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Volumn 460, Issue 4, 2010, Pages 743-753

The importance of serine 161 in the sodium channel β3 subunit for modulation of NaV1.2 gating

Author keywords

Auxiliary subunits; Electrophysiology; Immunohistochemistry; Site directed mutagenesis; Sodium channels

Indexed keywords

SERINE; SERINE 161; SODIUM CHANNEL; SODIUM CHANNEL BETA3; SODIUM CHANNEL NAV1.2; UNCLASSIFIED DRUG;

EID: 77957856183     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-009-0739-y     Document Type: Article
Times cited : (12)

References (42)
  • 1
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall WA (2000) From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron 26:13-25
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 3
    • 34548494836 scopus 로고    scopus 로고
    • Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: Implications for the evolution of electrical signaling in vertebrates
    • Chopra SS, Watanabe H, Zhong TP, Roden DM (2007) Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: implications for the evolution of electrical signaling in vertebrates. BMC Evol Biol 7:113
    • (2007) BMC Evol Biol , vol.7 , pp. 113
    • Chopra, S.S.1    Watanabe, H.2    Zhong, T.P.3    Roden, D.M.4
  • 4
    • 0018110116 scopus 로고
    • Prediction of the secondary structure of proteins from their amino acid sequence
    • Chou PY, Fasman GD (1978) Prediction of the secondary structure of proteins from their amino acid sequence. Adv Enzymol Relat Areas Mol Biol 47:45-148
    • (1978) Adv Enzymol Relat Areas Mol Biol , vol.47 , pp. 45-148
    • Chou, P.Y.1    Fasman, G.D.2
  • 5
    • 37249050304 scopus 로고    scopus 로고
    • Trafficking and cellular distribution of voltage-gated sodium channels
    • Cusdin FS, Clare JJ, Jackson AP (2008) Trafficking and cellular distribution of voltage-gated sodium channels. Traffic 9:17-26
    • (2008) Traffic , vol.9 , pp. 17-26
    • Cusdin, F.S.1    Clare, J.J.2    Jackson, A.P.3
  • 6
    • 0001040367 scopus 로고
    • An algorithm for protein secondary structure prediction based on class prediction
    • Deleage G, Roux B (1987) An algorithm for protein secondary structure prediction based on class prediction. Protein Eng 1:289-294
    • (1987) Protein Eng , vol.1 , pp. 289-294
    • Deleage, G.1    Roux, B.2
  • 7
    • 0017873321 scopus 로고
    • Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
    • Garnier J, Osguthorpe DJ, Robson B (1978) Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J Mol Biol 120:97-120
    • (1978) J Mol Biol , vol.120 , pp. 97-120
    • Garnier, J.1    Osguthorpe, D.J.2    Robson, B.3
  • 8
    • 0038721687 scopus 로고    scopus 로고
    • Mechanisms of sodium channel inactivation
    • Goldin AL (2003) Mechanisms of sodium channel inactivation. Curr Opin Neurobiol 13:284-290
    • (2003) Curr Opin Neurobiol , vol.13 , pp. 284-290
    • Goldin, A.L.1
  • 9
    • 12344303542 scopus 로고    scopus 로고
    • Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current
    • Grieco TM, Malhotra JD, Chen C, Isom LL, Raman IM (2005) Open-channel block by the cytoplasmic tail of sodium channel beta4 as a mechanism for resurgent sodium current. Neuron 45:233-244
    • (2005) Neuron , vol.45 , pp. 233-244
    • Grieco, T.M.1    Malhotra, J.D.2    Chen, C.3    Isom, L.L.4    Raman, I.M.5
  • 10
    • 0035139342 scopus 로고    scopus 로고
    • Sodium channel beta subunits: Anything but auxiliary
    • Isom LL (2001) Sodium channel beta subunits: anything but auxiliary. Neuroscientist 7:42-54
    • (2001) Neuroscientist , vol.7 , pp. 42-54
    • Isom, L.L.1
  • 11
    • 0026551357 scopus 로고
    • Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel
    • Isom LL, De Jongh KS, Patton DE et al (1992) Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel. Science 256:839-842
    • (1992) Science , vol.256 , pp. 839-842
    • Isom, L.L.1    De Jongh, K.S.2    Patton, D.E.3
  • 12
    • 0028972374 scopus 로고
    • Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
    • Isom LL, Ragsdale DS, De Jongh KS et al (1995) Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif. Cell 83:433-442
    • (1995) Cell , vol.83 , pp. 433-442
    • Isom, L.L.1    Ragsdale, D.S.2    De Jongh, K.S.3
  • 13
    • 0028980448 scopus 로고
    • Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line
    • Isom LL, Scheuer T, Brownstein AB, Ragsdale DS, Murphy BJ, Catterall WA (1995) Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell line. J Biol Chem 270:3306-3312
    • (1995) J Biol Chem , vol.270 , pp. 3306-3312
    • Isom, L.L.1    Scheuer, T.2    Brownstein, A.B.3    Ragsdale, D.S.4    Murphy, B.J.5    Catterall, W.A.6
  • 14
    • 33748741303 scopus 로고    scopus 로고
    • Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating
    • Johnson D, Bennett ES (2006) Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating. J Biol Chem 281:25875-25881
    • (2006) J Biol Chem , vol.281 , pp. 25875-25881
    • Johnson, D.1    Bennett, E.S.2
  • 15
    • 15044340142 scopus 로고    scopus 로고
    • Modulation of Na(v)1.5bybeta1- and beta3-subunit co- expression in mammalian cells
    • Ko SH, Lenkowski PW, Lee HC, Mounsey JP, Patel MK (2005) ModulationofNa(v)1.5bybeta1- and beta3-subunit co- expression in mammalian cells. Pflugers Arch 449:403-412
    • (2005) Pflugers Arch , vol.449 , pp. 403-412
    • Ko, S.H.1    Lenkowski, P.W.2    Lee, H.C.3    Mounsey, J.P.4    Patel, M.K.5
  • 16
    • 0025882870 scopus 로고
    • Systematic analysis of stop-transfer sequence for microsomal membrane
    • Kuroiwa T, Sakaguchi M, Mihara K, Omura T (1991) Systematic analysis of stop-transfer sequence for microsomal membrane. J Biol Chem 266:9251-9255
    • (1991) J Biol Chem , vol.266 , pp. 9251-9255
    • Kuroiwa, T.1    Sakaguchi, M.2    Mihara, K.3    Omura, T.4
  • 17
    • 0018093765 scopus 로고
    • Conformational preferences of amino acids in globular proteins
    • Levitt M (1978) Conformational preferences of amino acids in globular proteins. Biochemistry 17:4277-4285
    • (1978) Biochemistry , vol.17 , pp. 4277-4285
    • Levitt, M.1
  • 18
    • 0034602841 scopus 로고    scopus 로고
    • Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)- subunit
    • Makita N, Shirai N, Wang DW et al (2000) Cardiac Na(+) channel dysfunction in Brugada syndrome is aggravated by beta(1)- subunit. Circulation 101:54-60
    • (2000) Circulation , vol.101 , pp. 54-60
    • Makita, N.1    Shirai, N.2    Wang, D.W.3
  • 20
    • 0032512652 scopus 로고    scopus 로고
    • Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit
    • McCormick KA, Isom LL, Ragsdale D, Smith D, Scheuer T, Catterall WA (1998) Molecular determinants of Na+ channel function in the extracellular domain of the beta1 subunit. J Biol Chem 273:3954-3962
    • (1998) J Biol Chem , vol.273 , pp. 3954-3962
    • McCormick, K.A.1    Isom, L.L.2    Ragsdale, D.3    Smith, D.4    Scheuer, T.5    Catterall, W.A.6
  • 21
    • 1942501741 scopus 로고    scopus 로고
    • Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin
    • McEwen DP, Meadows LS, Chen C, Thyagarajan V, Isom LL (2004) Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin. J Biol Chem 279:16044-16049
    • (2004) J Biol Chem , vol.279 , pp. 16044-16049
    • McEwen, D.P.1    Meadows, L.S.2    Chen, C.3    Thyagarajan, V.4    Isom, L.L.5
  • 22
    • 0035107612 scopus 로고    scopus 로고
    • The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit
    • Meadows L, Malhotra JD, Stetzer A, Isom LL, Ragsdale DS (2001) The intracellular segment of the sodium channel beta 1 subunit is required for its efficient association with the channel alpha subunit. J Neurochem 76:1871-1878
    • (2001) J Neurochem , vol.76 , pp. 1871-1878
    • Meadows, L.1    Malhotra, J.D.2    Stetzer, A.3    Isom, L.L.4    Ragsdale, D.S.5
  • 23
    • 0037115031 scopus 로고    scopus 로고
    • Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1
    • Meadows LS, Malhotra J, Loukas A et al (2002) Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1. J Neurosci 22:10699-10709
    • (2002) J Neurosci , vol.22 , pp. 10699-10709
    • Meadows, L.S.1    Malhotra, J.2    Loukas, A.3
  • 24
    • 34447307435 scopus 로고    scopus 로고
    • SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome
    • Medeiros-Domingo A, Kaku T, Tester DJ et al (2007) SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome. Circulation 116:134-142
    • (2007) Circulation , vol.116 , pp. 134-142
    • Medeiros-Domingo, A.1    Kaku, T.2    Tester, D.J.3
  • 25
    • 12944260700 scopus 로고    scopus 로고
    • Beta 3: An additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics
    • Morgan K, Stevens EB, Shah B et al (2004) beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. Proc Natl Acad Sci USA 97:2308-2313
    • (2004) Proc Natl Acad Sci USA , vol.97 , pp. 2308-2313
    • Morgan, K.1    Stevens, E.B.2    Shah, B.3
  • 26
    • 0842326191 scopus 로고    scopus 로고
    • The Na+ channel inactivation gate is a molecular complex: A novel role of the COOH-terminal domain
    • Motoike HK, Liu H, Glaaser IW, Yang AS, Tateyama M, Kass RS (2004) The Na+ channel inactivation gate is a molecular complex: A novel role of the COOH-terminal domain. J Gen Physiol 123:155-165
    • (2004) J Gen Physiol , vol.123 , pp. 155-165
    • Motoike, H.K.1    Liu, H.2    Glaaser, I.W.3    Yang, A.S.4    Tateyama, M.5    Kass, R.S.6
  • 27
    • 0029417096 scopus 로고
    • Functional association of the beta 1 subunit with human cardiac (hH1) and rat skeletal muscle (mu 1) sodium channel alpha subunits expressed in Xenopus oocytes
    • Nuss HB, Chiamvimonvat N, Perez-Garcia MT, Tomaselli GF, Marban E (1995) Functional association of the beta 1 subunit with human cardiac (hH1) and rat skeletal muscle (mu 1) sodium channel alpha subunits expressed in Xenopus oocytes. J Gen Physiol 106:1171-1191
    • (1995) J Gen Physiol , vol.106 , pp. 1171-1191
    • Nuss, H.B.1    Chiamvimonvat, N.2    Perez-Garcia, M.T.3    Tomaselli, G.F.4    Marban, E.5
  • 28
    • 0032725558 scopus 로고    scopus 로고
    • Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits
    • Qu Y, Rogers JC, Chen SF, McCormick KA, Scheuer T, Catterall WA (1999) Functional roles of the extracellular segments of the sodium channel alpha subunit in voltage-dependent gating and modulation by beta1 subunits. J Biol Chem 274:32647-32654
    • (1999) J Biol Chem , vol.274 , pp. 32647-32654
    • Qu, Y.1    Rogers, J.C.2    Chen, S.F.3    McCormick, K.A.4    Scheuer, T.5    Catterall, W.A.6
  • 29
    • 0024365824 scopus 로고
    • Phosphorylation of the alpha subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687
    • Rossie S, Catterall WA (1989) Phosphorylation of the alpha subunit of rat brain sodium channels by cAMP-dependent protein kinase at a new site containing Ser686 and Ser687. J Biol Chem 264:14220-14224
    • (1989) J Biol Chem , vol.264 , pp. 14220-14224
    • Rossie, S.1    Catterall, W.A.2
  • 30
    • 35348866221 scopus 로고    scopus 로고
    • Modulatory proteins can rescue a trafficking defective epileptogenic Nav1.1 Na+ channel mutant
    • Rusconi R, Scalmani P, Cassulini RR et al (2007) Modulatory proteins can rescue a trafficking defective epileptogenic Nav1.1 Na+ channel mutant. J Neurosci 27:11037-11046
    • (2007) J Neurosci , vol.27 , pp. 11037-11046
    • Rusconi, R.1    Scalmani, P.2    Cassulini, R.R.3
  • 31
    • 20844446135 scopus 로고    scopus 로고
    • A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction
    • Spampanato J, Kearney JA, de Haan G et al (2004) A novel epilepsy mutation in the sodium channel SCN1A identifies a cytoplasmic domain for beta subunit interaction. J Neurosci 24:10022-10034
    • (2004) J Neurosci , vol.24 , pp. 10022-10034
    • Spampanato, J.1    Kearney, J.A.2    De Haan, G.3
  • 32
    • 25444498065 scopus 로고    scopus 로고
    • Sodium channel inactivation: molecular determinants and modulation
    • Ulbricht W (2005) Sodium channel inactivation: molecular determinants and modulation. Physiol Rev 85:1271-1301
    • (2005) Physiol Rev , vol.85 , pp. 1271-1301
    • Ulbricht, W.1
  • 33
    • 77957849270 scopus 로고    scopus 로고
    • Identification and Characterization of a Novel Susceptibility Gene, SCN3B, for Idiopathic Venricular Fibrillation
    • Valdivia C, Mereudos-Domingo A, Algiers TJ, Ackerman MJ, Makielski JC (2008) Identification and Characterization of a Novel Susceptibility Gene, SCN3B, for Idiopathic Venricular Fibrillation. Circulation 118:S526
    • (2008) Circulation , vol.118
    • Valdivia, C.1    Mereudos-Domingo, A.2    Algiers, T.J.3    Ackerman, M.J.4    Makielski, J.C.5
  • 34
    • 4344662040 scopus 로고    scopus 로고
    • PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
    • Viard P, Butcher AJ, Halet G et al (2004) PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane. Nat Neurosci 7:939-946
    • (2004) Nat Neurosci , vol.7 , pp. 939-946
    • Viard, P.1    Butcher, A.J.2    Halet, G.3
  • 35
    • 0033104768 scopus 로고    scopus 로고
    • Hydrogen bonds between short polar side chains and peptide backbone: Prevalence in proteins and effects on helix-forming propensities
    • Vijayakumar M, Qian H, Zhou HX (1999) Hydrogen bonds between short polar side chains and peptide backbone: prevalence in proteins and effects on helix-forming propensities. Proteins 34:497-507
    • (1999) Proteins , vol.34 , pp. 497-507
    • Vijayakumar, M.1    Qian, H.2    Zhou, H.X.3
  • 36
    • 17344367657 scopus 로고    scopus 로고
    • Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B
    • Wallace RH, Wang DW, Singh R et al (1998) Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B. Nat Genet 19:366-370
    • (1998) Nat Genet , vol.19 , pp. 366-370
    • Wallace, R.H.1    Wang, D.W.2    Singh, R.3
  • 37
    • 34547670914 scopus 로고    scopus 로고
    • Generalized epilepsy with febrile seizures plus-associated sodium channel beta1 subunit mutations severely reduce beta subunit-mediated modulation of sodium channel function
    • Xu R, Thomas EA, Gazina EV et al (2007) Generalized epilepsy with febrile seizures plus-associated sodium channel beta1 subunit mutations severely reduce beta subunit-mediated modulation of sodium channel function. Neuroscience 148:164-174
    • (2007) Neuroscience , vol.148 , pp. 164-174
    • Xu, R.1    Thomas, E.A.2    Gazina, E.V.3
  • 38
    • 29644441868 scopus 로고    scopus 로고
    • Distinct domains of the sodium channel beta3-subunit modulate channel-gating kinetics and subcellular location
    • Yu EJ, Ko SH, Lenkowski PW, Pance A, Patel MK, Jackson AP (2005) Distinct domains of the sodium channel beta3-subunit modulate channel-gating kinetics and subcellular location. Biochem J 392:519-526
    • (2005) Biochem J , vol.392 , pp. 519-526
    • Yu, E.J.1    Ko, S.H.2    Lenkowski, P.W.3    Pance, A.4    Patel, M.K.5    Jackson, A.P.6
  • 39
    • 0037264170 scopus 로고    scopus 로고
    • Overview of the voltage-gated sodium channel family
    • Yu FH, Catterall WA (2007) Overview of the voltage-gated sodium channel family. Genome Biol 4:207
    • (2007) Genome Biol , vol.4 , pp. 207
    • Yu, F.H.1    Catterall, W.A.2
  • 40
    • 0041419702 scopus 로고    scopus 로고
    • Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2
    • Yu FH, Westenbroek RE, Silos-Santiago I et al (2003) Sodium channel beta4, a new disulfide-linked auxiliary subunit with similarity to beta2. J Neurosci 23:7577-7585
    • (2003) J Neurosci , vol.23 , pp. 7577-7585
    • Yu, F.H.1    Westenbroek, R.E.2    Silos-Santiago, I.3
  • 41
    • 55449094135 scopus 로고    scopus 로고
    • The voltage-gated Na+ channel Nav1.8 contains an ER-retention/ retrieval signal antagonized by the beta3 subunit
    • Zhang ZN, Li Q, Liu C, Wang HB, Wang Q, Bao L (2008) The voltage-gated Na+ channel Nav1.8 contains an ER-retention/ retrieval signal antagonized by the beta3 subunit. J Cell Sci 121:3243-3252
    • (2008) J Cell Sci , vol.121 , pp. 3243-3252
    • Zhang, Z.N.1    Li, Q.2    Liu, C.3    Wang, H.B.4    Wang, Q.5    Bao, L.6
  • 42
    • 0036489217 scopus 로고    scopus 로고
    • The beta1 subunit but not the beta2 subunit colocalizes with the human heart Na+ channel (hH1) already within the endoplasmic reticulum
    • Zimmer T, Biskup C, Bollensdorff C, Benndorf K (2002) The beta1 subunit but not the beta2 subunit colocalizes with the human heart Na+ channel (hH1) already within the endoplasmic reticulum. J Membr Biol 186:13-21
    • (2002) J Membr Biol , vol.186 , pp. 13-21
    • Zimmer, T.1    Biskup, C.2    Bollensdorff, C.3    Benndorf, K.4


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