-
1
-
-
33745094315
-
Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid
-
Argyrou, A., M. Vetting, B. Aladegbami, and J. Blanchard. 2006. Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid. Nat. Struct. Mol. Biol. 13:408-413.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 408-413
-
-
Argyrou, A.1
Vetting, M.2
Aladegbami, B.3
Blanchard, J.4
-
2
-
-
0034613029
-
Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: New insight into the enzymatic mechanism and sulfa-drug action
-
Baca, A., R. Sirawaraporn, S. Turley, W. Sirawaraporn, and W. Hol. 2000. Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action. J. Mol. Biol. 302:1193-1212.
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 1193-1212
-
-
Baca, A.1
Sirawaraporn, R.2
Turley, S.3
Sirawaraporn, W.4
Hol, W.5
-
3
-
-
34249654136
-
Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus
-
Besier, S., A. Ludwig, K. Ohlsen, V. Brade, and T. Wichelhaus. 2007. Molecular analysis of the thymidine-auxotrophic small colony variant phenotype of Staphylococcus aureus. Int. J. Med. Microbiol. 297:217-225.
-
(2007)
Int. J. Med. Microbiol.
, vol.297
, pp. 217-225
-
-
Besier, S.1
Ludwig, A.2
Ohlsen, K.3
Brade, V.4
Wichelhaus, T.5
-
4
-
-
44449104965
-
The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates
-
Besier, S., J. Zander, B. C. Kahl, P. Kraiczy, V. Brade, and T. A. Wichelhaus. 2008. The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. Antimicrob. Agents Chemother. 52:2183-2189.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 2183-2189
-
-
Besier, S.1
Zander, J.2
Kahl, B.C.3
Kraiczy, P.4
Brade, V.5
Wichelhaus, T.A.6
-
5
-
-
38649119459
-
Mutations of thymidylate synthase (encoded by thyA) are responsible for thymidine dependency in clinical small-colony variants of Staphylococcus aureus
-
Chatterjee, I., A. Kriegeskorte, A. Fischer, S. Deiwick, N. Theimann, R. Proctor, G. Peters, M. Herrmann, and B. Kahl. 2008. In vivo mutations of thymidylate synthase (encoded by thyA) are responsible for thymidine dependency in clinical small-colony variants of Staphylococcus aureus. J. Bacteriol. 190:834-842.
-
(2008)
J. Bacteriol.
, vol.190
, pp. 834-842
-
-
Chatterjee, I.1
Kriegeskorte, A.2
Fischer, A.3
Deiwick, S.4
Theimann, N.5
Proctor, R.6
Peters, G.7
Herrmann, M.8
Kahl, B.9
-
6
-
-
70350334133
-
Tuberculosis and trimethoprim-sulfamethoxazole
-
Forgacs, P., N. Wengenack, L. Hall, S. Zimmerman, M. Silverman, and G. Roberts. 2009. Tuberculosis and trimethoprim-sulfamethoxazole. Antimicrob. Agents Chemother. 53:4789-4793.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 4789-4793
-
-
Forgacs, P.1
Wengenack, N.2
Hall, L.3
Zimmerman, S.4
Silverman, M.5
Roberts, G.6
-
7
-
-
50949123930
-
Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis
-
Gengenbacher, M., T. Xu, P. Niyomrattanakit, G. Spraggon, and T. Dick. 2008. Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis. FEMS Microbiol. Lett. 287:128-135.
-
(2008)
FEMS Microbiol. Lett.
, vol.287
, pp. 128-135
-
-
Gengenbacher, M.1
Xu, T.2
Niyomrattanakit, P.3
Spraggon, G.4
Dick, T.5
-
8
-
-
70349138844
-
Contribution of dfrA and inhA mutations to the detection of isoniazid-resistant Mycobacterium tuberculosis isolates
-
Ho, Y., Y. Sun, S. Wong, and A. Lee. 2009. Contribution of dfrA and inhA mutations to the detection of isoniazid-resistant Mycobacterium tuberculosis isolates. Antimicrob. Agents Chemother. 53:4010-4012.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 4010-4012
-
-
Ho, Y.1
Sun, Y.2
Wong, S.3
Lee, A.4
-
9
-
-
0035370341
-
Resistance to trimethoprim-sulfamethoxazole
-
Huovinen, P. 2001. Resistance to trimethoprim-sulfamethoxazole. Clin. Infect. Dis. 32:1608-1614.
-
(2001)
Clin. Infect. Dis.
, vol.32
, pp. 1608-1614
-
-
Huovinen, P.1
-
10
-
-
0028854358
-
Tri-methoprim and sulfonamide resistance
-
Huovinen, P., L. Sundström, G. Swedberg, and O. Sköld. 1995. Tri-methoprim and sulfonamide resistance. Antimicrob. Agents Chemother. 39:279-289.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 279-289
-
-
Huovinen, P.1
Sundström, L.2
Swedberg, G.3
Sköld, O.4
-
11
-
-
0034645774
-
Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs
-
Li, R., R. Sirawaraporn, P. Chitnumsub, W. Sirawaraporn, J. Wooden, F. Athappilly, S. Turley, and W. G. J. Hol. 2000. Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs. J. Mol. Biol. 295:307-323.
-
(2000)
J. Mol. Biol.
, vol.295
, pp. 307-323
-
-
Li, R.1
Sirawaraporn, R.2
Chitnumsub, P.3
Sirawaraporn, W.4
Wooden, J.5
Athappilly, F.6
Turley, S.7
Hol, W.G.J.8
-
12
-
-
66149143506
-
Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis
-
Mathys, V., R. Wintjens, P. Lefevre, J. Bertout, A. Singhal, M. Kiass, N. Kurepina, X. Wang, B. Mathema, A. Baulard, B. Kreiswirth, and P. Bifani. 2009. Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 53:2100-2109.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2100-2109
-
-
Mathys, V.1
Wintjens, R.2
Lefevre, P.3
Bertout, J.4
Singhal, A.5
Kiass, M.6
Kurepina, N.7
Wang, X.8
Mathema, B.9
Baulard, A.10
Kreiswirth, B.11
Bifani, P.12
-
13
-
-
3142583521
-
The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria
-
Rengarajan, J., C. M. Sassetti, V. Naroditskaya, A. Sloutsky, B. R. Bloom, and E. J. Rubin. 2004. The folate pathway is a target for resistance to the drug para-aminosalicylic acid (PAS) in mycobacteria. Mol. Microbiol. 53:275-282.
-
(2004)
Mol. Microbiol.
, vol.53
, pp. 275-282
-
-
Rengarajan, J.1
Sassetti, C.M.2
Naroditskaya, V.3
Sloutsky, A.4
Bloom, B.R.5
Rubin, E.J.6
-
14
-
-
60349114577
-
Staphylococcus aureus as an intracellular pathogen: The role of small colony variants
-
Sendi, P., and R. Proctor. 2009. Staphylococcus aureus as an intracellular pathogen: the role of small colony variants. Trends Microbiol. 17:54-58.
-
(2009)
Trends Microbiol.
, vol.17
, pp. 54-58
-
-
Sendi, P.1
Proctor, R.2
-
15
-
-
0032444693
-
Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase
-
Suling, W., R. Reynolds, E. Barrow, L. Wilson, J. Piper, and W. Barrow. 1998. Susceptibilities of Mycobacterium tuberculosis and Mycobacterium avium complex to lipophilic deazapteridine derivatives, inhibitors of dihydrofolate reductase. J. Antimicrob. Chemother. 42:811-815.
-
(1998)
J. Antimicrob. Chemother.
, vol.42
, pp. 811-815
-
-
Suling, W.1
Reynolds, R.2
Barrow, E.3
Wilson, L.4
Piper, J.5
Barrow, W.6
-
16
-
-
65749109291
-
Analysis of mutational resistance to trimethoprim in Staphylococcus aureus by genetic and structural modelling techniques
-
Vickers, A., N. Potter, C. Fishwick, I. Chopra, and A. O'Neill. 2009. Analysis of mutational resistance to trimethoprim in Staphylococcus aureus by genetic and structural modelling techniques. J. Antimicrob. Chemother. 63:1112-1117.
-
(2009)
J. Antimicrob. Chemother.
, vol.63
, pp. 1112-1117
-
-
Vickers, A.1
Potter, N.2
Fishwick, C.3
Chopra, I.4
O'Neill, A.5
-
17
-
-
35848935866
-
The mechanism of isoniazid killing: Clarity through the scope of genetics
-
Vilchèze, C., and W. J. Jacobs. 2007. The mechanism of isoniazid killing: clarity through the scope of genetics. Annu. Rev. Microbiol. 61:35-50.
-
(2007)
Annu. Rev. Microbiol.
, vol.61
, pp. 35-50
-
-
Vilchèze, C.1
Jacobs, W.J.2
-
18
-
-
70350329241
-
Reconsidering some approved antimicrobial agents for tuberculosis
-
Young, L. 2009. Reconsidering some approved antimicrobial agents for tuberculosis. Antimicrob. Agents Chemother. 53:4577-4579.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 4577-4579
-
-
Young, L.1
-
19
-
-
0242501573
-
Insights into antifolate resistance from malarial DHFR-TS structures
-
Yuvaniyama, J., P. Chitnumsub, S. Kamchonwongpaisan, J. Vanichtanankul, W. Sirawaraporn, P. Taylor, M. Walkinshaw, and Y. Yuthavong. 2003. Insights into antifolate resistance from malarial DHFR-TS structures. Nat. Struct. Biol. 10:357-365.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 357-365
-
-
Yuvaniyama, J.1
Chitnumsub, P.2
Kamchonwongpaisan, S.3
Vanichtanankul, J.4
Sirawaraporn, W.5
Taylor, P.6
Walkinshaw, M.7
Yuthavong, Y.8
-
20
-
-
77955865485
-
Mutations in the thymidylate synthase gene is a major mechanism in the para-aminosalicylic acid resistance of M. tuberculosis
-
In Chinese
-
Zhang, Z., Y. Zhao, Z. Li, H. Jia, Y. Liu, X. Chen, Z. Liu, B. Du, A. Xing, and Y. Ma. 2007. Mutations in the thymidylate synthase gene is a major mechanism in the para-aminosalicylic acid resistance of M. tuberculosis. Zhonghua Jie He He Hu Xi Za Zhi 30:683-685. (In Chinese.)
-
(2007)
Zhonghua Jie He He Hu Xi Za Zhi
, vol.30
, pp. 683-685
-
-
Zhang, Z.1
Zhao, Y.2
Li, Z.3
Jia, H.4
Liu, Y.5
Chen, X.6
Liu, Z.7
Du, B.8
Xing, A.9
Ma, Y.10
|