Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 19, 2010, Pages 5936-5938

  Phillips, Joshua B ^a   Smith, Adrienne E ^b   Kusche, Brian R ^b   Bessette Jr , Bradley A ^b   Swain III, P Whitney ^a   Bergmeier, Stephen C ^b   McMills, Mark C ^b   Wright, Dennis L ^b   Priestley, Nigel D ^a  

^a UNIVERSITY OF MONTANA   (United States)

^b Promiliad Biopharma   (United States)

Author keywords

Antibiotic; Biosynthesis; Nonactin; Triazoloester

Indexed keywords

ANTIINFECTIVE AGENT; MACROLIDE; NATURAL PRODUCT; NONACTIN; PBP 14E1; PBP 14E5; TRIAZOLE; UNCLASSIFIED DRUG;

ARTICLE; BACTERICIDAL ACTIVITY; CHEMICAL ANALYSIS; COMBINATORIAL LIBRARY; DRUG STRUCTURE; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; GRAM POSITIVE BACTERIUM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN;

ANTI-BACTERIAL AGENTS; BIOLOGICAL PRODUCTS; DRUG RESISTANCE, BACTERIAL; ENTEROCOCCUS FAECALIS; GRAM-POSITIVE BACTERIA; MACROLIDES; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; STEREOISOMERISM; TRIAZOLES; VANCOMYCIN;

ENTEROCOCCUS FAECALIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 77957580447     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.06.146     Document Type: Article

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