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Volumn 226, Issue 1, 2010, Pages 15-23

Effect of thalidomide and pentoxifylline on experimental autoimmune encephalomyelitis (EAE)

Author keywords

EAE; Multiple sclerosis; Nitric oxide; Pentoxifylline; Thalidomide; TNF alpha and Interferongamma

Indexed keywords

GAMMA INTERFERON; NITRIC OXIDE; PENTOXIFYLLINE; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA; IMMUNOSUPPRESSIVE AGENT; PHOSPHODIESTERASE INHIBITOR;

EID: 77957759989     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.04.007     Document Type: Article
Times cited : (19)

References (33)
  • 2
    • 0018644086 scopus 로고
    • Approaches to the treatment of central nervous system autoimmune disease
    • Alvord E.C., Shaw C.M., Hruby S. Approaches to the treatment of central nervous system autoimmune disease. Ann. Neurol. 1979, 6:469-473.
    • (1979) Ann. Neurol. , vol.6 , pp. 469-473
    • Alvord, E.C.1    Shaw, C.M.2    Hruby, S.3
  • 3
    • 33646903671 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-γ
    • Balabanov R., Strand K., Kemper A., Lee J.Y., Popko B. Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-γ. J. Neurosci. 2006, 26(19):5143-5152.
    • (2006) J. Neurosci. , vol.26 , Issue.19 , pp. 5143-5152
    • Balabanov, R.1    Strand, K.2    Kemper, A.3    Lee, J.Y.4    Popko, B.5
  • 4
    • 0031569219 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis
    • Brenner T., Brocke S., Szafer F., Sobel R.A., Parkinson J.F., Perez D.H., Steinman L. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis. J. Immunol. 1997, 158(6):2940-2946.
    • (1997) J. Immunol. , vol.158 , Issue.6 , pp. 2940-2946
    • Brenner, T.1    Brocke, S.2    Szafer, F.3    Sobel, R.A.4    Parkinson, J.F.5    Perez, D.H.6    Steinman, L.7
  • 5
    • 77957796197 scopus 로고    scopus 로고
    • Encefalomielite Autoimune Experimental. Importância da expressão de fibronectina no desenvolvimento das lesões. Dissertação (Mestrado em Patologia Experimental) - Universidade Federal Fluminense
    • Carvalho, M.C.A., 1999. Encefalomielite Autoimune Experimental. Importância da expressão de fibronectina no desenvolvimento das lesões. 132 p. Dissertação (Mestrado em Patologia Experimental) - Universidade Federal Fluminense.
    • (1999) , pp. 132
    • Carvalho, M.C.A.1
  • 6
    • 0031846669 scopus 로고    scopus 로고
    • Interaction of thalidomide, thalidomide analogues of thalidomide and pentoxifylline with the anti-tumor agent 5, 6-dimethylxanthenone-4-acet acid: concomitant reduction of serum tumor necrosis factor-alpha and enhancement of anti-tumor activity
    • Ching L.M., Browne W.L., Tchernegovski R., Gregory T., Baguley B.C., Palmer B.D. Interaction of thalidomide, thalidomide analogues of thalidomide and pentoxifylline with the anti-tumor agent 5, 6-dimethylxanthenone-4-acet acid: concomitant reduction of serum tumor necrosis factor-alpha and enhancement of anti-tumor activity. Brit. J. Can. 1998, 78(3):336-343.
    • (1998) Brit. J. Can. , vol.78 , Issue.3 , pp. 336-343
    • Ching, L.M.1    Browne, W.L.2    Tchernegovski, R.3    Gregory, T.4    Baguley, B.C.5    Palmer, B.D.6
  • 7
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production
    • Ding A., Nathan C.F., Stuer D.J. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages: comparison of activating cytokines and evidence for independent production. J. Immunol. 1988, 141:2407-2503.
    • (1988) J. Immunol. , vol.141 , pp. 2407-2503
    • Ding, A.1    Nathan, C.F.2    Stuer, D.J.3
  • 8
    • 34248355132 scopus 로고    scopus 로고
    • Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models
    • Fabis M.J., Scott G.S., Kean R.B., Koprowski H., Hooper D.C. Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models. Proc. Natl. Acad. Sci. 2007, 104(13):5656-5661.
    • (2007) Proc. Natl. Acad. Sci. , vol.104 , Issue.13 , pp. 5656-5661
    • Fabis, M.J.1    Scott, G.S.2    Kean, R.B.3    Koprowski, H.4    Hooper, D.C.5
  • 9
    • 33845662118 scopus 로고    scopus 로고
    • Oral tolerance: therapeutic implications for autoimmune diseases
    • Faria A.M., Weiner H.l. Oral tolerance: therapeutic implications for autoimmune diseases. Clin. Dev. Immunol. 2006, 13(2-4):143-157.
    • (2006) Clin. Dev. Immunol. , vol.13 , Issue.2-4 , pp. 143-157
    • Faria, A.M.1    Weiner, H.2
  • 11
    • 37149001297 scopus 로고    scopus 로고
    • Natalizumab em el tratamiento de la esclerosis múltiple
    • Horga A., Horga J.F. Natalizumab em el tratamiento de la esclerosis múltiple. Rev. Neurol. 2007, 45(5):293-303.
    • (2007) Rev. Neurol. , vol.45 , Issue.5 , pp. 293-303
    • Horga, A.1    Horga, J.F.2
  • 12
    • 29744437714 scopus 로고    scopus 로고
    • Copolymer effects on microglia and T cells in the central nervous system of humanized mice
    • Illes Z., Stern J.N., Keskin D.B., Reddy J., Brosnan C.F., Waldner H., et al. Copolymer effects on microglia and T cells in the central nervous system of humanized mice. Eur. J. Immunol. 2005, 35:3683-3693.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 3683-3693
    • Illes, Z.1    Stern, J.N.2    Keskin, D.B.3    Reddy, J.4    Brosnan, C.F.5    Waldner, H.6
  • 13
    • 0028806468 scopus 로고
    • Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β
    • Issazadeh S., Ljungdahl A., Höjeberg B., Mustafa M., Olsson T. Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factorβ. J. Neuroimmunol. 1995, 61:205-212.
    • (1995) J. Neuroimmunol. , vol.61 , pp. 205-212
    • Issazadeh, S.1    Ljungdahl, A.2    Höjeberg, B.3    Mustafa, M.4    Olsson, T.5
  • 15
    • 77957806282 scopus 로고    scopus 로고
    • Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models. Exp. Neu. Mon. Oct 19
    • Lassmann, H., 2009. Axonal and neuronal pathology in multiple sclerosis: what have we learnt from animal models. Exp. Neu. Mon. Oct 19.
    • (2009)
    • Lassmann, H.1
  • 16
    • 0018422657 scopus 로고
    • Chronic relapsing experimental allergic encephalomyelitis: clinicopathological comparison with multiple sclerosis
    • Lassmann H., Wisniewski H.M. Chronic relapsing experimental allergic encephalomyelitis: clinicopathological comparison with multiple sclerosis. Arch. Neurol. 1979, 36(490):1979.
    • (1979) Arch. Neurol. , vol.36 , Issue.490 , pp. 1979
    • Lassmann, H.1    Wisniewski, H.M.2
  • 17
    • 0031802996 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide
    • Leadbetter E.A., Bourque C.R., Devaux B., Olson C.D., Sunshine G.H., Hirani S., et al. Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide. J. Immunol. 1998, 161(1):504-512.
    • (1998) J. Immunol. , vol.161 , Issue.1 , pp. 504-512
    • Leadbetter, E.A.1    Bourque, C.R.2    Devaux, B.3    Olson, C.D.4    Sunshine, G.H.5    Hirani, S.6
  • 18
    • 0026751291 scopus 로고
    • Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells
    • Macmicking J.D., Willenborg D.O., Weidemann M.J., Rockett K.A., Cowden W.B. Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells. J. Exp. Med. 1992, 176(1):303-307.
    • (1992) J. Exp. Med. , vol.176 , Issue.1 , pp. 303-307
    • Macmicking, J.D.1    Willenborg, D.O.2    Weidemann, M.J.3    Rockett, K.A.4    Cowden, W.B.5
  • 19
    • 77957771565 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia
    • A 10
    • Melanson M., Miao P., Eisenstat D., Gong Y., Gu X., Au K., Zhu W., Begum F., Frost E., Namaka M. Experimental autoimmune encephalomyelitis-induced upregulation of tumor necrosis factor-alpha in the dorsal root ganglia. Mult. Scler. Aug 10 2009, 3:22-35.
    • (2009) Mult. Scler. , vol.3 , pp. 22-35
    • Melanson, M.1    Miao, P.2    Eisenstat, D.3    Gong, Y.4    Gu, X.5    Au, K.6    Zhu, W.7    Begum, F.8    Frost, E.9    Namaka, M.10
  • 20
    • 2342634246 scopus 로고    scopus 로고
    • The use of digital technology to assess the severity of the experimental allergic encephalomyelitis (EAE) spinal cord lesion
    • Mohamed A., Tarhuni H., Dufan T., Benghuzzi H., Tucci M. The use of digital technology to assess the severity of the experimental allergic encephalomyelitis (EAE) spinal cord lesion. Biomed. Sci. Instrum. 2004, 40:419-423.
    • (2004) Biomed. Sci. Instrum. , vol.40 , pp. 419-423
    • Mohamed, A.1    Tarhuni, H.2    Dufan, T.3    Benghuzzi, H.4    Tucci, M.5
  • 21
    • 0034198767 scopus 로고    scopus 로고
    • Multiple sclerosis: descriptive study of its clinical forms in 302 cases
    • Moreira M.A., Felipe E., Mendes M.F., Tilbery C.P. Multiple sclerosis: descriptive study of its clinical forms in 302 cases. Arq. Neuropsiquiatr. 2000, 58(2-B):460-466.
    • (2000) Arq. Neuropsiquiatr. , vol.58 , Issue.2 B , pp. 460-466
    • Moreira, M.A.1    Felipe, E.2    Mendes, M.F.3    Tilbery, C.P.4
  • 22
    • 0025059497 scopus 로고    scopus 로고
    • Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality
    • Noel P., Nelson S., Bokulic R., Bagby G., Lippton H., Lipscomb G., Summer W. Pentoxifylline inhibits lipopolysaccharide-induced serum tumor necrosis factor and mortality. Life Sci. 1998, 47:1023-1029.
    • (1998) Life Sci. , vol.47 , pp. 1023-1029
    • Noel, P.1    Nelson, S.2    Bokulic, R.3    Bagby, G.4    Lippton, H.5    Lipscomb, G.6    Summer, W.7
  • 23
    • 35148835215 scopus 로고    scopus 로고
    • CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells
    • Ponomarev Ed., Maresz K., Tan Y., Dittel B.N. CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells. J. Neurosci. 2007, 3;27(40):10714-10721.
    • (2007) J. Neurosci. , Issue.40 , pp. 10714-10721
    • Ponomarev, E.1    Maresz, K.2    Tan, Y.3    Dittel, B.N.4
  • 25
    • 0029316962 scopus 로고
    • Experimental autoimmune encephalomyelitis: immunotherapy with anti-tumor necrosis factor antibodies and soluble tumor necrosis factor receptors
    • Selmaj K.W., Raine C.S. Experimental autoimmune encephalomyelitis: immunotherapy with anti-tumor necrosis factor antibodies and soluble tumor necrosis factor receptors. Neurology 1995, 45(6 Suppl (6):S44-S49.
    • (1995) Neurology , vol.45 , Issue.6 SUPPL. 6
    • Selmaj, K.W.1    Raine, C.S.2
  • 26
    • 0006039497 scopus 로고    scopus 로고
    • Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis
    • Seungjoon Kim, Changjong M., Myung B.W., Hyungmin K., Naoyuki T., Yoh M., Taekyun S. Enhanced expression of constitutive and inducible forms of nitric oxide synthase in autoimmune encephalomyelitis. J. Vet. Sci. 2000, 1(1):11-17.
    • (2000) J. Vet. Sci. , vol.1 , Issue.1 , pp. 11-17
    • Seungjoon, K.1    Changjong, M.2    Myung, B.W.3    Hyungmin, K.4    Naoyuki, T.5    Yoh, M.6    Taekyun, S.7
  • 28
    • 33645518677 scopus 로고    scopus 로고
    • Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity
    • Stüve O., Youssef S., Weber M.S., Nessler S., Von Büdingen H.C., Hemmer B., et al. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. J. Clin. Invest. 2006, 116(4):1037-1044.
    • (2006) J. Clin. Invest. , vol.116 , Issue.4 , pp. 1037-1044
    • Stüve, O.1    Youssef, S.2    Weber, M.S.3    Nessler, S.4    Von Büdingen, H.C.5    Hemmer, B.6
  • 33
    • 34548048635 scopus 로고    scopus 로고
    • Sinomenine, an antirheumatic alkaloid, ameliorates clinical signs of disease in the Lewis rat model of acute experimental autoimmune encephalomyelitis
    • Yanying Z., Bingjie G., Xiaohui J., Xinsheng D., Chunjie S., Feichi W. Sinomenine, an antirheumatic alkaloid, ameliorates clinical signs of disease in the Lewis rat model of acute experimental autoimmune encephalomyelitis. Biol. Pharm. Bull. 2007, 30(8):1438-1444.
    • (2007) Biol. Pharm. Bull. , vol.30 , Issue.8 , pp. 1438-1444
    • Yanying, Z.1    Bingjie, G.2    Xiaohui, J.3    Xinsheng, D.4    Chunjie, S.5    Feichi, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.