Enhanced albumin synthesis in severely burned adults

Shock

Volumn 34, Issue 4, 2010, Pages 364-368

  Martini, Wenjun Z ^a   Wolf, Steven E ^a   Chinkes, David L ^b   Chung, Kevin K ^a   Dubick, Michael A ^a   Blackbourne, Lorne ^a   Yu, Yong Ming ^c  

^a US ARMY INSTITUTE OF SURGICAL RESEARCH   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Burn injury; gas chromatography and mass spectrometry; stable isotopes

Indexed keywords

2 OXOISOCAPROIC ACID; ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; FIBRINOGEN; GAMMA GLUTAMYLTRANSFERASE; LACTATE DEHYDROGENASE; PHENYLALANINE;

ADULT; ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; BREATHING RATE; BURN; CLINICAL ARTICLE; CONTROLLED STUDY; HEART RATE; HUMAN; MASS FRAGMENTOGRAPHY; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS;

ADULT; BURNS; CASE-CONTROL STUDIES; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MALE; SERUM ALBUMIN;

EID: 77957708712     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181d8844b     Document Type: Article

References (39)

1. Chen LW, Wang JS, Hwang B, Chen JS, Hsu CM: Reversal of the effect of albumin on gut barrier function in burn by the inhibition of inducible isoform of nitric oxide synthase. Arch Surg 138:1219-1225, 2003.
2. Gibbs J, Cull W, Henderson W, Daley J, Hur K, Khuri SF: Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the National VA Surgical Risk Study. Arch Surg 134:36-42, 1999.
3. Vincent JL, Navickis RJ, Wilkes MM: Morbidity in hospitalized patients receiving human albumin: a meta-analysis of randomized, controlled trials. Crit Care Med 32:2029-2038, 2004.
4. Belfrage S: Plasma protein pattern in course of acute infectious disease. Acta Med Scand 395:1-169, 1963.
5. Fleck A, Raines G, Hawker F, Trotter J, Wallace PI, Ledingham IM, Calman KC: Increased vascular permeability: a major cause of hypoalbuminaemia in disease and injury. Lancet 1:781-784, 1985.
6. Bonate PL: Pathophysiology and pharmacokinetics following burn injury. Clin Pharmacokinet 18:118-130, 1990.
7. Chinkes DL, Rosenblatt J, Wolfe RR: Assessment of the mathematical issues involved in measuring the fractional synthesis rate of protein using the flooding dose technique. Clin Sci (Lond) 84:177-183, 1993.
8. Debro JR, Korner A: Solubility of albumin in alcohol after precipitation by trichloroacetic acid: a simplified procedure for separation of albumin. Nature 178:1067, 1956.
9. Ballmer PE, Walshe D, McNurlan MA, Watson H, Brunt PW, Garlick PJ: Albumin synthesis rates in cirrhosis: correlation with Child-Turcotte classification. Hepatology (Baltimore, Md) 18:292-297, 1993.
10. Hunter KA, Garlick PJ, Broom I, Anderson SE, McNurlan MA: Effects of smoking and abstention from smoking on fibrinogen synthesis in humans. Clin Sci (Lond) 100:459-465, 2001.
11. Wolfe RR, Chinkes DL: Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis. 2nd ed. Hoboken, NJ: Jon WIley & Sons, Inc, 2005.
12. Yang E, Maguire T, Yarmush ML, Berthiaume F, Androulakis IP: Bioinfor-matics analysis of the early inflammatory response in a rat thermal injury model. BMC Bioinform 8:10, 2007.
13. Demant T, Mathes C, Gutlich K, Bedynek A, Steinhauer HB, Bosch T, Packard CJ, Warwick GL: A simultaneous study of the metabolism of apo-lipoprotein b and albumin in nephrotic patients. Kidney Int 54:2064-2080, 1998.
14. Sironi AM, Vichi S, Gastaldelli A, Pecori N, Anichini R, Foot E, Seghieri G, Ferrannini E: Effects of troglitazone on insulin action and cardiovascular risk factors in patients with non-insulin-dependent diabetes. Clin Pharmacol Ther 62:194-202, 1997.
15. Mansoor O, Cayol M, Gachon P, Boirie Y, Schoeffler P, Obled C, Beaufrere B: Albumin and fibrinogen syntheses increase while muscle protein synthesis decreases in head-injured patients. Am J Physiol 273:E898YE902, 1997.
16. Jackson AA, Phillips G, McClelland I, Jahoor F: Synthesis of hepatic secretory proteins in normal adults consuming a diet marginally adequate in protein. Am J Physiol 281:G1179YG1187, 2001.
17. Imoberdorf R, Garlick PJ, McNurlan MA, Casella GA, Peheim E, Turgay M, Bartsch P, Ballmer PE: Enhanced synthesis of albumin and fibrinogen at high altitude. J Appl Physiol 90:528-537, 2001.
18. Fleck A: Plasma proteins as nutritional indicators in the perioperative period. Br J Clin Pract 63:20-24, 1988.
19. De Feo P, Volpi E, Lucidi P, Cruciani G, Reboldi G, Siepi D, Mannarino E, Santeusanio F, Brunetti P, Bolli GB: Physiological increments in plasma insulin concentrations have selective and different effects on synthesis of hepatic proteins in normal humans. Diabetes 42:995-1002, 1993.
20. Mendez CM, McClain CJ, Marsano LS: Albumin therapy in clinical practice. Nutr Clin Pract 20:314-320, 2005.
21. Hart DW, Wolf SE, Chinkes DL, Gore DC, Mlcak RP, Beauford RB, Obeng MK, Lal S, Gold WF, Wolfe RR, et al.: Determinants of skeletal muscle catabolism after severe burn. Ann Surg 232:455-465, 2000.
22. Parving HP, Gyntelberg F: Transcapillary escape rate of albumin and plasma volume in essential hypertension. Circ res 32:643-651, 1973.
23. De Vries EG, Beekhuis H, De Jong R, Mulder NH, Piers DA: Evidence for capillary leakage during chemotherapy in man. Eur J Clin Invest 16:243-247, 1986.
24. Ballmer PE, Ochsenbein AF, Schutz-Hofmann S: Transcapillary escape rate of albumin positively correlates with plasma albumin concentration in acute but not in chronic inflammatory disease. Metabolism 43:697-705, 1994.
25. Grossman J, Yalow AA, Weston RE: Albumin degradation and synthesis as influenced by hydrocortisone, corticotropin and infection. Metabolism 9:528-550, 1960.
26. Ryan CM, Yarmush ML, Burke JF, Tompkins RG: Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med 20:1508-1512, 1992.
27. Order SE, Moncrief JA: Vascular destruction and revascularization in severe thermal injuries. Surg Forum 15:37-39, 1964.
28. LeVoyer T, Cioffi WG Jr, Pratt L, Shippee R, McManus WF, Mason AD Jr, Pruitt BA Jr: Alterations in intestinal permeability after thermal injury. Arch Surg 127:26-29; discussion 29-30, 1992.
29. Cope O, Moore FD: A study of capillary permeability in experimental burns and burn shock using radioactive dyes in blood and lymph. J Clin Invest 23:241-257, 1944.
30. Ricketts CR: Molecular permeability of the burned area. Proc Soc Exp Biol Med (New York, NY) 121:770-772, 1966.
31. Arturson G: Pathophysiological aspects of the burn syndrome with special reference to liver injury and alterations of capillary permeability. Acta Chir Scand Suppl 274:1-135, 1961.
32. Jahoor F, Desai M, Herndon DN, Wolfe RR: Dynamics of the protein metabolic response to burn injury. Metabolism 37:330-337, 1988.
33. Clowes GH Jr, Randall HT, Cha CJ: Amino acid and energy metabolism in septic and traumatized patients. JPEN 4:195-205, 1980.
34. Sax HC, Talamini MA, Hasselgren PO, Rosenblum L, Ogle CK, Fischer JE: Increased synthesis of secreted hepatic proteins during abdominal sepsis. J Surg Res 44:109-116, 1988.
35. von Allmen D, Hasselgren PO, Fischer JE: Hepatic protein synthesis in a modified septic rat model. J Surg Res 48:476-480, 1990.
36. Waitzberg DL, Correia MI: Nutritional assessment in the hospitalized patient. Curr Opin Clin Nutr Metab Care 6:531-538, 2003.
37. Fuhrman MP: The albumin-nutrition connection: separating myth from fact. Nutrition (Burbank, Los Angeles County, Calif) 18:199-200, 2002.
38. Downs JH, Haffejee A: Nutritional assessment in the critically ill. Curr Opin Clin Nutr Metab Care 1:275-279, 1998.
39. Martini WZ, Chinkes DL, Wolfe RR: The intracellular free amino acid pool represents tracer precursor enrichment for calculation of protein synthesis in cultured fibroblasts and myocytes. J Nutr 134:1546-1550, 2004.