-
1
-
-
0028330299
-
The pharmacology of the integrins
-
Cox, D., Aoki, T., Seki, J., Motoyama, Y., and Yoshida, K. (1994) The pharmacology of the integrins Med Res Rev 14, 195-228.
-
(1994)
Med Res Rev
, vol.14
, pp. 195-228
-
-
Cox, D.1
Aoki, T.2
Seki, J.3
Motoyama, Y.4
Yoshida, K.5
-
2
-
-
63849307598
-
Integrins and proximal signaling mechanisms in cardiovascular disease
-
Lal, H., Verma, S.K., Foster, D.M., Golden, H.B., Reneau, J.C., Watson, L.E., Singh, H., and Dostal, D.E. (2009) Integrins and proximal signaling mechanisms in cardiovascular disease Front Biosci 14, 2307-34.
-
(2009)
Front Biosci
, vol.14
, pp. 2307-34
-
-
Lal, H.1
Verma, S.K.2
Foster, D.M.3
Golden, H.B.4
Reneau, J.C.5
Watson, L.E.6
Singh, H.7
Dostal, D.E.8
-
3
-
-
0025033952
-
Pharmacodynamic study of F(ab')2 fragments of murine monoclonal antibody 7E3 directed against human platelet glycoprotein IIb/IIIa in patients with unstable angina pectoris
-
Gold, H.K., Gimple, L.W., Yasuda, T., Leinbach, R.C., Werner, W., Holt, R., Jordan, R., Berger, H., Collen, D., and Coller, B.S. (1990) Pharmacodynamic study of F(ab')2 fragments of murine monoclonal antibody 7E3 directed against human platelet glycoprotein IIb/IIIa in patients with unstable angina pectoris J Clin Invest 86, 651-9.
-
(1990)
J Clin Invest
, vol.86
, pp. 651-9
-
-
Gold, H.K.1
Gimple, L.W.2
Yasuda, T.3
Leinbach, R.C.4
Werner, W.5
Holt, R.6
Jordan, R.7
Berger, H.8
Collen, D.9
Coller, B.S.10
-
4
-
-
0001427937
-
Novel antiplatelet therapies: Recent advances in the development of platelet GPIIb/IIIa receptor antagonists
-
In: Serruys P.W. and Holmes D., eds., 3rd edition. Philadelphia, PA: Current Medicine;
-
Mousa, S., and Topol, E. Novel antiplatelet therapies: Recent advances in the development of platelet GPIIb/IIIa receptor antagonists. In: Serruys, P.W., and Holmes, D., eds. Current Review of Interventional Cardiology, 3rd edition. Philadelphia, PA: Current Medicine;1997:114-29.
-
(1997)
Current Review of Interventional Cardiology
, pp. 114-29
-
-
Mousa, S.1
Topol, E.2
-
5
-
-
0027957884
-
Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist
-
Mousa, S.A., Bozarth, J.M., Forsythe, M.S., Jackson, S.M., Leamy, A., Diemer, M.M., Kapil, R.P., Knabb, R.M., Mayo, M.C., Pierce, S.K., et al. (1994) Antiplatelet and antithrombotic efficacy of DMP 728, a novel platelet GPIIb/IIIa receptor antagonist Circulation 89, 3-12.
-
(1994)
Circulation
, vol.89
, pp. 3-12
-
-
Mousa, S.A.1
Bozarth, J.M.2
Forsythe, M.S.3
Jackson, S.M.4
Leamy, A.5
Diemer, M.M.6
Kapil, R.P.7
Knabb, R.M.8
Mayo, M.C.9
Pierce, S.K.10
-
6
-
-
0027749470
-
Antiplatelet efficacy and specificity of DMP728, a novel platelet GPIIb/IIIa receptor antagonist
-
Mousa, S.A., Bozarth, J.M., Forsythe, M.S., Lorelli, W., Thoolen, M.J., Ramachandran, N., Jackson, S., De Grado, W., and Reilly, T.M. (1993) Antiplatelet efficacy and specificity of DMP728, a novel platelet GPIIb/IIIa receptor antagonist Cardiology 83, 374-82.
-
(1993)
Cardiology
, vol.83
, pp. 374-82
-
-
Mousa, S.A.1
Bozarth, J.M.2
Forsythe, M.S.3
Lorelli, W.4
Thoolen, M.J.5
Ramachandran, N.6
Jackson, S.7
De Grado, W.8
Reilly, T.M.9
-
7
-
-
59749099401
-
Defining the role of platelet glycoprotein receptor inhibitors in STEMI: Focus on tirofiban
-
van't Hof, A.W., and Valgimigli, M. (2009) Defining the role of platelet glycoprotein receptor inhibitors in STEMI: Focus on tirofiban Drugs 69, 85-100.
-
(2009)
Drugs
, vol.69
, pp. 85-100
-
-
Van't Hof, A.W.1
Valgimigli, M.2
-
8
-
-
0028362876
-
Requirement of vascular integrin alpha v beta 3 for angiogenesis
-
Brooks, P.C., Clark, R.A., and Cheresh, D.A. (1994) Requirement of vascular integrin alpha v beta 3 for angiogenesis Science 264, 569-71.
-
(1994)
Science
, vol.264
, pp. 569-71
-
-
Brooks, P.C.1
Clark, R.A.2
Cheresh, D.A.3
-
9
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks, P.C.,Montgomery, A.M., Rosenfeld, M., Reisfeld, R.A., Hu, T., Klier, G., and Cheresh, D.A. (1994) Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels Cell 79, 1157-64.
-
(1994)
Cell
, vol.79
, pp. 1157-64
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
Reisfeld, R.A.4
Hu, T.5
Klier, G.6
Cheresh, D.A.7
-
10
-
-
0025666651
-
Carbohydrate ligands of the LEC cell adhesion molecules
-
Brandley, B.K., Swiedler, S.J., and Robbins, P.W. (1990) Carbohydrate ligands of the LEC cell adhesion molecules Cell 63, 861-3.
-
(1990)
Cell
, vol.63
, pp. 861-3
-
-
Brandley, B.K.1
Swiedler, S.J.2
Robbins, P.W.3
-
11
-
-
0026776328
-
An endothelial ligand for L-selectin is a novel mucin-like molecule
-
Lasky, L.A., Singer, M.S., Dowbenko, D., Imai, Y., Henzel, W.J., Grimley, C., Fennie, C., Gillett, N.,Watson, S.R., and Rosen, S.D. (1992) An endothelial ligand for L-selectin is a novel mucin-like molecule Cell 69, 927-38.
-
(1992)
Cell
, vol.69
, pp. 927-38
-
-
Lasky, L.A.1
Singer, M.S.2
Dowbenko, D.3
Imai, Y.4
Henzel, W.J.5
Grimley, C.6
Fennie, C.7
Gillett, N.8
Watson, S.R.9
Rosen, S.D.10
-
12
-
-
0026445723
-
Selectins: Interpreters of cell-specific carbohydrate information during inflammation
-
Lasky, L.A. (1992) Selectins: Interpreters of cell-specific carbohydrate information during inflammation Science 258, 964-9.
-
(1992)
Science
, vol.258
, pp. 964-9
-
-
Lasky, L.A.1
-
13
-
-
0025572709
-
ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex
-
Phillips, M.L., Nudelman, E., Gaeta, F.C., Perez, M., Singhal, A.K., Hakomori, S., and Paulson, J.C. (1990) ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex Science 250, 1130-2.
-
(1990)
Science
, vol.250
, pp. 1130-2
-
-
Phillips, M.L.1
Nudelman, E.2
Gaeta, F.C.3
Perez, M.4
Singhal, A.K.5
Hakomori, S.6
Paulson, J.C.7
-
14
-
-
0027171780
-
Protective effects of oligosaccharides in P-selectin-dependent lung injury
-
Mulligan, M.S., Paulson, J.C., De Frees, S., Zheng, Z.L., Lowe, J.B., and Ward, P.A. (1993) Protective effects of oligosaccharides in P-selectin-dependent lung injury Nature 364, 149-51.
-
(1993)
Nature
, vol.364
, pp. 149-51
-
-
Mulligan, M.S.1
Paulson, J.C.2
De Frees, S.3
Zheng, Z.L.4
Lowe, J.B.5
Ward, P.A.6
-
15
-
-
0027164220
-
In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury
-
Weyrich, A.S., Ma, X.Y., Lefer, D.J., Albertine, K.H., and Lefer, A.M. (1993) In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury J Clin Invest 91, 2620-9.
-
(1993)
J Clin Invest
, vol.91
, pp. 2620-9
-
-
Weyrich, A.S.1
Ma, X.Y.2
Lefer, D.J.3
Albertine, K.H.4
Lefer, A.M.5
-
16
-
-
0342888818
-
The effect of P-selectin blockade on neointimal lesion development in a primate carotid injury model
-
Hullinger, T., DeGraaf, G., Hartman, J., and Shebuski, R. (1995) The effect of P-selectin blockade on neointimal lesion development in a primate carotid injury model FASEB 9.
-
(1995)
FASEB
, vol.9
-
-
Hullinger, T.1
DeGraaf, G.2
Hartman, J.3
Shebuski, R.4
-
17
-
-
35548974811
-
Paradigms for glycan-binding receptors in cell adhesion
-
Taylor, M.E., and Drickamer, K. (2007) Paradigms for glycan-binding receptors in cell adhesion Curr Opin Cell Biol 19, 572-7.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 572-7
-
-
Taylor, M.E.1
Drickamer, K.2
-
18
-
-
0028345255
-
Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. The EPIC investigators
-
Topol, E.J., Califf, R.M., Weisman, H.F., Ellis, S.G., Tcheng, J.E., Worley, S., Ivanhoe, R., George, B.S., Fintel, D., Weston, M., et al. (1994) Randomised trial of coronary intervention with antibody against platelet IIb/IIIa integrin for reduction of clinical restenosis: Results at six months. The EPIC investigators Lancet 343, 881-6.
-
(1994)
Lancet
, vol.343
, pp. 881-6
-
-
Topol, E.J.1
Califf, R.M.2
Weisman, H.F.3
Ellis, S.G.4
Tcheng, J.E.5
Worley, S.6
Ivanhoe, R.7
George, B.S.8
Fintel, D.9
Weston, M.10
-
19
-
-
0027237424
-
Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1
-
Berlin, C., Berg, E.L., Briskin, M.J., Andrew, D.P., Kilshaw, P.J., Holzmann, B., Weissman, I.L., Hamann, A., and Butcher, E.C. (1993) Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1 Cell 74, 185-95.
-
(1993)
Cell
, vol.74
, pp. 185-95
-
-
Berlin, C.1
Berg, E.L.2
Briskin, M.J.3
Andrew, D.P.4
Kilshaw, P.J.5
Holzmann, B.6
Weissman, I.L.7
Hamann, A.8
Butcher, E.C.9
-
20
-
-
0025161990
-
VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
-
Elices, M.J., Osborn, L., Takada, Y., Crouse, C., Luhowskyj, S., Hemler, M.E., and Lobb, R.R. (1990) VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site Cell 60, 577-84.
-
(1990)
Cell
, vol.60
, pp. 577-84
-
-
Elices, M.J.1
Osborn, L.2
Takada, Y.3
Crouse, C.4
Luhowskyj, S.5
Hemler, M.E.6
Lobb, R.R.7
-
21
-
-
0026343689
-
Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo
-
Issekutz, T.B. (1991) Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo J Immunol 147, 4178-84.
-
(1991)
J Immunol
, vol.147
, pp. 4178-84
-
-
Issekutz, T.B.1
-
22
-
-
0028181865
-
Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo
-
Hamann, A., Andrew, D.P., Jablonski- Westrich, D., Holzmann, B., and Butcher, E.C. (1994) Role of alpha 4-integrins in lymphocyte homing to mucosal tissues in vivo J Immunol 152, 3282-93.
-
(1994)
J Immunol
, vol.152
, pp. 3282-93
-
-
Hamann, A.1
Andrew, D.P.2
Jablonski-Westrich, D.3
Holzmann, B.4
Butcher, E.C.5
-
23
-
-
0027982876
-
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
-
Springer, T.A. (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm Cell 76, 301-14.
-
(1994)
Cell
, vol.76
, pp. 301-14
-
-
Springer, T.A.1
-
24
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
Yednock, T.A., Cannon, C., Fritz, L.C., Sanchez-Madrid, F., Steinman, L., and Karin, N. (1992) Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin Nature 356, 63-6.
-
(1992)
Nature
, vol.356
, pp. 63-6
-
-
Yednock, T.A.1
Cannon, C.2
Fritz, L.C.3
Sanchez-Madrid, F.4
Steinman, L.5
Karin, N.6
-
25
-
-
0028941871
-
The adhesion molecule and cytokine profile of multiple sclerosis lesions
-
Cannella, B., and Raine, C.S. (1995) The adhesion molecule and cytokine profile of multiple sclerosis lesions Ann Neurol 37, 424-35.
-
(1995)
Ann Neurol
, vol.37
, pp. 424-35
-
-
Cannella, B.1
Raine, C.S.2
-
26
-
-
0023205115
-
A monoclonal antibody (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes
-
Cerf-Bensussan, N., Jarry, A., Brousse, N., Lisowska-Grospierre, B., Guy-Grand, D., and Griscelli, C. (1987) A monoclonal antibody (HML-1) defining a novel membrane molecule present on human intestinal lymphocytes Eur J Immunol 17, 1279-85.
-
(1987)
Eur J Immunol
, vol.17
, pp. 1279-85
-
-
Cerf-Bensussan, N.1
Jarry, A.2
Brousse, N.3
Lisowska-Grospierre, B.4
Guy-Grand, D.5
Griscelli, C.6
-
27
-
-
0033843942
-
Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin
-
Kim, S., Bell, K., Mousa, S.A., and Varner, J.A. (2000) Regulation of angiogenesis in vivo by ligation of integrin alpha5beta1 with the central cell-binding domain of fibronectin Am J Pathol 156, 1345-62.
-
(2000)
Am J Pathol
, vol.156
, pp. 1345-62
-
-
Kim, S.1
Bell, K.2
Mousa, S.A.3
Varner, J.A.4
-
28
-
-
0034646204
-
A nonpeptide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin alpha 5beta 1-fibronectin-M1 protein complexes
-
Cue, D., Southern, S.O., Southern, P.J., Prabhakar, J., Lorelli, W., Smallheer, J.M., Mousa, S.A., and Cleary, P.P. (2000) A nonpeptide integrin antagonist can inhibit epithelial cell ingestion of Streptococcus pyogenes by blocking formation of integrin alpha 5beta 1-fibronectin-M1 protein complexes Proc Natl Acad Sci USA 97, 2858-63.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2858-63
-
-
Cue, D.1
Southern, S.O.2
Southern, P.J.3
Prabhakar, J.4
Lorelli, W.5
Smallheer, J.M.6
Mousa, S.A.7
Cleary, P.P.8
-
29
-
-
2242477091
-
Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty
-
The EPIC Investigators
-
The EPIC Investigators (1994) Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty N Engl J Med 330, 956-61.
-
(1994)
N Engl J Med
, vol.330
, pp. 956-61
-
-
-
30
-
-
0027194452
-
Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study
-
Kleiman, N.S., Ohman, E.M., Califf, R.M., George, B.S., Kereiakes, D., Aguirre, F.V., Weisman, H., Schaible, T., and Topol, E.J. (1993) Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study J Am Coll Cardiol 22, 381-9.
-
(1993)
J Am Coll Cardiol
, vol.22
, pp. 381-9
-
-
Kleiman, N.S.1
Ohman, E.M.2
Califf, R.M.3
George, B.S.4
Kereiakes, D.5
Aguirre, F.V.6
Weisman, H.7
Schaible, T.8
Topol, E.J.9
-
31
-
-
0028117857
-
Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in highrisk coronary angioplasty
-
Tcheng, J.E., Ellis, S.G., George, B.S., Kereiakes, D.J., Kleiman, N.S., Talley, J.D., Wang, A.L., Weisman, H.F., Califf, R.M., and Topol, E.J. (1994) Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in highrisk coronary angioplasty Circulation 90, 1757-64.
-
(1994)
Circulation
, vol.90
, pp. 1757-64
-
-
Tcheng, J.E.1
Ellis, S.G.2
George, B.S.3
Kereiakes, D.J.4
Kleiman, N.S.5
Talley, J.D.6
Wang, A.L.7
Weisman, H.F.8
Califf, R.M.9
Topol, E.J.10
-
32
-
-
0028930680
-
Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT investigators
-
Tcheng, J.E., Harrington, R.A., Kottke- Marchant, K., Kleiman, N.S., Ellis, S.G., Kereiakes, D.J., Mick, M.J., Navetta, F.I., Smith, J.E., Worley, S.J., et al. (1995) Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT investigators Circulation 91, 2151-7.
-
(1995)
Circulation
, vol.91
, pp. 2151-7
-
-
Tcheng, J.E.1
Harrington, R.A.2
Kottke- Marchant, K.3
Kleiman, N.S.4
Ellis, S.G.5
Kereiakes, D.J.6
Mick, M.J.7
Navetta, F.I.8
Smith, J.E.9
Worley, S.J.10
-
33
-
-
0027379391
-
MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man
-
Peerlinck, K., De Lepeleire, I., Goldberg,M., Farrell, D., Barrett, J., Hand, E., Panebianco, D., Deckmyn, H., Vermylen, J., and Arnout, J. (1993) MK-383 (L-700,462), a selective nonpeptide platelet glycoprotein IIb/IIIa antagonist, is active in man Circulation 88, 1512-7.
-
(1993)
Circulation
, vol.88
, pp. 1512-7
-
-
Peerlinck, K.1
De Lepeleire, I.2
Goldberg, M.3
Farrell, D.4
Barrett, J.5
Hand, E.6
Panebianco, D.7
Deckmyn, H.8
Vermylen, J.9
Arnout, J.10
-
34
-
-
0032477680
-
Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial. Thrombolysis in myocardial infarction
-
Cannon, C.P., McCabe, C.H., Borzak, S., Henry, T.D., Tischler, M.D., Mueller, H.S., Feldman, R., Palmeri, S.T., Ault, K., Hamilton, S.A., Rothman, J.M., Novotny, W.F., and Braunwald, E. (1998) Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial. Thrombolysis in myocardial infarction Circulation 97, 340-9.
-
(1998)
Circulation
, vol.97
, pp. 340-9
-
-
Cannon, C.P.1
McCabe, C.H.2
Borzak, S.3
Henry, T.D.4
Tischler, M.D.5
Mueller, H.S.6
Feldman, R.7
Palmeri, S.T.8
Ault, K.9
Hamilton, S.A.10
Rothman, J.M.11
Novotny, W.F.12
Braunwald, E.13
-
35
-
-
0342872079
-
Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, lefradafiban, in men
-
Muller, T.H., Weisenberger, H., Brickl, R., Narjes, H., Himmelsbach, F., and Krause, J. (1997) Profound and sustained inhibition of platelet aggregation by fradafiban, a nonpeptide platelet glycoprotein IIb/IIIa antagonist, and its orally active prodrug, lefradafiban, in men Circulation 96, 1130-8.
-
(1997)
Circulation
, vol.96
, pp. 1130-8
-
-
Muller, T.H.1
Weisenberger, H.2
Brickl, R.3
Narjes, H.4
Himmelsbach, F.5
Krause, J.6
-
36
-
-
0030754004
-
First chronic platelet glycoprotein IIb/IIIa integrin blockade. A randomized, placebocontrolled pilot study of xemilofiban in unstable angina with percutaneous coronary interventions
-
Simpfendorfer, C., Kottke-Marchant, K., Lowrie, M., Anders, R.J., Burns, D.M., Miller, D.P., Cove, C.S., DeFranco, A.C., Ellis, S.G., Moliterno, D.J., Raymond, R.E., Sutton, J.M., and Topol, E.J. (1997) First chronic platelet glycoprotein IIb/IIIa integrin blockade. A randomized, placebocontrolled pilot study of xemilofiban in unstable angina with percutaneous coronary interventions Circulation 96, 76-81.
-
(1997)
Circulation
, vol.96
, pp. 76-81
-
-
Simpfendorfer, C.1
Kottke-Marchant, K.2
Lowrie, M.3
Anders, R.J.4
Burns, D.M.5
Miller, D.P.6
Cove, C.S.7
DeFranco, A.C.8
Ellis, S.G.9
Moliterno, D.J.10
Raymond, R.E.11
Sutton, J.M.12
Topol, E.J.13
-
37
-
-
0033870256
-
Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease
-
Harrington, R.A., Armstrong, P.W., Graffagnino, C., Van De Werf, F., Kereiakes, D.J., Sigmon, K.N., Card, T., Joseph, D.M., Samuels, R., Granett, J., Chan, R., Califf, R.M., and Topol, E.J. (2000) Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease Circulation 102, 728-35.
-
(2000)
Circulation
, vol.102
, pp. 728-35
-
-
Harrington, R.A.1
Armstrong, P.W.2
Graffagnino, C.3
Van De Werf, F.4
Kereiakes, D.J.5
Sigmon, K.N.6
Card, T.7
Joseph, D.M.8
Samuels, R.9
Granett, J.10
Chan, R.11
Califf, R.M.12
Topol, E.J.13
-
38
-
-
0031856736
-
Orally active Isoxazoline GOIIb/IIIa antagonists
-
Mousa, S., and Wityak, J. (1998) Orally active Isoxazoline GOIIb/IIIa antagonists Cardiovas Drug Rev 16, 48-61.
-
(1998)
Cardiovas Drug Rev
, vol.16
, pp. 48-61
-
-
Mousa, S.1
Wityak, J.2
-
39
-
-
0031808875
-
Long-term administration of glycoprotein IIb/IIIa antagonists
-
Quinn, M., and Fitzgerald, D.J. (1998) Long-term administration of glycoprotein IIb/IIIa antagonists Am Heart J 135, S113-8.
-
(1998)
Am Heart J
, vol.135
-
-
Quinn, M.1
Fitzgerald, D.J.2
-
40
-
-
0032477682
-
Oral platelet glycoprotein IIb/IIIa receptor antagonists: The present challenge is safety
-
Vorchheimer, D.A., and Fuster, V. (1998) Oral platelet glycoprotein IIb/IIIa receptor antagonists: The present challenge is safety Circulation 97, 312-4.
-
(1998)
Circulation
, vol.97
, pp. 312-4
-
-
Vorchheimer, D.A.1
Fuster, V.2
-
41
-
-
0031808479
-
Novel technetium-99m-labeled platelet GPIIb/IIIa receptor antagonists as potential imaging agents for venous and arterial thrombosis
-
Mousa, S.A., Bozarth, J.M., Edwards, S., Carroll, T., and Barrett, J. (1998) Novel technetium-99m-labeled platelet GPIIb/IIIa receptor antagonists as potential imaging agents for venous and arterial thrombosis Coron Artery Dis 9, 131-41.
-
(1998)
Coron Artery Dis
, vol.9
, pp. 131-41
-
-
Mousa, S.A.1
Bozarth, J.M.2
Edwards, S.3
Carroll, T.4
Barrett, J.5
-
42
-
-
0031456703
-
Selective alpha v beta 3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha v beta 3 and osteopontin expression during neointima formation
-
Srivatsa, S.S., Fitzpatrick, L.A., Tsao, P.W., Reilly, T.M., Holmes, D.R., Jr., Schwartz, R.S., and Mousa, S.A. (1997) Selective alpha v beta 3 integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha v beta 3 and osteopontin expression during neointima formation Cardiovasc Res 36, 408-28.
-
(1997)
Cardiovasc Res
, vol.36
, pp. 408-28
-
-
Srivatsa, S.S.1
Fitzpatrick, L.A.2
Tsao, P.W.3
Reilly, T.M.4
Holmes Jr., D.R.5
Schwartz, R.S.6
Mousa, S.A.7
-
43
-
-
0028855585
-
The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro
-
Liaw, L., Skinner, M.P., Raines, E.W., Ross, R., Cheresh, D.A., Schwartz, S.M., and Giachelli, C.M. (1995) The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. Role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro J Clin Invest 95, 713-24.
-
(1995)
J Clin Invest
, vol.95
, pp. 713-24
-
-
Liaw, L.1
Skinner, M.P.2
Raines, E.W.3
Ross, R.4
Cheresh, D.A.5
Schwartz, S.M.6
Giachelli, C.M.7
-
44
-
-
0028050538
-
Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin
-
Yue, T.L., McKenna, P.J., Ohlstein, E.H., Farach-Carson, M.C., Butler, W.T., Johanson, K., McDevitt, P., Feuerstein, G.Z., and Stadel, J.M. (1994) Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin Exp Cell Res 214, 459-64.
-
(1994)
Exp Cell Res
, vol.214
, pp. 459-64
-
-
Yue, T.L.1
McKenna, P.J.2
Ohlstein, E.H.3
Farach-Carson, M.C.4
Butler, W.T.5
Johanson, K.6
McDevitt, P.7
Feuerstein, G.Z.8
Stadel, J.M.9
-
45
-
-
0032436238
-
Reduced intimal thickening following alpha(v)beta3 blockade is associated with smooth muscle cell apoptosis
-
van der Zee, R., Murohara, T., Passeri, J., Kearney, M., Cheresh, D.A., and Isner, J.M. (1998) Reduced intimal thickening following alpha(v)beta3 blockade is associated with smooth muscle cell apoptosis Cell Adhes Commun 6, 371-9.
-
(1998)
Cell Adhes Commun
, vol.6
, pp. 371-9
-
-
Van Der Zee, R.1
Murohara, T.2
Passeri, J.3
Kearney, M.4
Cheresh, D.A.5
Isner, J.M.6
-
46
-
-
0036904072
-
The alpha v integrin antagonists as novel anticancer agents: An update
-
Kerr, J.S., Slee, A.M., and Mousa, S.A. (2002) The alpha v integrin antagonists as novel anticancer agents: An update Expert Opin Investig Drugs 11, 1765-74.
-
(2002)
Expert Opin Investig Drugs
, vol.11
, pp. 1765-74
-
-
Kerr, J.S.1
Slee, A.M.2
Mousa, S.A.3
-
47
-
-
34648843428
-
Cyclic RGD peptideconjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins
-
Oba, M., Fukushima, S., Kanayama, N., Aoyagi, K., Nishiyama, N., Koyama, H., and Kataoka, K. (2007) Cyclic RGD peptideconjugated polyplex micelles as a targetable gene delivery system directed to cells possessing alphavbeta3 and alphavbeta5 integrins Bioconjug Chem 18, 1415-23.
-
(2007)
Bioconjug Chem
, vol.18
, pp. 1415-23
-
-
Oba, M.1
Fukushima, S.2
Kanayama, N.3
Aoyagi, K.4
Nishiyama, N.5
Koyama, H.6
Kataoka, K.7
-
48
-
-
0026071846
-
Monoclonal antibodies against intercellular adhesion molecule 1 prolong cardiac allograft survival in cynomolgus monkeys
-
Flavin, T., Ivens, K., Rothlein, R., Faanes, R., Clayberger, C., Billingham, M., and Starnes, V.A. (1991) Monoclonal antibodies against intercellular adhesion molecule 1 prolong cardiac allograft survival in cynomolgus monkeys Transplant Proc 23, 533-4.
-
(1991)
Transplant Proc
, vol.23
, pp. 533-4
-
-
Flavin, T.1
Ivens, K.2
Rothlein, R.3
Faanes, R.4
Clayberger, C.5
Billingham, M.6
Starnes, V.A.7
-
49
-
-
0027413809
-
A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients
-
Discussion 72-3
-
Haug, C.E., Colvin, R.B., Delmonico, F.L., Auchincloss, H., Jr., Tolkoff-Rubin, N., Preffer, F.I., Rothlein, R., Norris, S., Scharschmidt, L., and Cosimi, A.B. (1993) A phase I trial of immunosuppression with anti-ICAM-1 (CD54) mAb in renal allograft recipients Transplantation 55, 766-72; Discussion 72-3.
-
(1993)
Transplantation
, vol.55
, pp. 766-72
-
-
Haug, C.E.1
Colvin, R.B.2
Delmonico, F.L.3
Auchincloss Jr., H.4
Tolkoff-Rubin, N.5
Preffer, F.I.6
Rothlein, R.7
Norris, S.8
Scharschmidt, L.9
Cosimi, A.B.10
-
50
-
-
0029911784
-
Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/aggregation over injured but not denuded endothelium in vivo and ex vivo
-
Rosenblum, W.I., Nelson, G.H., Wormley, B., Werner, P., Wang, J., and Shih, C.C. (1996) Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/aggregation over injured but not denuded endothelium in vivo and ex vivo Stroke 27, 709-11.
-
(1996)
Stroke
, vol.27
, pp. 709-11
-
-
Rosenblum, W.I.1
Nelson, G.H.2
Wormley, B.3
Werner, P.4
Wang, J.5
Shih, C.C.6
-
51
-
-
0032753372
-
Migration of leukocytes across endothelium and beyond: Molecules involved in the transmigration and fate of monocytes
-
Muller, W.A., and Randolph, G.J. (1999) Migration of leukocytes across endothelium and beyond: Molecules involved in the transmigration and fate of monocytes J Leukoc Biol 66, 698-704.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 698-704
-
-
Muller, W.A.1
Randolph, G.J.2
-
52
-
-
0027486922
-
Circulating adhesion molecules in disease
-
Gearing, A.J., and Newman, W. (1993) Circulating adhesion molecules in disease Immunol Today 14, 506-12.
-
(1993)
Immunol Today
, vol.14
, pp. 506-12
-
-
Gearing, A.J.1
Newman, W.2
-
53
-
-
0027294656
-
Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock
-
Newman, W., Beall, L.D., Carson, C.W., Hunder, G.G., Graben, N., Randhawa, Z.I., Gopal, T.V., Wiener-Kronish, J., and Matthay, M.A. (1993) Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock J Immunol 150, 644-54.
-
(1993)
J Immunol
, vol.150
, pp. 644-54
-
-
Newman, W.1
Beall, L.D.2
Carson, C.W.3
Hunder, G.G.4
Graben, N.5
Randhawa, Z.I.6
Gopal, T.V.7
Wiener-Kronish, J.8
Matthay, M.A.9
|