Development of simultaneous gas chromatography-mass spectrometric and liquid chromatography-electrospray ionization mass spectrometric determination method for the new designer drugs, N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP) and their main metabolites in urine

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 819, Issue 2, 2005, Pages 315-322

  Tsutsumi, Hiroe ^a   Katagi, Munehiro ^a   Miki, Akihiro ^a   Shima, Noriaki ^a   Kamata, Tooru ^a   Nishikawa, Mayumi ^a   Nakajima, Kunio ^a   Tsuchihashi, Hitoshi ^a  

^a Chuo ward   (Japan)

Author keywords

1 (3 Trifluoromethylphenyl)piperazine; BZP; GC MS; Hydroxy 1 (3 trifluoromethylphenyl) piperazine; Hydroxy N benzylpiperazine; LC ESI MS; N Benzylpiperazine; TFMPP

Indexed keywords

CONCENTRATION (PROCESS); DERIVATIVES; EXTRACTION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IONIZATION; MASS SPECTROMETRY; METABOLITES; PH EFFECTS;

ELECTROSPRAY IONIZATION; FORENSIC TOXICOLOGY; LINEAR CALIBRATION CURVES; SELECTED ION MONITORING (SIM); SOLID PHASE EXTRACTION;

DRUG PRODUCTS;

1 (3 TRIFLUOROMETHYLPHENYL)PIPERAZINE; 3' HYDROXY N BENZYLPIPERAZINE; 4 HYDROXY N BENZYLPIPERAZINE; ACETONITRILE; AMMONIUM ACETATE; BUFFER; DRUG METABOLITE; N BENZYLPIPERAZINE; PIPERAZINE DERIVATIVE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ACCURACY; ACIDITY; ARTICLE; CALIBRATION; COLUMN CHROMATOGRAPHY; DERIVATIZATION; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETRY; PRIORITY JOURNAL; RELIABILITY; SOLID PHASE EXTRACTION; URINE;

EID: 17144420495     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2005.02.016     Document Type: Article

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