Methylxanthines and ryanodine receptor channels

Handbook of Experimental Pharmacology

Volumn 200, Issue , 2011, Pages 135-150

  Guerreiro, Serge ^a,b,c   Marien, Marc ^d   Michel, Patrick P ^a  

^a INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^b INSERM   (France)

^c CNRS   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Calcium; Methylxanthines; Muscle cell contraction; Neuroprotection; Neurotransmitter release; Ryanodine receptors

Indexed keywords

1 METHYLXANTHINE; 1,3 DIMETHYL 7 (5 ETHYLCARBOXYPENTYL)XANTHINE; 1,3 DIMETHYL 7 (7 HYDROXYOCTYL)XANTHINE; 1,9 DIMETHYLXANTHINE; 3 METHYL 7 (7 OXOOCTYL) 1 PROPARGYLXANTHINE; 3,9 DIMETHYLXANTHINE; 7 ISOBUTYL 1 METHYLXANTHINE; 7 METHYLXANTHINE; CAFFEINE; CALCIUM ION; CHLOROCRESOL; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; ISOBUTYLMETHYLXANTHINE; METHYLXANTHINE; NICOTINE; PARAXANTHINE; RYANODINE; RYANODINE RECEPTOR; RYANODINE RECEPTOR 1; RYANODINE RECEPTOR 2; RYANODINE RECEPTOR 3; THEOBROMINE; THEOPHYLLINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

BINDING AFFINITY; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELL STIMULATION; CELL SURVIVAL; CONCENTRATION RESPONSE; DIET SUPPLEMENTATION; DOPAMINE RELEASE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; ENDOPLASMIC RETICULUM; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MUSCLE FIBER CONTRACTION; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; RISK REDUCTION;

ANIMALS; CAFFEINE; CALCIUM; ENDOPLASMIC RETICULUM; HUMANS; MUSCLE CONTRACTION; NEURONS; NEUROTRANSMITTER AGENTS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; XANTHINES;

EID: 77957564931     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-13443-2_5     Document Type: Review

References (75)

1. Arnaud M (2010) Pharmacokinetics and metabolism of natural methylxanthines in animal and man. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
2. Ascherio A, Zhang SM, Hernan MA, Kawachi I, Colditz GA, Speizer FE, Willett WC (2001) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann Neurol 50:56-63
3. Ashihara H, Kato M, Crozier A (2010) Distribution, biosynthesis and catabolism of methylxanthines in plants. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
4. Birkett DJ, Dahlqvist R, Miners JO, Lelo A, Billing B (1985) Comparison of theophylline and theobromine metabolism in man. Drug Metab Dispos 13:725-728
5. Block BM, Barry SR, Faulkner JA (1992) Aminophylline increases submaximum power but not intrinsic velocity of shortening of frog muscle. J Appl Physiol 73:71-74
6. Bruton JD, Lemmens R, Shi CL, Persson-Sjögren S, Westerblad H, Ahmed M, Pyne NJ, Frame M, Furman BL, Islam MS (2003) Ryanodine receptors of pancreatic β-cells mediate a distinct context-dependent signal for insulin secretion. FASEB J 17:301-303
7. 2+ release channel. J Biol Chem 267:23560-23567
8. 2+-release by methylxanthine analogues. J Med Chem 42:2527-2534
9. 2+ channels contrasted with strong regulation of axonal dopamine release. J Neurochem 96:645-655
10. Connett RJ, Ugol LM, Hammack MJ, Hays ET (1983) Twitch potentiation and caffeine contractures in isolated rat soleus muscle. Comp Biochem Physiol C 74:349-354
11. Conway D, Sakai T (1960) Caffeine contracture. Proc Natl Acad Sci USA 46:897-903
12. Daly JW (2007) Caffeine analogs: biomedical impact. Cell Mol Life Sci 64:2153-2169
13. 2+ release involving ryanodine receptors. Mol Pharmacol 52:1124-1130
14. + requires concurrent inactivation of NMDA or AMPA/kainate receptors. J Neurochem 78:163-174
15. 2+ release channels (ryanodine receptors). J Biol Chem 274:26120-26126
16. 2+ release. Biochem J 382 (Pt 2):557-564
17. Elbaz A, Moisan F (2008) Update in the epidemiology of Parkinson's disease. Curr Opin Neurol 21:454-460
18. Endo M (1977) Calcium release from the sarcoplasmic reticulum. Physiol Rev 57:71-108
19. Fabiato A (1983) Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum. Am J Physiol Cell Physiol 245: C1-C14
20. Ferré S, Guix T, Sallés J, Badia A, Parra P, Jané F, Herrera-Marschitz M, Ungerstedt U, Casas M (1990) Paraxanthine displaces the binding of [3H]SCH 23390 from rat striatal membranes. Eur J Pharmacol 179:295-299
21. Fessenden JD, Feng W, Pessah IN, Allen PD (2006) Amino acid residues Gln4020 and Lys4021 of the ryanodine receptor type 1 are required for activation by 4-chloro-m-cresol. J Biol Chem 281:21022-21031
22. Fill M, Copello JA (2002) Ryanodine receptor calcium release channels. Physiol Rev 82:893-922
23. Francis SH, Sekhar KR, Ke H, Corbin JD (2010) Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
24. Galante M, Marty A (2003) Presynaptic ryanodine-sensitive calcium stores contribute to evoked neurotransmitter release at the basket cell-Purkinje cell synapse. J Neurosci 23:11229-11234
25. 2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose. Science 253:1143-1146
26. Garaschuk O, Yaari Y, Konnerth A (1997) Release and sequestration of calcium by ryanodinesensitive stores in rat hippocampal neurones. J Physiol 502:13-30
27. Guerreiro S, Toulorge D, Hirsch E, Marien M, Sokoloff P, Michel PP (2008) Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol 74:980-989
28. 2+]i in skeletal muscle. J Appl Physiol 89:2312-2317
29. Herrmann-Frank A, Lüttgau HC, Stephenson DG (1999) Caffeine and excitation-contraction coupling in skeletal muscle: a stimulating story. J Muscle Res Cell Motil 20:223-237
30. 2+ channels in planar bilayers. Proc Natl Acad Sci USA 85:441-445
31. Islam MS, Leibiger I, Leibiger B, Rossi D, Sorrentino V, Ekström TJ, Westerblad H, Andrade FH, Berggren PO (1998) In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation. Proc Natl Acad Sci USA 95:6145-6150
32. Jacobson KA, Gao ZG (2006) Adenosine receptors as therapeutic targets. Nat Rev Drug Discov 5:247-264
33. Kano M, Garaschuk O, Verkhratsky A, Konnerth A (1995) Ryanodine receptor-mediated intracellular calcium release in rat cerebellar Purkinje neurones. J Physiol 487:1-16
34. Kelly E, Bailey CP, Henderson G (2008) Agonist-selective mechanisms of GPCR desensitization. Br J Pharmacol 153 (Suppl 1): S379-S388
35. 2+ release from fragmented sarcoplasmic reticulum: a comparison with skinned muscle fiber studies. J Biochem 92:1287-1296
36. 2+ activation of the ryanodine receptor. Biochem J 414:441-452
37. Kramer ER, Aron L, Ramakers GM, Seitz S, Zhuang X, Beyer K, Smidt MP, Klein R (2007) Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol 5: e39
38. Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D (1999) Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 46:598-605
39. Lee HC (1993) Potentiation of calcium-and caffeine-induced calcium release by cyclic ADP-ribose. J Biol Chem 268:293-299
40. 2+ release channel. Pharmacology 54:135-143
41. Love S, Plaha P, Patel NK, Hotton GR, Brooks DJ, Gill SS (2005) Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain. Nat Med 11:703-704
42. Magkos F, Kavouras SA (2005) Caffeine use in sports, pharmacokinetics in man, and cellular mechanisms of action. Crit Rev Food Sci Nutr 45:535-562
43. McGarry SJ, Williams AJ (1994) Adenosine discriminates between the caffeine and adenine nucleotide sites on the sheep cardiac sarcoplasmic reticulum calcium-release channel. J Membr Biol 137:169-177
44. McPherson PS, Kim YK, Valdivia H, Knudson CM, Takekura H, Franzini-Armstrong C, Coronado R, Campbell KP (1991) The brain ryanodine receptor: a caffeine-sensitive calcium release channel. Neuron 7:17-25
45. 2+, adenine nucleotide, and calmodulin. J Biol Chem 262:3065-3073
46. 2+ release channel of skeletal and cardiac sarcoplasmic reticulum. Mol Cell Biochem 82:59-65
47. Michel PP, Alvarez-Fischer D, Guerreiro S, Hild A, Hartmann A, Hirsch EC (2007) Role of activity-dependent mechanisms in the control of dopaminergic neuron survival. J Neurochem 101:289-297
48. 2+ release from skeletal sarcoplasmic reticulum. Role of monovalent ions. J Biol Chem 263:4228-4235
49. Näbauer M, Callewaert G, Cleemann L, Morad M (1989) Regulation of calcium release is gated by calcium current, not gating charge, in cardiac myocytes. Science 246:1640
50. Patel JC, Witkovsky P, Avshalumov MV, Rice ME (2009) Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release. J Neurosci 29:6568-6579
51. 2+, caffeine, and adenine nucleotides. Mol Pharmacol 31:232-238
52. Ritter M, Menon S, Zhao L, Xu S, Shelby J, Barry WH (2001) Functional importance and caffeine sensitivity of ryanodine receptors in primary lymphocytes. Int Immunopharmacol 1:339-347
53. 2+ release channel of skeletal muscle sarcoplasmic reticulum by caffeine and related compounds. Arch Biochem Biophys 267:75-86
54. Sääksjärvi K, Knekt P, Rissanen H, Laaksonen MA, Reunanen A, Männistö S (2008) Prospective study of coffee consumption and risk of Parkinson's disease. Eur J Clin Nutr 62:908-915
55. Salthun-Lassalle B, Hirsch EC, Wolfart J, Ruberg M, Michel PP (2004) Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels. J Neurosci 24:5922-5930
56. Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, Kubo M, Kawaguchi T, Tsunoda T, Watanabe M, Takeda A, Tomiyama H, Nakashima K, Hasegawa K, Obata F, Yoshikawa T, Kawakami H, Sakoda S, Yamamoto M, Hattori N, Murata M, Nakamura Y, Toda T (2009) Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet 41:1303-1307
57. Sharma G, Vijayaraghavan S (2003) Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing. Neuron 38:929-939
58. Sitsapesan R, Williams AJ (1990) Mechanisms of caffeine activation of single calcium-release channels of sheep cardiac sarcoplasmic reticulum. J Physiol 423:425-439 (Pubitemid 20137767)
59. 2+ release. Trends Pharmacol Sci 16:386-391
60. Smith AB, Cunnane TC (1996) Ryanodine-sensitive calcium stores involved in neurotransmitter release from sympathetic nerve terminals of the guinea-pig. J Physiol 497 (Pt 3):657-664
61. Sutko JL, Airey JA, Welch W, Ruest L (1997) The pharmacology of ryanodine and related compounds. Pharmacol Rev 49:53-98
62. Trueta C, Sánchez-Armass S, Morales MA, De-Miguel FF (2004) Calcium-induced calcium release contributes to somatic secretion of serotonin in leech Retzius neurons. J Neurobiol 61:309-316
63. Usachev Y, Verkhratsky A (1995) IBMX induces calcium release from intracellular stores in rat sensory neurones. Cell Calcium 17:197-206
64. Usachev Y, Shmigol A, Pronchuk N, Kostyuk P, Verkhratsky A (1993) Caffeine-induced calcium release from internal stores in cultured rat sensory neurons. Neuroscience 57:845-859
65. Veley VH, Waller AD (1910) On the comparative toxicity of theobromine and caffeine, as measured by their direct effect upon the contractility of isolated muscle. Proc R Soc Lond B Biol Sci 82:568-574
66. Verkhratsky A (2005) Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol Rev 85:201-279
67. 2+ release from the endoplasmic reticulum in honeybee photoreceptors. J Gen Physiol 105:537-567
68. 2+ release channel (ryanodine receptor) is crucial for channel activation and gating. J Biol Chem 279:3635-42
69. Wang SJ (2007) Caffeine facilitation of glutamate release from rat cerebral cortex nerve terminals (synaptosomes) through activation protein kinase C pathway: an interaction with presynaptic adenosine A1 receptors. Synapse 61:401-411
70. Wyskovsky W (1994) Caffeine-induced calcium oscillations in heavy-sarcoplasmic-reticulum vesicles from rabbit skeletal muscle. Eur J Biochem 221:317-325
71. 2+. Biophys J 75:2302-2312
72. Xu K, Xu YH, Chen JF, Schwarzschild MA (2010) Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease. Neuroscience 167:475-478
73. Xu K, Xu Y, Brown-Jermyn D, Chen JF, Ascherio A, Dluzen DE, Schwarzschild MA (2006) Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci 26:535-541
74. Zalk R, Lehnart SE, Marks AR (2007) Modulation of the ryanodine receptor and intracellular calcium. Annu Rev Biochem 76:367-385
75. 2+ channel/ryanodine receptor: modulation by endogenous effectors, drugs and disease states. Pharmacol Rev 49:1-51