QSAR modeling, synthesis and bioassay of diverse leukemia RPMI-8226 cell line active agents

European Journal of Medicinal Chemistry

Volumn 45, Issue 11, 2010, Pages 5183-5199

  Katritzky, Alan R ^a   Girgis, Adel S ^a,b   Slavov, Svetoslav ^a   Tala, Srinivasa R ^a   Stoyanova Slavova, Iva ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Anti tumor agents; Bis(oxy)bis urea derivatives; Bis(sulfanediyl)bis urea derivatives; CODESSA PRO; Leukemia RPMI 8226 cell line; QSAR

Indexed keywords

1,1' [2,2' [BUTANE 1,4 DIYLBIS(SULFANEDIYL)]BIS(2,1 PHENYLENE)]BIS[3 (4 CHLOROPHENYL)UREA]; 1,1' [2,2' [BUTANE 1,4 DIYLBIS(SULFANEDIYL)]BIS(2,1 PHENYLENE)]BIS[3 (4 METHOXYPHENYL)UREA]; 1,1' [2,2' [PROPANE 1,3 DIYLBIS(OXY)]BIS(2,1 PHENYLENE)]BIS[3 (4 METHOXYPHENYL)UREA]; 1,1' [4,4' [PROPANE 1,3 DIYLBIS(OXY)]BIS(4,1 PHENYLENE)]BIS[3 (4 CHLOROPHENYL)UREA]; 1,1' [4,4' [PROPANE 1,3 DIYLBIS(OXY)]BIS(4,1 PHENYLENE)]BIS[3 (4 METHOXYPHENYL)UREA]; 2,2' [1,4 BUTANEDIYLBIS(THIO)]BISBENZENAMINE; 4,4' [PROPANE 1,3 DIYLBIS(OXY)]DIANILINE; ANTINEOPLASTIC AGENT; N,N' [2,2' [PROPANE 1,3 DIYL(OXY)]BIS(2,1 PHENYLENE)]DIACETAMIDE; N,N' [4,4' [PROPANE 1,3 DIYL(OXY)]BIS(4,1 PHENYLENE)]DIACETAMIDE; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; COLON CANCER; CONTROLLED STUDY; DRUG INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; KIDNEY CANCER; LEUKEMIA CELL; LUNG NON SMALL CELL CANCER; OVARY CANCER; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LEUKEMIA; MAGNETIC RESONANCE SPECTROSCOPY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STATIC ELECTRICITY;

EID: 77957824684     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.08.033     Document Type: Article

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