A combined A431 cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening compounds from total alkaloid of Radix Caulophylli acting on the human EGFR

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 28, 2010, Pages 2712-2718

  Sun, Meng ^a,b   Ren, Jing ^a,b   Du, Hui ^a,b   Zhang, Yanmin ^a,b   Zhang, Jie ^a,b   Wang, Sicen ^a,b   He, Langchong ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Cell membrane chromatography (CMC); EGFR; High performance liquid chromatography mass spectrometry (LC MS); Radix caulophylli

Indexed keywords

ACTIVE COMPONENTS; ACTIVE MOLECULES; ANALYTICAL METHOD; CELL MEMBRANE CHROMATOGRAPHIES; DRUG DISCOVERY; EGFR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY/MASS SPECTROMETRIES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY (LC/MS); MEDICINAL HERB; RADIX CAULOPHYLLI; SCREENING COMPOUNDS; SORAFENIB; TRADITIONAL CHINESE MEDICINE;

CELL MEMBRANES; CYTOLOGY; ELECTRIC SWITCHGEAR; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; MEDICINE;

CHROMATOGRAPHY;

ALKALOID; CAULOPHINE; EPIDERMAL GROWTH FACTOR RECEPTOR; NITRENDIPINE; SORAFENIB; TAMSULOSIN; TASPINE; UNCLASSIFIED DRUG;

A431 CELL LINE; ARTICLE; CANCER CELL CULTURE; CELL FRACTIONATION; CELL GROWTH; CELL MEMBRANE; CELL MEMBRANE CHROMATOGRAPHY; CELL VIABILITY; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; HERB; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR DOCKING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RADIX CAULOPHYLLI;

ALKALOIDS; CAULOPHYLLUM; CELL LINE, TUMOR; CELL MEMBRANE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; FLUORENES; HUMANS; HYDROGEN BONDING; MASS SPECTROMETRY; PLANT ROOTS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 77957314101     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2010.08.010     Document Type: Article

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