A randomized clinical trial comparing intralesional bone marrow and steroid injections for simple bone cysts

Journal of Bone and Joint Surgery

Volumn 90, Issue 4, 2008, Pages 722-730

  Wright, James G ^a   Yandow, Suzanne ^b   Donaldson, Sandra ^a   Marley, Lisa ^c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b Central Texas Pediatric Orthopaedics   (United States)

^c SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPREDNISOLONE ACETATE;

ADOLESCENT; ARTICLE; BONE CYST; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; FUNCTIONAL ASSESSMENT; HUMAN; INTERMETHOD COMPARISON; MALE; MULTICENTER STUDY; OPTIMAL DRUG DOSE; PAIN ASSESSMENT; PRIORITY JOURNAL; RADIOLOGIST; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCHOOL CHILD; SCLEROSIS; SINGLE BLIND PROCEDURE; TREATMENT OUTCOME; WOUND HEALING;

EID: 41849129555     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/JBJS.G.00620     Document Type: Article

References (38)

1. Neer CS 2nd, Francis KC, Marcove RC, Terz J, Carbonara PN. Treatment of unicameral bone cyst. A follow-up study of one hundred seventy-five cases. J Bone Joint Surg Am. 1966;48:731-45.
2. Oppenheim WL, Galleno H. Operative treatment versus steroid injection in the management of unicameral bone cysts. J Pediatr Orthop. 1984;4:1-7.
3. Hashemi-Nejad A, Cole WG. Incomplete healing of simple bone cysts after steroid injections. J Bone Joint Surg Br. 1997;79:727-30.
4. Lokiec F, Ezra E, Meller I, Rollender I, Wientroub B. Percutaneous autologous marrow grafting in simple bone cysts - treatment considerations and efficacy. Read at the annual meeting of the Pediatric Orthopaedic Society of North America; 1998; Cleveland, Ohio.
5. Dormans JP, Sankar WN, Moroz L, Erol B. Percutaneous intramedullary decompression, curettage, and grafting with medical-grade calcium sulfate pellets for unicameral bone cysts in children: a new minimally invasive technique. J Pediatr Orthop. 2005;25:804-11.
6. Killian JT, Wilkinson L, White S, Brassard M. Treatment of unicameral bone cyst with demineralized bone matrix. J Pediatr Orthop. 1998;18:621-4.
7. Campanacci M, Capanna R, Picci P. Unicameral and aneurysmal bone cysts. Clin Orthop Relat Res. 1986;204:25-36.
8. Scaglietti O, Marchetti PG, Bartolozzi P. The effects of methylprednisoione acetate in the treatment of bone cysts. Results of three years follow-up. J Bone Joint Surg Br. 1979;61:200-4.
9. Lokiec F, Ezra E, Khermosh O, Weintroub S. Simple bone cysts treated by percutaneous autologous marrow grafting. J Bone Joint Surg Br. 1996;78:934-7.
10. Yandow SM, Lundeen G, Scott SM, Coffin C. Autogenic bone marrow injections as a treatment for simple bone cyst. J Pediatr Orthop. 1998;18:616-20.
11. Delloye C, Docquier PL, Cornu O, Poilvache P, Peters M, Woitrin B, Rombouts JJ, De Nayer P. Simple bone cysts treated with aspiration and a single bone marrow injection. Int Op. 1998;22:134-8.
12. Young NL, Wright JG. Measuring pediatric physical function. J Pediatr Orthop. 1995;15:244-53.
13. Young NL, Yoshida KK, Williams JI, Bombardier C, Wright JG. The role of children in reporting their physical disability. Arch Phys Med Rehabil. 1995;76:913-8.
14. Young NL, Yoshida KK, Williams JI, Bombardier C, Wright JG. The context of measuring disability: does it matter whether capability or performance is measured? J Clin Epidemiol. 1996;49:1097-101.
15. Young NL, Williams JI, Yoshida KK, Wright JG. Measurement properties of the activities scale for kids. J Clin Epidemiol. 2000;53:125-37.
16. Beyer JE, Denyes MJ, Villarruel AM. The creation, validation, and continuing development of the Oucher: a measure of pain intensity in children. J Pediatr Nurs. 1992;7:335-46.
17. Hester NK. The preoperational child's reaction to immunizations. Nurs Res. 1979;28:250-4.
18. Hester N, Foster R, Kristensen K. Measurement of pain in children: generalizability and validity of the pain ladder and the Poker Chip Tool. In: Tyler D, Krane E, editors. Pediatric Pain. New York: Raven; 1990. p 79-84.
19. Huskisson E. Visual analogue scales. In: Melzack R, editor. Pain measurement and assessment. New York: Raven; 1983. p 33-7.
20. Melamed BG, Siegel U. Reduction of anxiety in children facing hospitalization and surgery by use of filmed modeling. J Consult Clin Psychol. 1975;43:511-21.
21. Beyer J, Aradine C. The convergent and discriminant validity of a self-report measure of pain intensity for children. Child Health Care. 1988;16:274-82.
22. Chigira M, Maehara S, Arita S, Udagawa E. The aetiology and treatment of simple bone cysts. J Bone Joint Surg Br. 1983;65:633-7.
23. Capanna R, Dal Monte A, Gitelis S, Campanacci M. The natural history of unicameral bone cyst after steroid injection. Clin Orthop Relat Res. 1982;166:204-11.
24. Scaglietti O, Marchetti PG, Bartolozzi P. Final results obtained in the treatment of bone cysts with methylprednisoione acetate (depo-medrol) and a discussion of results achieved in other bone lesions. Clin Orthop Relat Res. 1982,165:33-42.
25. Healey JH, Zimmerman PA, McDonnell JM, Lane JH. Percutaneous bone marrow grafting of delayed union and nonunion in cancer patients. Clin Orthop Relat Res. 1990;256:280-5.
26. Connolly J, Guse R, Lippiello L, Dehne R. Development of an osteogenic bone-marrow preparation. J Bone Joint Surg Am. 1989;71:684-91.
27. Stinchfield FE, Sankaran B, Samilson R. The effect of anticoagulant therapy on bone repair. J Bone Joint Surg Am. 1956;38:270-82.
28. Batinic D, Marusic D, Pavletic Z, Bogdanic V, Uzarevic B, Nemet D, Labar B. Relationship between differing volumes of bone marrow aspirates and their cellular composition. Bone Marrow Transplant. 1990;6:103-7.
29. Muschler GF, Boehm C, Easley K. Aspiration to obtain osteoblast progenitor cells from human bone marrow: the influence of aspiration volume. J Bone Joint Surg Am. 1997;79:1699-709. Erratum in: J Bone Joint Surg Am. 1998;80:302.
30. Köse N, Gökturk E, Turgut Akin, Günal I, Seber S. Percutaneous autologous bone marrow grafting for simple bone cysts. Bull Hosp Jt Dis. 1999;58:105-10.
31. Csizy M, Buckley RE, Fennell C. Benign calcaneal bone cyst and pathologic fracture - surgical treatment with injectable calcium-phosphate bone cement (Norian): a case report. Foot Anke Int. 2001;22:507-10.
32. Tsuchiya H, Abdel-Wanis ME, Uehara K, Tomita K, Takagi Y, Yasutake H. Cannulation of simple bone cysts. J Bone Joint Surg Br. 2002;84:245-8.
33. Roposch A, Saraph V, Linhart WE. Flexible intramedullary nailing for the treatment of unicameral bone cysts in long bones. J Bone Joint Surg Am. 2000;82:1447-53.
34. Chang CH, Stanton RP, Glutting J. Unicameral bone cysts treated by injection of bone marrow or methylprednisolone. J Bone Joint Surg Br. 2002;84:407-12.
35. Docquier PL, Delloye C. Autologous bone marrow injection in the management of simple bone cysts in children. Acta Ortho Belg. 2004;70:204-13.
36. Schulz KF, Altman DG, Moher D. Allocation concealment in clinical trials. JAMA. 2002;288:2406-9.
37. Snyder BD, Hauser-Kara DA, Hipp JA, Zurakowski D, Hecht AC, Gebhardt MC. Predicting fracture through benign skeletal lesions with quantitative computed tomography. J Bone Joint Surg Am. 2006;88:55-70.
38. Hernigou P, Poignard A, Beaujean F, Rouard H. Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells. J Bone Joint Surg Am. 2005;87:1430-7.