High-frequency oscillatory ventilation of the perfluorocarbon-filled lung: Preliminary results in an animal model of acute lung injury

Critical Care Medicine

Volumn 27, Issue 11, 1999, Pages 2500-2507

  Doctor, Allan ^a,d   Mazzoni, Michelle C ^c   DelBalzo, Ughetta ^c   DiCanzio, James ^b   Arnold, John H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c Alliance Pharmaceutical Corporation   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Acute lung injury; Acute respiratory distress syndrome; High frequency oscillatory ventilation; Mechanical ventilation; Partial liquid ventilation; Perfluorochemical; Pulmonary gas exchange; Saline lavage; Surfactant

Indexed keywords

LUNG SURFACTANT; PERFLUOROOCTYL BROMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; ATELECTASIS; HEMODYNAMICS; HIGH FREQUENCY OSCILLATION; HISTOPATHOLOGY; INJURY SCALE; LUNG GAS EXCHANGE; LUNG INJURY; LUNG LAVAGE; LUNG VASCULAR RESISTANCE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032755609     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-199911000-00029     Document Type: Article

References (37)

1. 1. Milberg JA, Davis DR, Steinberg KP, et al: Improved survival of patients with acute respiratory distress syndrome (ARDS): 1983-1993. JAMA 1995; 273:306-309
2. 2. Paulson TE, Spear RM, Peterson BM: New concepts in the treatment of children with acute respiratory distress syndrome. J Pediatr 1995; 127:163-175
3. 3. Davis SL, Furman DP, Costarino AT Jr: Adult respiratory distress syndrome in children: Associated disease, clinical course, and predictors of death. J Pediatr 1993; 123:35-45
4. 4. Timmons OD, Havens PL, Fackler JC, et al: Predicting death in pediatric patients with acute respiratory failure. Chest 1995; 108: 789-797
5. 5. Arnold JH, Truog RD, Thompson JE, et al: High frequency oscillatory ventilation in pediatric respiratory failure. Crit Care Med 1993; 21:272-278
6. 6. Rosenberg RB, Broner CW, Peters KJ, et al: High-frequency ventilation for acute pediatric respiratory failure. Chest 1993; 104: 1216-1221
7. 7. Sarnaik AP, Meert KL, Pappas MD, et al: Predicting outcome in children with severe acute respiratory failure treated with high-frequency ventilation. Crit Care Med 1996; 24:1396-1402
8. 8. Arnold JH, Hanson JH, Toro-Figuero LO, et al: Prospective randomized comparison of high frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Crit Care Med 1994; 22:1530-1539
9. 9. Fuhrman BP: Perfluorocarbon liquids and respiratory support. Crit Care Med 1993; 21: 951-951
10. 10. Leach CL, Fuhrman BP, Morin F III, et al: Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: A prospective, randomized, controlled study. Crit Care Med 1993; 21: 1270-1278
11. 11. Tütüncü AS, Faithfull NS, Lachmann B: Intratracheal perfluorocarbon administration combined with mechanical ventilation in experimental respiratory distress syndrome: Dose-dependent improvement of gas exchange. Crit Care Med 1993; 21:962-969
12. 12. Curtis SE, Peek JT, Kelly DR: Partial liquid breathing with perflubron improves arterial oxygenation in acute canine lung injury. J Appl Physiol 1993; 75:2696-2702
13. 13. Hernan LJ, Fuhrman BP, Papo MC, et al: Cardiorespiratory effects of perfluorocarbon-associated gas exchange at reduced oxygen concentrations. Crit Care Med 1995; 23: 553-559
14. 14. Leach CL, Holm B, Morin FC III, et al: Partial liquid ventilation in premature lambs with respiratory distress syndrome: Efficacy and compatibility with exogenous surfactant. J Pediatr 1995; 126:412-420
15. 15. Leach CL, Greenspan JS, Rubenstein SD, et al: Partial liquid ventilation with perflubron in premature infants with severe respiratory distress syndrome. N Engl J Med 1996; 335: 761-767
16. 16. Nesti FD, Fuhrman BP, Steinhorn DM, et al: Perfluorocarbon-associated gas exchange in gastric aspiration. Crit Care Med 1994; 22: 1445-1452
17. 17. Hirschl RB, Parent A, Tooley R, et al: Liquid ventilation improves pulmonary function, gas exchange, and lung injury in a model of respiratory failure. Ann Surg 1995; 221: 79-88
18. 18. Tütüncü AS, Faithfull NS, Lachmann B: Comparison of ventilatory support with intratracheal perfluorocarbon administration and conventional mechanical ventilation in animals with acute respiratory failure. Am Rev Respir Dis 1993; 148:785-792
19. 19. Lachmann B, Robertson B, Vogel J: In vivo lung lavage as an experimental model of the respiratory distress syndrome. Acta Anaesthesiol Scand 1980; 24:231-236
20. 20. Angus DC, Linde-Zwirble WT, Clermont G, et al: ARDS: Where do all the dollars go? Chest 1996; 110:58S
21. 21. Ring JC, Stidham GL: Novel therapies for acute respiratory failure. Pediatr Clin North Am 1994; 41:1325-1363
22. 22. Gerstmann DR, DeLemos RA, Coalson JJ, et al: Influence of ventilatory technique on pulmonary baroinjury in baboons with hyaline membrane disease. Pediatr Pulmonol 1988; 5:82-91
23. 23. Meredith KS, DeLemos RA, Coalson JJ, et al: Role of lung injury in the pathogenesis of hyaline membrane disease in premature baboons. J Appl Physiol 1989; 66:2150-2158
24. 24. McCulloch PR, Forkert PC, Froese AB: Lung volume maintenance prevents lung injury during high frequency oscillatory ventilation in surfactant-deficient rabbits. Am Rev Respir Dis 1988; 137:1185-1192
25. 25. Sugiura M, McCulloch PR, Wren S, et al: Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung. J Appl Physiol 1994; 77:1355-1365
26. 26. Clark RH, Gerstmann DR, Null DM Jr, et al: Prospective randomized comparison of high frequency oscillatory and conventional ventilation in respiratory distress syndrome. Pediatrics 1992; 89:5-12
27. 27. HiFO Study Group: Randomized study of high-frequency oscillatory ventilation in infants with severe respiratory distress syndrome. J Pediatr 1993; 122:609-619
28. 28. Gerstmann DR, Minton SD, Stoddard RA, et al: The Provo Multicenter early high-frequency oscillatory ventilation trial: Improved pulmonary and clinical outcome in respiratory distress syndrome. Pediatrics 1996; 98:1044-1057
29. 29. Nesti FD, Fuhrman BP, Ballow M, et al: Modulation of PHA responsiveness with perflubron in acid aspiration pneumonitis. Crit Care Med 1995; 23:A213
30. 30. Steinhorn DM, Smith TM, Fuhrman BP: Liquid perflurocarbon (PFC) affects phagocytosis by alveolar macrophages after in vitro exposure. Crit Care Med 1995; 23:A213
31. 31. Smith TM, Steinhorn DM, Thusu K, et al: A liquid perfluorochemical decreases the in vitro production of reactive oxygen species by alveolar macrophages. Crit Care Med 1995; 23:1533-1539
32. 32. Smith KM, Simonton SC, Bing DR, et al: Partial liquid ventilation vs. gas ventilation: histologic differences using high frequency and conventional techniques. Pediatr Res 1996; 39:350A
33. 33. Hernan LJ, Fuhrman BP, Kaiser RE, et al: Perfluorocarbon-associated gas exchange in normal and acid-injured large sheep. Crit Care Med 1996; 24:475-481
34. 34. Papo MC, Paczan PR, Fuhrman BP, et al: Perfluorocarbon-associated gas exchange improves oxygenation, lung mechanics, and survival in a model of adult respiratory distress syndrome. Crit Care Med 1996; 24: 466-474
35. 35. Smith KM, Bing DR, Meyers PA, et al: Partial liquid ventilation using conventional and high frequency techniques. Pediatr Res 1996; 39:351A
36. 36. Leach CL, Sukumar M, Holm BA, et al: High frequency partial Liquid ventilation and surfactant treatment in preterm lambs with respiratory distress syndrome. Pediatr Res 1996; 39:50A
37. 37. Baden HP, Mellema J, Bratton SL, et al: High-frequency oscillatory ventilation with partial liquid ventilation in a model of acute resiratory failure. Pediatr Res 1996; 39:44A