Validation of an ex vivo Xenopus liver slice bioassay for environmental estrogens and estrogen mimics

Ecotoxicology and Environmental Safety

Volumn 53, Issue 1, 2002, Pages 178-187

  Hurter, E ^a   Pool, E J ^a   Van Wyk, J H ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Biomarker; ELISA; Endocrine disruption; Environmental; Estrogens; Ex vivo liver; Vitellogenin

Indexed keywords

BIOLOGICAL MARKER; ESTROGEN; VITELLOGENIN; WATER;

ECOTOXICOLOGY;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTAMINATION; CONTROLLED STUDY; ENVIRONMENT; ESTROGEN ACTIVITY; HORMONE ACTION; HORMONE DETERMINATION; IN VIVO STUDY; LAKE; LIVER; NONHUMAN; SENSITIZATION; SEWAGE EFFLUENT; TISSUE CULTURE; TISSUE SLICE; VALIDATION PROCESS; WATER SAMPLING; XENOPUS;

ANIMALIA;

EID: 0036736325     PISSN: 01476513     EISSN: None     Source Type: Journal    
DOI: 10.1006/eesa.2002.2252     Document Type: Article

References (35)

1. Overview of a workshop on screening methods for detecting potential (anti-) estrogenic/androgenic chemicals in wildlife
2. Changes in the affinity of estrogen and androgen receptors accompanying changes in receptor abundance in brown and rainbow trout
3. Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins
4. Estrogens in unexpected places: Possible implications for researchers and consumers
5. Eestrogenic effects of organic environmental extracts with the trout hepatocyte vitellogenin assay
6. Exestrogens: Mechanisms of action and strategies for identification and assessment
7. Direct induction by estradiol of vitellogenin synthesis in organ cultures of male X. laevis liver
8. Serum vitellogenin levels and reproductive impairment of male Japanese medaka (Oryzias latipes) exposed to 4-tert-octylphenol
9. Endocrine-disrupting contaminants and reproduction: Lessons from the study of wildlife
10. Estrogenic potency of effluent from two sewage treatment works in the United Kingdom
11. Universal assay of vitellogenin as biomarker for environmental estrogens
12. Estrogen dependence of synthesis and secretion of apolipoprotein B-containing lipoproteins in the chicken hepatopa cell line, LMH-2A
13. Regulation of vitellogenesis in reptiles
14. Vitellogenesis as a biomarker of reproductive disruption by xenobiotics
15. Amphibians as a model to study endocrine disruptors: II. Estrogenic activity of environmental chemicals in vitro and in vivo
16. Techniques for the detection of estrogenicity
17. Amphibians as a model to study endocrine disruptors: I. Environmental pollution and estrogen receptor binding
18. Vitellogenin as a biomarker for xenobiotic estrogens in an amphibian model system
19. Vitellogenin induction by xenobiotic estrogens in the Red-eared turtle and African clawed frog
20. Estradiol-binding molecules in the hepatocytes of the female water frog, Rana esculenta, and plasma estradiol and vitellogenin levels during the reproductive cycle
21. Estrogen-binding sites in the liver of sexually mature male and female brown trout, Salmo trutto (L)
22. Estrone interaction with the rat uterus: In vitro response and nuclear uptake
23. Phytestrogens and anthropogenic estrogenic compounds
24. The pesticide endosulphan, toxaphene and dieldrin have estrogenic effects on human estrogen-sensitive cells
25. The E-screen assay as a tool to identify estrogens: An update on estrogenic environmental pollutants
26. Feminized responses in fish to environmental estrogens
27. Vitellogenesis as biomarker for estrogenic contamination of the aquatic environment
28. Octylphenol induces vitellogenin production and cell death in fish hepatocytes
29. Studies on amphibian yolk
30. Environmentally persistent alkylphenolic compounds are estrogenic