Injection of demineralized bone matrix with bone marrow concentrate improves healing in unicameral bone cyst

Clinical Orthopaedics and Related Research

Volumn 468, Issue 11, 2010, Pages 3047-3055

  Di Bella, Claudia ^a   Dozza, Barbara ^a   Frisoni, Tommaso ^a   Cevolani, Luca ^a   Donati, Davide ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPREDNISOLONE; CORTICOSTEROID;

ADOLESCENT; ADULT; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE CYST; BONE MATRIX; BONE RADIOGRAPHY; CHILD; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; FOLLOW UP; FRACTURE HEALING; HEALING; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SINGLE DRUG DOSE; STEROID THERAPY; TREATMENT FAILURE; TREATMENT RESPONSE; AUTOTRANSPLANTATION; BONE CYSTS; BONE MARROW TRANSPLANTATION; COMPARATIVE STUDY; COMPLICATION; DRUG EFFECTS; FRACTURES, BONE; INTRALESIONAL DRUG ADMINISTRATION; ITALY; PATHOPHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; RADIOGRAPHY; REGISTER; RISK; RISK ASSESSMENT; RISK FACTOR; TIME; TRANSPLANTATION; WOUND HEALING; YOUNG ADULT;

ADOLESCENT; ADRENAL CORTEX HORMONES; BONE CYSTS; BONE MARROW TRANSPLANTATION; BONE MATRIX; CHILD; CHILD, PRESCHOOL; FEMALE; FRACTURES, BONE; HUMANS; INJECTIONS, INTRALESIONAL; ITALY; MALE; METHYLPREDNISOLONE; ODDS RATIO; PROPORTIONAL HAZARDS MODELS; REGISTRIES; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TRANSPLANTATION, AUTOLOGOUS; TREATMENT FAILURE; WOUND HEALING; YOUNG ADULT;

EID: 77957706783     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-010-1430-5     Document Type: Conference Paper

References (43)

1. JI Ahn JS Park 1994 Pathological fractures secondary to unicameral bone cysts Int Orthop. 18 20 22 1:STN:280:DyaK2c3pt1aqug%3D%3D 10.1007/BF00180173 8021063
2. J Brecelj L Suhodolcan 2007 Continuous decompression of unicameral bone cyst with cannulated screws: a comparative study J Pediatr Orthop B. 16 367 372 17762678
3. M Campanacci R Capanna P Picci 1986 Unicameral and aneurysmal bone cysts Clin Orthop Relat Res. 204 25 36 3956013
4. R Capanna A Dal Monte S Gitelis M Campanacci 1982 The natural history of unicameral bone cyst after steroid injection Clin Orthop Relat Res. 166 204 211 7083674
5. CH Chang RP Stanton J Glutting 2002 Unicameral bone cysts treated by injection of bone marrow or methylprednisolone J Bone Joint Surg Br. 84 407 412 1:STN:280:DC%2BD383mt1yqsw%3D%3D 10.1302/0301-620X.84B3.12115 12002502
6. HS Cho JH Oh HS Kim HG Kang SH Lee 2007 Unicameral bone cysts. A comparison of injection of steroid and grafting with autologous bone marrow J Bone Joint Surg Br. 89 222 226 1:STN:280:DC%2BD2s7it1egsQ%3D%3D 10.2106/JBJS.F.00814 17322439 (Pubitemid 46724593)
7. J Cohen 1970 Etiology of simple bone cysts J Bone Joint Surg Am. 52 1493 1497 1:STN:280:DyaE3M%2Fht1CjsA%3D%3D 5472904
8. J Cohen 1977 Unicameral bone cysts: current synthesis of reported cases Orthop Clin North Am. 8 715 736 1:STN:280:DyaE1c%2FjtFyqsQ%3D%3D 335313
9. C Delloye PL Docquier O Cornu P Poilvache M Peters B Woitrin JJ Rombouts P De Nayer 1998 Simple bone cysts treated with aspiration and single bone marrow injection Int Orthop. 22 134 138 1:STN:280:DyaK1czhsFGrsA%3D%3D 10.1007/s002640050225 9651782 (Pubitemid 28284604)
10. JJ Fahey ET O'Brien 1973 Subtotal resection and grafting in selected cases of solitary unicameral bone cyst J Bone Joint Surg Am. 55 59 68 1:STN:280:DyaE3s7ktVGhtw%3D%3D 4570898
11. JM Farber RP Stanton 1990 Treatment options in unicameral bone cysts Orthopedics. 13 25 32 1:STN:280:DyaK3c7jvVGjtg%3D%3D 2300515
12. GJ Garceau CF Gregory 1954 Solitary unicameral bone cysts J Bone Joint Surg Am. 36 267 280 1:STN:280:DyaG2c%2Fnt1SrtQ%3D%3D 13152136
13. A Hashemi-Nejad WG Cole 1997 Incomplete healing of simple bone cysts after steroid injections J Bone Joint Surg Br. 79 727 730 1:STN:280: DyaK2svntVGlsQ%3D%3D 10.1302/0301-620X.79B5.7825 9331023 (Pubitemid 27434486)
14. P Hernigou A Poignard F Beaujean H Rouard 2005 Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells J Bone Joint Surg Am. 87 1430 1437 10.2106/JBJS.D.02215 15995108 (Pubitemid 40917741)
15. Hosmer DW, Lemeshow S, May S. Applied Survival Analysis: Regression Modeling of Time to Event Data. 2nd Ed. New York, NY: Wiley; 2008.
16. AJ Kaelin GD MacEwen 1989 Unicameral bone cysts: natural history and risk of fracture Int Orthop. 13 275 282 1:STN:280:DyaK3c%2FptlGksQ%3D%3D 10.1007/BF00268511 2599704
17. AD Kanellopoulos AF Mavrogenis PJ Papagelopoulos PN Soucacos 2007 Elastic intramedullary nailing and DBM-bone marrow injection for the treatment of simple bone cysts World J Surg Oncol. 5 111 118 10.1186/1477-7819-5-111 17916249 (Pubitemid 350238624)
18. AD Kanellopoulos CK Yiannakopoulos PN Soucacos 2005 Percutaneous reaming of simple bone cysts in children followed by injection of demineralized bone matrix and autologous bone marrow J Pediatr Orthop. 25 671 675 10.1097/01.bpo.0000164874.36770.42 16199953 (Pubitemid 41243599)
19. JT Killian L Wilkinson S White M Brassard 1998 Treatment of unicameral bone cyst with demineralized bone matrix J Pediatr Orthop. 18 621 624 1:STN:280:DyaK1cvhslCqtw%3D%3D 10.1097/00004694-199809000-00013 9746413 (Pubitemid 28446813)
20. S Komiya K Minamitani Y Sasaguri S Hashimoto M Morimatsu A Inoue 1993 Simple bone cyst: treatment by trepanation and studies on bone resorptive factors in cyst fluid with a theory of its pathogenesis Clin Orthop Relat Res. 287 204 211 8448944
21. F Lokiec E Ezra O Khermosh S Weintroub 1996 Simple bone cysts treated by percutaneous autologous bone marrow grafting J Bone Joint Surg Br. 78 934 937 1:STN:280:DyaK2s7gvVKruw%3D%3D 10.1302/0301-620X78B6.6840 8951010
22. JT Makley MJ Joyce 1989 Unicameral bone cyst (simple bone cyst) Orthop Clin North Am. 20 407 415 1:STN:280:DyaL1M3ps1arsQ%3D%3D 2740103
23. DW McKay SS Nason 1977 Treatment of unicameral bone cysts by subtotal resection without grafts J Bone Joint Surg Am. 59 515 519 1:STN:280: DyaE2s7osl2rtw%3D%3D 325011
24. G Mik A Arkader A Manteghi JP Dormans 2009 Results of a minimally invasive technique for treatment of unicameral bone cysts Clin Orthop Relat Res. 467 2949 2954 10.1007/s11999-009-1008-2 19653053
25. T Milbrandt J Hopkins 2007 Unicameral bone cysts: etiology and treatment Curr Opin Orthop. 18 555 560 10.1097/BCO.0b013e3282f05890 (Pubitemid 350293721)
26. CS Neer KC Francis AD Johnston HA Kiernan 1973 Current concepts on the treatment of solitary unicameral bone cyst Clin Orthop Relat Res. 97 40 51 10.1097/00003086-197311000-00008 4590225
27. C Neer KC Francis RC Marcove J Terz P Carbonara 1966 Treatment of unicameral bone cyst. A follow-up study of one hundred seventy-five cases J Bone Joint Surg Am. 48 731 745 15580740
28. A Roposch V Saraph WE Linhart 2000 Flexible intramedullary nailing for the treatment of unicameral bone cysts in long bones J Bone Joint Surg Am. 82 1447 1453 11057473
29. RK Rosenthal J Folkman J Glowacki 1999 Demineralized bone implants for nonunion fractures, bone cysts, and fibrous lesions Clin Orthop Relat Res. 364 61 69 10.1097/00003086-199907000-00009 10416393
30. BT Rougraff TJ Kling 2002 Treatment of active unicameral bone cysts with percutaneous injection of demineralized bone matrix and autogenous bone marrow J Bone Joint Surg Am. 84 921 929 12063325
31. F Santori S Ghera V Castelli 1988 Treatment of solitary bone cysts with intramedullary nailing Orthopedics. 11 873 878 1:STN:280:DyaL1c3mt1Onug%3D%3D 3387334
32. O Scaglietti PG Marchetti P Bartolozzi 1979 The effects of methylprednisolone acetate in the treatment of bone cysts. Results of three years follow-up J Bone Joint Surg Br. 61 200 204 438272
33. O Scaglietti PG Marchetti P Bartolozzi 1982 Final results obtained in the treatment of bone cysts with methylprednisolone acetate (Depo-Medro) and a discussion of results achieved in other bone lesions Clin Orthop Relat Res. 165 33 42 6804147
34. KF Spence Jr RW Bright SP Fitzgerald KW Sell 1976 Solitary unicameral bone cyst: treatment with freeze-dried crushed cortical-bone allograft: a review of one hundred and forty-four cases J Bone Joint Surg Am. 58 636 641 777005
35. AD Sung ME Anderson D Zurakowski FJ Hornicek MC Gebhardt 2008 Unicameral bone cyst. A retrospective study of three surgeries Clin Orthop Relat Res. 466 2519 2526 10.1007/s11999-008-0407-0 18679761
36. D Thawrani CC Thai RD Welch L Copley CE Johnston 2009 Successful treatment of unicameral bone cyst by single percutaneous injection of α-BSM J Pediatr Orthop. 29 511 517 19568026
37. L Trombi L Mattii S Pacini D D'Alessandro B Battolla E Orciuolo G Buda R Fazzi S Galimberti M Petrini 2008 Human autologous plasma-derived clot as a biological scaffold for mesenchymal stem cells in treatment of orthopedic healing J Orthop Res. 26 176 183 10.1002/jor.20490 17868116 (Pubitemid 351220135)
38. DA Vasconcellos SM Yandow AM Grace BM Moritz LD Marley RR Fillman 2007 Cyst Index. A non predictor of simple bone cyst fracture J Pediatr Orthop. 27 307 310 17414015
39. Virchow R. On the formation of bony cysts. In: Uber die Bilding von Knochencysten. Berlin, Germany: SB Akad Wiss; 1876:369-381.
40. R Wilkins 2000 Unicameral bone cysts J Am Acad Orthop Surg. 8 217 224 1:STN:280:DC%2BD3cvhvFSjsw%3D%3D 10951110
41. JG Wright S Yandow S Donaldson L Marley 2008 A randomized clinical trial comparing intralesional bone marrow and steroid injection for simple bone cyst J Bone Joint Surg Am. 90 722 730 10.2106/JBJS.G.00620 18381307 (Pubitemid 351499958)
42. SM Yandow G Lundeen SM Scott C Coffin 1998 Autogenic bone marrow injections as a treatment for simple bone cyst J Pediatr Orthop. 18 616 620 1:STN:280:DyaK1cvhslCqtg%3D%3D 10.1097/00004694-199809000-00012 9746412 (Pubitemid 28446812)
43. MM Zamzam AA Abak KA Bakarma FF Aj-Jassir KI Khoshhal MM Zamzami 2009 Efficacy of aspiration and autogenous bone marrow injection in the treatment of simple bone cysts Int Orthop. 33 1353 1358 10.1007/s00264-008-0619-7 18622614