The effect of platelet-rich plasma in vitro on primary cells: Rat osteoblast-like cells and human endothelial cells

Tissue Engineering - Part A

Volumn 16, Issue 10, 2010, Pages 3159-3172

  Mooren, Robert E C M ^a   Hendriks, Eef J ^a   Van Den Beucken, Jeroen J J P ^a   Merkx, Mathijs A W ^a   Meijer, Gert J ^a   Jansen, John A ^a   Stoelinga, Paul J W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BLOOD; CELL PROLIFERATION; ENDOTHELIAL CELLS; PEPTIDES; PLATELETS; SELF ASSEMBLY;

ANGIOGENESIS; BASELINE VALUES; CELL DIFFERENTIATION; CELLULAR BEHAVIORS; GROWTH FACTOR; HUMAN ENDOTHELIAL CELLS; IN-VITRO; OSTEOBLAST-LIKE CELLS; OSTEOGENIC DIFFERENTIATION; PLATELET-DERIVED GROWTH FACTORS; PLATELET-RICH PLASMA; PRIMARY CELLS; TRANSFORMING GROWTH FACTOR BETA; TUBE FORMATION; VASCULAR ENDOTHELIAL GROWTH FACTOR; VOLUME PERCENTAGE; WHOLE BLOOD;

CELL CULTURE;

RATTUS;

ALKALINE PHOSPHATASE; CALCIUM;

ANIMAL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; MALE; METABOLISM; OSTEOBLAST; RAT; THROMBOCYTE RICH PLASMA; WISTAR RAT;

ALKALINE PHOSPHATASE; ANIMALS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; MALE; OSTEOBLASTS; PLATELET-RICH PLASMA; RATS; RATS, WISTAR;

EID: 77957671537     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0832     Document Type: Article

References (62)

1. Kanno, T., Takahashi, T., Tsujisawa, T., Ariyoshi, W., and Nishihara, T. Platelet-rich plasma enhances human osteoblast-like cell proliferation and differentiation. J Oral Maxillofac Surg 63, 362, 2005.
2. Marx, R.E., and Garg, A.K. Dental and Craniofacial Applications of Platelet-Rich Plasma. Chicago, IL: Quintessence Publishing Co, Inc., 2005.
3. Pierce, G.F., Mustoe, T.A., Lingelbach, J., Masakowski, V.R., Griffin, G.L., Senior, R.M., et al. Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms. J Cell Biol 109, 429, 1989.
4. Marx, E., Carlson, E.R., Echstaedt, R.M., Schimmele, S.R., Strauss, J.E., and Georgeff, K.R. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg Med Oral Pathol Oral Radiol Endod 85, 638, 1998.
5. Merkx, M.A.W., Fennis, J.P.M., Verhagen, C.M., and Stoe-linga, P.J.W. Reconstruction of the mandible using pre-shaped 2.3mm titanium plates, autogenous particulate cortico-cancellous bone grafts and platelet rich plasma: a report on eight patients. Int J Oral Maxillofac Surg 33, 733, 2004.
6. Simon, E.N.M., Merkx, M.A.W., Shubi, F.M., Kalyanyama, B.M., and Stoelinga, P.J.W. Reconstruction of the mandible after ablative surgery for the treatment of aggressive, benign odontogenic tumours in Tanzania: a preliminary study. Int J Oral Maxillofac Surg 35, 421, 2006.
7. Thorn, J.J., Weis-Fogh, S.U., and Andersen, M. Autologous fibrin glue with growth factors in reconstructive maxillofa-cial surgery. Int J Oral Maxillofac Surg 33, 95, 2004.
8. Aghaloo, T.L., Moy, P.K., and Freymiller, E.G. Investigation of platelet-rich plasma in rabbit cranial defects: a pilot study. J Oral Maxillofac Surg 60, 1176, 2002.
9. Choi, B.H., Im, C.J., Huh, J.Y., Suh, J.J., and Lee, S.H. Effect of platelet-rich plasma on bone regeneration in autogenous bone graft. Int J Oral Maxillofac Surg 33, 56, 2004.
10. Fennis, J.P.M., Stoelinga, P.J.W., and Jansen, J.A. Mandi-bular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet-rich plasma in goats. Int J Oral Maxillofac Surg 33, 48, 2004.
11. Kim, S.G., Chung, C., and Kim, Y. Use of particulate dentin-plaster of paris combination with/without platelet-rich plasma in the treatment of bone defects around implants. Int J Oral Maxillofac Implants 17, 86, 2002.
12. Mooren, R.E.C.M., Merkx, M.A.W., Bronkhorst, E.M., Jan-sen, J.A., and Stoelinga, P.J.W. The effect of platelet-rich plasma on early and late bone healing: an experimental study in goats. In J Oral Maxillofac Surg 36, 626, 2007.
13. Plachokova, A.S., Van den Dolder, J., Stoelinga, P.J., and Jansen, J.A. Early effect of platelet-rich plasma on bone healing in combination with an osteoconductive material in rat cranial defects. Clin Oral Implants Res 18, 244, 2007.
14. Schlegel, K.A., Kloss, F.R., Kessler, P., Schultze-Mosgau, S., Nkenke, E., and Wiltfang, J. Bone conditioning to enhance implant osseointegration: an experimental study in pigs. Int J Oral Maxillofac Implants 18, 505, 2003.
15. Schlegel, K.A., Donath, K., Rupprecht, S., Falk, S., Zimmer-mann, R., Felszeghy, E., et al. De novo bone formation using bovine collagen and platelet-rich plasma. Biomaterials 25, 5387, 2004.
16. Wiltfang, J., Kloss, F.R., Kessler, P., Nkenke, E., Schultze-Mosgau, S., Zimmermann, R., et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects: an animal experiment. Clin Oral Implants Res 15, 187, 2004.
17. Zechner, W., Tangl, S., Tepper, G., Fü rst, G., Bernhart, T., Haas, R., et al. Influence of platelet-rich plasma on osseous healing of dental implants: a histologic and histomorpho-metric study in minipigs. Int J Oral Maxillofac Implants 18, 15, 2003.
18. Akeda, K., An, H.S., Pichika, R., Attawia, M., Thonar, E.J.M.A., Lenz, M.E., et al. Platelet-rich plasma (PRP) stimulates the extracellular matrix metabolism of porcine nucleus pulposus and annulus fibrosus cells cultured in alginate beads. Spine 31, 959, 2006.
19. Anitua, E., Andia, I., Sanchez, M., Azofra, J., Del Mar Zal-duendo, M., De la Fuente, M., et al. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res 23, 281, 2005.
20. Annunziata, M., Oliva, A., Buonaiuto, C., Di Feo, A., Di Pasquale, R., Passaro, I., et al. In vitro cell-type specifica biological response of human periodontally related cells to platelet-rich plasma. J Periodontal Res 40, 489, 2005.
21. Arpornmaeklong, P., Kochel, M., Depprich, R., Kübler, N.R., and Würzler, K.K. Influence of platelet-rich plasma (PRP) on osteogenic differentiation of rat bone marrow stromal cells. An in vitro study. Int J Oral Maxillofac Surg 33, 60, 2004.
22. Celotti, F., Colciago, A., Negri-Cesi, P., Pravettoni, A., Za-ninetti, R., and Sacchi, M.C. Effect of platelet-rich plasma on migration and proliferation of SaOS-2 osteoblasts: role of platelet-derived growth factor and transforming growth factor-b. Wound Rep Reg 14, 195, 2006.
23. Choi, B.H., Zhu, S.J., Kim, B.Y., Huh, J.Y., Lee, S.H., and Jung, J.H. Effect of platelet-rich plasma (PRP) concentration on the viability and proliferation of alveolar bone cells: an in vitro study. Int J Maxillofac Surg 34, 420, 2005.
24. Doucet, C., Ernou, I., Zhang, Y., Llence, J., Begot, L., Holy, X., et al. Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 205, 228, 2005.
25. Ferreira, C.F., Gomes, M.C.C., Filho, J.S., Granjeiro, J.M., Simões, C.M.O., and Magini, R.S. Platelet-rich plasma influence on human osteoblasts growth. Clin Oral Implants Res 16, 456, 2005.
26. Graziani, F., Ivanovski, S., Cei, S., Ducci, F., Tonetti, M., and Gabriele, M. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin Oral Implants Res 17, 212, 2006.
27. Han, J., Meng, H.X., Tang, J.M., Li, S.L., Tang, Y., and Chen, Z.B. The effect of different platelet-rich plasma concentra-tions on proliferation and differentiation of human peri-odontal ligament cells in vitro. Cell Prolif 40, 241, 2007.
28. Hsu, C.-W., Yuan, K., and Tseng, C.-C. The negative effect of platelet-rich plasma on the growth of human cells is associated with secreted thrombospondin-1. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107, 185, 2009.
29. Ishida, K., Kuroda, R., Miwa, M., Tabata, Y., Hokugo, A., Kawamoto, T., et al. The regenerative effects of platelet-rich plasma on meniscal cells in vitro and its in vivo application with biodegradable gelatin hydrogel. Tissue Eng 13, 1103, 2007.
30. Kawase, T., Okuda, K., Saito, Y., Amizuka, N., Suzuki, H., and Yoshie, H. Platelet-rich plasma provides nucleus for mineralization in cultures of partially differentiated peri-odontal ligament cells. In Vitro Cell Dev Biol Anim 41, 171, 2005.
31. Kawase, T., Okuda, K., Saito, Y., and Yoshie, H. In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-b or platelet-derived growth factor. J Periodontol 76, 760, 2005.
32. Kilian, O., Flesch, I., Wenisch, S., Taborski, B., Jork, A., Schnettler, R., et al. Effects of platelet growth factors on human mesenchymal stem cells and human endothelial cells in vitro. Eur J Med Res 9, 337, 2004.
33. Liu, Y., Kalén, A., Risto, O., and Wahlström, O. Fibroblast proliferation due to exposure to a platelet concentrate in vitro is pH dependent. Wound Rep Reg 10, 336, 2002.
34. Liu, Y., Zhou, Y., Feng, H., Ma, G., and Ni, Y. Injectable tissue-engineered bone composed of human adipose-derived stromal cells and platelet-rich plasma. Biomaterials 29, 3338, 2008.
35. Lucarelli, E., Beccheroni, A., Donati, D., Sangiorgi, L., Cen-acchi, A., Del Vento, A.M., et al. Platelet-derived growth factors enhance proliferation of human stromal stem cells. Biomaterials 24, 3095, 2003.
36. Ogino, Y., Ayukawa, Y., Tsukiyama, Y., and Koyano, K. The effect of platelet-rich plasma on the cellular response of rat bone marrow cells in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100, 302, 2005.
37. Ogino, Y., Ayukawa, Y., Kukita, T., and Koyano, K. The contribution of platelet-derived growth factor, transforming growth factor-b1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101, 724, 2006.
38. Ogino, Y., Ayakawa, Y., Kukita, T., Atsuta, I., and Koyano, K. Platelet-rich plasma suppresses osteoclastogenesis by promoting the secretion of osteoprotegerin. J Periodontal Res 44, 217, 2009.
39. Okuda, K., Kawase, T., Momose, M., Murata, M., Saito, Y., Suzuki, H., et al. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-b and modulates the proliferation of periodontally related cells in vitro. J Periodontol 74, 849, 2003.
40. Oliva, A., Passaro, I., Di Pasquele, R., Di Feo, A., Criscuolo, M., Zappia, V., et al. Ex vivo expansion of bone marrow stromal cells by platelet-rich plasma: a promising strategy in maxillo-facial surgery. Int J Immunopathol Pharmacol 19, 45, 2006.
41. Pietramaggiori, G., Scherer, S.S., Mathews, J.C., Alperovich, M., Yang, H.-J., Neuwalder, J., et al. Healing modulation induced by freeze-dried platelet-rich plasma and micronized allogenic dermis in a diabetic wound model. Wound Rep Reg 16, 218, 2008.
42. Roussy, Y., Bertrand Duchesne, M.-P., and Gagnon, G. Activation of human platelet-rich plasma: effect on growth factors release, cell division and in vivo bone formation. Clin Oral Implants Res 18, 639, 2007.
43. Soffer, E., Ouhayoun, J., Dosquet, C., Meunier, A., and Anagnostou, F. Effects of platelet lysates on select bone cell functions. Clin Oral Implants Res 15, 581, 2004.
44. Uggeri, J., Belletti, S., Guizzardi, S., Poli, T., Cantarelli, S., Scandroglio, R., et al. Dose-dependent effects of platelet gel releasate on activities of human osteoblasts. J Periodontol 78, 1985, 2007.
45. van den Dolder, J., Mooren, R., Vloon, A.P.G., Stoelinga, P.J.W., and Jansen, J.A. Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells. Tissue Eng 12, 3067, 2006.
46. Weibrich, G., Gnoth, S.H., Otto, M., Reichert, T.E., and Wagner, W. Wachstumsstimulation von humanen osteo-blastenähnlichen Zellen durch Thrombozytenkonzentrate in vitro. Mund Kiefer GesichtsChir 6, 168, 2002.
47. Zaky, S.H., Ottonello, A., Strada, P., Cancedda, R., and Mastrogiacomo, M. Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineering. J Tissue Eng Regen Med 2, 472, 2008.
48. Slapnicka, J., Fassmann, A., Strasak, L., Augustin, P., and Vanek, J. Effects of activated and nonactivated platelet-rich plasma on proliferation of human osteoblasts in vitro. J Oral Maxillofac Surg 66, 297, 2008.
49. Maniatopoulos, C., Sodek, J., and Melcher, A.H. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 254, 317, 1998.
50. de Ruijter, J.E., ter Brugge, P.J., Dieudonné, S.C., van Vliet, S.J., Torensma, R., and Jansen, J.A. Analysis of integrin expression in U2OS cells cultured on various calcium phosphate ceramic substrates. Tissue Eng 7, 279, 2001.
51. van den Dolder, J., Bancroft, G.N., Sikavitsas, V.I., Spauwen, P.H., Jansen, J.A., and Mikos, A.G. Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A 64, 235, 2003.
52. Tomoyasu, A., Higashio, K., Kanomata, K., Goto, M., Ko-daira, K., Serizawa, H., et al. Platelet-rich plasma stimulates osteoblastic differentiation in the presence of BMPs. J Bio-chem Biophys Res Commun 361, 62, 2007.
53. Lu, H.H., Vo, J.M., Chin, H.S., Lin, J., Cozin, M., Tsay, R., et al. Controlled delivery of platelet-rich plasma-derived growth factors for bone formation. J Biomed Mater Res A 86, 1128, 2008.
54. Cenni, E., Perut, F., Ciapetti, G., Savarino, L., Dallari, D., Cenacchi, A., et al. In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering. J Mater Sci Mater Med 20, 45, 2009.
55. Krasna, K., Domanovic, D., Tomsic, A., Svajger, U., and Jeras, M. Platelet gel stimulates proliferation of human dermal fibroblasts in vitro. Acta Dermatovenerol APA 3,16, 2007.
56. Marx, R.E. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg 62, 489, 2004.
57. Han, B., Woodell-May, J., Ponticiello, M., Yang, Z., and Nimni, M. The effect of thrombin activation of platelet-rich plasma on demineralized bone matrix osteoinductivity. J Bone Joint Surg Am 91, 1459, 2009.
58. Huang, Q., Wang, Y.D., Wu, T., Jiang, S., Hu, Y.L., and Pei, G.X. Preliminary separation of the growth factors in platelet-rich plasma: effects on the proliferation of human marrow-derived mesenchymal stem cells. Chin Med J (Engl) 122, 83, 2009.
59. BD BioCoat™. Angiogenesis System-Endothelial Cell Tube Formation: Product Specification Sheet. Bedford: BD Bio-sciences Discovery Labware, 2006.
60. Frechette, J.P., Martineau, I., and Gagnon, G. Platelet-rich plasmas: growth factor content and roles in wound healing. Dent Res 84, 434, 2005.
61. Hofmann, A., Ritz, U., Verrier, S., Eglin, D., Alini, M., Fuchs, S., et al. The effect of human osteoblasts on proliferation and neo-vessel formation of human umbilicial vein endothelial cells in a long-term 3D co-culture on polyurethane scaffolds. Biomaterials 29, 4217, 2008.
62. Intini, G. The use of platelet-rich plasma in bone reconstruction therapy. Biomaterials 30, 4956, 2009.