physical activity
-
Good DJ, Coyle CA, Fox DL (2008) Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity. Exerc Sport Sci Rev 36: 187-192.
-
(2008)
Exerc Sport Sci Rev
, vol.36
, pp. 187-192
-
-
Good, D.J.1
Coyle, C.A.2
Fox, D.L.3
-
30
-
-
0032065645
-
Clinical review 94: What's in a name? Search of Leptin's Physiologic Role
-
Flier JS (1998) Clinical review 94: What's in a name? In search of leptin's physiologic role. J Clin Endocrinol Metab 83: 1407-1413.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 1407-1413
-
-
Flier, J.S.1
-
31
-
-
58149187911
-
Norepinephrine controls both torpor initiation and emergence via distinct mechanisms in the mouse
-
Swoap SJ, Weinshenker D (2008) Norepinephrine controls both torpor initiation and emergence via distinct mechanisms in the mouse. PLoS One 3: e4038.
-
(2008)
PLoS One
, vol.3
-
-
Swoap, S.J.1
Weinshenker, D.2
-
32
-
-
0036853701
-
Reduced voluntary activity precedes adult-onset obesity in Nhlh2 knockout mice
-
Coyle CA, Jing E, Hosmer T, Powers JB, Wade G, et al. (2002) Reduced voluntary activity precedes adult-onset obesity in Nhlh2 knockout mice. Physiol Behav 77: 387-402.
-
(2002)
Physiol Behav
, vol.77
, pp. 387-402
-
-
Coyle, C.A.1
Jing, E.2
Hosmer, T.3
Powers, J.B.4
Wade, G.5
-
33
-
-
0038064168
-
Strain variation in the response of body temperature to dietary restriction
-
Rikke BA, Yerg JE, 3rd, Battaglia ME, Nagy TR, Allison DB, et al. (2003) Strain variation in the response of body temperature to dietary restriction. Mech Ageing Dev 124: 663-678.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 663-678
-
-
Rikke, B.A.1
Yerg III, J.E.2
Battaglia, M.E.3
Nagy, T.R.4
Allison, D.B.5
-
34
-
-
34547470482
-
Expression of the hypothalamic transcription factor Nhlh2 is dependent on energy availability
-
Vella KR, Burnside AS, Brennan KM, Good DJ (2007) Expression of the hypothalamic transcription factor Nhlh2 is dependent on energy availability. J Neuroendocrinol 19: 499-510.
-
(2007)
J Neuroendocrinol
, vol.19
, pp. 499-510
-
-
Vella, K.R.1
Burnside, A.S.2
Brennan, K.M.3
Good, D.J.4
-
35
-
-
0031792072
-
White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number
-
Youngstrom TG, Bartness TJ (1998) White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number. Am J Physiol 275: R1488-1493.
-
(1998)
Am J Physiol
, vol.275
-
-
Youngstrom, T.G.1
Bartness, T.J.2
-
36
-
-
65849170089
-
Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice
-
Ruschke K, Ebelt H, Kloting N, Boettger T, Raum K, et al. (2009) Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice. PLoS One 4: e5516.
-
(2009)
PLoS One
, vol.4
-
-
Ruschke, K.1
Ebelt, H.2
Kloting, N.3
Boettger, T.4
Raum, K.5
-
37
-
-
30644476808
-
The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling
-
Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D (2006) The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling. J Neurosci 26: 241-245.
-
(2006)
J Neurosci
, vol.26
, pp. 241-245
-
-
Swoap, S.J.1
Gutilla, M.J.2
Liles, L.C.3
Smith, R.O.4
Weinshenker, D.5
-
38
-
-
0026023396
-
Role of sympathetic nerves in effects of estradiol on rat white adipose tissue
-
Lazzarini SJ, Wade GN (1991) Role of sympathetic nerves in effects of estradiol on rat white adipose tissue. Am J Physiol 260: R47-51.
-
(1991)
Am J Physiol
, vol.260
-
-
Lazzarini, S.J.1
Wade, G.N.2
-
39
-
-
84891381363
-
Obese Mouse Models
-
In: Conn PM, ed., TotowaNew Jersey: Humana
-
Good DJ (2007) Obese Mouse Models. In: Conn PM, ed. Sourcebook of Models for Biomedical Research. TotowaNew Jersey: Humana. pp 683-702.
-
(2007)
Sourcebook of Models For Biomedical Research
, pp. 683-702
-
-
Good, D.J.1
-
40
-
-
0031843809
-
Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue
-
Bamshad M, Aoki VT, Adkison MG, Warren WS, Bartness TJ (1998) Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue. Am J Physiol 275: R291-299.
-
(1998)
Am J Physiol
, vol.275
-
-
Bamshad, M.1
Aoki, V.T.2
Adkison, M.G.3
Warren, W.S.4
Bartness, T.J.5
-
41
-
-
0033036199
-
CNS origins of the sympathetic nervous system outflow to brown adipose tissue
-
Bamshad M, Song CK, Bartness TJ (1999) CNS origins of the sympathetic nervous system outflow to brown adipose tissue. Am J Physiol 276: R1569-1578.
-
(1999)
Am J Physiol
, vol.276
-
-
Bamshad, M.1
Song, C.K.2
Bartness, T.J.3
-
42
-
-
0029813768
-
The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes
-
Gettys TW, Harkness PJ, Watson PM (1996) The beta 3-adrenergic receptor inhibits insulin-stimulated leptin secretion from isolated rat adipocytes. Endocrinology 137: 4054-4057.
-
(1996)
Endocrinology
, vol.137
, pp. 4054-4057
-
-
Gettys, T.W.1
Harkness, P.J.2
Watson, P.M.3
-
43
-
-
0026343747
-
An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and downregulation in obesity
-
Muzzin P, Revelli JP, Kuhne F, Gocayne JD, McCombie WR, et al. (1991) An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and downregulation in obesity. J Biol Chem 266: 24053-24058.
-
(1991)
J Biol Chem
, vol.266
, pp. 24053-24058
-
-
Muzzin, P.1
Revelli, J.P.2
Kuhne, F.3
Gocayne, J.D.4
McCombie, W.R.5
-
44
-
-
0024470363
-
Molecular characterization of the human beta 3-adrenergic receptor
-
Emorine LJ, Marullo S, Briend-Sutren MM, Patey G, Tate K, et al. (1989) Molecular characterization of the human beta 3-adrenergic receptor. Science 245: 1118-1121.
-
(1989)
Science
, vol.245
, pp. 1118-1121
-
-
Emorine, L.J.1
Marullo, S.2
Briend-Sutren, M.M.3
Patey, G.4
Tate, K.5
-
45
-
-
0025940707
-
Molecular characterization of the mouse beta 3-adrenergic receptor: Relationship with the atypical receptor of adipocytes
-
Nahmias C, Blin N, Elalouf JM, Mattei MG, Strosberg AD, et al. (1991) Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes. EMBO J 10: 3721-3727.
-
(1991)
EMBO J
, vol.10
, pp. 3721-3727
-
-
Nahmias, C.1
Blin, N.2
Elalouf, J.M.3
Mattei, M.G.4
Strosberg, A.D.5
-
46
-
-
0026325126
-
Molecular cloning and expression of the rat beta 3-adrenergic receptor
-
Granneman JG, Lahners KN, Chaudhry A (1991) Molecular cloning and expression of the rat beta 3-adrenergic receptor. Mol Pharmacol 40: 895-899.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 895-899
-
-
Granneman, J.G.1
Lahners, K.N.2
Chaudhry, A.3
-
47
-
-
0027304781
-
Characterization of the human beta 3-adrenergic receptor gene
-
Granneman JG, Lahners KN, Chaudhry A (1993) Characterization of the human beta 3-adrenergic receptor gene. Mol Pharmacol 44: 264-270.
-
(1993)
Mol Pharmacol
, vol.44
, pp. 264-270
-
-
Granneman, J.G.1
Lahners, K.N.2
Chaudhry, A.3
-
48
-
-
0031721271
-
Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene
-
Nonogaki K, Strack AM, Dallman MF, Tecott LH (1998) Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene. Nat Med 4: 1152-1156.
-
(1998)
Nat Med
, vol.4
, pp. 1152-1156
-
-
Nonogaki, K.1
Strack, A.M.2
Dallman, M.F.3
Tecott, L.H.4
-
49
-
-
0028838836
-
Targeted disruption of the beta 3-adrenergic receptor gene
-
Susulic VS, Frederich RC, Lawitts J, Tozzo E, Kahn BB, et al. (1995) Targeted disruption of the beta 3-adrenergic receptor gene. J Biol Chem 270: 29483-29492.
-
(1995)
J Biol Chem
, vol.270
, pp. 29483-29492
-
-
Susulic, V.S.1
Frederich, R.C.2
Lawitts, J.3
Tozzo, E.4
Kahn, B.B.5
-
50
-
-
0037008157
-
betaAR signaling required for diet-induced thermogenesis and obesity resistance
-
Bachman ES, Dhillon H, Zhang CY, Cinti S, Bianco AC, et al. (2002) betaAR signaling required for diet-induced thermogenesis and obesity resistance. Science 297: 843-845.
-
(2002)
Science
, vol.297
, pp. 843-845
-
-
Bachman, E.S.1
Dhillon, H.2
Zhang, C.Y.3
Cinti, S.4
Bianco, A.C.5
-
51
-
-
77953481125
-
Adipose tissue activity in relation to overweight or obesity
-
Gnacinska M, Malgorzewicz S, Guzek M, Lysiak-Szydlowska W, Sworczak K (2010) Adipose tissue activity in relation to overweight or obesity. Endokrynol Pol 61: 160-168.
-
(2010)
Endokrynol Pol
, vol.61
, pp. 160-168
-
-
Gnacinska, M.1
Malgorzewicz, S.2
Guzek, M.3
Lysiak-Szydlowska, W.4
Sworczak, K.5
-
52
-
-
33947387967
-
Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue
-
Voss-Andreae A, Murphy JG, Ellacott KL, Stuart RC, Nillni EA, et al. (2007) Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology 148: 1550-1560.
-
(2007)
Endocrinology
, vol.148
, pp. 1550-1560
-
-
Voss-Andreae, A.1
Murphy, J.G.2
Ellacott, K.L.3
Stuart, R.C.4
Nillni, E.A.5
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