Cholinergic enhancement augments magnitude and specificity of visual perceptual learning in healthy humans

Current Biology

Volumn 20, Issue 19, 2010, Pages 1723-1728

  Rokem, Ariel ^a   Silver, Michael A ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE INHIBITOR; DONEPEZIL; INDAN DERIVATIVE; PIPERIDINE DERIVATIVE; PLACEBO;

ADOLESCENT; ADULT; ANIMAL; ARTICLE; DRUG EFFECT; FEMALE; HUMAN; LEARNING; METABOLISM; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; VISION;

ACETYLCHOLINE; ADOLESCENT; ADULT; ANIMALS; CHOLINESTERASE INHIBITORS; FEMALE; HUMANS; INDANS; LEARNING; NEUROPSYCHOLOGICAL TESTS; PIPERIDINES; PLACEBOS; VISUAL PERCEPTION; YOUNG ADULT;

EID: 77957843766     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.08.027     Document Type: Article

References (40)

1. M. Sarter, M.E. Hasselmo, J.P. Bruno, and B. Givens Unraveling the attentional functions of cortical cholinergic inputs: Interactions between signal-driven and cognitive modulation of signal detection Brain Res. Brain Res. Rev. 48 2005 98 111 (Pubitemid 40215784)
2. K. Ball, and R. Sekuler A specific and enduring improvement in visual motion discrimination Science 218 1982 697 698 (Pubitemid 12005451)
3. M.L. Furey, P. Pietrini, and J.V. Haxby Cholinergic enhancement and increased selectivity of perceptual processing during working memory Science 290 2000 2315 2319 (Pubitemid 32041576)
4. M.J. Roberts, W. Zinke, K. Guo, R. Robertson, J.S. McDonald, and A. Thiele Acetylcholine dynamically controls spatial integration in marmoset primary visual cortex J. Neurophysiol. 93 2005 2062 2072 (Pubitemid 40404406)
5. M.A. Silver, A. Shenhav, and M. D'Esposito Cholinergic enhancement reduces spatial spread of visual responses in human early visual cortex Neuron 60 2008 904 914
6. H.M. Arnold, J.A. Burk, E.M. Hodgson, M. Sarter, and J.P. Bruno Differential cortical acetylcholine release in rats performing a sustained attention task versus behavioral control tasks that do not explicitly tax attention Neuroscience 114 2002 451 460 (Pubitemid 35245424)
7. J.M. Greuel, H.J. Luhmann, and W. Singer Pharmacological induction of use-dependent receptive field modifications in the visual cortex Science 242 1988 74 77
8. M.P. Kilgard, and M.M. Merzenich Cortical map reorganization enabled by nucleus basalis activity Science 279 1998 1714 1718
9. C.M. Thiel, K.J. Friston, and R.J. Dolan Cholinergic modulation of experience-dependent plasticity in human auditory cortex Neuron 35 2002 567 574 (Pubitemid 34879954)
10. K.L. Davis, R.C. Mohs, J.R. Tinklenberg, A. Pfefferbaum, L.E. Hollister, and B.S. Kopell Physostigmine: Improvement of long-term memory processes in normal humans Science 201 1978 272 274
11. P. Bentley, M. Husain, and R.J. Dolan Effects of cholinergic enhancement on visual stimulation, spatial attention, and spatial working memory Neuron 41 2004 969 982 (Pubitemid 38429739)
12. M. Fahle, T. Poggio, Perceptual Learning 2002 MIT Press Cambridge, MA
13. C.S. Furmanski, D. Schluppeck, and S.A. Engel Learning strengthens the response of primary visual cortex to simple patterns Curr. Biol. 14 2004 573 578 (Pubitemid 38458946)
14. T. Yang, and J.H. Maunsell The effect of perceptual learning on neuronal responses in monkey visual area V4 J. Neurosci. 24 2004 1617 1626 (Pubitemid 38240957)
15. G.M. Ghose, T. Yang, and J.H. Maunsell Physiological correlates of perceptual learning in monkey V1 and V2 J. Neurophysiol. 87 2002 1867 1888 (Pubitemid 34670752)
16. A. Schoups, R. Vogels, N. Qian, and G. Orban Practising orientation identification improves orientation coding in V1 neurons Nature 412 2001 549 553 (Pubitemid 32743834)
17. A.B. Watson, and D.G. Pelli QUEST: A Bayesian adaptive psychometric method Percept. Psychophys. 33 1983 113 120
18. D.G. Pelli The VideoToolbox software for visual psychophysics: Transforming numbers into movies Spat. Vis. 10 1997 437 442
19. D.H. Brainard The Psychophysics Toolbox Spat. Vis. 10 1997 433 436
20. S.L. Rogers, N.M. Cooper, R. Sukovaty, J.E. Pederson, J.N. Lee, and L.T. Friedhoff Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses Br. J. Clin. Pharmacol. 46 Suppl 1 1998 7 12 (Pubitemid 29197008)
21. K. Ball, and R. Sekuler Direction-specific improvement in motion discrimination Vision Res. 27 1987 953 965 (Pubitemid 17104458)
22. A. Rokem, and M.A. Silver A model of encoding and decoding in V1 and MT accounts for motion perception anisotropies in the human visual system Brain Res. 1299 2009 3 16
23. P. Bentley, P. Vuilleumier, C.M. Thiel, J. Driver, and R.J. Dolan Cholinergic enhancement modulates neural correlates of selective attention and emotional processing Neuroimage 20 2003 58 70 (Pubitemid 37188499)
24. G. Grön, M. Kirstein, A. Thielscher, M.W. Riepe, and M. Spitzer Cholinergic enhancement of episodic memory in healthy young adults Psychopharmacology (Berl.) 182 2005 170 179 (Pubitemid 41400874)
25. P.J. Nathan, A. Baker, E. Carr, J. Earle, M. Jones, M. Nieciecki, C. Hutchison, and C. Stough Cholinergic modulation of cognitive function in healthy subjects: Acute effects of donepezil, a cholinesterase inhibitor Hum. Psychopharmacol. 16 2001 481 483 (Pubitemid 32895592)
26. L.M. Giocomo, and M.E. Hasselmo Neuromodulation by glutamate and acetylcholine can change circuit dynamics by regulating the relative influence of afferent input and excitatory feedback Mol. Neurobiol. 36 2007 184 200
27. F. Kimura, M. Fukuda, and T. Tsumoto Acetylcholine suppresses the spread of excitation in the visual cortex revealed by optical recording: Possible differential effect depending on the source of input Eur. J. Neurosci. 11 1999 3597 3609 (Pubitemid 29484256)
28. M. Goard, and Y. Dan Basal forebrain activation enhances cortical coding of natural scenes Nat. Neurosci. 12 2009 1444 1449
29. M. Sarter, J.P. Bruno, and B. Givens Attentional functions of cortical cholinergic inputs: What does it mean for learning and memory? Neurobiol. Learn. Mem. 80 2003 245 256 (Pubitemid 37159352)
30. M. Ahissar, and S. Hochstein Attentional control of early perceptual learning Proc. Natl. Acad. Sci. USA 90 1993 5718 5722 (Pubitemid 23176233)
31. A. Rokem, A.N. Landau, D. Garg, W. Prinzmetal, and M.A. Silver Cholinergic enhancement increases the effects of voluntary attention but does not affect involuntary attention Neuropsychopharmacology 2010 10.1038/npp.2010.118 Published online September 1, 2010
32. J.L. Herrero, M.J. Roberts, L.S. Delicato, M.A. Gieselmann, P. Dayan, and A. Thiele Acetylcholine contributes through muscarinic receptors to attentional modulation in V1 Nature 454 2008 1110 1114
33. T. Watanabe, J.E. Náñez, and Y. Sasaki Perceptual learning without perception Nature 413 2001 844 848 (Pubitemid 33026851)
34. A.R. Seitz, and T. Watanabe Psychophysics: Is subliminal learning really passive? Nature 422 2003 36
35. S. Nishina, A.R. Seitz, M. Kawato, and T. Watanabe Effect of spatial distance to the task stimulus on task-irrelevant perceptual learning of static Gabors J. Vis. 7 2007 1 10
36. V. Parikh, R. Kozak, V. Martinez, and M. Sarter Prefrontal acetylcholine release controls cue detection on multiple timescales Neuron 56 2007 141 154 (Pubitemid 47484179)
37. P.R. Roelfsema, A. van Ooyen, and T. Watanabe Perceptual learning rules based on reinforcers and attention Trends Cogn. Sci. 14 2010 64 71
38. T. Kosasa, Y. Kuriya, K. Matsui, and Y. Yamanishi Inhibitory effects of donepezil hydrochloride (E2020) on cholinesterase activity in brain and peripheral tissues of young and aged rats Eur. J. Pharmacol. 386 1999 7 13 (Pubitemid 30009617)
39. S.L. Rogers, Y. Yamanishi, and K. Yamatsu E2020: The pharmacology of a piperidine cholinesterase inhibitor R. Becker, E. Giacobini, Cholinergic Basis for Alzheimer Therapy 1991 Birkhäuser Boston, MA
40. S. Estermann, G.-C. Daepp, K. Cattapan-Ludewig, M. Berkhoff, B.E. Frueh, and D. Goldblum Effect of oral donepezil on intraocular pressure in normotensive Alzheimer patients J. Ocul. Pharmacol. Ther. 22 2006 62 67 (Pubitemid 43364082)