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Volumn 17, Issue 3, 2010, Pages 96-101

Pharmacological augmentation strategies in clozapine-resistant schizophrenia: Overcoming the resistance;Estrategias farmacológicas de potenciación en esquizofrenia refractaria a clozapina: Más alla de la resistencia

Author keywords

Amisulpride; Augmentation; Clozapine; Lamotrigine; Resistant schizophrenia; Risperidone; Treatment

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; CLOZAPINE; LAMOTRIGINE; LITHIUM; N METHYL DEXTRO ASPARTIC ACID; RISPERIDONE; VALPROIC ACID;

EID: 77957369070     PISSN: 11345934     EISSN: 15788962     Source Type: Journal    
DOI: 10.1016/j.psiq.2010.07.002     Document Type: Short Survey
Times cited : (6)

References (61)
  • 3
    • 0028029107 scopus 로고
    • Drug treatment of schizophrenia: Myths and realities
    • J. Gerlach, and E. Casey Drug treatment of schizophrenia: Myths and realities Curr Opin Psychiatry 7 1994 65 70
    • (1994) Curr Opin Psychiatry , vol.7 , pp. 65-70
    • Gerlach, J.1    Casey, E.2
  • 4
  • 6
    • 77957367479 scopus 로고    scopus 로고
    • Antipsicticos atpicos: De los modelos animales a los efectos clnicos
    • J. Gerlach, and C. Garca-Ribera Antipsicticos atpicos: de los modelos animales a los efectos clnicos C. Garca-Ribera, Nuevos antipsicticos atpicos 1996 Masson Barcelona 43 65
    • (1996) Nuevos Antipsicticos Atpicos , pp. 43-65
    • Gerlach, J.1    Garca-Ribera, C.2
  • 8
    • 0026780853 scopus 로고
    • Granulocite-macrophage colony stimulating factor (GM-CSF) treatment of clozapine-induced agranulocytosis: A case-report
    • C. Barnas, H. Zwierzina, and M. Hummer Granulocite-macrophage colony stimulating factor (GM-CSF) treatment of clozapine-induced agranulocytosis: a case-report J Clin Psychiatry 53 1992 245 247
    • (1992) J Clin Psychiatry , vol.53 , pp. 245-247
    • Barnas, C.1    Zwierzina, H.2    Hummer, M.3
  • 9
    • 77957341829 scopus 로고    scopus 로고
    • Experiencia en Espaa con los antipsicticos atpicos
    • E. Alvarez Experiencia en Espaa con los antipsicticos atpicos C. Garca-Ribera, Nuevos antipsicticos atpicos 1996 Masson Barcelona 83 101
    • (1996) Nuevos Antipsicticos Atpicos , pp. 83-101
    • Alvarez, E.1
  • 12
    • 0023801345 scopus 로고
    • Clozapine induced agranulocytosis: Non-cross reactivity with other psychotropic drugs
    • J.A. Lieberman, C. Johns, and J.M. Kane Clozapine induced agranulocytosis: non-cross reactivity with other psychotropic drugs J Clin Psychiatry 49 1988 271 277
    • (1988) J Clin Psychiatry , vol.49 , pp. 271-277
    • Lieberman, J.A.1    Johns, C.2    Kane, J.M.3
  • 13
    • 0025175183 scopus 로고
    • HLA-B38, DR4, DQw3 and clozapine-induced agranulocytosis in Jewish patients with schizophrenia
    • J.A. Lieberman, J. Yunis, and E. Egea HLA-B38, DR4, DQw3 and clozapine-induced agranulocytosis in Jewish patients with schizophrenia Arch Gen Psychiatry 47 1990 945 948
    • (1990) Arch Gen Psychiatry , vol.47 , pp. 945-948
    • Lieberman, J.A.1    Yunis, J.2    Egea, E.3
  • 14
    • 68949172254 scopus 로고    scopus 로고
    • 11 year follow-up of mortality in patients with schizophrenia: A population-based cohort study (FIN11 study)
    • J. Tiihonen, J. Lonnqvist, K. Wahlbeck, T. Klaukka, L. Niskanen, and A. Tanskanen 11 year follow-up of mortality in patients with schizophrenia: a population-based cohort study (FIN11 study) Lancet 374 2009 620 627
    • (2009) Lancet , vol.374 , pp. 620-627
    • Tiihonen, J.1    Lonnqvist, J.2    Wahlbeck, K.3    Klaukka, T.4    Niskanen, L.5    Tanskanen, A.6
  • 15
    • 0026796022 scopus 로고
    • Treatment of neuroleptic-nonresponsive schizophrenic patient
    • H.Y. Meltzer Treatment of neuroleptic-nonresponsive schizophrenic patient Schizophr Bull 18 1992 515 542
    • (1992) Schizophr Bull , vol.18 , pp. 515-542
    • Meltzer, H.Y.1
  • 16
    • 0028869668 scopus 로고
    • Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia. Impact on risk-benefits assessment
    • H.Y. Meltzer, and G. Okayli Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia. Impact on risk-benefits assessment Am J Psychiatry 152 1995 183 190
    • (1995) Am J Psychiatry , vol.152 , pp. 183-190
    • Meltzer, H.Y.1    Okayli, G.2
  • 17
    • 0029064332 scopus 로고
    • Patient response and resource management: Another view of clozapine treatment of schizophrenia
    • W.T. Carpenter, R.R. Conley, R.W. Buchanan, A. Breier, and C. Tamminga Patient response and resource management: Another view of clozapine treatment of schizophrenia Am J Psychiatry 152 1995 827 832
    • (1995) Am J Psychiatry , vol.152 , pp. 827-832
    • Carpenter, W.T.1    Conley, R.R.2    Buchanan, R.W.3    Breier, A.4    Tamminga, C.5
  • 18
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic: A double-blind comparison with chlorpromazine/benzotropine
    • J. Kane, G. Honigfeld, and J. Singer Clozapine for the treatment-resistant schizophrenic: a double-blind comparison with chlorpromazine/benzotropine Arch Gen Psychiatry 45 1988 789 796
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3
  • 20
  • 21
    • 0026772116 scopus 로고
    • Clinical and biological response to clozapine in patients with schizophrenia: Crossover comparison with fluphenazine
    • D. Pickard, R.R. Owen, and R.E. Litman Clinical and biological response to clozapine in patients with schizophrenia: crossover comparison with fluphenazine Arch Gen Psychiatry 49 1992 345 353
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 345-353
    • Pickard, D.1    Owen, R.R.2    Litman, R.E.3
  • 22
    • 0023951942 scopus 로고
    • The effect of long term treatment of clozapine in schizophrenia: A retrospective study of 96 patients treated with clozapine for up to 13 years
    • L.H. Lindstrom The effect of long term treatment of clozapine in schizophrenia: a retrospective study of 96 patients treated with clozapine for up to 13 years Acta Psychiatr Scand 77 1988 524 529
    • (1988) Acta Psychiatr Scand , vol.77 , pp. 524-529
    • Lindstrom, L.H.1
  • 23
    • 0024443178 scopus 로고
    • A prospective study of clozapine in treatment-resistant schizophrenic patients, I: Preliminary report
    • H.Y. Meltzer, B. Bastani, and K. Youngkwon A prospective study of clozapine in treatment-resistant schizophrenic patients, I: preliminary report Psychopharmacology (Berl) 99 1989 S68 S72
    • (1989) Psychopharmacology (Berl) , vol.99
    • Meltzer, H.Y.1    Bastani, B.2    Youngkwon, K.3
  • 24
    • 0024428287 scopus 로고
    • Clozapine for refractory schizophrenia: An open study of 14 patients treated up to 2 years
    • J.A. Mattes Clozapine for refractory schizophrenia: an open study of 14 patients treated up to 2 years J Clin Psychiatry 50 1989 389 391
    • (1989) J Clin Psychiatry , vol.50 , pp. 389-391
    • Mattes, J.A.1
  • 25
    • 0024425363 scopus 로고
    • Response to clozapine in chronic psychotic patients
    • R.R. Owen, B.J. Beake, and D. Marby Response to clozapine in chronic psychotic patients Psychopharmacol Bull 25 1989 253 256
    • (1989) Psychopharmacol Bull , vol.25 , pp. 253-256
    • Owen, R.R.1    Beake, B.J.2    Marby, D.3
  • 27
    • 24944500457 scopus 로고    scopus 로고
    • Randomized controlled augmentation trials in clozapine-resistant schizophrenic patients: A critical review
    • V.P. Kontaxakis, P.P. Ferentinos, B.J. Havaki-Kontaxaki, and D.K. Roukas Randomized controlled augmentation trials in clozapine-resistant schizophrenic patients: a critical review Eur Psychiatry 20 2005 409 415
    • (2005) Eur Psychiatry , vol.20 , pp. 409-415
    • Kontaxakis, V.P.1    Ferentinos, P.P.2    Havaki-Kontaxaki, B.J.3    Roukas, D.K.4
  • 28
    • 31344459099 scopus 로고    scopus 로고
    • Augmentation strategies in clozapine-resistant schizophrenia
    • G. Remington, A. Saha, S.A. Chong, and C. Shammi Augmentation strategies in clozapine-resistant schizophrenia CNS Drugs 19 2005 843 872
    • (2005) CNS Drugs , vol.19 , pp. 843-872
    • Remington, G.1    Saha, A.2    Chong, S.A.3    Shammi, C.4
  • 29
    • 33646364823 scopus 로고    scopus 로고
    • Augmentation strategies of clozapine with antipsychotics in the treatment of ultraresistant schizophrenia
    • F. Mouaffac, C. Tranullis, R. Gourevitch, M.F. Poirier, S. Douki, and J.P. Olie Augmentation strategies of clozapine with antipsychotics in the treatment of ultraresistant schizophrenia Clin Neuropharmacol 29 2006 28 33
    • (2006) Clin Neuropharmacol , vol.29 , pp. 28-33
    • Mouaffac, F.1    Tranullis, C.2    Gourevitch, R.3    Poirier, M.F.4    Douki, S.5    Olie, J.P.6
  • 31
    • 0037231694 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of clozapine and relapse a retrospective study of routine clinical data
    • S. Ulrich, B. Baumann, R. Wolf, D. Lehmann, B. Peters, and B. Bogerts Therapeutic drug monitoring of clozapine and relapse a retrospective study of routine clinical data Int J Clin Pharmacol Ther 41 2003 3 13
    • (2003) Int J Clin Pharmacol Ther , vol.41 , pp. 3-13
    • Ulrich, S.1    Baumann, B.2    Wolf, R.3    Lehmann, D.4    Peters, B.5    Bogerts, B.6
  • 32
    • 33646469840 scopus 로고    scopus 로고
    • Serum concentrations of clozapine and norclozapine in the prediction of relapse of patients with schizophrenia
    • Y.Q. Xiang, Z.J. Zhang, Y.Z. Weng, Y.M. Zhai, W.B. Li, and Z.J. Cai Serum concentrations of clozapine and norclozapine in the prediction of relapse of patients with schizophrenia Schizophr Res 83 2006 201 210
    • (2006) Schizophr Res , vol.83 , pp. 201-210
    • Xiang, Y.Q.1    Zhang, Z.J.2    Weng, Y.Z.3    Zhai, Y.M.4    Li, W.B.5    Cai, Z.J.6
  • 33
    • 0037662808 scopus 로고    scopus 로고
    • Serum clozapine levels: A review of their clinical utility
    • C. Greenwood-Smith, D.I. Lubman, and D.J. Castle Serum clozapine levels: a review of their clinical utility J Psychopharmacol 17 2003 234 238
    • (2003) J Psychopharmacol , vol.17 , pp. 234-238
    • Greenwood-Smith, C.1    Lubman, D.I.2    Castle, D.J.3
  • 34
    • 70049104227 scopus 로고    scopus 로고
    • Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia
    • A. Cipriani, M. Boso, and C. Barbui Clozapine combined with different antipsychotic drugs for treatment resistant schizophrenia Cochrane Database Syst Rev 8 2009 CD006324
    • (2009) Cochrane Database Syst Rev , vol.8 , pp. 006324
    • Cipriani, A.1    Boso, M.2    Barbui, C.3
  • 35
    • 0035715712 scopus 로고    scopus 로고
    • Augmentation strategies in the treatment of schizophrenia
    • D.C. Goff, O. Freudenreich, and A.E. Evins Augmentation strategies in the treatment of schizophrenia CNS Spectr 6 2001 907 911
    • (2001) CNS Spectr , vol.6 , pp. 907-911
    • Goff, D.C.1    Freudenreich, O.2    Evins, A.E.3
  • 38
    • 4644247620 scopus 로고    scopus 로고
    • Amisulpride augmentation of clozapine: An open non-randomized study in patients with schizophrenia partially responsive to clozapine
    • J. Munro, P. Matthiasson, S. Osborne, M. Travis, S. Purcell, and A.M. Cobb Amisulpride augmentation of clozapine: an open non-randomized study in patients with schizophrenia partially responsive to clozapine Acta Psychiatr Scand 110 2004 292 298
    • (2004) Acta Psychiatr Scand , vol.110 , pp. 292-298
    • Munro, J.1    Matthiasson, P.2    Osborne, S.3    Travis, M.4    Purcell, S.5    Cobb, A.M.6
  • 39
    • 33645215658 scopus 로고    scopus 로고
    • Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: A randomized, double-blind, placebo-controlled cross-over study
    • A. Kreinin, D. Novitski, and A. Weizman Amisulpride treatment of clozapine-induced hypersalivation in schizophrenia patients: a randomized, double-blind, placebo-controlled cross-over study Int Clin Psychopharmacol 21 2006 99 103
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 99-103
    • Kreinin, A.1    Novitski, D.2    Weizman, A.3
  • 41
    • 34247846196 scopus 로고    scopus 로고
    • Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: A single-blind randomized study
    • Y. Genc, E. Taner, and S. Candansayar Comparison of clozapine-amisulpride and clozapine-quetiapine combinations for patients with schizophrenia who are partially responsive to clozapine: a single-blind randomized study Adv Ther 24 2007 1 13
    • (2007) Adv Ther , vol.24 , pp. 1-13
    • Genc, Y.1    Taner, E.2    Candansayar, S.3
  • 42
    • 46749130922 scopus 로고    scopus 로고
    • Practical Issues with amisulpride in the management of patients with schizophrenia
    • L. Pani, J.M. Villagran, V.P. Kontaxakis, and K. Alptekin Practical Issues with amisulpride in the management of patients with schizophrenia Clin Drug Investig 28 2008 465 477
    • (2008) Clin Drug Investig , vol.28 , pp. 465-477
    • Pani, L.1    Villagran, J.M.2    Kontaxakis, V.P.3    Alptekin, K.4
  • 43
    • 11844304940 scopus 로고    scopus 로고
    • Clozapine augmented with risperidone in the treatment of schizophrenia: A randomized, double-blind, placebo-controlled trial
    • R.C. Josiassen, A. Joseph, E. Kohegyi, S. Stokes, M. Dadvand, and W.W. Paing Clozapine augmented with risperidone in the treatment of schizophrenia: a randomized, double-blind, placebo-controlled trial Am J Psychiatry 162 2005 130 136
    • (2005) Am J Psychiatry , vol.162 , pp. 130-136
    • Josiassen, R.C.1    Joseph, A.2    Kohegyi, E.3    Stokes, S.4    Dadvand, M.5    Paing, W.W.6
  • 45
    • 4344648463 scopus 로고    scopus 로고
    • Ziprasidone-augmentation of clozapine
    • M. Zink, E. Mase, and H. Dressing Ziprasidone-augmentation of clozapine Psychiatr Prax 31 2004 259 261
    • (2004) Psychiatr Prax , vol.31 , pp. 259-261
    • Zink, M.1    Mase, E.2    Dressing, H.3
  • 46
    • 34447570718 scopus 로고    scopus 로고
    • Is clozapine-aripiprazol combination a useful regime in the management of treatment-resistant schizophrenia?
    • K. Karunakaran, T.E. Tungaraza, and G.C. Harborne Is clozapine- aripiprazol combination a useful regime in the management of treatment-resistant schizophrenia? J Psychopharmacol 21 2007 453 456
    • (2007) J Psychopharmacol , vol.21 , pp. 453-456
    • Karunakaran, K.1    Tungaraza, T.E.2    Harborne, G.C.3
  • 47
  • 50
    • 0344979751 scopus 로고    scopus 로고
    • Clozapine plus lamotrigine in treatment-resistant schizophrenia
    • S.M. Dursun, D. McIntosh, and H. Milliken Clozapine plus lamotrigine in treatment-resistant schizophrenia Arch Gen Psychiatry 56 1999 950
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 950
    • Dursun, S.M.1    McIntosh, D.2    Milliken, H.3
  • 51
    • 0035663840 scopus 로고    scopus 로고
    • Augmenting antipsychotic treatment with lamotrigine or topiramate in patients with treatment resistant schizophrenia: A naturalistic case-series outcome study
    • S.M. Dursun, and J.F.W. Deakin Augmenting antipsychotic treatment with lamotrigine or topiramate in patients with treatment resistant schizophrenia: a naturalistic case-series outcome study J Psychopharmacol 15 2001 297 301
    • (2001) J Psychopharmacol , vol.15 , pp. 297-301
    • Dursun, S.M.1    Deakin, J.F.W.2
  • 53
    • 4444352847 scopus 로고    scopus 로고
    • Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia
    • I. Kremer, A. Vass, I. Gorelik, G. Bar, M. Blanaru, and D.C. Javitt Placebo-controlled trial of lamotrigine added to conventional and atypical antipsychotics in schizophrenia Biol Psychiatry 56 2004 441 446
    • (2004) Biol Psychiatry , vol.56 , pp. 441-446
    • Kremer, I.1    Vass, A.2    Gorelik, I.3    Bar, G.4    Blanaru, M.5    Javitt, D.C.6
  • 54
    • 34249323746 scopus 로고    scopus 로고
    • The effect of lamotrigine augmentation in a sample of treatment-resistant schizophrenic patients: A double-blind, placebo-controlled study
    • R. Zoccalli, M.R. Muscatello, A. Bruno, R. Cambria, U. Mic, and E. Spina The effect of lamotrigine augmentation in a sample of treatment-resistant schizophrenic patients: a double-blind, placebo-controlled study Schizophr Res 93 2007 109 116
    • (2007) Schizophr Res , vol.93 , pp. 109-116
    • Zoccalli, R.1    Muscatello, M.R.2    Bruno, A.3    Cambria, R.4    Mic, U.5    Spina, E.6
  • 55
    • 39649116488 scopus 로고    scopus 로고
    • Lamotrigine as add-on therapy in schizophrenia: Results of 2 placebo-controlled trials
    • D.C. Goff, R. Keefe, L. Citrome, K. Davy, J.H. Krystal, and C. Large Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials J Clin Psychopharmacol 27 2007 582 589
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 582-589
    • Goff, D.C.1    Keefe, R.2    Citrome, L.3    Davy, K.4    Krystal, J.H.5    Large, C.6
  • 56
    • 62649086513 scopus 로고    scopus 로고
    • The efficacy of lamotrigine in clozapine-resistant schizophrenia: A systematic review and meta-analysis
    • J. Tiihonen, K. Wahlbeck, and V. Kiviniemi The efficacy of lamotrigine in clozapine-resistant schizophrenia: a systematic review and meta-analysis Schizophr Res 109 2009 10 14
    • (2009) Schizophr Res , vol.109 , pp. 10-14
    • Tiihonen, J.1    Wahlbeck, K.2    Kiviniemi, V.3
  • 57
    • 77953375072 scopus 로고    scopus 로고
    • NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia
    • A.J. Ramsey NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia Prog Brain Res 179 2009 51 58
    • (2009) Prog Brain Res , vol.179 , pp. 51-58
    • Ramsey, A.J.1
  • 58
    • 77953231677 scopus 로고    scopus 로고
    • Expression of the Hippocampal NMDA Receptor GluN1 Subunit and its splicing isoforms in schizophrenia: Post-mortem study
    • M Vrajova, F Stastny, J Horacek, J Lochman, O Sery, and S Pekova Expression of the Hippocampal NMDA Receptor GluN1 Subunit and its splicing isoforms in schizophrenia: post-mortem study Neurochem Res 35 2010 994 1002
    • (2010) Neurochem Res , vol.35 , pp. 994-1002
    • Vrajova, M.1    Stastny, F.2    Horacek, J.3    Lochman, J.4    Sery, O.5    Pekova, S.6
  • 59
    • 77149138329 scopus 로고    scopus 로고
    • Glutamatergic (N-methyl-D-aspartate receptor) hypofrontality in schizophrenia: Too little juice or a miswired brain?
    • G.J. Marek, B. Behl, A.Y. Bespalov, G. Gross, Y. Lee, and H. Schoemaker Glutamatergic (N-methyl-D-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain? Mol Pharmacol 77 2010 317 326
    • (2010) Mol Pharmacol , vol.77 , pp. 317-326
    • Marek, G.J.1    Behl, B.2    Bespalov, A.Y.3    Gross, G.4    Lee, Y.5    Schoemaker, H.6
  • 60
    • 77949447469 scopus 로고    scopus 로고
    • Strategies to Enhance N-Methyl-D-Aspartate Receptor-Mediated Neurotransmission in Schizophrenia: A critical review and meta-analysis
    • GE Tsai, and PY Lin Strategies to Enhance N-Methyl-D-Aspartate Receptor-Mediated Neurotransmission in Schizophrenia: A critical review and meta-analysis Curr Pharm Des 16 2009 522 537
    • (2009) Curr Pharm des , vol.16 , pp. 522-537
    • Tsai, G.E.1    Lin, P.Y.2
  • 61
    • 71049163451 scopus 로고    scopus 로고
    • Glutamate-N-methyl-D-aspartate receptor modulation and minocycline for the treatment of patients with schizophrenia: An update
    • C. Chaves, C.R. Marqu, C. Trzesniak, J.P. Machado de Sousa, A.W. Zuardi, and J.A. Crippa Glutamate-N-methyl-D-aspartate receptor modulation and minocycline for the treatment of patients with schizophrenia: An update Braz J Med Biol Res 42 2009 1002 1014
    • (2009) Braz J Med Biol Res , vol.42 , pp. 1002-1014
    • Chaves, C.1    Marqu, C.R.2    Trzesniak, C.3    MacHado De Sousa, J.P.4    Zuardi, A.W.5    Crippa, J.A.6


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