A new in vitro screening bioassay for the ecotoxicological evaluation of the estrogenic responses of environmental chemicals using roach (Rutilus rutilus) liver explant culture

Environmental Toxicology

Volumn 25, Issue 5, 2010, Pages 510-516

  Gerbron, Marie ^a   Geraudie, Perrine ^a   Rotchell, Jeanette ^b   Minier, Christophe ^a  

^a Université du Havre   (France)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Explant culture; Liver; Roach; Rutilus rutilus; Vitellogenin

Indexed keywords

4-NONYLPHENOL; ACTIVE COMPOUNDS; ANTI-ESTROGENIC; BISPHENOL A; BUTYLPARABEN; CELL VIABILITY; DOSE-DEPENDENT; ECOTOXICOLOGICAL; EFFECTIVE CONCENTRATION; ENDOCRINE DISRUPTING CHEMICALS; ENDOCRINE DISRUPTING COMPOUND; ENVIRONMENTAL CHEMICALS; ENVIRONMENTAL POLLUTANTS; ESTERASE ACTIVITIES; ESTROGENICITY; ETHYNYLESTRADIOL; EXPLANT CULTURE; FLUORESCEIN DIACETATE; IN-VITRO; LIVER EXPLANTS; MODEL COMPOUND; REPRODUCTIVE SYSTEMS; ROACH; RUTILUS RUTILUS; SCIENTIFIC COMMUNITY; SCREENING METHODS; TAMOXIFEN; TEST SYSTEMS; TESTING METHOD; VITELLOGENIN;

CELL CULTURE; CHEMICALS; ENDOCRINOLOGY; LIVER; PHENOLS;

BIOASSAY;

4 NONYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; BUTYL PARABEN; ENVIRONMENTAL CHEMICAL; ESTERASE; ESTRADIOL; ESTROGEN DERIVATIVE; ETHINYLESTRADIOL; FLUORESCEIN DIACETATE; TAMOXIFEN; VITELLOGENIN;

BIOASSAY; CYPRINID; DOSE-RESPONSE RELATIONSHIP; ECOTOXICOLOGY; ENDOCRINOLOGY; METABOLITE; ORGANIC POLLUTANT; REPRODUCTIVE PRODUCTIVITY; SENSITIVITY ANALYSIS; SEX HORMONE; TOXICITY TEST;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL VIABILITY; CONTROLLED STUDY; ECOTOXICITY; ENZYME ACTIVITY; EXPLANT; FISH; IN VITRO STUDY; LIVER CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RUTILUS RUTILUS; SCREENING TEST;

ANIMALS; BIOLOGICAL ASSAY; CARBOXYLIC ESTER HYDROLASES; CYPRINIDAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ECOTOXICOLOGY; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; ESTROGEN RECEPTOR MODULATORS; ESTROGENS; LIVER; ORGAN CULTURE TECHNIQUES; PHENOLS; VITELLOGENINS;

RUTILUS RUTILUS;

EID: 77957665991     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20596     Document Type: Article

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