SCOPUS 정보 검색 플랫폼

Volumn 4, Issue 10, 2009, Pages 1600-1607

Synthesis and structure-activity relationships of allosteric potentiators of the M4 muscarinic acetylcholine receptor

(10) Kennedy, J Phillip a Bridges, Thomas M b Gentry, Patrick R b Brogan, John T a Kane, Alexander S b Jones, Carrie K b,c Brady, Ashley E b Shirey, Jana K b Conn, P Jeffrey b Lindsley, Craig W a,b

a VANDERBILT UNIVERSITY (United States)

b VANDERBILT UNIVERSITY MEDICAL CENTER (United States)

c DEPARTMENT OF VETERANS AFFAIRS (United States)

Author keywords

Allosteric; Muscarinic; Potentiators; Receptors; Schizophrenia; Structure activity relationships

Indexed keywords

2 CYANOTHIOACETAMIDE; 3 AMINOCROTONITRILE; ACETYLCHOLINE; ALPHA CHLORO PARA METHOXYBENZAMIDE; AMINE; CALCIUM ION; CHLOROACETIC ACID ETHYL ESTER; DRUG METABOLITE; ETHER; ETHYLACETOACETATE; HISTAMINE H3 RECEPTOR ANTAGONIST; MORPHOLINE DERIVATIVE; MUSCARINIC M4 RECEPTOR; PARA METHOXYBENZAMIDE; PYRIDONE DERIVATIVE; PYRROLIDINE DERIVATIVE; THIENO[3,2 C]PYRIDINE DERIVATIVE; THIENOPYRIDONE ETHYL ESTER; UNCLASSIFIED DRUG; VU 0152099; VU 0152100; VU 10010;

ALLOSTERISM; ARTICLE; CELL LINE; DRUG ACTIVITY; DRUG EFFECT; DRUG EFFICACY; HUMAN; INTERMETHOD COMPARISON; LOCOMOTION; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; SCHIZOPHRENIA; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALLOSTERIC REGULATION; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; MUSCARINIC AGONISTS; RECEPTOR, MUSCARINIC M4; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70349769359 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200900231 Document Type: Article

Times cited : (38)

References (22)

1
- 0023191072
- T. I. Bonner, N. J. Buckley, A. C. Young, M. R. Brann, Science 1987, 237, 527-532.
- (1987) Science , vol.237 , pp. 527-532
- Bonner, T.I.¹ Buckley, N.J.² Young, A.C.³ Brann, M.R.⁴

2
- 0024039146
- T. I. Bonner, A. C. Young, M. R. Brann, N. J. Buckley, Neuron 1988, 1, 403-410.
- (1988) Neuron , vol.1 , pp. 403-410
- Bonner, T.I.¹ Young, A.C.² Brann, M.R.³ Buckley, N.J.⁴

3
- 0027208248
- M. P. Caulfield, Pharmacol. Ther. 1993, 58, 319-379.
- (1993) Pharmacol. Ther. , vol.58 , pp. 319-379
- Caulfield, M.P.¹

4
- 0037375485
- F. P. Bymaster, D. L. McKinzie, C. C. Felder, J. Wess, Neurochem. Res. 2003, 28, 437-442.
- (2003) Neurochem. Res. , vol.28 , pp. 437-442
- Bymaster, F.P.¹ McKinzie, D.L.² Felder, C.C.³ Wess, J.⁴

5
- 0037470642
- J. Wess, A. Duttaroy, W. Zhang, J. Gomeza, Y. Cui, T. Miyakawa, F. P. Bymaster, L. McKinzie, C. C. Felder, K. G. Lamping, F. M. Faraci, C. Deng, M. Yamada, Life Sci. 2003, 72, 2047-2054.
- (2003) Life Sci. , vol.72 , pp. 2047-2054
- Wess, J.¹ Duttaroy, A.² Zhang, W.³ Gomeza, J.⁴ Cui, Y.⁵ Miyakawa, T.⁶ Bymaster, F.P.⁷ McKinzie, L.⁸ Felder, C.C.⁹ Lamping, K.G.¹⁰ Faraci, F.M.¹¹ Deng, C.¹² Yamada, M.¹³

6
- 24944467463
- J. W. Clader, Y. Wang, Curr Pharm Des 2005, 11, 3353-3361.
- (2005) Curr Pharm Des , vol.11 , pp. 3353-3361
- Clader, J.W.¹ Wang, Y.²

7
- 38349193123
- C. J. Langmead, J. Watson, C. Reavill, Pharmacol. Ther. 2008, 117, 232-243.
- (2008) Pharmacol. Ther. , vol.117 , pp. 232-243
- Langmead, C.J.¹ Watson, J.² Reavill, C.³

8
- 34548362105
- J. Wess, R. M. Eglen, D. Gautam, Nat. Rev. Drug Discovery 2007, 6, 721-733.
- (2007) Nat. Rev. Drug Discovery , vol.6 , pp. 721-733
- Wess, J.¹ Eglen, R.M.² Gautam, D.³

9
- 0034676312
- C. C. Felder, F. P. Bymaster, J. Ward, N. DeLapp, J. Med. Chem. 2000, 43, 4333-4353.
- (2000) J. Med. Chem. , vol.43 , pp. 4333-4353
- Felder, C.C.¹ Bymaster, F.P.² Ward, J.³ DeLapp, N.⁴

10
- 57349113845
- A. E. Brady, C. K. Jones, T. M. Bridges, J. P. Kennedy, A. D. Thompson, J. U. Heiman, M. L. Breininger, P. R. Gentry, H. Yin, S. B. Jadhav, J. K. Shirey, P. J. Conn, C. W. Lindsley, J. Pharmacol. Exp. Ther. 2008, 327, 941-953.
- (2008) J. Pharmacol. Exp. Ther. , vol.327 , pp. 941-953
- Brady, A.E.¹ Jones, C.K.² Bridges, T.M.³ Kennedy, J.P.⁴ Thompson, A.D.⁵ Heiman, J.U.⁶ Breininger, M.L.⁷ Gentry, P.R.⁸ Yin, H.⁹ Jadhav, S.B.¹⁰ Shirey, J.K.¹¹ Conn, P.J.¹² Lindsley, C.W.¹³

11
- 55249118679
- C. K. Jones, A. E. Brady, A. A. Davis, Z. Xiang, M. Bubser, M. N. Tantawy, A. S. Kane, T. M. Bridges, J. P. Kennedy, S. R. Bradley, T. E. Peterson, M. S. Ansari, R. M. Baldwin, R. M. Kessler, A. Y. Deutch, J. J. Lah, A. I. Levey, C. W. Lindsley, P. J. Conn, J. Neurosci. 2008, 28, 10422-10433.
- (2008) J. Neurosci. , vol.28 , pp. 10422-10433
- Jones, C.K.¹ Brady, A.E.² Davis, A.A.³ Xiang, Z.⁴ Bubser, M.⁵ Tantawy, M.N.⁶ Kane, A.S.⁷ Bridges, T.M.⁸ Kennedy, J.P.⁹ Bradley, S.R.¹⁰ Peterson, T.E.¹¹ Ansari, M.S.¹² Baldwin, R.M.¹³ Kessler, R.M.¹⁴ Deutch, A.Y.¹⁵ Lah, J.J.¹⁶ Levey, A.I.¹⁷ Lindsley, C.W.¹⁸ Conn, P.J.¹⁹

12
- 37249054670
- J. K. Shirey, Z. Xiang, D. Orton, A. E. Brady, K. A. Johnson, R. Williams, J. E. Ayala, A. L. Rodriguez, J. Wess, D. Weaver, C. M. Niswender, P. J. Conn, Nat. Chem. Biol. 2008, 4, 42-50.
- (2008) Nat. Chem. Biol. , vol.4 , pp. 42-50
- Shirey, J.K.¹ Xiang, Z.² Orton, D.³ Brady, A.E.⁴ Johnson, K.A.⁵ Williams, R.⁶ Ayala, J.E.⁷ Rodriguez, A.L.⁸ Wess, J.⁹ Weaver, D.¹⁰ Niswender, C.M.¹¹ Conn, P.J.¹²

13
- 46249084634
- C. J. Langmead, N. E. Austin, C. L. Branch, J. T. Brown, K. A. Buchanan, C. H. Davies, I. T. Forbes, V. A. Fry, J. J. Hagan, H. J. Herdon, G. A. Jones, R. Jeggo, J. N. Kew, A. Mazzali, R. Melarange, N. Patel, J. Pardoe, A. D. Randall, C. Roberts, A. Roopun, K. R. Starr, A. Teriakidis, M. D. Wood, M. Whittington, Z. Wu, J. Watson, Br. J. Pharmacol. 2008, 154, 1104-1115.
- (2008) Br. J. Pharmacol. , vol.154 , pp. 1104-1115
- Langmead, C.J.¹ Austin, N.E.² Branch, C.L.³ Brown, J.T.⁴ Buchanan, K.A.⁵ Davies, C.H.⁶ Forbes, I.T.⁷ Fry, V.A.⁸ Hagan, J.J.⁹ Herdon, H.J.¹⁰ Jones, G.A.¹¹ Jeggo, R.¹² Kew, J.N.¹³ Mazzali, A.¹⁴ Melarange, R.¹⁵ Patel, N.¹⁶ Pardoe, J.¹⁷ Randall, A.D.¹⁸ Roberts, C.¹⁹ Roopun, A.²⁰ more..

14
- 0036259109
- T. A. Spalding, C. Trotter, N. Skjaerbaek, T. L. Messier, E. A. Currier, E. S. Burstein, D. Li, U. Hacksell, M. R. Brann, Mol. Pharmacol. 2002, 61, 1297-1302.
- (2002) Mol. Pharmacol. , vol.61 , pp. 1297-1302
- Spalding, T.A.¹ Trotter, C.² Skjaerbaek, N.³ Messier, T.L.⁴ Currier, E.A.⁵ Burstein, E.S.⁶ Li, D.⁷ Hacksell, U.⁸ Brann, M.R.⁹

15
- 53449093828
- T. M. Bridges, C. W. Lindsley, ACS Chem. Biol. 2008, 3, 530-541.
- (2008) ACS Chem. Biol. , vol.3 , pp. 530-541
- Bridges, T.M.¹ Lindsley, C.W.²

16
- 33746375386
- F. A. H. Abu-Shanab, A. Gaber, H. Mousa, A. S. Sayed, J. Sulfur Chem. 2006, 27, 293-305.
- (2006) J. Sulfur Chem. , vol.27 , pp. 293-305
- Abu-Shanab, F.A.H.¹ Gaber, A.² Mousa, H.³ Sayed, A.S.⁴

17
- 70349771657
- V. P. S. Litvinov, A. Yu, V. K. Promonenkov, L. A. Rodinovskaya, A. M. Shestopalov, Mortikov, V. Yu, Seriya Khimicheskaya 1984, 8, 1869-1870.
- (1984) Seriya Khimicheskaya , vol.8 , pp. 1869-1870
- Litvinov, V.P.S.¹ Yu, A.² Promonenkov, V.K.³ Rodinovskaya, L.A.⁴ Shestopalov, A.M.⁵ Yu, M.V.⁶

18
- 70349760414
- note
- See Supporting Information for full details.

19
- 70349780262
- (Eli Lilly & Co., Indianapolis, USA), WO/ 2006/047124
- R. E. Almudena, D. W. Hilliard, (Eli Lilly & Co., Indianapolis, USA), WO/ 2006/047124, 2006.
- (2006)
- Almudena, R.E.¹ Hilliard, D.W.²

20
- 58149193205
- P. J. Conn, A. Christopolous, C. W. Lindsley, Nat. Rev. Drug Discovery 2009, 8, 41-54.
- (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 41-54
- Conn, P.J.¹ Christopolous, A.² Lindsley, C.W.³

21
- 29144437722
- S. Celanire, M. Wijtmans, P. Talaga, R. Leurs, J. P. de Esch, Drug Discovery Today 2005, 10, 1613-1627.
- (2005) Drug Discovery Today , vol.10 , pp. 1613-1627
- Celanire, S.¹ Wijtmans, M.² Talaga, P.³ Leurs, R.⁴ De Esch, J.P.⁵

22
- 47249148399
- T. A. Esbenshade, K. E. Brownman, R. S. Bitner, M. Strakhova, M. D. Cowart, J. D. Brioni, Br. J. Pharmacol. 2008, 154, 1166-1181.
- (2008) Br. J. Pharmacol. , vol.154 , pp. 1166-1181
- Esbenshade, T.A.¹ Brownman, K.E.² Bitner, R.S.³ Strakhova, M.⁴ Cowart, M.D.⁵ Brioni, J.D.⁶

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.