Association of circulating C-reactive protein and interleukin-6 with longevity into the 80s and 90s: The Rancho Bernardo Study

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 10, 2010, Pages 4748-4755

  Wassel, Christina L ^a   Barrett Connor, Elizabeth ^a   Laughlin, Gail A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6;

AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; ESTROGEN THERAPY; FEMALE; FOLLOW UP; GROUPS BY AGE; HUMAN; HUMAN EXPERIMENT; LIFESPAN; LONGEVITY; MALE; MORTALITY; POSTMENOPAUSE; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SURVIVAL TIME;

EID: 77957815648     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2010-0473     Document Type: Article

References (42)

1. Abeywardena MY, Leifert WR, Warnes KE, Varghese JN, Head RJ 2009 Cardiovascular biology of interleukin-6. Curr Pharm Des 15:1809-1821
2. Garg R, Tripathy D, Dandona P 2003 Insulin resistance as a proinflammatory state: mechanisms, mediators, and therapeutic interventions. Curr Drug Targets 4:487-492
3. Packard RR, Libby P 2008 Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem 54:24-38
4. Pasceri V, Willerson JT, Yeh ET 2000 Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 102:2165-2168
5. Schuett H, Luchtefeld M, Grothusen C, Grote K, Schieffer B 2009 How much is too much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost 102:215-222
6. Cesari M, Penninx BW, Newman AB, Kritchevsky SB, Nicklas BJ, Sutton-Tyrrell K, Rubin SM, Ding J, Simonsick EM, Harris TB, Pahor M 2003 Inflammatory markers and onset of cardiovascular events: results from the health ABC study. Circulation 108:2317-2322
7. Cushman M, Arnold AM, Psaty BM, Manolio TA, Kuller LH, Burke GL, Polak JF, Tracy RP 2005 C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the cardiovascular health study. Circulation 112:25-31
8. Folsom AR, Aleksic N, Catellier D, Juneja HS, Wu KK 2002 C-reactive protein and incident coronary heart disease in the atherosclerosis risk in communities (ARIC) study. Am Heart J 144:233-238 (Pubitemid 34879645)
9. Ridker PM, Buring JE, Shih J, Matias M, Hennekens CH 1998 Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 98:731-733
10. Harris TB, Ferrucci L, Tracy RP, Corti MC, Wacholder S, Ettinger Jr WH, Heimovitz H, Cohen HJ, Wallace R 1999 Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med 106:506-512
11. Strandberg TE, Tilvis RS 2000 C-reactive protein, cardiovascular risk factors, and mortality in a prospective study in the elderly. Arterioscler Thromb Vasc Biol 20:1057-1060
12. Tuomisto K, Jousilahti P, Sundvall J, Pajunen P, Salomaa V 2006 C-reactive protein, interleukin-6 and tumor necrosis factor α as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study. Thromb Haemost 95:511-518
13. Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, Ahmad S 2001 Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86:3257-3265
14. Barzilay JI, Abraham L, Heckbert SR, Cushman M, Kuller LH, Resnick HE, Tracy RP 2001 The relation of markers of inflammation to the development of glucose disorders in the elderly: the cardiovascular health study. Diabetes 50:2384-2389
15. Lacquemant C, Vasseur F, Lepretre F, Froguel P 2005 [Adipocytokins, obesity and development of type 2 diabetes]. Med Sci (Paris) 21 Spec No:10-18 (French)
16. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM 2001 C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286:327-334
17. Pradhan AD, Cook NR, Buring JE, Manson JE, Ridker PM 2003 C-reactive protein is independently associated with fasting insulin in nondiabetic women. Arterioscler Thromb Vasc Biol 23:650-655
18. Capri M, Salvioli S, Sevini F, Valensin S, Celani L, Monti D, Pawelec G, De Benedictis G, Gonos ES, Franceschi C 2006 The genetics of human longevity. Ann NY Acad Sci 1067:252-263
19. Herskind AM, McGue M, Holm NV, Sørensen TI, Harvald B, Vaupel JW 1996 The heritability of human longevity: A population-based study of 2872 danish twin pairs born 1870-1900. Hum Genet 97:319-323
20. McGue M, Vaupel JW, Holm N, Harvald B 1993 Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J Gerontol 48:B237-B244
21. Mitchell BD, Hsueh WC, King TM, Pollin TI, Sorkin J, Agarwala R, Schäffer AA, Shuldiner AR 2001 Heritability of life span in the Old Order Amish. Am J Med Genet 102:346-352
22. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D 1999 A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group. Ann Intern Med 130:461-470
23. Friedewald WT, Levy RI, Fredrickson DS 1972 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499-502
24. Cartier A, Côté M, Lemieux I, Pérusse L, Tremblay A, Bouchard C, Després JP 2009 Sex differences in inflammatory markers: what is the contribution of visceral adiposity? Am J Clin Nutr 89:1307-1314
25. Swindell WR 2009 Accelerated failure time models provide a useful statistical framework for aging research. Exp Gerontol 44:190-200
26. Criqui MH, Ho LA, Denenberg JO, Ridker PM, Wassel CL, McDermott MM 2010 Biomarkers in peripheral arterial disease patients and near and longer term mortality J Vasc Surg 52:85-90
27. Jenny NS, Yanez ND, Psaty BM, Kuller LH, Hirsch CH, Tracy RP 2007 Inflammation biomarkers and near-term death in older men. Am J Epidemiol 165:684-695
28. Vidula H, Tian L, Liu K, Criqui MH, Ferrucci L, Pearce WH, Greenland P, Green D, Tan J, Garside DB, Guralnik J, Ridker PM, Rifai N, McDermott MM 2008 Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study. Ann Intern Med 148:85-93
29. Arai Y, Takayama M, Gondo Y, Inagaki H, Yamamura K, Nakazawa S, Kojima T, Ebihara Y, Shimizu K, Masui Y, Kitagawa K, Takebayashi T, Hirose N 2008 Adipose endocrine function, insulin-like growth factor-1 axis, and exceptional survival beyond 100 years of age. J Gerontol A Biol Sci Med Sci 63:1209-1218
30. Jylhä M, Paavilainen P, Lehtimäki T, Goebeler S, Karhunen PJ, Hervonen A, Hurme M 2007 Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ study. J Gerontol A Biol Sci Med Sci 62:1016-1021
31. Kravitz BA, Corrada MM, Kawas CH 2009 High levels of serum C-reactive protein are associated with greater risk of all-cause mortality, but not dementia, in the oldest-old: results from the 90+ study. J Am Geriatr Soc 57:641-646
32. Danesh J, Pepys MB 2009 C-reactive protein and coronary disease: is there a causal link? Circulation 120:2036-2039
33. Elliott P, Chambers JC, Zhang W, Clarke R, Hopewell JC, Peden JF, Erdmann J, Braund P, Engert JC, Bennett D, Coin L, Ashby D, Tzoulaki I, Brown IJ, Mt-Isa S, McCarthy MI, Peltonen L, Freimer NB, Farrall M, Ruokonen A, Hamsten A, Lim N, Froguel P, Waterworth DM, Vollenweider P, Waeber G, Jarvelin MR, Mooser V, Scott J, Hall AS, Schunkert H, Anand SS, Collins R, Samani NJ, Watkins H, Kooner JS 2009 Genetic loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA 302:37-48
34. Ridker PM 2007 Inflammatory biomarkers and risks of myocardial infarction, stroke, diabetes, and total mortality: implications for longevity. Nutr Rev 65(12 Pt 2):S253-S259
35. Gauldie J 2007 Inflammation and the aging process: devil or angel. Nutr Rev 65(12 Pt 2):S167-S169
36. Kanaya AM, Harris T, Goodpaster BH, Tylavsky F, Cummings SR; Health, Aging, and Body Composition (ABC) Study 2004 Adipocytokines attenuate the association between visceral adiposity and diabetes in older adults. Diabetes Care 27:1375-1380
37. Beasley LE, Koster A, Newman AB, Javaid MK, Ferrucci L, Kritchevsky SB, Kuller LH, Pahor M, Schaap LA, Visser M, Rubin SM, Goodpaster BH, Harris TB; Health ABC study 2009 Inflammation and race and gender differences in computerized tomography-measured adipose depots. Obesity (Silver Spring) 17:1062-1069
38. Rachoñ D 2005 Role of tumor necrosis factor (TNF) and interleukin-6 (IL-6) in the pathogenesis of late complications of menopause. effects of hormone replacement therapy on TNF and IL-6 expression. Pol Merkur Lekarski 18:724-727
39. Davison S, Davis SR 2003 New markers for cardiovascular disease risk in women: Impact of endogenous estrogen status and exogenous postmenopausal hormone therapy. J Clin Endocrinol Metab 88:2470-2478
40. Albert MA, Ridker PM 2006 C-reactive protein as a risk predictor: do race/ethnicity and gender make a difference? Circulation 114:e67-e74
41. Cushman M, Meilahn EN, Psaty BM, Kuller LH, Dobs AS, Tracy RP 1999 Hormone replacement therapy, inflammation, and hemostasis in elderly women. Arterioscler Thromb Vasc Biol 19:893-899
42. Ridker PM, Hennekens CH, Rifai N, Buring JE, Manson JE 1999 Hormone replacement therapy and increased plasma concentration of C-reactive protein. Circulation 100:713-716 (Pubitemid 29383640)