Design, synthesis and anticholinesterase activity of some new α-aminobisphosphonates

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 6, 2010, Pages 827-835

  Gholivand, Khodayar ^a   Ghaziani, Fatemeh ^a   Yaghoubi, Rouhollah ^a   Hosseini, Zahra ^a   Shariatinia, Zahra ^b  

^a TARBIAT MODARES UNIVERSITY   (Iran)

^b AMIRKABIR UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

Bisphosphonate; Ellman's method; Human erythrocyte acetylcholinesterase; IC50; Log P

Indexed keywords

ACETYLCHOLINESTERASE; ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CHOLINESTERASE INHIBITOR; HOMOPIPERAZINE 1,4 BIS(METHYLENEPHOSPHONIC ACID); N 2 ETHYL HEXYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N 2 PHENYL ETHYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N BENZYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N CYCLOHEXYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N CYCLOPENTYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N ETHYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N ISOPROPYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N METHYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N PENTYLIMINOBIS(METHYLENEPHOSPHONIC ACID); N PROPYLIMINOBIS(METHYLENEPHOSPHONIC ACID); UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; PRIORITY JOURNAL; SPECTROSCOPY;

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; DIPHOSPHONATES; DRUG DESIGN; ERYTHROCYTES; GPI-LINKED PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; ISOMERISM; KINETICS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77957856405     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756361003691860     Document Type: Article

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