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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 19, 2010, Pages 5617-5622

Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators

(5) Bridges, Thomas M a,c Kennedy, J Phillip b Hopkins, Corey R a,c Conn, P Jeffrey a,c Lindsley, Craig W a,b,c

a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE (United States)

b VANDERBILT UNIVERSITY (United States)

c VANDERBILT UNIVERSITY MEDICAL CENTER (United States)

Author keywords

Allosteric; M5; mAChR; PAM

Indexed keywords

ETHER DERIVATIVE; LEAD; MUSCARINIC M5 RECEPTOR;

ALLOSTERISM; ARTICLE; PHYSICAL CHEMISTRY; SYNTHESIS;

ALLOSTERIC REGULATION; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ETHERS; HETEROCYCLIC COMPOUNDS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; RECEPTORS, MUSCARINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77957597974 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.08.042 Document Type: Article

Times cited : (27)

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- For information on the ancillary pharmacology panel see the Lead Profiling Screen at
- For information on the ancillary pharmacology panel see the Lead Profiling Screen at www.ricerca.com.

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