The effect of lead on bone mineral properties from female adult C57/BL6 mice

Bone

Volumn 47, Issue 5, 2010, Pages 888-894

  Monir, A U ^a   Gundberg, C M ^b   Yagerman, S E ^c   van der Meulen, M C H ^c,d   Budell, W C ^a   Boskey, A L ^d   Dowd, T L ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c School of Operations Research and Industrial Engineering   (United States)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Biomarkers; Bone; Fourier Transform Infrared Imaging; Lead; Mice; Microcomputed tomography

Indexed keywords

AMINO TERMINAL TELOPEPTIDE; BIOLOGICAL MARKER; COLLAGEN; DRINKING WATER; LEAD; OSTEOCALCIN;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MINERAL; BONE STRENGTH; BONE TURNOVER; CANCELLOUS BONE; CONTROLLED STUDY; CORTICAL BONE; FEMALE; FEMUR; MICRO-COMPUTED TOMOGRAPHY; MICROSCOPY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; PROTEIN BLOOD LEVEL; TRABECULAR BONE;

ANIMALS; BIOMECHANICS; BONE DENSITY; CALCIFICATION, PHYSIOLOGIC; FEMALE; LEAD; MICE; MICE, INBRED C57BL; ORGANOMETALLIC COMPOUNDS; OSTEOCALCIN; OSTEOPOROSIS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; X-RAY MICROTOMOGRAPHY;

EID: 77957756432     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2010.07.013     Document Type: Article

References (46)

1. Pirkle J.L., Kaufmann R.B., Brody D.J., Hickman T., Gunter E.W., Paschal D.C. Exposure of the U.S. population to lead, 1991-1994. Environ Health Perspect 1998, 106:745-750.
2. Canfield R.L., Henderson C.R., Cory-Slechta D.A., Cox C., Jusko T.A., Lanphear B.P. Intellectual impairment in children with blood lead concentrations below 10microgram per deciliter. N Engl J Med 2003, 348:1517-1526.
3. Barry P.S.I. Concentrations of lead in the tissues of children. Br J Ind Med 1981, 38:61-71.
4. Barry P.S.I. A comparison of concentrations of lead in human tissues. Br J Ind Med 1975, 32:119-139.
5. Rosen J.F., Markowitz M.E., Bijur P.E., Jenks S.T., Wielopolski L., Kalef-Ezra J.A., et al. L-line X-ray fluorescence of cortical bone lead compared with the CaNa2EDTA test in lead-toxic children: public health implications. Proc Natl Acad Sci 1989, 86:685-689.
6. Bleeker M.L., McNeil F.E., Lindgren K.N., Masten V.L., Ford D.P. Relationship between bone lead and other indices of lead exposure in smelter workers. Toxicol Lett 1995, 77:241-248.
7. Kim R., Landrigan C., Mossmann P., Sparrow D., Hu H. Age and secular trends in bone lead levels in middle-aged and elderly men: three year longitudinal follow-up in the normative aging study. Am J Epidemiol 1997, 146:586-591.
8. Skerfving S., Nilsson U. Assessment of accumulated body burden of metals. Toxicol Lett 1992, 64/65:17-24.
9. Gamblin C., Gordon C.L., Meir D.C.F., Chettle D.R., Webber C.E. In-vivo measurements of bone lead content in residents of Southern Ontario. Appl Radiat Isot 1994, 45:1035-1038.
10. Vig E.K., Hu H. Lead toxicity in older adults. J Am Geriatr Soc 2000, 48:1501-1506.
11. Long G.J., Rosen J.F., Pounds J.G. Lead impairs the production of osteocalcin by rat osteosarcoma (ROS 17/2.8) cells. Toxicol Appl Pharmacol 1990, 106:270-277.
12. Angle C.R., Thomas D.J., Swanson S.A. Lead inhibits the basal and stimulated responses of rat osteoblast-like cell line ROS 17/2.8 to 1α, 25-dihydroxyvitamin D3 and IGF-I. Toxicol Appl Pharmacol 1990, 103:281-287.
13. Hicks D.G., O'Keefe R.J., Reynolds K.J., Cory-Schlecta D.A., Puzas J.E., Judkins A., et al. Effect of lead on growth plate chondrocyte phenotype. Toxicol Appl Pharmacol 1996, 140:164-172.
14. Zuscik M.J., Pateder D.B., Puzas J.E., Schwarz E.M., Rosier R.N., O'Keefe R.J. Lead alters parathyroid hormone-related peptide and transforming growth factor-β1 effects and AP-1 and NF-κB signaling in chondrocytes. J Orthop Res 2002, 20:811-818.
15. Miyahara T., Koniyama H., Miyanishi A., Takata M., Nagai M., Kozuka H., et al. Stimulative effects of lead on bone resorption in organ culture. Toxicology 1995, 97:191-197.
16. Schwartz J., Angle C., Pitcher H. Relationship between childhood blood lead levels and stature. Pediatrics 1986, 77:281-288.
17. Shukla R., Bornschein R.L., Dietrich K.N., Buncher C.R., Berger O., Hammond P.B., et al. Effects of fetal and infant lead exposure on growth in stature. Pediatrics 1989, 84:604-612.
18. Hass G.M., Brown D.V.L., Eisenstein R., Hemmens A. Relations between lead poisoning in rabbit and man. Am J Pathol 1964, 5:691-727. XLV.
19. Escribano A., Revilla M., Hernández E.R., Seco C., González-Riola J., Villa L.F., et al. Effect of lead on bone development and bone mass: a morphometric, densitometric, and histomorphometric study in growing rats. Calcif Tissue Int 1997, 60:202-203.
20. Hamilton J.D., O'Flaherty E.J. Effects of lead exposure on skeletal development in rats. Fundam Appl Toxicol 1994, 22:594-604.
21. Carmouche J.J., Puzas J.E., Zhang X., Tiyapatanaputi P., Cory-Slechta D.A., Gelein R., et al. Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environ Health Perspect 2005, 113:749-755.
22. Khalil N., Cauley J.A., Wilson J.W., Talbott E.O., Morrow L., Hochberg M.C., et al. Relationship of blood lead levels to incident nonspine fractures and falls in older women: the study of osteoporotic fractures. J Bone Miner Res 2008, 23:1417-1425.
23. Gruber H.E., Gonick H.C., Khalil-Manesh F., Sanchez T.V., Motsinger S., Meyer M., et al. Osteopenia induced by long-term, low- and high-level exposure of the adult rat to lead. Miner Electrolyte Metab 1997, 23:65-73.
24. Gruber H.E., Ding Y., Stasky A.A., Meyer M., Pandian M.R., Pandian D., et al. Adequate dietary calcium mitigates osteopenia induced by chronic lead exposure in adult rats. Miner Electrolyte Metab 1999, 25:143-146.
25. Massie H.R., Aiello V.R. Lead accumulation in the bones of aging male mice. Gerontology 1992, 38:13-17.
26. Beamer W.G., Donahue L.R., Rosen C.J., Baylink D.J. Genetic variability in adult bone density among inbred strains of mice. Bone 1996, 18:397-403.
27. Gundberg C.M., Hauschka P.V., Lian J.B., Gallop P.M. Osteocalcin: isolation, characterization, and detection. Meth Enzymol 1984, 107:516-544.
28. Hale L.V., Sells Galvin R.J., Risteli J., Ma Y.L., Harvey A.K., Yang X., et al. PINP: a serum biomarker of bone formation in the rat. Bone 2007, 40:1103-1109.
29. Garnero P., Ferreras M., Karsdal M.A., Nicamhlaoibh R., Risteli J., Borel O., et al. The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation. J Bone Miner Res 2003, 18:859-867.
30. Paschalis E.P., Verdelis K., Mendelsohn R., Boskey A., Yamauchi M. Spectroscopic determination of collagen cross-links in bone. J Bone Miner Res 2001, 16:1821-1828.
31. Mendelsohn R., Paschalis E.P., Boskey A.L. Infrared spectroscopy, microscopy, and microscopic imaging of mineralizing tissues. Spectra-structure correlations from human iliac crest biopsies. J Biomed Opt 1999, 4:14-21.
32. Miyake M., Ishigaki K., Suzuki T. Structure refinements of Pb2+ ion-exchanged apatites by X-ray powder pattern-fitting. J Sol State Chem 1986, 61:230-235.
33. Christoffersson J.O., Schutz A., Skerfving S., Ahlgren L., Mattsson S. A model describing the kinetics of lead in occupationally exposed workers. In vivo body composition studies 1987, 334-347. Institute of Physical Sciences in Medicine, London, England. K.T. Ellis, S. Yasumura, W.D. Morgan (Eds.).
34. C. Rubin, J. Rubin, Biomechanics and Mechanobiology of Bone. In: MJ Favus (ed.) Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 6th ed. American Society for Bone and Mineral Research, Washington DC, USA, 2006, pp. 36-41.
35. Currey J.D. The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone. J Biomech 1988, 21(2):131-139.
36. Yerramshetty J.S., Akkus O. The associations between mineral crystallinity and the mechanical properties of human cortical bone. Bone 2008, 42:476-482.
37. Wang X., Li X., Bank R.A., Agrawal C.M. Effects of collagen unwinding and cleavage on the mechanical integrity of the collagen network in bone. Calcif Tissue Int 2002, 71:186-192.
38. Oxlund H., Berckman M., Ortoft G., Anderson T.T. Reduced concentrations of collagen cross-links are associated with reduced strength of bone. Bone 1995, 17:365S-371S.
39. Knott L., Whitehead C.C., Fleming R.H., Bailey A.J. Biochemical changes in the collagenous matrix of osteoporotic avian bone. Biochemistry 1995, 310:1045-1051.
40. Weinstein R.S. Perspective: true strength. J Bone Miner Res 2000, 15:621.
41. Lloyd S.A., Yuan Y.Y., Kostenuik P.J., Ominsky M.S., Lau A.G., Morony S., et al. RANKL induces high bone turnover and decreases bone volume, density, and strength in mice. Calcif Tissue Int 2008, 82:361-372.
42. Miyahara T., Komiyama H., Miyanishi A., Matsumoto M., Xue-Ya W., Takata M., et al. Effects of lead on osteoclast-like cell formation in mouse bone marrow cell cultures. Calcif Tissue Int 1994, 54:165-169.
43. Schanne F.A.X., Dowd T.L., Gupta R.K., Rosen J.F. Lead increases free Ca2+ concentration in cultured osteoblastic bone cells: simultaneous detection of intracellular free Pb2+ by 19F NMR. Proc Natl Acad Sci USA 1989, 86:5133-5135.
44. Zayzafoon M. Calcium/calmodulin signaling controls osteoblast growth and differentiation. J Cell Biochem 2006, 97:56-70.
45. Seales E.C., Micoli K.J., McDonald J.M. Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival. J Cell Biochem 2006, 97:45-55.
46. Silbergeld E.K., Schwartz J., Mahaffey Lead K. Lead and osteoporosis: mobilization of lead from bone in postmenopausal women. Environ Res 1988, 47:79-94.