Ventilator-associated lung injury superposed to oleic acid infusion or surfactant depletion: Histopathological characteristics of two porcine models of acute lung injury

European Surgical Research

Volumn 45, Issue 3-4, 2010, Pages 121-133

  Wang, H M ^a,b   Bodenstein, M ^a   Duenges, B ^a   Ganatti, S ^a   Boehme, S ^a   Ning, Y ^a   Roehrig, B ^a   Markstaller, K ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

Author keywords

Histopathology; Lavage model; Lung, respiratory distress syndrome; Model, pig; Oleic acid injection model

Indexed keywords

OLEIC ACID; PROTEIN; SURFACTANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATELECTASIS; BLOOD GAS ANALYSIS; CONTROLLED STUDY; FEMALE; GAS EXCHANGE; HISTOPATHOLOGY; LUNG BAROTRAUMA; LUNG EDEMA; LUNG HEMODYNAMICS; LUNG LAVAGE; LUNG WEIGHT; MALE; NECROSIS; NONHUMAN; PRESSURE SUPPORT VENTILATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; SCORING SYSTEM; SPIROMETRY; SWINE; VENTILATOR INDUCED LUNG INJURY;

ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; OLEIC ACID; PULMONARY SURFACTANTS; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; SWINE; THERAPEUTIC IRRIGATION;

EID: 77957297171     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000318599     Document Type: Article

References (26)

1. Karmrodt J, Bletz C, Yuan S, David M, Heussel CP, Markstaller K: Quantification of atelectatic lung volumes in two different porcine models of ARDS. Br J Anaesth 2006; 97: 883-895.
2. Broccard A, Shapiro RS, Schmitz LL, Adams AB, Nahum A, Marini JJ: Prone positioning attenuates and redistributes ventilator-induced lung injury in dogs. Crit Care Med 2000; 28: 295-303.
3. Doctor A, Mazzoni MC, DelBalzo U, DiCanzio J, Arnold JH: High-frequency oscillatory ventilation of the perfluorocarbon-filled lung: preliminary results in an animal model of acute lung injury. Crit Care Med 1999; 27: 2500-2507.
4. Cohen J: Statistical Power Analysis for the Behavioral Sciences. New York, Academic Press, 1977, pp 19-74.
5. Lionetti V, Recchia FA, Ranieri VM: Overview of ventilator-induced lung injury mechanisms. Curr Opin Crit Care 2005; 11: 82-86.
6. Han B, Lodyga M, Liu M: Ventilator-induced lung injury: role of protein-protein interaction in mechanosensation. Proc Am Thorac Soc 2005; 2: 181-187.
7. Ferguson N, Slutsky A, Kacmarek R: Highfrequency ventilation is/is not the optimal physiological approach to ventilate ARDS patients. J Appl Physiol 2008; 104: 1230-1231.
8. Tsuno K, Prato P, Kolobow T: Acute lung injury from mechanical ventilation at moderately high airway pressures. J Appl Physiol 1990; 69: 956-961.
9. Webb H, Tierney D: Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures. Protection by positive end-expiratory pressure. Am Rev Respir Dis 1974; 110: 556-565.
10. Dreyfuss D, Saumon G: Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998; 157: 294-323. (Pubitemid 28071297)
11. Gattinoni L, D'Andrea L, Pelosi P, Vitale G, Pesenti A, Fumagalli R: Regional effects and mechanism of positive end-expiratory pressure in early adult respiratory distress syndrome. JAMA 1993; 269: 2122-2127.
12. Gattinoni L, Pelosi P, Crotti S, Valenza F: Effects of positive end-expiratory pressure on regional distribution of tidal volume and recruitment in adult respiratory distress syndrome. Am J Respir Crit Care Med 1995; 151: 1807-1814.
13. Martynowicz M, Minor T, Walters B, Hubmayr RD: Regional expansion of oleic acidinjured lungs. Am J Respir Crit Care Med 1999; 160: 250-258.
14. Martynowicz M, Walters B, Hubmayr RD: Mechanisms of recruitment in oleic acid-injured lungs. J Appl Physiol 2001; 90: 1744-1753.
15. Wilson T, Anafi R, Hubmayr RD: Mechanics of edematous lungs. J Appl Physiol 2001; 90: 2088-2093.
16. Wang HM, Bodenstein M, Markstaller K: Overview of the pathology of three widely used animal models of acute lung injury. Eur Surg Res 2008; 40: 305-316.
17. Vadasz I, Morty RE, Kohstall MG, et al: Oleic acid inhibits alveolar fluid reabsorption: a role in acute respiratory distress syndrome? Am J Respir Crit Care Med 2005; 171: 469-479.
18. Derks C, Jakobovitz-Derks D: Embolic pneumopathy induced by oleic acid: a systematic morphologic study. Am J Pathol 1977; 87: 143-158.
19. Miyazawa T, Nakagawa H, Hiramoto M, Arita K, Hiramoto T, Nishida O: Ultrastructural study on the alveolar-capillary injury with pulmonary edema induced by oleic acid in dogs. Hiroshima J Med Sci 1981; 30: 183-190.
20. Kuckelt W, Dauberschmidt R, Bender V, et al: Experimental investigations in adult respiratory distress syndrome (ARDS). Repeated pulmonary lavage in LEWE-minipigs. I. Pulmonary mechanics, gas exchange, and pulmonary hemodynamics. Exp Pathol 1981; 20: 88-104.
21. Holm B, Matalon S: Role of pulmonary surfactant in the development and treatment of adult respiratory distress syndrome. Anesth Analg 1989; 69: 805-818.
22. Huber G, Edmunds L, Finley T: Acute effect of saline lung washing on pulmonary mechanics and morphology. Surg Forum 1966; 17: 113-114.
23. Vangerow B, Hafner D, Rueckoldt H, et al: Effects of C1 inhibitor and r-SP-C surfactant on oxygenation and histology in rats with lavage-induced acute lung injury. Intensive Care Med 2001; 27: 1526-1531.
24. Slutsky A: Lung injury caused by mechanical ventilation. Chest 1999; 116: 9S-15S.
25. Vlahakis N, Hubmayr RD: Cellular stress failure in ventilator-injured lungs. Am J Respir Crit Care Med 2005; 171: 1328-1342.
26. Pinhu L, Whitehead T, Evans T, Griffiths M: Ventilator-associated lung injury. Lancet 2003; 361: 332-340.