Endothelial arginase II responds to pharmacological inhibition by elevation in protein level

Molecular and Cellular Biochemistry

Volumn 343, Issue 1-2, 2010, Pages 211-216

  Krotova, Karina ^a   Patel, Jawaharlal M ^a,b   Block, Edward R ^a,b   Zharikov, Sergey ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Arginase; Arginase inhibitors; Endothelium

Indexed keywords

ARGINASE; ARGINASE II; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN CONTENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ARGINASE; BASE SEQUENCE; BLOTTING, WESTERN; CELLS, CULTURED; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOTHELIUM, VASCULAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE;

EID: 77957549495     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0515-5     Document Type: Article

References (25)

1. T Gotoh M Araki M Mori 1997 Chromosomal localization of the human arginase II gene and tissue distribution of its mrnA Biochem Biophys Res Commun 233 487 491 1:CAS:528:DyaK2sXivVGqsr0%3D 10.1006/bbrc.1997.6473 9144563 (Pubitemid 27226654)
2. RS Sparkes GJ Dizikes I Klisak WW Grody T Mohandas C Heinzmann S Zollman AJ Lusis SD Cederbaum 1986 The gene for human liver arginase (ARG1) is assigned to chromosome band 6q23 Am J Hum Genet 39 186 193 1:CAS:528:DyaL28XlvVGitrs%3D 3752085
3. GY Wu SM Morris 1998 Arginine metabolism: nitric oxide and beyond Biochem J 336 1 17 1:CAS:528:DyaK1cXotVGltrs%3D 9806879
4. SM Morris Jr 2009 Recent advances in arginine metabolism: roles and regulation of the arginases Br J Pharmacol 157 922 930 10.1111/j.1476-5381.2009. 00278.x
5. W Durante FK Johnson RA Johnson 2007 Arginase: a critical regulator of nitric oxide synthesis and vascular function Clin Exp Pharmacol Physiol 34 906 911 1:CAS:528:DC%2BD2sXpslOjs7w%3D 10.1111/j.1440-1681.2007.04638.x 17645639 (Pubitemid 47083958)
6. M Munder 2009 Arginase: an emerging key player in the mammalian immune system Br J Pharmacol 158 638 651 1:CAS:528:DC%2BD1MXhsVSks7rI 10.1111/j.1476-5381.2009.00291.x 19764983
7. DW Christianson 2005 Arginase: structure, mechanism, and physiological role in male and female sexual arousal Acc Chem Res 38 191 201 1:CAS:528:DC%2BD2MXhtF2jsL4%3D 10.1021/ar040183k 15766238 (Pubitemid 40388098)
8. NN Kim JD Cox RF Baggio FA Emig SK Mistry SL Harper DW Speicher Morris M Sidney DE Ash A Traish DW Christianson 2001 Probing erectile function: S-(2-Boronoethyl)-l-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum Biochemistry 40 2678 2688 1:CAS:528:DC%2BD3MXnvVOgug%3D%3D 10.1021/bi002317h 11258879 (Pubitemid 32198270)
9. GM Buga R Singh S Pervin NE Rogers DA Schmitz CP Jenkinson SD Cederbaum LJ Ignarro 1996 Arginase activity in endothelial cells: inhibition by NG-hydroxy-l-arginine during high-output NO production Am J Physiol 271 H1988 H1998 1:CAS:528:DyaK28XntFylu7g%3D 8945918
10. JL Boucher J Custot S Vadon M Delaforge M Lepoivre JP Tenu A Yapo D Mansuy 1994 N[omega]-hydroxy-l-arginine, an intermediate in the l-arginine to nitric oxide pathway, is a strong inhibitor of liver and macrophage arginase Biochem Biophys Res Commun 203 1614 1621 1:CAS:528:DyaK2cXmt1Oju78%3D 10.1006/bbrc.1994.2371 7945311
11. J-P Tenu M Lepoivre C Moali M Brollo D Mansuy J-L Boucher 1999 Effects of the new arginase inhibitor N[omega]-hydroxy-nor-arginine on NO synthase activity in murine macrophages Nitric Oxide 3 427 438 1:CAS:528: DC%2BD3cXjsFyhtQ%3D%3D 10.1006/niox.1999.0255 10637120 (Pubitemid 30070642)
12. ER Block JM Patel NP Sheridan 1986 Endotoxin protects against hyperoxic decrease in membrane fluidity in endothelial cells but not in fibroblasts Lab Invest 54 146 153 1:CAS:528:DyaL28XhvVWnsbc%3D 3511321
13. MAK Markwell SM Haas LL Bieber NE Tolbert 1978 A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples Anal Biochem 87 206 210 1:CAS:528:DyaE1cXktF2mt7w%3D 10.1016/0003-2697(78)90586-9 98070
14. E Larson B Howlett A Jagendorf 1986 Artificial reductant enhancement of the Lowry method for protein determination Anal Biochem 155 243 248 1:CAS:528:DyaL28Xktlymurs%3D 10.1016/0003-2697(86)90432-X 3728976
15. IM Corraliza ML Campo G Soler M Modolell 1994 Determination of arginase activity in macrophages: a micromethod J Immunol Methods 174 231 235 1:CAS:528:DyaK2MXnvFOnuw%3D%3D 10.1016/0022-1759(94)90027-2 8083527 (Pubitemid 24297154)
16. S Zharikov K Krotova H Hu C Baylis RJ Johnson ER Block J Patel 2008 Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells Am J Physiol Cell Physiol 295 C1183 C1190 1:CAS:528:DC%2BD1cXhsVWkurvK 10.1152/ajpcell.00075.2008 18784379 (Pubitemid 352790338)
17. KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2-[Delta][Delta]CT method Methods 25 402 408 1:CAS:528:DC%2BD38XhtFelt7s%3D 10.1006/meth.2001.1262 11846609 (Pubitemid 34164012)
18. JG Vockley CP Jenkinson H Shukla RM Kern WW Grody SD Cederbaum 1996 Cloning and characterization of the human type II arginase gene Genomics 38 118 123 1:CAS:528:DyaK28XnsFajt7g%3D 10.1006/geno.1996.0606 8954792 (Pubitemid 26424589)
19. SM Morris D Bhamidipati D Kepka-Lenhart 1997 Human type II arginase: sequence analysis and tissue-specific expression Gene 193 157 161 1:CAS:528:DyaK2sXks12gtr0%3D 10.1016/S0378-1119(97)00099-1 9256072 (Pubitemid 27294602)
20. F Boess M Kamber S Romer R Gasser D Muller S Albertini L Suter 2003 Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems Toxicol Sci 73 386 402 1:CAS:528:DC%2BD3sXktVCnsr0%3D 10.1093/toxsci/kfg064 12657743 (Pubitemid 36701742)
21. A Chrzanowska M Krawczyk A Baranczyk-Kuzma 2008 Changes in arginase isoenzymes pattern in human hepatocellular carcinoma Biochem Biophys Res Commun 377 337 340 1:CAS:528:DC%2BD1cXhtlykt7zI 10.1016/j.bbrc.2008.09.093 18831962
22. RS Reczkowski DE Ash 1994 Rat liver arginase: kinetic mechanism, alternate substrates, and inhibitors Arch Biochem Biophys 312 31 37 1:CAS:528:DyaK2cXlslekt70%3D 10.1006/abbi.1994.1276 8031143 (Pubitemid 24243795)
23. DM Colleluori SM Morris DE Ash 2001 Expression, purification, and characterization of human type II arginase Arch Biochem Biophys 389 135 143 1:CAS:528:DC%2BD3MXivFalur0%3D 10.1006/abbi.2001.2324 11370664 (Pubitemid 32911551)
24. NJ Kuhn S Ward M Piponski TW Young 1995 Purification of human hepatic arginase and its manganese (II)-dependent and pH-dependent interconversion between active and inactive forms: a possible pH-sensing function of the enzyme on the ornithine cycle Arch Biochem Biophys 320 24 34 1:CAS:528: DyaK2MXmsFChsLs%3D 10.1006/abbi.1995.1338 7793981
25. DM Colleluori DE Ash 2001 Classical and slow-binding inhibitors of human type II arginase Biochemistry 40 9356 9362 1:CAS:528:DC%2BD3MXkvV2qt7s%3D 10.1021/bi010783g 11478904 (Pubitemid 32730058)