Competitive and non-competitive NMDA antagonists block the development of antinociceptive tolerance to morphine, but not to selective μ or δ opioid agonists in mice

Pain

Volumn 68, Issue 2-3, 1996, Pages 229-237

  Bilsky, Edward J ^a   Inturrisi, Charles E ^b   Sadée, Wolfgang ^c   Hruby, Victor J ^a   Porreca, Frank ^a,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

Author keywords

receptors; receptors; antinociceptive tolerance; LY235959; mice; MK801; N methyl D aspartate antagonists; opioids; swim stress

Indexed keywords

DECAHYDRO 6 PHOSPHONOMETHYL 3 ISOQUINOLINECARBOXYLIC ACID; DELTA OPIATE RECEPTOR; DIZOCILPINE; MORPHINE; MU OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; OPIATE; OPIATE AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG TOLERANCE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ANALGESICS, OPIOID; ANIMALS; BINDING, COMPETITIVE; DIZOCILPINE MALEATE; DRUG TOLERANCE; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; EXCITATORY AMINO ACID ANTAGONISTS; FENTANYL; ISOQUINOLINES; MALE; MICE; MICE, INBRED ICR; MORPHINE; OLIGOPEPTIDES; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU;

EID: 0030444685     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(96)03185-5     Document Type: Article

References (38)

1. Abdelhamid, E.E., Sultana, M., Portoghese, P.S. and Takemori, A.E., Selective blockade of delta opioid receptors prevents the development of morphine tolerance and dependence in mice, J. Pharmacol. Exp. Ther., 258 (1991) 299-303.
2. Adams, J.U., Paronis, C.A. and Holtzman, S.G., Assessment of relative intrinsic activity of mu-opioid analgesics in vivo by using β-funaltrexamine, J. Pharmacol. Exp. Ther., 255 (1990) 1027-1032.
3. Arden, J.R., Segredo, V., Wang, Z., Lameh, J. and Sadée,W., Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged μ-opioid receptor expressed in HEK 293 cells, J. Neurochem., 65 (1995) 1636-1645.
4. Bhargava, H.N. and Thorat, S.N., Effect of dizocilpine (MK-801) on analgesia and tolerance induced by U-50,488H, a κ-opioid receptor agonist, in the mouse, Brain Res., 649 (1994) 111-116.
5. Bilsky, E.J., Bernstein, R.N., Wang, Z.J., Sadée, W. and Porreca, F., Effects of neutral and negative antagonists and protein kinase inhibitors on acute morphine dependence and antinociceptive tolerance in mice, J. Pharmacol. Exp. Ther., 277 (1996) 484-490.
6. Chang, K.-J., Wei, E.T., Killian, A. and Chang, J.-K., Potent morphiceptin analogs: structure activity relationships and morphine-like activities, J. Pharmacol. Exp. Ther., 227 (1983) 403-408.
7. Chen, L. and Huang, L.-Y.M., Sustained potentiation of NMDA receptor mediated glutamate responses through activation of protein kinase C by a μ opioid, Neuron, 7 (1991) 319-326.
8. Elliott, K., Minami, N., Kolesnikov, Y.A., Pasternak, G.W. and Inturrisi, C.E., The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids, Pain, 56 (1994) 69-75.
9. Emmerson, P.J., Liu, M.R., Woods, J.H. and Medzihradsky, F., Binding affinity and selectivity of opioids at mu, delta and kappa receptors in monkey brain membranes, J. Pharmacol. Exp. Ther., 271 (1994) 1630-1637.
10. Favaron, M., Manev, H., Alho, H., Bertolino, M., Ferret, B., Guidotti, A. and Costa, E., Gangliosides prevent glutamate neurotoxicity in neuronal cultures, Proc. Natl. Acad. Sci. USA, 85 (1988) 7351-7355.
11. Foley, K.M., Clinical tolerance to opioids. In: A.I. Basbaum and J.M. Besson (Eds.), Towards a New Pharmacotherapy of Pain, Wiley, Chicester, 1991, pp. 181-204.
12. Handa, B.K., Lane, A.C., Lord, J.A.H., Morgan, B.A., Rance, M.J. and Smith, C.F.C., Analouges of B-LPH61-64 possessing selective agonist activity at mu-opiate receptors, Eur. J. Pharmacol., 70 (1981) 531-540.
13. Horan, P.J. and Ho, I.K., Comparative pharmacological studies between butorphanol and morphine, Pharmacol. Biochem. Behav., 34 (1989) 847-854.
14. Inturrisi, C.E., Opioid analgesic therapy in cancer pain. In: K.M. Foley, J.J. Bonica and V. Ventafridda (Eds.), Advances in Pain Research and Therapy, Raven Press, New York, 1990, pp. 133-154.
15. 2]deltorphin II, a highly selective δ agonist in vivo. Life Sci., 47 (1990) PL43-PL47.
16. Kennedy, C. and Henderson, G., Mu-opioid receptor inhibition of calcium current: development of homologous tolerance in single SH-SY5Y cells after chronic exposure to morphine in vitro, Mol. Pharmacol., 40 (1991) 1000-1005.
17. Kest, B., Lee, C.E., McLemore, G.L. and Inturrisi, C.E., An antisense oligodeoxynucleotide to the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice, Brain Res., (1996) in press.
18. Kolesnikov, Y.A., Pick, C.G., Ciszewska, G. and Pasternak, G.W., Blockade of tolerance to morphine but not kappa opioids by a nitric oxide synthase inhibitor, Proc. Natl. Acad. Sci. USA, 90 (1993) 5162-5166.
19. Kramer, T.H., Davis, P., Hruby, V.J., Burks, T.H. and Porreca, F., In vitro potency, affinity and agonist efficacy of highly selective delta opioid receptor ligands, J. Pharmacol. Exp. Ther., 266 (1993) 577-584.
20. Magal, E., Louis, J.C., Aguilera, J. and Yavin, E., Gangliosides prevent ischemia-induced down-regulation of protein kinase C in fetal rat brain, J. Neurochem., 55 (1990) 2126-2131.
21. Maguire, P., Tsai, N., Kamal, J., Cometta-Morini, C., Upton, C. and Loew, G., Pharmacological profiles of fentanyl analogs at μ, δ and κ opiate receptors, Eur. J. Pharmacol., 213 (1992) 219-225.
22. Mao, J., Price, D.D. and Mayer, D.J., Mechanisms of hyperalgesia and morphine tolerance: a current view of their possible interactions, Pain, 62 (1995a) 259-274.
23. Mao, J., Price, D.D., Phillips, L.L., Lu, J. and Mayer, D.J., Increases in protein kinase C gamma immunoreactivity in the spinal cord of rats associated with tolerance to the analgesic effects of morphine, Brain Res., 677 (1995b) 257-267.
24. Marek, P., Shamgar, B-E, Gold, M. and Liebeskind, J.C., Excitatory amino acid antagonists (kynurenic acid and MK-801) attenuate the development of morphine tolerance in the rat, Brain Res., 547 (1991) 77-81.
25. 2]deltorphin II in mice: evidence for delta receptor subtypes, J. Pharmacol. Exp. Ther., 258 (1991) 583-587.
26. Mayer, D.J., Mao, J. and Price, D.D., The development of morphine tolerance and dependence is associated with translocation of protein kinase C, Pain, 61 (1995) 365-374.
27. Mignat, C., Wille, U. and Ziegler, A., Affinity profiles of morphine, codeine, dihydrocodeine and their glucoronides at opioid receptor subtypes, Life Sci., 56 (1995) 793-799.
28. Miller, L., Shaw, J.S. and Whiting, E.M., The contribution of intrinsic activity to the action of opioids in vitro, Br. J. Pharmacol., 87 (1986) 595-601.
29. Mjanger, E. and Yaksh, T.L., Characteristics of dose-dependent antagonism by beta-funaltrexamine of the antinociceptive effects of intrathecal mu agonists, J. Pharmacol. Exp. Ther., 258 (1984) 544-550.
30. Porreca, F., Mosberg, H.I., Hurst, R., Hruby, V.J. and Burks, T.F., Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse, J. Pharmacol. Exp. Ther., 230 (1984) 341-348.
31. Sadée, W., Wang, Z., Arden, J.R. and Segredo, V., Constitutive activation of the μ-opioid receptor: a novel paradigm of receptor regulation in narcotic analgesia, tolerance, and dependence, Analgesia, 1 (1994) 11-14.
32. Tiseo, P.J. and Inturrisi, C.E., Attenuation and reversal of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist, LY274614, J. Pharmacol. Exp. Ther., 264 (1994) 1090-1096.
33. Trujillo, K. A. and Akil, H., Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801, Science, 251 (1991) 85-87.
34. Tsou, K., Snyder, G.L. and Greengard, P., Nitric oxide/cGMP pathway stimulates phosphorylation of DARP-32, a dopamine- and cAMP-regulated phosphoprotein, in the substantia nigra, Proc. Natl. Acad. Sci. USA, 90 (1993) 3462-3465.
35. Vaccarino, F., Guidotti, A. and Costa, E., Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons, Proc. Natl. Acad. Sci. USA, 34 (1987) 8707-8711.
36. Wang, Z., Bilsky, E.J., Porreca, F. and Sadée, W., Constitutive μ opioid receptor activation as a regulatory mechanism underlying narcotic tolerance and dependence, Life Sci., 54PL (1994) 339-350.
37. Way, E.L., Loh, H.H. and Shen, F-H., Simultaneous quantitative assessment of morphine tolerance and physical dependence, J. Pharmacol. Exp. Ther., 167 (1969) 1-8.
38. Welch, S.P. and Olson, K.G., Opiate tolerance-induced modulation of free intracellular calcium in synaptosomes, Life Sci., 48 (1991) 1853-1861.