Opioid-induced hyperalgesia and tolerance

American Journal of Therapeutics

Volumn 17, Issue 5, 2010, Pages 498-510

  Bekhit, Mary Hanna ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

central sensitization; cholecystokinin; dynorphin; hyperalgesia; ketamine; neuroinflammation; neuronal plasticity; nitric oxide; NMDA; opioid; rostral ventromedial medulla; tolerance; tonic descending facilitation

Indexed keywords

ALFENTANIL; DESFLURANE; DYNORPHIN; FENTANYL; GLUTAMIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; KETAMINE; KETOBEMIDONE; METHADONE; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; OPIATE; PROGLUMIDE; PROTEIN KINASE C; REMIFENTANIL; TUMOR NECROSIS FACTOR ALPHA;

ABDOMINAL HYSTERECTOMY; ADVERSE DRUG REACTION; ALLODYNIA; ANESTHESIA INDUCTION; CALCIUM CELL LEVEL; CHRONIC PAIN; CLINICAL ASSESSMENT; COLON RESECTION; DRUG TOLERABILITY; ENCEPHALITIS; GENERAL ANESTHESIA; HUMAN; HYPERALGESIA; MEDULLA OBLONGATA; MESENCEPHALON; NEUROANATOMY; NEUROIMMUNOLOGY; OPIATE INDUCED HYPERALGESIA; PAIN ASSESSMENT; POSTANESTHESIA CARE; POSTOPERATIVE PAIN; PRIORITY JOURNAL; REVIEW; SENSITIZATION; SPINAL CORD; SPINOTHALAMIC TRACT; THALAMUS;

ANALGESICS, OPIOID; ANIMALS; CHOLECYSTOKININ; CLINICAL TRIALS AS TOPIC; DRUG EVALUATION, PRECLINICAL; DRUG TOLERANCE; DYNORPHINS; FENTANYL; HUMANS; HYPERALGESIA; KETAMINE; MORPHINE; NEUROIMMUNOMODULATION; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 77957789639     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e3181ed83a0     Document Type: Review

References (31)

1. Chang G, Chen L, Mao J. Opioid tolerance and hyper-algesia. Med Clin North Am. 2007;91:199-211.
2. Angst MS, Clark JD. Opioid-induced hyperalgesia, a qualitative systematic review. Anesthesiology. 2006;104: 570-587.
3. Ossipov MH, Lai J, King T, et al. Underlying mecha-nisms of pronociceptive consequences of prolonged morphine exposure. Biopolymers (Peptide Science). 2005; 80:319-324.
4. Richebe P, Rivat C, Laulin JP, et al. Ketamine improves the management of exaggerated postoperative pain observed in perioperative fentanyl-treated rats. Anesthesiology. 2005; 102:421-428.
5. Eisenach JC. Preemptive hyperalgesia, not analgesia? Anesthesiology. 2000;92:308-309.
6. Vanderah TW. Pathophysiology of pain. Med Clin North Am. 2007;91:1-12.
7. Ranney D. Anatomy of Pain. Ontario Inter-Urban Pain Conference, Waterloo, November 1996.
8. Chia YY, Liu K, Wang JJ, et al. Intraoperative high dose fentanyl induces postoperative fentanyl tolerance. Can J Anesth. 1999;46:872-877.
9. Guignard B, Bossard AE, Coste C, et al. Acute opioid tolerance: intraoperative remifentanil increases postoper-ative pain and morphine requirement. Anesthesiology. 2000;93:409-417.
10. Vanderah TW, Suenaga NMH, Ossipov MH, et al. Tonic descending facilitation from the rostral ventromedial medula mediates opioid-induced abnormal pain and antinociceptive tolerance. J Neurosci. 2001;21:279-286.
11. Celerier E, Laulin JP, Corcuff JB, et al. Progressive enhancement of delayed hyperalgesia induced by re-peated heroin administration: a sensitization process. J Neurosci. 2001;12:4074-4080.
12. Kissin I, Bright CA, Bradley EL. Acute tolerance to continuously infused alfentanil: the role of cholecystokinin and N-methyl-D-aspartate-nitric oxide systems. Anesth Analg. 2000;91:110-116.
13. Laulin JP Maurette P, Corcuff JB, et al. The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg. 2002;94:1263-1269.
14. Ossipov MH, Lai J, Vanderah TW, et al. Induction of pain facilitation by sustained opioid exposure: relation-ship to opioid antinociceptive tolerance. Life Sci. 2003;73: 783-800.
15. Mao J, Price DD, Mayer DJ. Thermal hyperalgesia in association with the development of morphine tolerance in rats: Roles of excitatory amino acid receptors and protein kinase C. J Neurosci. 1994;14:2301-2312.
16. Mao J. Opioid-induced abnormal pain sensitivity: impli-cations in clinical opioid therapy Pain. 2002;100: 213-217.
17. Fields HL, Bry J, Hentall I, et al. The activity of neurons in the rostral medulla of the rat during withdrawal from noxious heat. J Neurosci. 1983;3:2545-2552.
18. Fields HL, Heinricher MM, Mason P. Neurotransmitters in nociceptive modulatory circuits. Annu Rev Neurosci. 1991;14:219-245.
19. Kaplan H, Fields HL. Hyperalgesia during acute opioid abstinence: evidence for a nociceptive facilitating function of the rostral ventromedial medulla. J Neurosci. 1991;11: 1433-1439.
20. Morgan MM, Fields HL. Pronounced changes in the activity of nociceptive modulatory neurons in the rostral ventromedial medulla in response to prolonged thermal noxious stimuli. J Neurophysiol. 1994;72:1161-1170.
21. Mao J, Price DD, Mayer DJ. Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions. Pain. 1995;62:259-274.
22. Larcher A, Laulin JP, Celerier E, et al. Acute tolerance associated with a single opiate administration: involve-ment of N-methyl-D-aspartate-dependent pain facilitatory systems. Neuroscience. 1998;84:583-589.
23. Celerier E, Laulin J, Larcher A, et al. Evidence for opiate-activated NMDA processes masking opiate analgesia in rats. Brain Res. 1999;847:18-25.
24. Celerier E, Rivat C, Jun Y, et al. Long-lasting hyperalgesia induced by fentanyl in rats: Preventive effect of ketamine. Anesthesiology. 2000;92:465-472.
25. Chen L, Huang LM. Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature. 1992;356:521-523.
26. Simonnet G, Rivat C. Opioid-induced hyperalgesia: abnormal or normal pain? Neuroreport. 2003;14:1-7.
27. Kissin I, Bright CA, Bradley EL. The effect of ketamine on opioid-induced acute tolerance: can it explain reduction of opioid consumption with ketamine-opioid analgesic combinations? Anesth Analg. 2000;91:1483-1488.
28. Bilsky EJ, Inturrisi CE, Sadée W, et al. Competitive and non-competitive NMDA antagonists block the develop-ment of antinociceptive tolerance to morphine, but not to selective μ or δ opioid agonists in mice. Pain. 1996;68: 229-237.
29. Toda N, Kishioka S, Hatano Y, et al. Modulation of opioid actions by nitric oxide signaling. Anesthesiology. 2009;110: 166-181.
30. Li X, Clark JD. Hyperalgesia during opioid abstinence: mediation by glutamate and substance p. Anesth Analg. 2002;95:979-984.
31. De Leo JA, Tanga FY, Tawfik VL. Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist. 2004;10:4052.