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Volumn 51, Issue 9, 2010, Pages 4848-4855

VEGF antagonists decrease barrier function of retinal pigment epithelium in vitro: Possible participation of intracellular glutathione

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; BUTHIONINE SULFOXIMINE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GLUCOSE; GLUTATHIONE; PROTEIN ZO1; RANIBIZUMAB; TRIAMCINOLONE ACETONIDE; VASCULOTROPIN; VASCULOTROPIN INHIBITOR; ANGIOGENESIS INHIBITOR; DEXTRAN; DRUG DERIVATIVE; ENZYME INHIBITOR; FLUORESCEIN ISOTHIOCYANATE; MONOCLONAL ANTIBODY; VASCULOTROPIN A;

EID: 77957360007     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4699     Document Type: Article
Times cited : (46)

References (53)
  • 1
    • 38349141652 scopus 로고    scopus 로고
    • Intravitreal bevacizumab in the treatment of neovascular age-related macular degeneration, 6- and 9-month results
    • Cleary CA, Jungkim S, Ravikumar K, Kelliher C, Acheson RW, Hickey-Dwyer M. Intravitreal bevacizumab in the treatment of neovascular age-related macular degeneration, 6- and 9-month results. Eye. 2008;22:82-86.
    • (2008) Eye , vol.22 , pp. 82-86
    • Cleary, C.A.1    Jungkim, S.2    Ravikumar, K.3    Kelliher, C.4    Acheson, R.W.5    Hickey-Dwyer, M.6
  • 2
    • 13944266313 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration
    • Gaudreault J, Fei D, Rusit J, Suboc P, Shiu V. Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration. Invest Ophthalmol Vis Sci. 2005;46:726-733.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 726-733
    • Gaudreault, J.1    Fei, D.2    Rusit, J.3    Suboc, P.4    Shiu, V.5
  • 3
    • 55449084692 scopus 로고    scopus 로고
    • Efficacy and safety of one intravitreal injection of bevacizumab in diabetic macular oedema
    • Fang X, Sakaguchi H, Gomi F, et al. Efficacy and safety of one intravitreal injection of bevacizumab in diabetic macular oedema. Acta Ophthalmol. 2008;86:800-805.
    • (2008) Acta Ophthalmol , vol.86 , pp. 800-805
    • Fang, X.1    Sakaguchi, H.2    Gomi, F.3
  • 4
    • 67349141386 scopus 로고    scopus 로고
    • Intravitreal bevacizumab for diabetic macular edema associated with severe capillary loss: One-year results of a pilot study
    • Bonini-Filho M, Costa RA, Calucci D, Jorge R, Melo LA Jr, Scott IU. Intravitreal bevacizumab for diabetic macular edema associated with severe capillary loss: one-year results of a pilot study. Am J Ophthalmol. 2009;147:1022-1030.
    • (2009) Am J Ophthalmol , vol.147 , pp. 1022-1030
    • Bonini-Filho, M.1    Costa, R.A.2    Calucci, D.3    Jorge, R.4    Melo Jr., L.A.5    Scott, I.U.6
  • 5
    • 77953404644 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin) in the treatment of macular edema secondary to retinal vein occlusion
    • Gutie ́rrez JC, Barquet LA, Caminal JM, et al. Intravitreal bevacizumab (Avastin) in the treatment of macular edema secondary to retinal vein occlusion. Clin Ophthalmol. 2008;2:787-791.
    • (2008) Clin Ophthalmol , vol.2 , pp. 787-791
    • Gutiérrez, J.C.1    Barquet, L.A.2    Caminal, J.M.3
  • 6
    • 68249096210 scopus 로고    scopus 로고
    • Safety and efficacy of intravitreal bevacizumab (Avastin) for the management of branch and hemiretinal vein occlusion
    • Gregori NZ, Rattan GH, Rosenfeld PJ, et al. Safety and efficacy of intravitreal bevacizumab (Avastin) for the management of branch and hemiretinal vein occlusion. Retina. 2009;29:913-925.
    • (2009) Retina , vol.29 , pp. 913-925
    • Gregori, N.Z.1    Rattan, G.H.2    Rosenfeld, P.J.3
  • 7
    • 71449106064 scopus 로고    scopus 로고
    • Long-term follow-up of OCT-guided bevacizumab treatment of macular edema due to retinal vein occlusion
    • Hoeh AE, Ach T, Schaal KB, Scheuerle AF, Dithmar S. Long-term follow-up of OCT-guided bevacizumab treatment of macular edema due to retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol. 2009;247:1635-1641.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 1635-1641
    • Hoeh, A.E.1    Ach, T.2    Schaal, K.B.3    Scheuerle, A.F.4    Dithmar, S.5
  • 8
    • 70350149839 scopus 로고    scopus 로고
    • Intravitreal injection of bevacizumab for macular edema secondary to branch retinal vein occlusion: Results after 12 months and multiple regression analysis
    • Kondo M, Kondo N, Ito Y, et al. Intravitreal injection of bevacizumab for macular edema secondary to branch retinal vein occlusion: results after 12 months and multiple regression analysis. Retina. 2009;29:1242-1248.
    • (2009) Retina , vol.29 , pp. 1242-1248
    • Kondo, M.1    Kondo, N.2    Ito, Y.3
  • 9
    • 63549146725 scopus 로고    scopus 로고
    • Repeated intravitreal injection of bevacizumab for clinically significant diabetic macular edema
    • Roh MI, Byeon SH, Kwon OW. Repeated intravitreal injection of bevacizumab for clinically significant diabetic macular edema. Retina. 2008;28:1314-1318.
    • (2008) Retina , vol.28 , pp. 1314-1318
    • Roh, M.I.1    Byeon, S.H.2    Kwon, O.W.3
  • 10
    • 39349095670 scopus 로고    scopus 로고
    • Retinal pigment epithelial tears after intravitreal bevacizumab injection for predominantly classic choroidal neovascularization
    • Arias L, Caminal JM, Rubio M, Pujol O, Arruga J. Retinal pigment epithelial tears after intravitreal bevacizumab injection for predominantly classic choroidal neovascularization. Eur J Ophthalmol. 2007;17:992-995.
    • (2007) Eur J Ophthalmol , vol.17 , pp. 992-995
    • Arias, L.1    Caminal, J.M.2    Rubio, M.3    Pujol, O.4    Arruga, J.5
  • 11
    • 33847025263 scopus 로고    scopus 로고
    • Retinal pigment epithelial tear after intravitreal ranibizumab
    • Bakri SJ, Kitzmann AS. Retinal pigment epithelial tear after intravitreal ranibizumab. Am J Ophthalmol. 2007;143:505-507.
    • (2007) Am J Ophthalmol , vol.143 , pp. 505-507
    • Bakri, S.J.1    Kitzmann, A.S.2
  • 12
    • 33847030713 scopus 로고    scopus 로고
    • Retinal pigment epithelium tears following ranibizumab for exudative age-related macular degeneration
    • Carvounis PE, Kopel AC, Benz MS. Retinal pigment epithelium tears following ranibizumab for exudative age-related macular degeneration. Am J Ophthalmol. 2007;143:504-505.
    • (2007) Am J Ophthalmol , vol.143 , pp. 504-505
    • Carvounis, P.E.1    Kopel, A.C.2    Benz, M.S.3
  • 13
    • 38449095942 scopus 로고    scopus 로고
    • Retinal pigment epithelial tear after ranibizumab therapy for subfoveal fibrovascular pigment epithelial detachment
    • Chan CK, Lin SG. Retinal pigment epithelial tear after ranibizumab therapy for subfoveal fibrovascular pigment epithelial detachment. Eur J Ophthalmol. 2007;17:674-676.
    • (2007) Eur J Ophthalmol , vol.17 , pp. 674-676
    • Chan, C.K.1    Lin, S.G.2
  • 14
    • 34250176573 scopus 로고    scopus 로고
    • Retinal pigment epithelium tears after intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration
    • Ronan SM, Yoganathan P, Chien FY, et al. Retinal pigment epithelium tears after intravitreal injection of bevacizumab (Avastin) for neovascular age-related macular degeneration. Retina. 2007;27: 535-540.
    • (2007) Retina , vol.27 , pp. 535-540
    • Ronan, S.M.1    Yoganathan, P.2    Chien, F.Y.3
  • 15
    • 62549090117 scopus 로고    scopus 로고
    • Retinal pigment epithelial tears after single administration of intravitreal bevacizumab for neovascular age-related macular degeneration
    • Gelisken F, Ziemssen F, Voelker M, Bartz-Schmidt KU, Inhoffen W. Retinal pigment epithelial tears after single administration of intravitreal bevacizumab for neovascular age-related macular degeneration. Eye. 2009;23:694-702.
    • (2009) Eye , vol.23 , pp. 694-702
    • Gelisken, F.1    Ziemssen, F.2    Voelker, M.3    Bartz-Schmidt, K.U.4    Inhoffen, W.5
  • 16
    • 67649171066 scopus 로고    scopus 로고
    • Predictors of anti-VEGF associated retinal pigment epithelial tear using FA and OCT analysis
    • Chiang A, Chang LK, Yu F, Sarraf D. Predictors of anti-VEGF associated retinal pigment epithelial tear using FA and OCT analysis. Retina. 2008;28:1265-1269.
    • (2008) Retina , vol.28 , pp. 1265-1269
    • Chiang, A.1    Chang, L.K.2    Yu, F.3    Sarraf, D.4
  • 17
    • 78349235444 scopus 로고    scopus 로고
    • Retinal pigment epithelium tears after intravitreal injection of ranibizumab for predominantly classic neovascular membranes secondary to age-related macular degeneration
    • In press
    • Konstantinidis L, Ambresin A, Zografos L, Mantel I. Retinal pigment epithelium tears after intravitreal injection of ranibizumab for predominantly classic neovascular membranes secondary to age-related macular degeneration. Acta Ophthalmol. In press.
    • Acta Ophthalmol
    • Konstantinidis, L.1    Ambresin, A.2    Zografos, L.3    Mantel, I.4
  • 18
    • 34250181354 scopus 로고    scopus 로고
    • Retinal pigment epithelial tears after intravitreal bevacizumab injection for neovascular agerelated macular degeneration
    • Chan CK, Meyer CH, Gross JG, et al. Retinal pigment epithelial tears after intravitreal bevacizumab injection for neovascular agerelated macular degeneration. Retina. 2007;27:541-551.
    • (2007) Retina , vol.27 , pp. 541-551
    • Chan, C.K.1    Meyer, C.H.2    Gross, J.G.3
  • 19
    • 47649105848 scopus 로고    scopus 로고
    • Acute anterior non-granulomatous uveitis after intravitreal injection of bevacizumab
    • Hasler S, Schmid MK, Becht CN. Acute anterior non-granulomatous uveitis after intravitreal injection of bevacizumab. Klin Monatsbl Augenheilkd. 2008;225:446-447.
    • (2008) Klin Monatsbl Augenheilkd , vol.225 , pp. 446-447
    • Hasler, S.1    Schmid, M.K.2    Becht, C.N.3
  • 20
    • 54949136462 scopus 로고    scopus 로고
    • Acute intraocular inflammation after intravitreous injections of bevacizumab for treatment of neovascular age-related macular degeneration
    • Wickremasinghe SS, Michalova K, Gilhotra J, et al. Acute intraocular inflammation after intravitreous injections of bevacizumab for treatment of neovascular age-related macular degeneration. Ophthalmology. 2008;115:1911-1915.
    • (2008) Ophthalmology , vol.115 , pp. 1911-1915
    • Wickremasinghe, S.S.1    Michalova, K.2    Gilhotra, J.3
  • 21
    • 47649125703 scopus 로고    scopus 로고
    • Complications in patients after intravitreal injection of bevacizumab
    • Shima C, Sakaguchi H, Gomi F, et al. Complications in patients after intravitreal injection of bevacizumab. Acta Ophthalmol. 2008;86:372-376.
    • (2008) Acta Ophthalmol , vol.86 , pp. 372-376
    • Shima, C.1    Sakaguchi, H.2    Gomi, F.3
  • 22
    • 67749116153 scopus 로고    scopus 로고
    • Bevacizumab is not toxic to retinal ganglion cells after repeated intravitreal injection
    • Cheng CK, Peng PH, Tien LT, Cai YJ, Chen CF, Lee YJ. Bevacizumab is not toxic to retinal ganglion cells after repeated intravitreal injection. Retina. 2009;29:306-312.
    • (2009) Retina , vol.29 , pp. 306-312
    • Cheng, C.K.1    Peng, P.H.2    Tien, L.T.3    Cai, Y.J.4    Chen, C.F.5    Lee, Y.J.6
  • 23
    • 38049160197 scopus 로고    scopus 로고
    • Bevacizumab (Avastin) does not harm retinal function after intravitreal injection as shown by electroretinography in adult mice
    • Heiduschka P, Julien S, Hofmeister S, Bartz-Schmidt KU, Schraermeyer U. Bevacizumab (Avastin) does not harm retinal function after intravitreal injection as shown by electroretinography in adult mice. Retina. 2008;28:46-55.
    • (2008) Retina , vol.28 , pp. 46-55
    • Heiduschka, P.1    Julien, S.2    Hofmeister, S.3    Bartz-Schmidt, K.U.4    Schraermeyer, U.5
  • 24
    • 69449100517 scopus 로고    scopus 로고
    • In vitro evaluation of bevacizumab toxicity on a retinal ganglion cell line
    • Sharma RK, Chalam KV. In vitro evaluation of bevacizumab toxicity on a retinal ganglion cell line. Acta Ophthalmol. 2009;87:618-622.
    • (2009) Acta Ophthalmol , vol.87 , pp. 618-622
    • Sharma, R.K.1    Chalam, K.V.2
  • 28
    • 64449085160 scopus 로고    scopus 로고
    • Triamcinolone acetonide prevents oxidative stress-induced tight junction disruption of retinal pigment epithelial cells
    • Miura Y, Roider J. Triamcinolone acetonide prevents oxidative stress-induced tight junction disruption of retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol. 2009;247:641-649.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , pp. 641-649
    • Miura, Y.1    Roider, J.2
  • 29
    • 0029778264 scopus 로고    scopus 로고
    • The involvement of polyamines in the proliferation of cultured retinal pigment epithelial cells
    • Yanagihara N, Moriwaki M, Shiraki K, Miki T, Otani S. The involvement of polyamines in the proliferation of cultured retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1996;37:1975-1983.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1975-1983
    • Yanagihara, N.1    Moriwaki, M.2    Shiraki, K.3    Miki, T.4    Otani, S.5
  • 31
    • 16244370730 scopus 로고    scopus 로고
    • Vascular endothelial growth factor reduced and connective tissue growth factor induced by triamcinolone in ARPE19 cells under oxidative stress
    • Matsuda S, Gomi F, Oshima Y, Tohyama M, Tano Y. Vascular endothelial growth factor reduced and connective tissue growth factor induced by triamcinolone in ARPE19 cells under oxidative stress. Invest Ophthalmol Vis Sci. 2005;46:1062-1068.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1062-1068
    • Matsuda, S.1    Gomi, F.2    Oshima, Y.3    Tohyama, M.4    Tano, Y.5
  • 32
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)
    • Griffith OW, Meister A. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem. 1979;254:7558-7560.
    • (1979) J Biol Chem , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 34
    • 0021844870 scopus 로고
    • Retinal pigment epithelial detachments in the elderly: Classification and outcome
    • Casswell AG, Kohen D, Bird AC. Retinal pigment epithelial detachments in the elderly: classification and outcome. Br J Ophthalmol. 1985;69:397-403.
    • (1985) Br J Ophthalmol , vol.69 , pp. 397-403
    • Casswell, A.G.1    Kohen, D.2    Bird, A.C.3
  • 35
    • 0036951480 scopus 로고    scopus 로고
    • Pigment epithelial detachment in the elderly: Clinical differentiation, natural course and pathogenetic implications
    • Pauleikhoff D, Löffert D, Spital G, et al. Pigment epithelial detachment in the elderly: clinical differentiation, natural course and pathogenetic implications. Graefes Arch Clin Exp Ophthalmol. 2002;240:533-538
    • (2002) Graefes Arch Clin Exp Ophthalmol , vol.240 , pp. 533-538
    • Pauleikhoff, D.1    Löffert, D.2    Spital, G.3
  • 36
    • 34547456557 scopus 로고    scopus 로고
    • Age-associated perturbations in glutathione synthesis in mouse liver
    • Toroser D, Sohal RS. Age-associated perturbations in glutathione synthesis in mouse liver. Biochem J. 2007;405:583-589.
    • (2007) Biochem J , vol.405 , pp. 583-589
    • Toroser, D.1    Sohal, R.S.2
  • 37
    • 0030047789 scopus 로고    scopus 로고
    • Effect of age on alteration of glutathione metabolism following chronic cigarette smoke inhalation in mice
    • Teramoto S, Uejima Y, Teramoto K, Ouchi Y, Fukuchi Y. Effect of age on alteration of glutathione metabolism following chronic cigarette smoke inhalation in mice. Lung. 1996;174:119-126.
    • (1996) Lung , vol.174 , pp. 119-126
    • Teramoto, S.1    Uejima, Y.2    Teramoto, K.3    Ouchi, Y.4    Fukuchi, Y.5
  • 40
    • 0029819075 scopus 로고    scopus 로고
    • Platelets attenuate oxidant-induced permeability in endothelial monolayers: Glutathione- dependent mechanisms
    • Strange C, Gottehrer A, Birmingham K, Heffner JE. Platelets attenuate oxidant-induced permeability in endothelial monolayers: glutathione- dependent mechanisms. J Appl Physiol. 1996;81:1701-1706.
    • (1996) J Appl Physiol , vol.81 , pp. 1701-1706
    • Strange, C.1    Gottehrer, A.2    Birmingham, K.3    Heffner, J.E.4
  • 42
    • 77449104200 scopus 로고    scopus 로고
    • Vascular endothelial growth factor as an autocrine survival factor for retinal pigment epithelial cells under oxidative stress via the VEGF-R2/PI3K/Akt
    • Byeon SH, Lee SC, Choi SH, et al. Vascular endothelial growth factor as an autocrine survival factor for retinal pigment epithelial cells under oxidative stress via the VEGF-R2/PI3K/Akt. Invest Ophthalmol Vis Sci. 2010;51:1190-1197.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 1190-1197
    • Byeon, S.H.1    Lee, S.C.2    Choi, S.H.3
  • 43
    • 0021111648 scopus 로고
    • Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
    • Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science. 1983;219:983-985.
    • (1983) Science , vol.219 , pp. 983-985
    • Senger, D.R.1    Galli, S.J.2    Dvorak, A.M.3    Perruzzi, C.A.4    Harvey, V.S.5    Dvorak, H.F.6
  • 44
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989;246:1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 45
    • 36448935689 scopus 로고    scopus 로고
    • VEGF modulation of retinal pigment epithelium resistance
    • Ablonczy Z, Crosson CE. VEGF modulation of retinal pigment epithelium resistance. Exp Eye Res. 2007;85:762-771.
    • (2007) Exp Eye Res , vol.85 , pp. 762-771
    • Ablonczy, Z.1    Crosson, C.E.2
  • 46
    • 27944461483 scopus 로고    scopus 로고
    • VEGF differentially regulates transcription and translation of ZO-1alpha+ and ZO-1alpha- and mediates trans-epithelial resistance in cultured endothelial and epithelial cells
    • Ghassemifar R, Lai CM, Rakoczy PE. VEGF differentially regulates transcription and translation of ZO-1alpha+ and ZO-1alpha- and mediates trans-epithelial resistance in cultured endothelial and epithelial cells. Cell Tissue Res. 2006;323:117-125.
    • (2006) Cell Tissue Res , vol.323 , pp. 117-125
    • Ghassemifar, R.1    Lai, C.M.2    Rakoczy, P.E.3
  • 47
    • 53449095951 scopus 로고    scopus 로고
    • Comparison of bevacizumab, ranibizumab and pegaptanib in vitro: Efficiency and possible additional pathways
    • Klettner A, Roider J. Comparison of bevacizumab, ranibizumab and pegaptanib in vitro: efficiency and possible additional pathways. Invest Ophthalmol Vis Sci. 2008;49:4523-4527.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4523-4527
    • Klettner, A.1    Roider, J.2
  • 48
    • 36349031109 scopus 로고    scopus 로고
    • Combination therapy for choroidal neovascularization
    • Augustin AJ, Offermann I. Combination therapy for choroidal neovascularization. Drugs Aging. 2007;24:979-990.
    • (2007) Drugs Aging , vol.24 , pp. 979-990
    • Augustin, A.J.1    Offermann, I.2
  • 49
    • 58149374861 scopus 로고    scopus 로고
    • Intravitreal bevacizumab versus combined bevacizumab-triamcionlone versus macular laser photocoagulation in diabetic macular edema
    • Faghihi H, Roohipoor R, Mohammadi SF, et al. Intravitreal bevacizumab versus combined bevacizumab-triamcionlone versus macular laser photocoagulation in diabetic macular edema. Eur J Ophthalmol. 2008;18:941-948.
    • (2008) Eur J Ophthalmol , vol.18 , pp. 941-948
    • Faghihi, H.1    Roohipoor, R.2    Mohammadi, S.F.3
  • 50
    • 63149165854 scopus 로고    scopus 로고
    • Verteporfin photodynamic therapycombined with intravitreal bevacizumab for neovascular age-related macular degeneration
    • Kaiser PK, Boyer DS, Garcia R, et al. Verteporfin photodynamic therapycombined with intravitreal bevacizumab for neovascular age-related macular degeneration. Ophthalmology. 2009;116:747-755.
    • (2009) Ophthalmology , vol.116 , pp. 747-755
    • Kaiser, P.K.1    Boyer, D.S.2    Garcia, R.3
  • 51
    • 80052097801 scopus 로고    scopus 로고
    • Effects of combination therapy with verteporfin photodynamic therapy and ranibizumab in patients with age-related macular degeneration
    • In press
    • Wolf-Schnurrbusch UE, Brinkmann CK, Berger L, Wolf S. Effects of combination therapy with verteporfin photodynamic therapy and ranibizumab in patients with age-related macular degeneration. Acta Ophthalmologica. In press.
    • Acta Ophthalmologica
    • Wolf-Schnurrbusch, U.E.1    Brinkmann, C.K.2    Berger, L.3    Wolf, S.4
  • 52
    • 68049148382 scopus 로고    scopus 로고
    • Rationale for combination therapy in age-related macular degeneration
    • Spaid RF. Rationale for combination therapy in age-related macular degeneration. Retina. 2009;29:S5-S7.
    • (2009) Retina , vol.29
    • Spaid, R.F.1
  • 53
    • 68049135739 scopus 로고    scopus 로고
    • Combination therapy for age-related macular degeneration
    • Patel S. Combination therapy for age-related macular degeneration. Retina. 2009;29:S45-S48.
    • (2009) Retina , vol.29
    • Patel, S.1


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