Cannabinoids increase conditioned ultrasonic vocalisations and cat odour avoidance in rats: Strain differences in drug-induced anxiety

Life Sciences

Volumn 87, Issue 17-18, 2010, Pages 572-578

  Arnold, Jonathon C ^a   Dielenberg, Robert A ^a   McGregor, Iain S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Anxiety; Cannabinoid; Cat odour; Conditioned ultrasonic vocalization; Rat; Strain difference

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 3-(2-HYDROXY-4-(1,1-DIMETHYLHEPTYL)PHENYL)-4-(3-HYDROXYPROPYL)CYCLOHEXANOL; CANNABINOID; CYCLOHEXANOL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN REGION; CAT; CONTROLLED STUDY; FOOTSHOCK; LEWIS RAT; MALE; NONHUMAN; ODOR; RAT; STRAIN DIFFERENCE; ULTRASOUND; VOCALIZATION; WISTAR RAT; ANIMAL; CHEMICALLY INDUCED; COMPARATIVE STUDY; CONDITIONING; DRUG EFFECTS; GENETICS; PHYSIOLOGY; PSYCHOLOGY; SPECIES DIFFERENCE; TOXICITY;

ANIMALS; ANXIETY; AVOIDANCE LEARNING; CANNABINOIDS; CATS; CONDITIONING (PSYCHOLOGY); CYCLOHEXANOLS; MALE; ODORS; RATS; RATS, INBRED LEW; RATS, WISTAR; SPECIES SPECIFICITY; ULTRASONICS; VOCALIZATION, ANIMAL;

ANIMALIA; CANNABIS; RATTUS; RATTUS NORVEGICUS;

EID: 77957857884     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.09.018     Document Type: Article

References (44)

1. Arnold J.C. The behavioural and neural effects of cannabinoids: studies using Lewis and Wistar strain rats 2000, School of Psychology, Sydney: University of Sydney.
2. Arnold J.C., Topple A.N., Hunt G.E., McGregor I.S. Effects of pre-exposure and co-administration of the cannabinoid receptor agonist CP 55, 940 on behavioral sensitization to cocaine. Eur J Pharmacol 1998, 354(1):9-16.
3. Arnold J.C., Hunt G.E., McGregor I.S. Effects of the cannabinoid receptor agonist CP 55, 940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats. Life Sci 2001, 70(1):97-108.
4. Arnold J.C., Topple A.N., Mallet P.E., Hunt G.E., McGregor I.S. The distribution of cannabinoid-induced Fos expression in rat brain: differences between the Lewis and Wistar strain. Brain Res 2001, 921(1-2):240-255.
5. Assie MB, Bardin L, Auclair AL, Carilla-Durand E, Depoortere R, Koek W, et al. F15599, a highly selective post-synaptic 5-HT1A receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity. Int J Neuropsychopharmacol 2010;13(10):1285-98.
6. Blanchard R.J., Blanchard D.C., Agullana R., Weiss S.M. Twenty-two kHz alarm cries to presentation of a predator, by laboratory rats living in visible burrow systems. Physiol Behav 1991, 50(5):967-972.
7. Bortolato M., Campolongo P., Mangieri R.A., Scattoni M.L., Frau R., Trezza V., et al. Anxiolytic-like properties of the anandamide transport inhibitor AM404. Neuropsychopharmacology 2006, 31(12):2652-2659.
8. Boucher A.A., Arnold J.C., Duffy L., Schofield P.R., Micheau J., Karl T. Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol. Psychopharmacology (Berl) 2007, 192(3):325-336.
9. Boucher A.A., Hunt G.E., Karl T., Micheau J., McGregor I.S., Arnold J.C. Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression. Neuroscience 2007, 149(4):861-870.
10. Boucher AA, Hunt GE, Micheau J, Huang XF, McGregor IS, Karl T, et al. The schizophrenia susceptibility gene neuregulin 1 modulates tolerance to the effects of cannabinoids. Int J Neuropsychopharmacol 2010;12:1-13.
11. Caspi A., Moffitt T.E., Cannon M., McClay J., Murray R., Harrington H., et al. Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry 2005, 57(10):1117-1127.
12. Chen J.P., Paredes W., Lowinson J.H., Gardner E.L. Strain-specific facilitation of dopamine efflux by delta 9-tetrahydrocannabinol in the nucleus accumbens of rat: an in vivo microdialysis study. Neurosci Lett 1991, 129(1):136-180.
13. Cullen W.K., Rowan M.J. Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat. Pharmacol Biochem Behav 1994, 48(1):301-306.
14. De Vry J., Benz U., Schreiber R., Traber J. Shock-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs. Eur J Pharmacol 1993, 249(3):331-339.
15. Dielenberg R.A., McGregor I.S. Habituation of the hiding response to cat odor in rats (Rattus norvegicus). J Comp Psychol 1999, 113(4):376-387.
16. Dielenberg R.A., McGregor I.S. Defensive behavior in rats towards predatory odors: a review. Neurosci Biobehav Rev 2001, 25(7-8):597-609.
17. Dielenberg R.A., Arnold J.C., McGregor I.S. Low-dose midazolam attenuates predatory odor avoidance in rats. Pharmacol Biochem Behav 1999, 62(2):197-201.
18. Gardner E.L., Vorel S.R. Cannabinoid transmission and reward-related events. Neurobiol Dis 1998, 5(6 Pt B):502-533.
19. Genn R.F., Tucci S., Marco E., Viveros M.P., File S.E. Anxiolytic and anxiogenic effects of the cannabinoid agonist CP 55, 940 in animal tests of anxiety. J Psychopharmacol 2003, 17(3). A27-A27.
20. Gold L.H., Balster R.L., Barrett R.L., Britt D.T., Martin B.R. A comparison of the discriminative stimulus properties of delta 9-tetrahydrocannabinol and CP 55, 940 in rats and rhesus monkeys. J Pharmacol Exp Ther 1992, 262(2):479-486.
21. Howell D.C. Statistical Methods for Psychology 1987, PWS-KENT, Boston.
22. Hunt G.E., Van Nieuwenhuijzen P.S., Chan-Ling T., McGregor I.S. 'When an old rat smells a cat': a decline in defense-related, but not accessory olfactory, Fos expression in aged rats. Neurobiol Aging 2009, [Electronic publication ahead of time].
23. Kathuria S., Gaetani S., Fegley D., Valino F., Duranti A., Tontini A., et al. Modulation of anxiety through blockade of anandamide hydrolysis. Nat Med 2003, 9(1):76-81.
24. Lepore M., Liu X., Savage V., Matalon D., Gardner E.L. Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. Life Sci 1996, 58(25):PL365-PL372.
25. Lichtman A.H., Martin B.R. Spinal and supraspinal components of cannabinoid-induced antinociception. J Pharmacol Exp Ther 1991, 258:517-523.
26. Lyons M.J., Toomey R., Meyer J.M., Green A.I., Eisen S.A., Goldberg J., et al. How do genes influence marijuana use? The role of subjective effects. Addiction 1997, 92(4):409-417.
27. Marco E.M., Perez-Alvarez L., Borcel E., Rubio M., Guaza C., Ambrosio E., et al. Involvement of 5-HT1A receptors in behavioural effects of the cannabinoid receptor agonist CP 55, 940 in male rats. Behav Pharmacol 2004, 15(1):21-27.
28. McGregor I.S., Dielenberg R.A. Differential anxiolytic efficacy of a benzodiazepine on first versus second exposure to a predatory odor in rats. Psychopharmacology (Berl) 1999, 147(2):174-181.
29. McGregor I.S., Dastur F.N., McLellan R.A., Brown R.E. Cannabinoid modulation of rat pup ultrasonic vocalizations. Eur J Pharmacol 1996, 313(1-2):43-49.
30. McGregor I.S., Issakidis C.N., Prior G. Aversive effects of the synthetic cannabinoid CP 55, 940 in rats. Pharmacol Biochem Behav 1996, 53(3):657-664.
31. McGregor I.S., Hargreaves G.A., Apfelbach R., Hunt G.E. Neural correlates of cat odor-induced anxiety in rats: region-specific effects of the benzodiazepine midazolam. J Neurosci 2004, 24(17):4134-4144.
32. Miczek K.A., Weerts E.M., Vivian J.A., Barros H.M. Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics. Psychopharmacology (Berl) 1995, 121(1):38-56.
33. Molewijk H.E., van der Poel A.M., Mos J., van der Heyden J.A., Olivier B. Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugs. Psychopharmacology 1995, 117(1):32-40.
34. Onaivi E.S., Chakrabarti A., Gwebu E.T., Chaudhuri G. Neurobehavioral effects of delta(9)-THC and cannabinoid (CB1) receptor gene expression in mice. Behav Brain Res 1995, 72(1-2):115-125.
35. Rex A., Sondern U., Voigt J.P., Franck S., Fink H. Strain differences in fear-motivated behavior of rats. Pharmacol Biochem Behav 1996, 54(1):107-111.
36. Rodgers R.J. Animal models of 'anxiety': where next?. Behav Pharmacol 1997, 8(6-7):477-496. discussion 497-504.
37. Rodriguez de Fonseca F., Rubio P., Menzaghi F., Merlo-Pich E., Rivier J., Koob G.F., et al. Corticotropin-releasing factor (CRF) antagonist [D-Phe12,Nle21,38,C alpha MeLeu37]CRF attenuates the acute actions of the highly potent cannabinoid receptor agonist HU-210 on defensive-withdrawal behavior in rats. J Pharmacol Exp Ther 1996, 276(1):56-64.
38. Rowan M.J., Cullen W.K., Moulton B. Buspirone impairment of performance of passive avoidance and spatial learning tasks in the rat. Psychopharmacology (Berl) 1990, 100(3):393-398.
39. Sutt S., Raud S., Areda T., Reimets A., Koks S., Vasar E. Cat odour-induced anxiety-a study of the involvement of the endocannabinoid system. Psychopharmacology (Berl) 2008, 198(4):509-520.
40. Valjent E., Mitchell J.M., Besson M.J., Caboche J., Maldonado R. Behavioural and biochemical evidence for interactions between Delta 9-tetrahydrocannabinol and nicotine. Br J Pharmacol 2002, 135(2):564-578.
41. van der Poel A.M., Noach E.J., Miczek K.A. Temporal patterning of ultrasonic distress calls in the adult rat: effects of morphine and benzodiazepines. Psychopharmacology (Berl) 1989, 97(2):147-148.
42. Vendruscolo L.F., Terenina-Rigaldie E., Raba F., Ramos A., Takahashi R.N., Mormede P. Evidence for a female-specific effect of a chromosome 4 locus on anxiety-related behaviors and ethanol drinking in rats. Genes Brain Behav 2006, 5(6):441-450.
43. Viveros M.P., Marco E.M., File S.E. Endocannabinoid system and stress and anxiety responses. Pharmacol Biochem Behav 2005, 81(2):331-342.
44. Welch S.P. Interaction of the cannabinoid and opioid systems in the modulation of nociception. Int Rev Psychiatry 2009, 21(2):143-151.